Mutual information of multiple rhythms in schizophrenia
In this study, we investigated multiple oscillatory interactions in schizophrenia using a novel approach based on information theory. This method allowed us to investigate interactions from a new perspective, where two or more rhythm interactions could be analyzed at the same time. We calculated the mutual information of multiple rhythms (MIMR) for EEG segments registered in resting state. Following previous studies, we focused on rhythm interactions between theta, alpha, and gamma. The results showed that, in general, MIMR was higher in patients than in controls for alpha-gamma and theta-gamma couplings. This finding of a...
Source: Brain Structure and Function - December 13, 2023 Category: Neuroscience Authors: Antonio Ib áñez-Molina Yasmina Crespo Cobo Maria Felipa Soriano Pe ña Sergio Iglesias-Parro Juan Ruiz de Miras Source Type: research
Multivariate investigation of aging in mouse models expressing the Alzheimer's protective APOE2 allele: integrating cognitive metrics, brain imaging, and blood transcriptomics
Brain Struct Funct. 2023 Dec 13. doi: 10.1007/s00429-023-02731-x. Online ahead of print.ABSTRACTAPOE allelic variation is critical in brain aging and Alzheimer's disease (AD). The APOE2 allele associated with cognitive resilience and neuroprotection against AD remains understudied. We employed a multipronged approach to characterize the transition from middle to old age in mice with APOE2 allele, using behavioral assessments, image-derived morphometry and diffusion metrics, structural connectomics, and blood transcriptomics. We used sparse multiple canonical correlation analyses (SMCCA) for integrative modeling, and graph ...
Source: Brain Structure and Function - December 13, 2023 Category: Neuroscience Authors: Hae Sol Moon Ali Mahzarnia Jacques Stout Robert J Anderson Madison Strain Jessica T Tremblay Zay Yar Han Andrei Niculescu Anna MacFarlane Jasmine King Allison Ashley-Koch Darin Clark Michael W Lutz Alexandra Badea Source Type: research
Mutual information of multiple rhythms in schizophrenia
In this study, we investigated multiple oscillatory interactions in schizophrenia using a novel approach based on information theory. This method allowed us to investigate interactions from a new perspective, where two or more rhythm interactions could be analyzed at the same time. We calculated the mutual information of multiple rhythms (MIMR) for EEG segments registered in resting state. Following previous studies, we focused on rhythm interactions between theta, alpha, and gamma. The results showed that, in general, MIMR was higher in patients than in controls for alpha-gamma and theta-gamma couplings. This finding of a...
Source: Brain Structure and Function - December 13, 2023 Category: Neuroscience Authors: Antonio Ib áñez-Molina Yasmina Crespo Cobo Maria Felipa Soriano Pe ña Sergio Iglesias-Parro Juan Ruiz de Miras Source Type: research
Multivariate investigation of aging in mouse models expressing the Alzheimer's protective APOE2 allele: integrating cognitive metrics, brain imaging, and blood transcriptomics
Brain Struct Funct. 2023 Dec 13. doi: 10.1007/s00429-023-02731-x. Online ahead of print.ABSTRACTAPOE allelic variation is critical in brain aging and Alzheimer's disease (AD). The APOE2 allele associated with cognitive resilience and neuroprotection against AD remains understudied. We employed a multipronged approach to characterize the transition from middle to old age in mice with APOE2 allele, using behavioral assessments, image-derived morphometry and diffusion metrics, structural connectomics, and blood transcriptomics. We used sparse multiple canonical correlation analyses (SMCCA) for integrative modeling, and graph ...
Source: Brain Structure and Function - December 13, 2023 Category: Neuroscience Authors: Hae Sol Moon Ali Mahzarnia Jacques Stout Robert J Anderson Madison Strain Jessica T Tremblay Zay Yar Han Andrei Niculescu Anna MacFarlane Jasmine King Allison Ashley-Koch Darin Clark Michael W Lutz Alexandra Badea Source Type: research
Mutual information of multiple rhythms in schizophrenia
In this study, we investigated multiple oscillatory interactions in schizophrenia using a novel approach based on information theory. This method allowed us to investigate interactions from a new perspective, where two or more rhythm interactions could be analyzed at the same time. We calculated the mutual information of multiple rhythms (MIMR) for EEG segments registered in resting state. Following previous studies, we focused on rhythm interactions between theta, alpha, and gamma. The results showed that, in general, MIMR was higher in patients than in controls for alpha-gamma and theta-gamma couplings. This finding of a...
Source: Brain Structure and Function - December 13, 2023 Category: Neuroscience Authors: Antonio Ib áñez-Molina Yasmina Crespo Cobo Maria Felipa Soriano Pe ña Sergio Iglesias-Parro Juan Ruiz de Miras Source Type: research
Multivariate investigation of aging in mouse models expressing the Alzheimer's protective APOE2 allele: integrating cognitive metrics, brain imaging, and blood transcriptomics
Brain Struct Funct. 2023 Dec 13. doi: 10.1007/s00429-023-02731-x. Online ahead of print.ABSTRACTAPOE allelic variation is critical in brain aging and Alzheimer's disease (AD). The APOE2 allele associated with cognitive resilience and neuroprotection against AD remains understudied. We employed a multipronged approach to characterize the transition from middle to old age in mice with APOE2 allele, using behavioral assessments, image-derived morphometry and diffusion metrics, structural connectomics, and blood transcriptomics. We used sparse multiple canonical correlation analyses (SMCCA) for integrative modeling, and graph ...
Source: Brain Structure and Function - December 13, 2023 Category: Neuroscience Authors: Hae Sol Moon Ali Mahzarnia Jacques Stout Robert J Anderson Madison Strain Jessica T Tremblay Zay Yar Han Andrei Niculescu Anna MacFarlane Jasmine King Allison Ashley-Koch Darin Clark Michael W Lutz Alexandra Badea Source Type: research
Mutual information of multiple rhythms in schizophrenia
In this study, we investigated multiple oscillatory interactions in schizophrenia using a novel approach based on information theory. This method allowed us to investigate interactions from a new perspective, where two or more rhythm interactions could be analyzed at the same time. We calculated the mutual information of multiple rhythms (MIMR) for EEG segments registered in resting state. Following previous studies, we focused on rhythm interactions between theta, alpha, and gamma. The results showed that, in general, MIMR was higher in patients than in controls for alpha-gamma and theta-gamma couplings. This finding of a...
Source: Brain Structure and Function - December 13, 2023 Category: Neuroscience Authors: Antonio Ib áñez-Molina Yasmina Crespo Cobo Maria Felipa Soriano Pe ña Sergio Iglesias-Parro Juan Ruiz de Miras Source Type: research
Multivariate investigation of aging in mouse models expressing the Alzheimer's protective APOE2 allele: integrating cognitive metrics, brain imaging, and blood transcriptomics
Brain Struct Funct. 2023 Dec 13. doi: 10.1007/s00429-023-02731-x. Online ahead of print.ABSTRACTAPOE allelic variation is critical in brain aging and Alzheimer's disease (AD). The APOE2 allele associated with cognitive resilience and neuroprotection against AD remains understudied. We employed a multipronged approach to characterize the transition from middle to old age in mice with APOE2 allele, using behavioral assessments, image-derived morphometry and diffusion metrics, structural connectomics, and blood transcriptomics. We used sparse multiple canonical correlation analyses (SMCCA) for integrative modeling, and graph ...
Source: Brain Structure and Function - December 13, 2023 Category: Neuroscience Authors: Hae Sol Moon Ali Mahzarnia Jacques Stout Robert J Anderson Madison Strain Jessica T Tremblay Zay Yar Han Andrei Niculescu Anna MacFarlane Jasmine King Allison Ashley-Koch Darin Clark Michael W Lutz Alexandra Badea Source Type: research
Mutual information of multiple rhythms in schizophrenia
In this study, we investigated multiple oscillatory interactions in schizophrenia using a novel approach based on information theory. This method allowed us to investigate interactions from a new perspective, where two or more rhythm interactions could be analyzed at the same time. We calculated the mutual information of multiple rhythms (MIMR) for EEG segments registered in resting state. Following previous studies, we focused on rhythm interactions between theta, alpha, and gamma. The results showed that, in general, MIMR was higher in patients than in controls for alpha-gamma and theta-gamma couplings. This finding of a...
Source: Brain Structure and Function - December 13, 2023 Category: Neuroscience Authors: Antonio Ib áñez-Molina Yasmina Crespo Cobo Maria Felipa Soriano Pe ña Sergio Iglesias-Parro Juan Ruiz de Miras Source Type: research
Multivariate investigation of aging in mouse models expressing the Alzheimer's protective APOE2 allele: integrating cognitive metrics, brain imaging, and blood transcriptomics
Brain Struct Funct. 2023 Dec 13. doi: 10.1007/s00429-023-02731-x. Online ahead of print.ABSTRACTAPOE allelic variation is critical in brain aging and Alzheimer's disease (AD). The APOE2 allele associated with cognitive resilience and neuroprotection against AD remains understudied. We employed a multipronged approach to characterize the transition from middle to old age in mice with APOE2 allele, using behavioral assessments, image-derived morphometry and diffusion metrics, structural connectomics, and blood transcriptomics. We used sparse multiple canonical correlation analyses (SMCCA) for integrative modeling, and graph ...
Source: Brain Structure and Function - December 13, 2023 Category: Neuroscience Authors: Hae Sol Moon Ali Mahzarnia Jacques Stout Robert J Anderson Madison Strain Jessica T Tremblay Zay Yar Han Andrei Niculescu Anna MacFarlane Jasmine King Allison Ashley-Koch Darin Clark Michael W Lutz Alexandra Badea Source Type: research
Mutual information of multiple rhythms in schizophrenia
In this study, we investigated multiple oscillatory interactions in schizophrenia using a novel approach based on information theory. This method allowed us to investigate interactions from a new perspective, where two or more rhythm interactions could be analyzed at the same time. We calculated the mutual information of multiple rhythms (MIMR) for EEG segments registered in resting state. Following previous studies, we focused on rhythm interactions between theta, alpha, and gamma. The results showed that, in general, MIMR was higher in patients than in controls for alpha-gamma and theta-gamma couplings. This finding of a...
Source: Brain Structure and Function - December 13, 2023 Category: Neuroscience Authors: Antonio Ib áñez-Molina Yasmina Crespo Cobo Maria Felipa Soriano Pe ña Sergio Iglesias-Parro Juan Ruiz de Miras Source Type: research
Multivariate investigation of aging in mouse models expressing the Alzheimer's protective APOE2 allele: integrating cognitive metrics, brain imaging, and blood transcriptomics
Brain Struct Funct. 2023 Dec 13. doi: 10.1007/s00429-023-02731-x. Online ahead of print.ABSTRACTAPOE allelic variation is critical in brain aging and Alzheimer's disease (AD). The APOE2 allele associated with cognitive resilience and neuroprotection against AD remains understudied. We employed a multipronged approach to characterize the transition from middle to old age in mice with APOE2 allele, using behavioral assessments, image-derived morphometry and diffusion metrics, structural connectomics, and blood transcriptomics. We used sparse multiple canonical correlation analyses (SMCCA) for integrative modeling, and graph ...
Source: Brain Structure and Function - December 13, 2023 Category: Neuroscience Authors: Hae Sol Moon Ali Mahzarnia Jacques Stout Robert J Anderson Madison Strain Jessica T Tremblay Zay Yar Han Andrei Niculescu Anna MacFarlane Jasmine King Allison Ashley-Koch Darin Clark Michael W Lutz Alexandra Badea Source Type: research
Mutual information of multiple rhythms in schizophrenia
In this study, we investigated multiple oscillatory interactions in schizophrenia using a novel approach based on information theory. This method allowed us to investigate interactions from a new perspective, where two or more rhythm interactions could be analyzed at the same time. We calculated the mutual information of multiple rhythms (MIMR) for EEG segments registered in resting state. Following previous studies, we focused on rhythm interactions between theta, alpha, and gamma. The results showed that, in general, MIMR was higher in patients than in controls for alpha-gamma and theta-gamma couplings. This finding of a...
Source: Brain Structure and Function - December 13, 2023 Category: Neuroscience Authors: Antonio Ib áñez-Molina Yasmina Crespo Cobo Maria Felipa Soriano Pe ña Sergio Iglesias-Parro Juan Ruiz de Miras Source Type: research
Multivariate investigation of aging in mouse models expressing the Alzheimer's protective APOE2 allele: integrating cognitive metrics, brain imaging, and blood transcriptomics
Brain Struct Funct. 2023 Dec 13. doi: 10.1007/s00429-023-02731-x. Online ahead of print.ABSTRACTAPOE allelic variation is critical in brain aging and Alzheimer's disease (AD). The APOE2 allele associated with cognitive resilience and neuroprotection against AD remains understudied. We employed a multipronged approach to characterize the transition from middle to old age in mice with APOE2 allele, using behavioral assessments, image-derived morphometry and diffusion metrics, structural connectomics, and blood transcriptomics. We used sparse multiple canonical correlation analyses (SMCCA) for integrative modeling, and graph ...
Source: Brain Structure and Function - December 13, 2023 Category: Neuroscience Authors: Hae Sol Moon Ali Mahzarnia Jacques Stout Robert J Anderson Madison Strain Jessica T Tremblay Zay Yar Han Andrei Niculescu Anna MacFarlane Jasmine King Allison Ashley-Koch Darin Clark Michael W Lutz Alexandra Badea Source Type: research
Ventral and dorsal aspects of the inferior frontal-occipital fasciculus support verbal semantic access and visually-guided behavioural control
Brain Struct Funct. 2023 Dec 9. doi: 10.1007/s00429-023-02729-5. Online ahead of print.ABSTRACTThe Inferior Frontal Occipital Fasciculus (IFOF) is a major anterior-to-posterior white matter pathway in the ventral human brain that connects parietal, temporal and occipital regions to frontal cortex. It has been implicated in a range of functions, including language, semantics, inhibition and the control of action. The recent research shows that the IFOF can be sub-divided into a ventral and dorsal branch, but the functional relevance of this distinction, as well as any potential hemispheric differences, are poorly understood...
Source: Brain Structure and Function - December 9, 2023 Category: Neuroscience Authors: Tirso R J Gonzalez Alam Juan Cruz Arias Elizabeth Jefferies Jonathan Smallwood Alexander Leemans Julian Marino Davolos Source Type: research
