Comparative transcriptome analysis of heat-induced domesticated zebrafish during gonadal differentiation
The influence of environmental factors, especially temperature, on sex ratio is of great significance to elucidate the mechanism of sex determination. However, the molecular mechanisms by which temperature aff... (Source: BMC Genetics)
Source: BMC Genetics - May 31, 2022 Category: Genetics & Stem Cells Authors: Chenchen Wang, Xuhuai Chen, Yu Dai, Yifei Zhang, Yuandong Sun and Xiaojuan Cui Tags: Research Source Type: research

Exploring the underlying molecular mechanism of liver cancer cells under hypoxia based on RNA sequencing
The aim of our study was to use the differentially expressed mRNAs (DEmRNAs) and differentially expressed miRNAs (DEmiRNAs) to illustrate the underlying mechanism of hypoxia in liver cancer. (Source: BMC Genetics)
Source: BMC Genetics - May 19, 2022 Category: Genetics & Stem Cells Authors: Xin Zhao, Wenpeng Liu, Baowang Liu, Qiang Zeng, Ziqiang Cui, Yang Wang, Jinglin Cao, Qingjun Gao, Caiyan Zhao and Jian Dou Tags: Research Source Type: research

High-resolution detection of quantitative trait loci for seven important yield-related traits in wheat (Triticum aestivum L.) using a high-density SLAF-seq genetic map
Yield-related traits including thousand grain weight (TGW), grain number per spike (GNS), grain width (GW), grain length (GL), plant height (PH), spike length (SL), and spikelet number per spike (SNS) are grea... (Source: BMC Genetics)
Source: BMC Genetics - May 13, 2022 Category: Genetics & Stem Cells Authors: Tao Li, Qiao Li, Jinhui Wang, Zhao Yang, Yanyan Tang, Yan Su, Juanyu Zhang, Xvebing Qiu, Xi Pu, Zhifen Pan, Haili Zhang, Junjun Liang, Zehou Liu, Jun Li, Wuyun Yan, Maoqun Yu & hellip; Tags: Research Source Type: research

Brain region-specific effects of nearly fixed sapiens-derived alleles
The availability of high-coverage genomes of our extinct relatives, the Neanderthals and Denisovans, and the emergence of large, tissue-specific databases of modern human genetic variation, offer the possibili... (Source: BMC Genetics)
Source: BMC Genetics - May 11, 2022 Category: Genetics & Stem Cells Authors: Alejandro Andirk ó and Cedric Boeckx Tags: Research Source Type: research

Identification of key sex-specific pathways and genes in the subcutaneous adipose tissue from pigs using WGCNA method
Adipose tissues (ATs), including visceral ATs (VATs) and subcutaneous ATs (SATs), are crucial for maintaining energy and metabolic homeostasis. SATs have been found to be closely related to obesity and obesity... (Source: BMC Genetics)
Source: BMC Genetics - May 10, 2022 Category: Genetics & Stem Cells Authors: Huiyu Wang, Xiaoyi Wang, Mingli Li, Shuyan Wang, Qiang Chen and Shaoxiong Lu Tags: Research Source Type: research

Correction to: Perspective on the combined use of an independent transgenic sexing and a multifactorial reproductive sterility system to avoid resistance development against transgenic Sterile Insect Technique approaches
(Source: BMC Genetics)
Source: BMC Genetics - May 4, 2022 Category: Genetics & Stem Cells Authors: Kolja N. Eckermann, Stefan Dippel, Mohammad KaramiNejadRanjbar, Hassan M. Ahmed, Ingrid M. Curril and Ernst A. Wimmer Tags: Correction Source Type: research

Genome wide association study on development and evolution of glutinous rice
Glutinous rice as a special endosperm type is consumed as a staple food in East Asian countries by consumers ’ preference. Genetic studies on glutinous rice could be conducive to improve rice quality and unders... (Source: BMC Genetics)
Source: BMC Genetics - May 4, 2022 Category: Genetics & Stem Cells Authors: Conghui Jiang, Muhammad Abdul Rehman Rashid, Yanhong Zhang, Yan Zhao and Yinghua Pan Tags: Research Source Type: research

A database for retrieving information on SARS-CoV-2 S protein mutations based on correlation network analysis
Over a million genomes and mutational analyses of SARS-CoV-2 are available in public databases, which reveal the phylogenetic tree of the virus. Although these data have enabled scientists to closely track the... (Source: BMC Genetics)
Source: BMC Genetics - May 4, 2022 Category: Genetics & Stem Cells Authors: Yoshiyuki Ogata and Ruri Kitayama Tags: Database Source Type: research

Whole genome sequencing and taxonomic profiling of two Pantoea sp. isolated from environmental samples in Israel
As part of a research aiming at the isolation of bacteria secreting growth inhibiting compounds, cultures of Francisella tularensis were implanted in environmental samples and monitored for inhibition zones on ag... (Source: BMC Genetics)
Source: BMC Genetics - April 21, 2022 Category: Genetics & Stem Cells Authors: Yehoudit Guedj-Dana, Inbar Cohen-Gihon, Ofir Israeli, Ohad Shifman, Tamar Aminov, Shahar Rotem, Raphael Ber and Anat Zvi Tags: Data note Source Type: research

An alternative CYB5A transcript is expressed in aneuploid ALL and enriched in relapse
B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is a genetically heterogenous malignancy with poor prognosis in relapsed adult patients. The genetic basis for relapse in aneuploid subtypes such as near... (Source: BMC Genetics)
Source: BMC Genetics - April 18, 2022 Category: Genetics & Stem Cells Authors: Lorenz Bartsch, Michael P. Schroeder, Sonja H änzelmann, Lorenz Bastian, Juan Lázaro-Navarro, Cornelia Schlee, Jutta Ortiz Tanchez, Veronika Schulze, Konstandina Isaakidis, Michael A. Rieger, Nicola Gökbuget, Cornelia Eckert, Hubert Serve, Martin Horst Tags: Research article Source Type: research

Thorough statistical analyses of breast cancer co-methylation patterns
Breast cancer is one of the most commonly diagnosed cancers. It is associated with DNA methylation, an epigenetic event with a methyl group added to a cytosine paired with a guanine, i.e., a CG site. The methy... (Source: BMC Genetics)
Source: BMC Genetics - April 15, 2022 Category: Genetics & Stem Cells Authors: Shuying Sun, Jael Dammann, Pierce Lai and Christine Tian Tags: Research Source Type: research

Sequencing the organelle genomes of Bougainvillea spectabilis and Mirabilis jalapa (Nyctaginaceae)
Mirabilis jalapa L. and Bougainvillea spectabilis are two Mirabilis species known for their ornamental and pharmaceutical values. The organelle genomes are highly conserved with a rapid evolution rate making them... (Source: BMC Genetics)
Source: BMC Genetics - April 13, 2022 Category: Genetics & Stem Cells Authors: Fang Yuan and Xiaozhong Lan Tags: Data note Source Type: research

Deep whole-genome resequencing sheds light on the distribution and effect of amphioxus SNPs
Amphioxus is a model organism for vertebrate evolutionary research. The significant contrast between morphological phenotypic similarity and high-level genetic polymorphism among amphioxus populations has arou... (Source: BMC Genetics)
Source: BMC Genetics - April 8, 2022 Category: Genetics & Stem Cells Authors: Yunchi Zhu, Na Lu, J.-Y. Chen, Chunpeng He, Zhen Huang and Zuhong Lu Tags: Research article Source Type: research

SARS-CoV-2 and human retroelements: a case for molecular mimicry?
The factors driving the late phase of COVID-19 are still poorly understood. However, autoimmunity is an evolving theme in COVID-19 ’s pathogenesis. Additionally, deregulation of human retroelements (RE) is foun... (Source: BMC Genetics)
Source: BMC Genetics - April 8, 2022 Category: Genetics & Stem Cells Authors: Benjamin Florian Koch Tags: Research article Source Type: research

Predicted coronavirus Nsp5 protease cleavage sites in the human proteome
The coronavirus nonstructural protein 5 (Nsp5) is a cysteine protease required for processing the viral polyprotein and is therefore crucial for viral replication. Nsp5 from several coronaviruses have also bee... (Source: BMC Genetics)
Source: BMC Genetics - April 4, 2022 Category: Genetics & Stem Cells Authors: Benjamin M. Scott, Vincent Lacasse, Ditte G. Blom, Peter D. Tonner and Nikolaj S. Blom Tags: Research Source Type: research