Identification of metabolism-related genes for predicting peritoneal metastasis in patients with gastric cancer
The reprogramming of metabolism is an important factor in the metastatic process of cancer. In our study, we intended to investigate the predictive value of metabolism-related genes (MRGs) in recurrent gastric... (Source: BMC Genetics)
Source: BMC Genetics - December 12, 2022 Category: Genetics & Stem Cells Authors: Chenyu Tian, Junjie Zhao, Dan Liu, Jie Sun, Chengbo Ji, Quan Jiang, Haojie Li, Xuefei Wang and Yihong Sun Tags: Research Source Type: research

Consequences of aberrated DNA methylation in Colon Adenocarcinoma: a bioinformatic-based multi-approach
The biology of colorectal cancer (CRC) is remained to be elucidated. Numerous genetic and epigenetic modifications are in concert to create and progress CRC. DNA methylation as a principal epigenetic factor ha... (Source: BMC Genetics)
Source: BMC Genetics - November 29, 2022 Category: Genetics & Stem Cells Authors: Arash Moradi, Milad Shahsavari, Erfan Gowdini, Kamal Mohammadian, Aida Alizamir, Mohammad Khalilollahi, Zahara Mohammadi Abgarmi and Shahla Mohammad Ganji Tags: Research Source Type: research

A comprehensive list of human microdeletion and microduplication syndromes
The phenotypic spectrum of human microdeletion and microduplication syndromes (MMS) is heterogeneous but often involves intellectual disability, autism spectrum disorders, dysmorphic features and/or multiple c... (Source: BMC Genetics)
Source: BMC Genetics - November 26, 2022 Category: Genetics & Stem Cells Authors: Alyssa S. Wetzel and Benjamin W. Darbro Tags: Data note Source Type: research

An investigation of codon usage pattern analysis in pancreatitis associated genes
Pancreatitis is an inflammatory disorder resulting from the autoactivation of trypsinogen in the pancreas. The genetic basis of the disease is an old phenomenon, and evidence is accumulating for the involvemen... (Source: BMC Genetics)
Source: BMC Genetics - November 25, 2022 Category: Genetics & Stem Cells Authors: Yuanyang Li, Rekha Khandia, Marios Papadakis, Athanasios Alexiou, Alexander Nikolaevich Simonov and Azmat Ali Khan Tags: Research article Source Type: research

Potential prognostic value of a eight ferroptosis-related lncRNAs model and the correlative immune activity in oral squamous cell carcinoma
To investigate the prognostic value of ferroptosis-related long noncoding RNAs (lncRNAs) in oral squamous cell carcinoma (OSCC) and to construct a prognostic risk and immune activity model. (Source: BMC Genetics)
Source: BMC Genetics - November 16, 2022 Category: Genetics & Stem Cells Authors: Lin Qiu, Anqi Tao, Fei Liu, Xianpeng Ge and Cuiying Li Tags: Research Source Type: research

On the importance of metadata when sharing and opening data
While data sharing increases, most open data are difficult to re-use or to identify due to the lack of related metada. In this editorial, I discussed about the importance of those metadata in the context of ge... (Source: BMC Genetics)
Source: BMC Genetics - November 12, 2022 Category: Genetics & Stem Cells Authors: Francois Sabot Tags: Commentary Source Type: research

De novo genome assembly and analysis of Zalaria sp. Him3, a novel fructooligosaccharides producing yeast
Zalaria sp. Him3 was reported as a novel fructooligosaccharides (FOS) producing yeast. However, Zalaria spp. have not been widely known and have been erroneously classified as a different black yeast, Aureobasid... (Source: BMC Genetics)
Source: BMC Genetics - November 10, 2022 Category: Genetics & Stem Cells Authors: Jun Yoshikawa, Minenosuke Matsutani, Mayumi Maeda, Yutaka Kashiwagi and Kenji Maehashi Tags: Research Source Type: research

Global abundance of short tandem repeats is non-random in rodents and primates
While of predominant abundance across vertebrate genomes and significant biological implications, the relevance of short tandem repeats (STRs) (also known as microsatellites) to speciation remains largely elus... (Source: BMC Genetics)
Source: BMC Genetics - November 3, 2022 Category: Genetics & Stem Cells Authors: Masoud Arabfard, Mahmood Salesi, Yazdan Hassani Nourian, Iman Arabipour, AliMohammad Ali Maddi, Kaveh Kavousi and Mina Ohadi Tags: Research Source Type: research

Identification of quantitative trait loci for related traits of stalk lodging resistance using genome-wide association studies in maize (Zea mays L.)
Stalk lodging is one of the main factors affecting maize (Zea mays L.) yield and limiting mechanized harvesting. Developing maize varieties with high stalk lodging resistance requires exploring the genetic basis ... (Source: BMC Genetics)
Source: BMC Genetics - November 1, 2022 Category: Genetics & Stem Cells Authors: Lifen Wu, Yunxiao Zheng, Fuchao Jiao, Ming Wang, Jing Zhang, Zhongqin Zhang, Yaqun Huang, Xiaoyan Jia, Liying Zhu, Yongfeng Zhao, Jinjie Guo and Jingtang Chen Tags: Research Source Type: research

EchinoDB: an update to the web-based application for genomic and transcriptomic data on echinoderms
Here we release a new version of EchinoDB, EchinoDB v2.0 (https://echinodb.uncc.edu). EchinoDB is a database of genomic and transcriptomic data on echinoderm... (Source: BMC Genetics)
Source: BMC Genetics - October 23, 2022 Category: Genetics & Stem Cells Authors: Varnika Mittal, Robert W. Reid, Denis Jacob Machado, Vladimir Mashanov and Daniel A. Janies Tags: Database Source Type: research

Identification of inflammatory-related gene signatures to predict prognosis of endometrial carcinoma
In this study, we construct... (Source: BMC Genetics)
Source: BMC Genetics - October 7, 2022 Category: Genetics & Stem Cells Authors: Linlin Chen, Guang Zhu, Yanbo Liu, Yupei Shao, Bing Pan and Jianhong Zheng Tags: Research Source Type: research

Ancestry-related distribution of Runs of homozygosity and functional variants in Qatari population
Describing how genetic history shapes the pattern of medically relevant variants could improve the understanding of how specific loci interact with each other and affect diseases and traits prevalence. The Qat... (Source: BMC Genetics)
Source: BMC Genetics - September 21, 2022 Category: Genetics & Stem Cells Authors: Massimo Mezzavilla, Massimiliano Cocca, Pierpaolo Maisano Delser, Ramin Badii, Fatemeh Abbaszadeh, Khalid Abdul Hadi, Girotto Giorgia and Paolo Gasparini Tags: Research Source Type: research

Bioinformatics analysis reveals the potential target of rosiglitazone as an antiangiogenic agent for breast cancer therapy
Several studies have demonstrated the antitumor activity of rosiglitazone (RGZ) in cancer cells, including breast cancer cells. However, the molecular targets of RGZ in the inhibition of angiogenesis in breast... (Source: BMC Genetics)
Source: BMC Genetics - September 16, 2022 Category: Genetics & Stem Cells Authors: Adam Hermawan and Herwandhani Putri Tags: Research Source Type: research

Analysis of protein kinase C (HcPKC) gene expression and single-nucleotide polymorphisms related to inner shell color traits in Hyriopsis cumingii
Protein kinase C (PKC) is a multifunctional serine and PKC can phosphorylate serine residues in the cytoplasmic domain of tyrosinase, thereby regulating the activity of tyrosinase. Activated PKC is bound to th... (Source: BMC Genetics)
Source: BMC Genetics - September 9, 2022 Category: Genetics & Stem Cells Authors: Mengying Zhang, Xiajun Chen, Jinpan Zhang, Baiying Guo, Jiale Li and Zhiyi Bai Tags: Research Source Type: research

Draft genome of the aardaker (Lathyrus tuberosus L.), a tuberous legume
Lathyrus tuberosus is a nitrogen-fixing member of the Fabaceae which forms protein-rich tubers. To aid future domestication programs for this legume plant and facilitate evolutionary studies of tuber formation, ... (Source: BMC Genetics)
Source: BMC Genetics - September 4, 2022 Category: Genetics & Stem Cells Authors: P ádraic J. Flood, Minou Nowrousian, Bruno Huettel, Christian Woehle, Kerstin Becker, Tassilo Erik Wollenweber, Dominik Begerow and Christopher Grefen Tags: Data note Source Type: research