Evolutionary scaling and cognitive correlates of primate frontal cortex microstructure
Brain Struct Funct. 2023 Oct 27. doi: 10.1007/s00429-023-02719-7. Online ahead of print.ABSTRACTInvestigating evolutionary changes in frontal cortex microstructure is crucial to understanding how modifications of neuron and axon distributions contribute to phylogenetic variation in cognition. In the present study, we characterized microstructural components of dorsolateral prefrontal cortex, orbitofrontal cortex, and primary motor cortex from 14 primate species using measurements of neuropil fraction and immunohistochemical markers for fast-spiking inhibitory interneurons, large pyramidal projection neuron subtypes, seroto...
Source: Brain Structure and Function - October 27, 2023 Category: Neuroscience Authors: Cheryl D Stimpson Jeroen B Smaers Mary Ann Raghanti Kimberley A Phillips Bob Jacobs William D Hopkins Patrick R Hof Chet C Sherwood Source Type: research

Different cortical connectivities in human females and males relate to differences in strength and body composition, reward and emotional systems, and memory
Brain Struct Funct. 2023 Oct 20. doi: 10.1007/s00429-023-02720-0. Online ahead of print.ABSTRACTSex differences in human brain structure and function are important, partly because they are likely to be relevant to the male-female differences in behavior and in mental health. To analyse sex differences in cortical function, functional connectivity was measured in 36,531 participants (53% female) in the UK Biobank (mean age 69) using the Human Connectome Project multimodal parcellation atlas with 360 well-specified cortical regions. Most of the functional connectivities were lower in females (Bonferroni corrected), with the ...
Source: Brain Structure and Function - October 20, 2023 Category: Neuroscience Authors: Ruohan Zhang Edmund T Rolls Wei Cheng Jianfeng Feng Source Type: research

Different cortical connectivities in human females and males relate to differences in strength and body composition, reward and emotional systems, and memory
Brain Struct Funct. 2023 Oct 20. doi: 10.1007/s00429-023-02720-0. Online ahead of print.ABSTRACTSex differences in human brain structure and function are important, partly because they are likely to be relevant to the male-female differences in behavior and in mental health. To analyse sex differences in cortical function, functional connectivity was measured in 36,531 participants (53% female) in the UK Biobank (mean age 69) using the Human Connectome Project multimodal parcellation atlas with 360 well-specified cortical regions. Most of the functional connectivities were lower in females (Bonferroni corrected), with the ...
Source: Brain Structure and Function - October 20, 2023 Category: Neuroscience Authors: Ruohan Zhang Edmund T Rolls Wei Cheng Jianfeng Feng Source Type: research

Different cortical connectivities in human females and males relate to differences in strength and body composition, reward and emotional systems, and memory
Brain Struct Funct. 2023 Oct 20. doi: 10.1007/s00429-023-02720-0. Online ahead of print.ABSTRACTSex differences in human brain structure and function are important, partly because they are likely to be relevant to the male-female differences in behavior and in mental health. To analyse sex differences in cortical function, functional connectivity was measured in 36,531 participants (53% female) in the UK Biobank (mean age 69) using the Human Connectome Project multimodal parcellation atlas with 360 well-specified cortical regions. Most of the functional connectivities were lower in females (Bonferroni corrected), with the ...
Source: Brain Structure and Function - October 20, 2023 Category: Neuroscience Authors: Ruohan Zhang Edmund T Rolls Wei Cheng Jianfeng Feng Source Type: research

Different cortical connectivities in human females and males relate to differences in strength and body composition, reward and emotional systems, and memory
Brain Struct Funct. 2023 Oct 20. doi: 10.1007/s00429-023-02720-0. Online ahead of print.ABSTRACTSex differences in human brain structure and function are important, partly because they are likely to be relevant to the male-female differences in behavior and in mental health. To analyse sex differences in cortical function, functional connectivity was measured in 36,531 participants (53% female) in the UK Biobank (mean age 69) using the Human Connectome Project multimodal parcellation atlas with 360 well-specified cortical regions. Most of the functional connectivities were lower in females (Bonferroni corrected), with the ...
Source: Brain Structure and Function - October 20, 2023 Category: Neuroscience Authors: Ruohan Zhang Edmund T Rolls Wei Cheng Jianfeng Feng Source Type: research

Different cortical connectivities in human females and males relate to differences in strength and body composition, reward and emotional systems, and memory
Brain Struct Funct. 2023 Oct 20. doi: 10.1007/s00429-023-02720-0. Online ahead of print.ABSTRACTSex differences in human brain structure and function are important, partly because they are likely to be relevant to the male-female differences in behavior and in mental health. To analyse sex differences in cortical function, functional connectivity was measured in 36,531 participants (53% female) in the UK Biobank (mean age 69) using the Human Connectome Project multimodal parcellation atlas with 360 well-specified cortical regions. Most of the functional connectivities were lower in females (Bonferroni corrected), with the ...
Source: Brain Structure and Function - October 20, 2023 Category: Neuroscience Authors: Ruohan Zhang Edmund T Rolls Wei Cheng Jianfeng Feng Source Type: research

Different cortical connectivities in human females and males relate to differences in strength and body composition, reward and emotional systems, and memory
Brain Struct Funct. 2023 Oct 20. doi: 10.1007/s00429-023-02720-0. Online ahead of print.ABSTRACTSex differences in human brain structure and function are important, partly because they are likely to be relevant to the male-female differences in behavior and in mental health. To analyse sex differences in cortical function, functional connectivity was measured in 36,531 participants (53% female) in the UK Biobank (mean age 69) using the Human Connectome Project multimodal parcellation atlas with 360 well-specified cortical regions. Most of the functional connectivities were lower in females (Bonferroni corrected), with the ...
Source: Brain Structure and Function - October 20, 2023 Category: Neuroscience Authors: Ruohan Zhang Edmund T Rolls Wei Cheng Jianfeng Feng Source Type: research

KIBRA single nucleotide polymorphism is associated with hippocampal subfield volumes and cognition across development
Brain Struct Funct. 2023 Oct 18. doi: 10.1007/s00429-023-02716-w. Online ahead of print.ABSTRACTThe hippocampus (Hc) consists of cytoarchitectonically and functionally distinct subfields: dentate gyrus (DG), cornu ammonis (CA1-3), and subiculum. In adults, a single nucleotide polymorphism (rs17070145, C→ T) in KIBRA, a gene encoding the eponymous (KIdney-BRAin) protein, is associated with variability in Hc subfield volumes and episodic memory. T-allele carriers have larger DG and CA volumes and better episodic memory compared to C-homozygotes. Little is known, however, about KIBRA's role in the development of the brain a...
Source: Brain Structure and Function - October 18, 2023 Category: Neuroscience Authors: Roya Homayouni Ana M Daugherty Qijing Yu Naftali Raz Noa Ofen Source Type: research

KIBRA single nucleotide polymorphism is associated with hippocampal subfield volumes and cognition across development
Brain Struct Funct. 2023 Oct 18. doi: 10.1007/s00429-023-02716-w. Online ahead of print.ABSTRACTThe hippocampus (Hc) consists of cytoarchitectonically and functionally distinct subfields: dentate gyrus (DG), cornu ammonis (CA1-3), and subiculum. In adults, a single nucleotide polymorphism (rs17070145, C→ T) in KIBRA, a gene encoding the eponymous (KIdney-BRAin) protein, is associated with variability in Hc subfield volumes and episodic memory. T-allele carriers have larger DG and CA volumes and better episodic memory compared to C-homozygotes. Little is known, however, about KIBRA's role in the development of the brain a...
Source: Brain Structure and Function - October 18, 2023 Category: Neuroscience Authors: Roya Homayouni Ana M Daugherty Qijing Yu Naftali Raz Noa Ofen Source Type: research

Adult neurogenesis and "immature" neurons in mammals: an evolutionary trade-off in plasticity?
Brain Struct Funct. 2023 Oct 13. doi: 10.1007/s00429-023-02717-9. Online ahead of print.ABSTRACTNeuronal plasticity can vary remarkably in its form and degree across animal species. Adult neurogenesis, namely the capacity to produce new neurons from neural stem cells through adulthood, appears widespread in non-mammalian vertebrates, whereas it is reduced in mammals. A growing body of comparative studies also report variation in the occurrence and activity of neural stem cell niches between mammals, with a general trend of reduction from small-brained to large-brained species. Conversely, recent studies have shown that lar...
Source: Brain Structure and Function - October 13, 2023 Category: Neuroscience Authors: Luca Bonfanti Chiara La Rosa Marco Ghibaudi Chet C Sherwood Source Type: research

Adult neurogenesis and "immature" neurons in mammals: an evolutionary trade-off in plasticity?
Brain Struct Funct. 2023 Oct 13. doi: 10.1007/s00429-023-02717-9. Online ahead of print.ABSTRACTNeuronal plasticity can vary remarkably in its form and degree across animal species. Adult neurogenesis, namely the capacity to produce new neurons from neural stem cells through adulthood, appears widespread in non-mammalian vertebrates, whereas it is reduced in mammals. A growing body of comparative studies also report variation in the occurrence and activity of neural stem cell niches between mammals, with a general trend of reduction from small-brained to large-brained species. Conversely, recent studies have shown that lar...
Source: Brain Structure and Function - October 13, 2023 Category: Neuroscience Authors: Luca Bonfanti Chiara La Rosa Marco Ghibaudi Chet C Sherwood Source Type: research

Adult neurogenesis and "immature" neurons in mammals: an evolutionary trade-off in plasticity?
Brain Struct Funct. 2023 Oct 13. doi: 10.1007/s00429-023-02717-9. Online ahead of print.ABSTRACTNeuronal plasticity can vary remarkably in its form and degree across animal species. Adult neurogenesis, namely the capacity to produce new neurons from neural stem cells through adulthood, appears widespread in non-mammalian vertebrates, whereas it is reduced in mammals. A growing body of comparative studies also report variation in the occurrence and activity of neural stem cell niches between mammals, with a general trend of reduction from small-brained to large-brained species. Conversely, recent studies have shown that lar...
Source: Brain Structure and Function - October 13, 2023 Category: Neuroscience Authors: Luca Bonfanti Chiara La Rosa Marco Ghibaudi Chet C Sherwood Source Type: research

Adult neurogenesis and "immature" neurons in mammals: an evolutionary trade-off in plasticity?
Brain Struct Funct. 2023 Oct 13. doi: 10.1007/s00429-023-02717-9. Online ahead of print.ABSTRACTNeuronal plasticity can vary remarkably in its form and degree across animal species. Adult neurogenesis, namely the capacity to produce new neurons from neural stem cells through adulthood, appears widespread in non-mammalian vertebrates, whereas it is reduced in mammals. A growing body of comparative studies also report variation in the occurrence and activity of neural stem cell niches between mammals, with a general trend of reduction from small-brained to large-brained species. Conversely, recent studies have shown that lar...
Source: Brain Structure and Function - October 13, 2023 Category: Neuroscience Authors: Luca Bonfanti Chiara La Rosa Marco Ghibaudi Chet C Sherwood Source Type: research

Neuroanatomical correlates of aggressiveness: a case-control voxel- and surface-based morphometric study
Brain Struct Funct. 2023 Oct 11. doi: 10.1007/s00429-023-02715-x. Online ahead of print.ABSTRACTAggression occurs across the population ranging on a symptom continuum. Most previous studies have used magnetic resonance imaging in clinical/forensic samples, which is associated with several confounding factors. The present study examined structural brain characteristics in two healthy samples differing only in their propensity for aggressive behavior. Voxel- and surface-based morphometry (SBM) analyses were performed on 29 male martial artists and 32 age-matched male controls. Martial artists had significantly increased mean...
Source: Brain Structure and Function - October 11, 2023 Category: Neuroscience Authors: Stephanie Seidenbecher Maria Sch öne J örn Kaufmann Kolja Schiltz Bernhard Bogerts Thomas Frodl Source Type: research

Whole-brain gray matter maturation trajectories associated with autistic traits from adolescence to early adulthood
Brain Struct Funct. 2023 Oct 11. doi: 10.1007/s00429-023-02710-2. Online ahead of print.ABSTRACTA growing number of evidence supports a continued distribution of autistic traits in the general population. However, brain maturation trajectories of autistic traits as well as the influence of sex on these trajectories remain largely unknown. We investigated the association of autistic traits in the general population, with longitudinal gray matter (GM) maturation trajectories during the critical period of adolescence. We assessed 709 community-based adolescents (54.7% women) at age 14 and 22. After testing the effect of sex, ...
Source: Brain Structure and Function - October 11, 2023 Category: Neuroscience Authors: Guillaume Gros Ruben Miranda Marcos Anthony Latrille Ana Saitovitch Fanny Gollier-Briant Philippe Fossati Liane Schmidt Tobias Banaschewski Gareth J Barker Arun L W Bokde Sylvane Desrivi ères Antoine Grigis Hugh Garavan Penny Gowland Andreas Heinz R üdi Source Type: research