The global carrier frequency and genetic prevalence of Upshaw-Schulman syndrome
Upshaw –Schulman syndrome (USS) is an autosomal recessive disease characterized by thrombotic microangiopathies caused by pathogenic variants in ADAMTS13. We aimed to (1) curate the ADAMTS13 gene pathogenic var... (Source: BMC Genetics)
Source: BMC Genetics - November 17, 2021 Category: Genetics & Stem Cells Authors: Ting Zhao, Shanghua Fan and Liu Sun Tags: Research Source Type: research
Analysis of transcriptomic data sets supports the role of IL-6 in NETosis and immunothrombosis in severe COVID-19
There is an urgent need to understand the key events driving pathogenesis of severe COVID-19 disease, so that precise treatment can be instituted. In this respect NETosis is gaining increased attention in the ... (Source: BMC Genetics)
Source: BMC Genetics - November 14, 2021 Category: Genetics & Stem Cells Authors: Samanwoy Mukhopadhyay, Subrata Sinha and Saroj Kant Mohapatra Tags: Research Source Type: research
In depth analysis of Cyprus-specific mutations of SARS-CoV-2 strains using computational approaches
This study aims to characterize SARS-CoV-2 mutations which are primarily prevalent in the Cypriot population. Moreover, using computational approaches, we assess whether these mutations are associated with cha... (Source: BMC Genetics)
Source: BMC Genetics - November 13, 2021 Category: Genetics & Stem Cells Authors: Anastasis Oulas, Jan Richter, Maria Zanti, Marios Tomazou, Kyriaki Michailidou, Kyproula Christodoulou, Christina Christodoulou and George M. Spyrou Tags: Research Source Type: research
Associations between polymorphisms of SLC22A7, NGFR, ARNTL and PPP2R2B genes and Milk production traits in Chinese Holstein
Our preliminary work confirmed that, SLC22A7 (solute carrier family 22 member 7), NGFR (nerve growth factor receptor), ARNTL (aryl hydrocarbon receptor nuclear translocator like) and PPP2R2B (protein phosphatase ... (Source: BMC Genetics)
Source: BMC Genetics - November 3, 2021 Category: Genetics & Stem Cells Authors: Ruike Jia, Yihan Fu, Lingna Xu, Houcheng Li, Yanhua Li, Lin Liu, Zhu Ma, Dongxiao Sun and Bo Han Tags: Research Source Type: research
Genomic resources of broomcorn millet: demonstration and application of a high-throughput BAC mapping pipeline
With high-efficient water-use and drought tolerance, broomcorn millet has emerged as a candidate for food security. To promote its research process for molecular breeding and functional research, a comprehensi... (Source: BMC Genetics)
Source: BMC Genetics - November 1, 2021 Category: Genetics & Stem Cells Authors: Wei Xu, Mengjie Liang, Xue Yang, Hao Wang and Meizhong Luo Tags: Research Source Type: research
Brain areas involved with obsessive-compulsive disorder present different DNA methylation modulation
Obsessive-compulsive disorder (OCD) is characterized by intrusive thoughts and repetitive actions, that presents the involvement of the cortico-striatal areas. The contribution of environmental risk factors to... (Source: BMC Genetics)
Source: BMC Genetics - October 30, 2021 Category: Genetics & Stem Cells Authors: K átia Cristina de Oliveira, Caroline Camilo, Vinícius Daguano Gastaldi, Arthur Sant’Anna Feltrin, Bianca Cristina Garcia Lisboa, Vanessa de Jesus Rodrigues de Paula, Ariane Cristine Moretto, Beny Lafer, Marcelo Queiroz Hoexter, Euripedes Constantino Tags: Research Source Type: research
RNA-Seq analysis in giant pandas reveals the differential expression of multiple genes involved in cataract formation
The giant panda (Ailuropoda melanoleuca) is an endangered mammalian species native to China. Fewer than 2500 giant pandas are known to exist, many of which are bred in captivity as a means to preserve and repopul... (Source: BMC Genetics)
Source: BMC Genetics - October 27, 2021 Category: Genetics & Stem Cells Authors: Yuyan You, Chao Bai, Xuefeng Liu, Yan Lu, Ting Jia, Maohua Xia, Yanqiang Yin, Wei Wang, Yucun Chen, Chenglin Zhang, Yan Liu, Liqin Wang, Tianchun Pu, Tao Ma, Yanhui Liu, Jun Zhou & hellip; Tags: Research Source Type: research
The performance of common SNP arrays in assigning African mitochondrial haplogroups
Mitochondrial haplogroup assignment is an important tool for forensics and evolutionary genetics. African populations are known to display a high diversity of mitochondrial haplogroups. In this research we exp... (Source: BMC Genetics)
Source: BMC Genetics - October 21, 2021 Category: Genetics & Stem Cells Authors: Imke Lankheet, M ário Vicente, Chiara Barbieri and Carina Schlebusch Tags: Research Source Type: research
Whole genome sequence of a non-toxigenic Corynebacterium diphtheriae strain from a hospital in southeastern China
Sporadic cases of infection with non-toxigenic Corynebacterium diphtheriae (C. diphtheriae) isolates have been reported in regions covered by the Diphtheria-Tetanus-Pertussis vaccine, but no information describin... (Source: BMC Genetics)
Source: BMC Genetics - October 16, 2021 Category: Genetics & Stem Cells Authors: Guogang Li, Sipei Wang, Sheng Zhao, Yangxiao Zhou and Xinling Pan Tags: Research Source Type: research
Identification of common microRNA between COPD and non-small cell lung cancer through pathway enrichment analysis
Different factors have been introduced which influence the pathogenesis of chronic obstructive pulmonary disease (COPD) and non-small cell lung cancer (NSCLC). COPD as an independent factor is involved in the ... (Source: BMC Genetics)
Source: BMC Genetics - October 12, 2021 Category: Genetics & Stem Cells Authors: Amirhossein Fathinavid, Mohadeseh Zarei Ghobadi, Ali Najafi and Ali Masoudi-Nejad Tags: Research Source Type: research
Hsa-mir-548 family expression in human reproductive tissues
Hsa-miR-548ba expressed in ovarian granulosa cells targets PTEN and LIFR, which are essential for ovarian follicle activation and growth. The expression pattern of hsa-miR-548ba correlates with its host gene f... (Source: BMC Genetics)
Source: BMC Genetics - October 8, 2021 Category: Genetics & Stem Cells Authors: Ilmatar Rooda, Birgitta Kaselt, Maria Liivrand, Olli-Pekka Smolander, Andres Salumets and Agne Velthut-Meikas Tags: Research Source Type: research
Genome-wide association studies of yield-related traits in high-latitude japonica rice
Heilongjiang Province is a high-quality japonica rice cultivation area in China. One in ten bowls of Chinese rice is produced here. Increasing yield is one of the main aims of rice production in this area. How... (Source: BMC Genetics)
Source: BMC Genetics - October 5, 2021 Category: Genetics & Stem Cells Authors: Guomin Zhang, Rongsheng Wang, Juntao Ma, Hongru Gao, Lingwei Deng, Nanbo Wang, Yongli Wang, Jun Zhang, Kun Li, Wei Zhang, Fengchen Mu, Hui Liu and Ying Wang Tags: Research Source Type: research
Genomic stability among O3:K6 V. parahaemolyticus pandemic strains isolated between 1996 to 2012 in American countries
The V. parahaemolyticus pandemic clone, results in the development of gastrointestinal illness in humans. Toxigenic strains of this species are frequently isolated from aquatic habitats and organisms such as moll... (Source: BMC Genetics)
Source: BMC Genetics - September 27, 2021 Category: Genetics & Stem Cells Authors: Abraham Guerrero, Bruno Gomez-Gil and Marcial Leonardo Lizarraga-Partida Tags: Research article Source Type: research
Correction to: Transcriptome signature of miRNA-26b KO mouse model suggests novel targets
(Source: BMC Genetics)
Source: BMC Genetics - September 20, 2021 Category: Genetics & Stem Cells Authors: Emiel P. C. van der Vorst, Mario A. A. Pepe, Linsey J. F. Peters, Markus Haberbosch, Yvonne Jansen, Ronald Naumann, Georgios T. Stathopoulos, Christian Weber and Kiril Bidzhekov Tags: Correction Source Type: research
The transcription factor reservoir and chromatin landscape in activated plasmacytoid dendritic cells
Transcription factors (TFs) control gene expression by direct binding to regulatory regions of target genes but also by impacting chromatin landscapes and modulating DNA accessibility for other TFs. In recent ... (Source: BMC Genetics)
Source: BMC Genetics - September 20, 2021 Category: Genetics & Stem Cells Authors: Ritu Mann-N üttel, Shafaqat Ali, Patrick Petzsch, Karl Köhrer, Judith Alferink and Stefanie Scheu Tags: Research Source Type: research
