Altered functional brain networks in coronary heart disease: independent component analysis and graph theoretical analysis
This study aimed to explore the association of CHD with functional connectivity and topological properties of brain networks. A total of 27 patients with CHD and 44 healthy controls (HCs) participated in this study and underwent a resting-state functional magnetic resonance imaging (rs-fMRI) scan. Intra- and internetwork functional connectivity alterations were explored using independent component analysis in CHD patients. Furthermore, graph theoretical analysis was adopted to assess abnormalities in small-world properties and network efficiency metrics of brain networks. Compared to HCs, CHD patients exhibited increased f...
Source: Brain Structure and Function - November 9, 2023 Category: Neuroscience Authors: Simin Lin Puyeh Wu Shaoyin Duan Qianni Du Shujia Guo Zhishang Chen Naiming Wu Xiaoyan Chen Ting Xie Yi Han Hengyu Zhao Source Type: research

Neonatal olfactory bulbectomy causes dendritic spine retraction in dorsal hippocampal CA3 neurons in female rats and spatial learning deficits in male rats
The objective of the present study was to evaluate learning and memory capacity and dendritic spine density in dorsal hippocampal CA3 neurons. Seven-day-old male and female Wistar rats were subjected to nOBX by suction, we included an intact group as a control (CON) and a sham-operated group (SHAM), too. Spatial learning and memory were measured at 56 days of age using a Morris water maze. A different cohort of experimental groups was used to measure dendritic spine density by Golgi-Cox impregnation. Male rats with nOBX showed a pronounced spatial learning deficit than female rats. Also, there was a significant decrease in...
Source: Brain Structure and Function - November 9, 2023 Category: Neuroscience Authors: H éctor De La Luz Torres Paola Rojas P érez Adriana Berenice Silva G ómez Source Type: research

Altered functional brain networks in coronary heart disease: independent component analysis and graph theoretical analysis
This study aimed to explore the association of CHD with functional connectivity and topological properties of brain networks. A total of 27 patients with CHD and 44 healthy controls (HCs) participated in this study and underwent a resting-state functional magnetic resonance imaging (rs-fMRI) scan. Intra- and internetwork functional connectivity alterations were explored using independent component analysis in CHD patients. Furthermore, graph theoretical analysis was adopted to assess abnormalities in small-world properties and network efficiency metrics of brain networks. Compared to HCs, CHD patients exhibited increased f...
Source: Brain Structure and Function - November 9, 2023 Category: Neuroscience Authors: Simin Lin Puyeh Wu Shaoyin Duan Qianni Du Shujia Guo Zhishang Chen Naiming Wu Xiaoyan Chen Ting Xie Yi Han Hengyu Zhao Source Type: research

Neonatal olfactory bulbectomy causes dendritic spine retraction in dorsal hippocampal CA3 neurons in female rats and spatial learning deficits in male rats
The objective of the present study was to evaluate learning and memory capacity and dendritic spine density in dorsal hippocampal CA3 neurons. Seven-day-old male and female Wistar rats were subjected to nOBX by suction, we included an intact group as a control (CON) and a sham-operated group (SHAM), too. Spatial learning and memory were measured at 56 days of age using a Morris water maze. A different cohort of experimental groups was used to measure dendritic spine density by Golgi-Cox impregnation. Male rats with nOBX showed a pronounced spatial learning deficit than female rats. Also, there was a significant decrease in...
Source: Brain Structure and Function - November 9, 2023 Category: Neuroscience Authors: H éctor De La Luz Torres Paola Rojas P érez Adriana Berenice Silva G ómez Source Type: research

Altered functional brain networks in coronary heart disease: independent component analysis and graph theoretical analysis
This study aimed to explore the association of CHD with functional connectivity and topological properties of brain networks. A total of 27 patients with CHD and 44 healthy controls (HCs) participated in this study and underwent a resting-state functional magnetic resonance imaging (rs-fMRI) scan. Intra- and internetwork functional connectivity alterations were explored using independent component analysis in CHD patients. Furthermore, graph theoretical analysis was adopted to assess abnormalities in small-world properties and network efficiency metrics of brain networks. Compared to HCs, CHD patients exhibited increased f...
Source: Brain Structure and Function - November 9, 2023 Category: Neuroscience Authors: Simin Lin Puyeh Wu Shaoyin Duan Qianni Du Shujia Guo Zhishang Chen Naiming Wu Xiaoyan Chen Ting Xie Yi Han Hengyu Zhao Source Type: research

Neonatal olfactory bulbectomy causes dendritic spine retraction in dorsal hippocampal CA3 neurons in female rats and spatial learning deficits in male rats
The objective of the present study was to evaluate learning and memory capacity and dendritic spine density in dorsal hippocampal CA3 neurons. Seven-day-old male and female Wistar rats were subjected to nOBX by suction, we included an intact group as a control (CON) and a sham-operated group (SHAM), too. Spatial learning and memory were measured at 56 days of age using a Morris water maze. A different cohort of experimental groups was used to measure dendritic spine density by Golgi-Cox impregnation. Male rats with nOBX showed a pronounced spatial learning deficit than female rats. Also, there was a significant decrease in...
Source: Brain Structure and Function - November 9, 2023 Category: Neuroscience Authors: H éctor De La Luz Torres Paola Rojas P érez Adriana Berenice Silva G ómez Source Type: research

Altered functional brain networks in coronary heart disease: independent component analysis and graph theoretical analysis
This study aimed to explore the association of CHD with functional connectivity and topological properties of brain networks. A total of 27 patients with CHD and 44 healthy controls (HCs) participated in this study and underwent a resting-state functional magnetic resonance imaging (rs-fMRI) scan. Intra- and internetwork functional connectivity alterations were explored using independent component analysis in CHD patients. Furthermore, graph theoretical analysis was adopted to assess abnormalities in small-world properties and network efficiency metrics of brain networks. Compared to HCs, CHD patients exhibited increased f...
Source: Brain Structure and Function - November 9, 2023 Category: Neuroscience Authors: Simin Lin Puyeh Wu Shaoyin Duan Qianni Du Shujia Guo Zhishang Chen Naiming Wu Xiaoyan Chen Ting Xie Yi Han Hengyu Zhao Source Type: research

Neonatal olfactory bulbectomy causes dendritic spine retraction in dorsal hippocampal CA3 neurons in female rats and spatial learning deficits in male rats
The objective of the present study was to evaluate learning and memory capacity and dendritic spine density in dorsal hippocampal CA3 neurons. Seven-day-old male and female Wistar rats were subjected to nOBX by suction, we included an intact group as a control (CON) and a sham-operated group (SHAM), too. Spatial learning and memory were measured at 56 days of age using a Morris water maze. A different cohort of experimental groups was used to measure dendritic spine density by Golgi-Cox impregnation. Male rats with nOBX showed a pronounced spatial learning deficit than female rats. Also, there was a significant decrease in...
Source: Brain Structure and Function - November 9, 2023 Category: Neuroscience Authors: H éctor De La Luz Torres Paola Rojas P érez Adriana Berenice Silva G ómez Source Type: research

Altered functional brain networks in coronary heart disease: independent component analysis and graph theoretical analysis
This study aimed to explore the association of CHD with functional connectivity and topological properties of brain networks. A total of 27 patients with CHD and 44 healthy controls (HCs) participated in this study and underwent a resting-state functional magnetic resonance imaging (rs-fMRI) scan. Intra- and internetwork functional connectivity alterations were explored using independent component analysis in CHD patients. Furthermore, graph theoretical analysis was adopted to assess abnormalities in small-world properties and network efficiency metrics of brain networks. Compared to HCs, CHD patients exhibited increased f...
Source: Brain Structure and Function - November 9, 2023 Category: Neuroscience Authors: Simin Lin Puyeh Wu Shaoyin Duan Qianni Du Shujia Guo Zhishang Chen Naiming Wu Xiaoyan Chen Ting Xie Yi Han Hengyu Zhao Source Type: research

Neonatal olfactory bulbectomy causes dendritic spine retraction in dorsal hippocampal CA3 neurons in female rats and spatial learning deficits in male rats
The objective of the present study was to evaluate learning and memory capacity and dendritic spine density in dorsal hippocampal CA3 neurons. Seven-day-old male and female Wistar rats were subjected to nOBX by suction, we included an intact group as a control (CON) and a sham-operated group (SHAM), too. Spatial learning and memory were measured at 56 days of age using a Morris water maze. A different cohort of experimental groups was used to measure dendritic spine density by Golgi-Cox impregnation. Male rats with nOBX showed a pronounced spatial learning deficit than female rats. Also, there was a significant decrease in...
Source: Brain Structure and Function - November 9, 2023 Category: Neuroscience Authors: H éctor De La Luz Torres Paola Rojas P érez Adriana Berenice Silva G ómez Source Type: research

Altered functional brain networks in coronary heart disease: independent component analysis and graph theoretical analysis
This study aimed to explore the association of CHD with functional connectivity and topological properties of brain networks. A total of 27 patients with CHD and 44 healthy controls (HCs) participated in this study and underwent a resting-state functional magnetic resonance imaging (rs-fMRI) scan. Intra- and internetwork functional connectivity alterations were explored using independent component analysis in CHD patients. Furthermore, graph theoretical analysis was adopted to assess abnormalities in small-world properties and network efficiency metrics of brain networks. Compared to HCs, CHD patients exhibited increased f...
Source: Brain Structure and Function - November 9, 2023 Category: Neuroscience Authors: Simin Lin Puyeh Wu Shaoyin Duan Qianni Du Shujia Guo Zhishang Chen Naiming Wu Xiaoyan Chen Ting Xie Yi Han Hengyu Zhao Source Type: research

Neonatal olfactory bulbectomy causes dendritic spine retraction in dorsal hippocampal CA3 neurons in female rats and spatial learning deficits in male rats
The objective of the present study was to evaluate learning and memory capacity and dendritic spine density in dorsal hippocampal CA3 neurons. Seven-day-old male and female Wistar rats were subjected to nOBX by suction, we included an intact group as a control (CON) and a sham-operated group (SHAM), too. Spatial learning and memory were measured at 56 days of age using a Morris water maze. A different cohort of experimental groups was used to measure dendritic spine density by Golgi-Cox impregnation. Male rats with nOBX showed a pronounced spatial learning deficit than female rats. Also, there was a significant decrease in...
Source: Brain Structure and Function - November 9, 2023 Category: Neuroscience Authors: H éctor De La Luz Torres Paola Rojas P érez Adriana Berenice Silva G ómez Source Type: research

Altered functional brain networks in coronary heart disease: independent component analysis and graph theoretical analysis
This study aimed to explore the association of CHD with functional connectivity and topological properties of brain networks. A total of 27 patients with CHD and 44 healthy controls (HCs) participated in this study and underwent a resting-state functional magnetic resonance imaging (rs-fMRI) scan. Intra- and internetwork functional connectivity alterations were explored using independent component analysis in CHD patients. Furthermore, graph theoretical analysis was adopted to assess abnormalities in small-world properties and network efficiency metrics of brain networks. Compared to HCs, CHD patients exhibited increased f...
Source: Brain Structure and Function - November 9, 2023 Category: Neuroscience Authors: Simin Lin Puyeh Wu Shaoyin Duan Qianni Du Shujia Guo Zhishang Chen Naiming Wu Xiaoyan Chen Ting Xie Yi Han Hengyu Zhao Source Type: research

Neonatal olfactory bulbectomy causes dendritic spine retraction in dorsal hippocampal CA3 neurons in female rats and spatial learning deficits in male rats
The objective of the present study was to evaluate learning and memory capacity and dendritic spine density in dorsal hippocampal CA3 neurons. Seven-day-old male and female Wistar rats were subjected to nOBX by suction, we included an intact group as a control (CON) and a sham-operated group (SHAM), too. Spatial learning and memory were measured at 56 days of age using a Morris water maze. A different cohort of experimental groups was used to measure dendritic spine density by Golgi-Cox impregnation. Male rats with nOBX showed a pronounced spatial learning deficit than female rats. Also, there was a significant decrease in...
Source: Brain Structure and Function - November 9, 2023 Category: Neuroscience Authors: H éctor De La Luz Torres Paola Rojas P érez Adriana Berenice Silva G ómez Source Type: research

Altered functional brain networks in coronary heart disease: independent component analysis and graph theoretical analysis
This study aimed to explore the association of CHD with functional connectivity and topological properties of brain networks. A total of 27 patients with CHD and 44 healthy controls (HCs) participated in this study and underwent a resting-state functional magnetic resonance imaging (rs-fMRI) scan. Intra- and internetwork functional connectivity alterations were explored using independent component analysis in CHD patients. Furthermore, graph theoretical analysis was adopted to assess abnormalities in small-world properties and network efficiency metrics of brain networks. Compared to HCs, CHD patients exhibited increased f...
Source: Brain Structure and Function - November 9, 2023 Category: Neuroscience Authors: Simin Lin Puyeh Wu Shaoyin Duan Qianni Du Shujia Guo Zhishang Chen Naiming Wu Xiaoyan Chen Ting Xie Yi Han Hengyu Zhao Source Type: research