Autophagy-mediated expression clusters are involved in immunity regulation of coronary artery disease
The association between autophagy and immunity, including infiltrating immunocytes, immune reaction gene-sets, and HLAs (human leukocyte antigen) gene, remains unclear. The present study aimed to provide a val... (Source: BMC Genetics)
Source: BMC Genetics - April 2, 2022 Category: Genetics & Stem Cells Authors: Jin Lv, Dong Wang and Tian Li Tags: Research Source Type: research
First report of de novo assembly and annotation from brain and blood transcriptome of an anadromous shad, Alosa sapidissima
American shad (Alosa sapidissima) is an important migratory fish under Alosinae and has long been valued for its economic, nutritional and cultural attributes. Overfishing and barriers across the passage made it ... (Source: BMC Genetics)
Source: BMC Genetics - March 28, 2022 Category: Genetics & Stem Cells Authors: Kishor Kumar Sarker, Liang Lu, Junman Huang, Tao Zhou, Li Wang, Yun Hu, Lei Jiang, Habibon Naher, Mohammad Abdul Baki, Anirban Sarker and Chenhong Li Tags: Data note Source Type: research
Whole exome sequencing of pediatric leukemia reveals a novel InDel within FLT-3 gene in AML patient from Mizo tribal population, Northeast India
Leukemia is the most common type of cancer in pediatrics. Genomic mutations contribute towards the molecular mechanism of disease progression and also helps in diagnosis and prognosis. This is the first scient... (Source: BMC Genetics)
Source: BMC Genetics - March 28, 2022 Category: Genetics & Stem Cells Authors: Andrew Vanlallawma, Doris Lallawmzuali, Jeremy L. Pautu, Vinod Scaria, Sridhar Sivasubbu and Nachimuthu Senthil Kumar Tags: Research Source Type: research
Whole-genome resequencing reveals genomic footprints of Italian sweet and hot pepper heirlooms giving insight into genes underlying key agronomic and qualitative traits
Pepper is a major crop species of the Solanaceae family, largely appreciated for its high nutritional and healthy contribution to human diets. In the Mediterranean basin, the favorable pedoclimatic conditions ... (Source: BMC Genetics)
Source: BMC Genetics - March 25, 2022 Category: Genetics & Stem Cells Authors: Salvatore Esposito, Riccardo Aiese Cigliano, Teodoro Cardi and Pasquale Tripodi Tags: Research Source Type: research
MAGE genes encoding for embryonic development in cattle is mainly regulated by zinc finger transcription factor family and slightly by CpG Islands
Melanoma Antigen Genes (MAGEs) are a family of genes that have piqued the interest of scientists for their unique expression pattern. The MAGE genes can be classified into type I MAGEs that expressed in testis... (Source: BMC Genetics)
Source: BMC Genetics - March 18, 2022 Category: Genetics & Stem Cells Authors: Bosenu Abera and Hunduma Dinka Tags: Research Source Type: research
Bioinformatical analysis of the key differentially expressed genes and associations with immune cell infiltration in development of endometriosis
This study explored the key genes related to immune cell infiltration in endometriosis. (Source: BMC Genetics)
Source: BMC Genetics - March 18, 2022 Category: Genetics & Stem Cells Authors: Shengnan Chen, Xiaoshan Chai and Xianqing Wu Tags: Research Source Type: research
Profiles of genetic parameters of body weight and feed efficiency in two divergent broiler lines for meat ultimate pH
Selection for feed efficiency is one of the best ways to decrease poultry production costs and environmental impacts. While literature on its genetic determinism is abundant, it is limited to one or a few peri... (Source: BMC Genetics)
Source: BMC Genetics - March 16, 2022 Category: Genetics & Stem Cells Authors: Quentin Berger, Elodie Guettier, J érémy Bernard, Patrice Ganier, Marine Chahnamian, Elisabeth Le Bihan-Duval and Sandrine Mignon-Grasteau Tags: Research Source Type: research
Transcriptomic profiling of the telomerase transformed Mesenchymal stromal cells derived adipocytes in response to rosiglitazone
Differentiation of Immortalized Human Bone Marrow Mesenchymal Stromal Cells - hTERT (iMSC3) into adipocytes is in vitro model of obesity. In our earlier study, rosiglitazone enhanced adipogenesis particularly ... (Source: BMC Genetics)
Source: BMC Genetics - March 9, 2022 Category: Genetics & Stem Cells Authors: Moza Mohamed Al-Ali, Amir Ali Khan, Abeer Maher Fayyad, Sallam Hasan Abdallah and Muhammad Nasir Khan Khattak Tags: Research Source Type: research
Mitochondria in tumour progression: a network of mtDNA variants in different types of cancer
Mitochondrial participation in tumorigenesis and metastasis has been studied for many years, but several aspects of this mechanism remain unclear, such as the association of mitochondrial DNA (mtDNA) with diff... (Source: BMC Genetics)
Source: BMC Genetics - February 18, 2022 Category: Genetics & Stem Cells Authors: Giovanna C. Cavalcante, Ândrea Ribeiro-dos-Santos and Gilderlanio S. de Araújo Tags: Research Source Type: research
Evaluating the cytotoxicity and pathogenicity of multi-walled carbon nanotube through weighted gene co-expression network analysis: a nanotoxicogenomics study
Multi-walled carbon nanotube (MWCNT) is one of the most momentous carbonaceous nanoparticles which is widely used for various applications such as electronics, vehicles, and therapeutics. However, their possib... (Source: BMC Genetics)
Source: BMC Genetics - February 17, 2022 Category: Genetics & Stem Cells Authors: Shameran Jamal Salih and Mohadeseh Zarei Ghobadi Tags: Research Source Type: research
Exploring the effects of genetic variation on gene regulation in cancer in the context of 3D genome structure
Numerous genome-wide association studies (GWAS) conducted to date revealed genetic variants associated with various diseases, including breast and prostate cancers. Despite the availability of these large-scal... (Source: BMC Genetics)
Source: BMC Genetics - February 17, 2022 Category: Genetics & Stem Cells Authors: Noha Osman, Abd-El-Monsif Shawky and Michal Brylinski Tags: Research Source Type: research
First-degree relationships and genotyping errors deciphered by a high-density SNP array in a Duroc × Iberian pig cross
Two individuals with a first-degree relationship share about 50 percent of their alleles. Parent –offspring relationships cannot be homozygous for alternative alleles (genetic exclusion). (Source: BMC Genetics)
Source: BMC Genetics - February 17, 2022 Category: Genetics & Stem Cells Authors: L. Gomez-Raya, E. G ómez Izquierdo, E. de Mercado de la Peña, F. Garcia-Ruiz and W.M. Rauw Tags: Research Source Type: research
Mechanisms of magnoliae cortex on treating sarcopenia explored by GEO gene sequencing data combined with network pharmacology and molecular docking
Administration of Magnoliae Cortex (MC) could induce remission of cisplatin-induced sarcopenia in mice, however, whether it is effective on sarcopenia patients and the underlying mechanisms remain unclear. (Source: BMC Genetics)
Source: BMC Genetics - February 17, 2022 Category: Genetics & Stem Cells Authors: Xingqi Zhao, Feifei Yuan, Haoyang Wan, Hanjun Qin, Nan Jiang and Bin Yu Tags: Research Source Type: research
Genetic characterization and genome-wide association mapping for stem rust resistance in spring bread wheat
Emerging wheat stem rust races have become a major threat to global wheat production. Finding additional loci responsible for resistance to these races and incorporating them into currently cultivated varietie... (Source: BMC Genetics)
Source: BMC Genetics - February 14, 2022 Category: Genetics & Stem Cells Authors: Elias Shewabez, Endashaw Bekele, Admas Alemu, Laura Mugnai and Wuletaw Tadesse Tags: Research article Source Type: research
Construction and comprehensive analysis of the competing endogenous RNA network in endometrial adenocarcinoma
In this study, we constructed gene co-expression networks to identify key modules and hub genes involved in the pathogenesis... (Source: BMC Genetics)
Source: BMC Genetics - February 6, 2022 Category: Genetics & Stem Cells Authors: Chong Feng, Lei Cui, Zhen Jin, Lei Sun, Xiaoyan Wang, Xinshu Chi, Qian Sun and Siyu Lian Tags: Research Source Type: research
