Comprehensive analysis of m6A regulators and relationship with tumor microenvironment, immunotherapy strategies in colorectal adenocarcinoma
In this study, we aimed to... (Source: BMC Genetics)
Source: BMC Genetics - August 11, 2023 Category: Genetics & Stem Cells Authors: Jian Ji, Shichao Liu, Yongyuan Liang and Guixi Zheng Tags: Research Source Type: research

Transcriptome analysis during vernalization in wheat (Triticum aestivum L.)
Vernalization, as a vital process in the life cycle of winter cereal, has important effects on floral organ formation and flowering time. Many morphological changes together with molecular changes occur during... (Source: BMC Genetics)
Source: BMC Genetics - August 10, 2023 Category: Genetics & Stem Cells Authors: Jiao Wang, Lei Sun, Hongwei Zhang, Bo Jiao, Haibo Wang and Shuo Zhou Tags: Research Source Type: research

An analysis of codon utilization patterns in the chloroplast genomes of three species of Coffea
The chloroplast genome of plants is known for its small size and low mutation and recombination rates, making it a valuable tool in plant phylogeny, molecular evolution, and population genetics studies. Codon ... (Source: BMC Genetics)
Source: BMC Genetics - August 9, 2023 Category: Genetics & Stem Cells Authors: Yaqi Li, Xiang Hu, Mingkun Xiao, Jiaxiong Huang, Yuqiang Lou, Faguang Hu, Xingfei Fu, Yanan Li, Hongyan He and Jinhuan Cheng Tags: Research Source Type: research

The single-cell transcriptome and chromatin accessibility datasets of peripheral blood mononuclear cells in Chinese holstein cattle
This study was performed in the frame of a more extensive study dedicated to the integrated analysis of the single-cell transcriptome and chromatin accessibility datasets of peripheral blood mononuclear cells ... (Source: BMC Genetics)
Source: BMC Genetics - August 7, 2023 Category: Genetics & Stem Cells Authors: Xiao Wang, Yahui Gao, Cong-jun Li, Lingzhao Fang, George E. Liu, Xiuxin Zhao, Yuanpei Zhang, Gaozhan Cai, Guanghui Xue, Yan Liu, Lingling Wang, Fan Zhang, Kun Wang, Miao Zhang, Rongling Li, Yundong Gao & hellip; Tags: Data Note Source Type: research

Transcriptomic comparison of bone marrow CD34  + cells and peripheral blood neutrophils from ET patients with JAK2 or CALR mutations
Essential thrombocythemia (ET) is one of the most common types of Ph-negative myeloproliferative neoplasms, an infrequent group of blood cancers that arise from a CD34  + hematopoietic stem cell (HSC) in the bone ... (Source: BMC Genetics)
Source: BMC Genetics - August 7, 2023 Category: Genetics & Stem Cells Authors: Ana Guijarro-Hern ández and José Luis Vizmanos Tags: Research Source Type: research

A novel SNP in NKX1-2 gene is associated with carcass traits in Dezhou donkey
At present, donkey meat in the market shows an imbalance between supply and demand, and there is an urgent need to cultivate a meat-type Dezhou donkey breed. On the one hand, it can improve the imbalance in th... (Source: BMC Genetics)
Source: BMC Genetics - August 7, 2023 Category: Genetics & Stem Cells Authors: Xinrui Wang, Tianqi Wang, Huili Liang, Liyuan Wang, Faheem Akhtar, Xiaoyuan Shi, Wei Ren, Bingjian Huang, Xiyan Kou, Yinghui Chen, Yandong Zhan and Changfa Wang Tags: Research Source Type: research

Genetic dissection of root architectural plasticity and identification of candidate loci in response to drought stress in bread wheat
The frequency of droughts has dramatically increased over the last 50 years, causing yield declines in cereals, including wheat. Crop varieties with efficient root systems show great potential for plant adapta... (Source: BMC Genetics)
Source: BMC Genetics - July 26, 2023 Category: Genetics & Stem Cells Authors: Nurealam Siddiqui, Melesech T. Gabi, Mohammad Kamruzzaman, Abebaw M. Ambaw, Tesfaye J. Teferi, Said Dadshani, Jens L éon and Agim Ballvora Tags: Research Source Type: research

The G2-Like gene family in Populus trichocarpa: identification, evolution and expression profiles
The Golden2-like (GLK) transcription factors are plant-specific transcription factors (TFs) that perform extensive and significant roles in regulating chloroplast development. Here, genome-wide identification, cl... (Source: BMC Genetics)
Source: BMC Genetics - July 5, 2023 Category: Genetics & Stem Cells Authors: Ruihua Wu, Lin Guo, Yueyang Guo, Lehang Ma, Kehang Xu, Boyu Zhang and Liang Du Tags: Research Source Type: research

Assessing whole-exome sequencing data from undiagnosed Brazilian patients to improve the diagnostic yield of inborn errors of immunity
Inborn error of immunity (IEI) comprises a broad group of inherited immunological disorders that usually display an overlap in many clinical manifestations challenging their diagnosis. The identification of di... (Source: BMC Genetics)
Source: BMC Genetics - June 30, 2023 Category: Genetics & Stem Cells Authors: Cristina Santos Ferreira, Ronaldo da Silva Francisco Junior, Alexandra Lehmkuhl Gerber, Ana Paula de Campos Guimar ães, Flávia Anisio Amendola, Fernanda Pinto-Mariz, Monica Soares de Souza, Patrícia Carvalho Batista Miranda, Zilton Farias Meira de Vasc Tags: Data Note Source Type: research

Pairwise comparative analysis of six haplotype assembly methods based on users ’ experience
A haplotype is a set of DNA variants inherited together from one parent or chromosome. Haplotype information is useful for studying genetic variation and disease association. Haplotype assembly (HA) is a proce... (Source: BMC Genetics)
Source: BMC Genetics - June 29, 2023 Category: Genetics & Stem Cells Authors: Shuying Sun, Flora Cheng, Daphne Han, Sarah Wei, Alice Zhong, Sherwin Massoudian and Alison B. Johnson Tags: Research Source Type: research

Association between SUMF1 polymorphisms and COVID-19 severity
Evidence shows that genetic factors play important roles in the severity of coronavirus disease 2019 (COVID-19). Sulfatase modifying factor 1 (SUMF1) gene is involved in alveolar damage and systemic inflammatory ... (Source: BMC Genetics)
Source: BMC Genetics - June 21, 2023 Category: Genetics & Stem Cells Authors: Shaohui Liang, Huixia Gao, Tongxin He, Li Li, Xin Zhang, Lei Zhao, Jie Chen, Yanyan Xie, Jie Bao, Yong Gao, Erhei Dai and Yuling Wang Tags: Research Source Type: research

A multi-tissue gene expression dataset for hibernating brown bears
Complex physiological adaptations often involve the coordination of molecular responses across multiple tissues. Establishing transcriptomic resources for non-traditional model organisms with phenotypes of int... (Source: BMC Genetics)
Source: BMC Genetics - June 8, 2023 Category: Genetics & Stem Cells Authors: Blair W. Perry, Michael W. Saxton, Heiko T. Jansen, Corey R. Quackenbush, Brandon D. Evans Hutzenbiler, Charles T. Robbins, Joanna L. Kelley and Omar E. Cornejo Tags: Data Note Source Type: research

Correction: Processing genome-wide association studies within a repository of heterogeneous genomic datasets
(Source: BMC Genetics)
Source: BMC Genetics - June 5, 2023 Category: Genetics & Stem Cells Authors: Anna Bernasconi, Arif Canakoglu and Federico Comolli Tags: Correction Source Type: research

The shared genetic architecture of smoking behaviours and psychiatric disorders: evidence from a population-based longitudinal study in England
Considering the co-morbidity of major psychiatric disorders and intelligence with smoking, to increase our understanding of why some people take up smoking or continue to smoke, while others stop smoking witho... (Source: BMC Genetics)
Source: BMC Genetics - May 30, 2023 Category: Genetics & Stem Cells Authors: Olesya Ajnakina and Andrew Steptoe Tags: Research article Source Type: research

DanMAC5: a browser of aggregated sequence variants from 8,671 whole genome sequenced Danish individuals
Allele counts of sequence variants obtained by whole genome sequencing (WGS) often play a central role in interpreting the results of genetic and genomic research. However, such variant counts are not readily ... (Source: BMC Genetics)
Source: BMC Genetics - May 27, 2023 Category: Genetics & Stem Cells Authors: Karina Banasik, Peter L. M øller, Tanya R. Techlo, Peter C. Holm, G. Bragi Walters, Andrés Ingason, Anders Rosengren, Palle D. Rohde, Lisette J. A. Kogelman, David Westergaard, Troels Siggaard, Piotr J. Chmura, Mona A. Chalmer, Ólafur Þ. Magnússon, G Tags: Data note Source Type: research