Mapping methylation quantitative trait loci in cardiac tissues nominates risk loci and biological pathways in congenital heart disease
Most congenital heart defects (CHDs) result from complex interactions among genetic susceptibilities, epigenetic modifications, and maternal environmental exposures. Characterizing the complex relationship bet... (Source: BMC Genetics)
Source: BMC Genetics - June 10, 2021 Category: Genetics & Stem Cells Authors: Ming Li, Chen Lyu, Manyan Huang, Catherine Do, Benjamin Tycko, Philip J. Lupo, Stewart L. MacLeod, Christopher E. Randolph, Nianjun Liu, John S. Witte and Charlotte A. Hobbs Tags: Research article Source Type: research
Comparative transcriptome analysis of Alpinia oxyphylla Miq. reveals tissue-specific expression of flavonoid biosynthesis genes
Alpinia oxyphylla Miq. is an important edible and medicinal herb, and its dried fruits are widely used in traditional herbal medicine. Flavonoids are one of the main chemical compounds in A. oxyphylla; however, t... (Source: BMC Genetics)
Source: BMC Genetics - June 5, 2021 Category: Genetics & Stem Cells Authors: Lin Yuan, Kun Pan, Yonghui Li, Bo Yi and Bingmiao Gao Tags: Research article Source Type: research
Analysis of selection signatures on the Z chromosome of bidirectional selection broiler lines for the assessment of abdominal fat content
The discovery of selection signatures has enabled the identification of genomics regions under selective pressure, enhancing knowledge of evolutionary genotype-phenotypes. Sex chromosomes play an important rol... (Source: BMC Genetics)
Source: BMC Genetics - May 31, 2021 Category: Genetics & Stem Cells Authors: Tao Wang, Meng Zhou, Jing Guo, Yuan-Yuan Guo, Kun Ding, Peng Wang and Zhi-Peng Wang Tags: Research Source Type: research
Chromosomal characteristics of salt stress heritable gene expression in the rice genome
Gene expression is potentially an important heritable quantitative trait that mediates between genetic variation and higher-level complex phenotypes through time and condition-dependent regulatory interactions... (Source: BMC Genetics)
Source: BMC Genetics - May 27, 2021 Category: Genetics & Stem Cells Authors: Matthew T. McGowan, Zhiwu Zhang and Stephen P. Ficklin Tags: Research Source Type: research
Genome-wide (ChIP-seq) identification of target genes regulated by WRKY33 during submergence stress in Arabidopsis
Hypoxia induced by flooding causes significant losses to crop production almost every year. However, the molecular network of submergence signaling pathway is still poorly understood. According to previous stu... (Source: BMC Genetics)
Source: BMC Genetics - May 24, 2021 Category: Genetics & Stem Cells Authors: Junlin Zhang, Bao Liu, Yan Song, Yang Chen, Jiao Fu, Jianquan Liu, Tao Ma, Zhenxiang Xi and Huanhuan Liu Tags: Research article Source Type: research
De novo genome assembly and analysis unveil biosynthetic and metabolic potentials of Pseudomonas fragi A13BB
The role of rhizosphere microbiome in supporting plant growth under biotic stress is well documented. Rhizobacteria ward off phytopathogens through various mechanisms including antibiosis. We sought to recover... (Source: BMC Genetics)
Source: BMC Genetics - May 18, 2021 Category: Genetics & Stem Cells Authors: Opeyemi K. Awolope, Noelle H. O ’Driscoll, Alberto Di Salvo and Andrew J. Lamb Tags: Data note Source Type: research
Association between apolipoprotein gene polymorphisms and hyperlipidemia: a meta-analysis
Hyperlipidemia plays an important role in the etiology of cardio-cerebrovascular disease. Over recent years, a number of studies have explored the impact of apolipoprotein genetic polymorphisms in hyperlipidem... (Source: BMC Genetics)
Source: BMC Genetics - April 9, 2021 Category: Genetics & Stem Cells Authors: Xiao-Ning Zhao, Quan Sun, You-Qin Cao, Xiao Ran and Yu Cao Tags: Research article Source Type: research
Long-term dynamic compression enhancement TGF- β3-induced chondrogenesis in bovine stem cells: a gene expression analysis
Bioengineering has demonstrated the potential of utilising mesenchymal stem cells (MSCs), growth factors, and mechanical stimuli to treat cartilage defects. However, the underlying genes and pathways are large... (Source: BMC Genetics)
Source: BMC Genetics - March 20, 2021 Category: Genetics & Stem Cells Authors: Jishizhan Chen, Lidan Chen, Jia Hua and Wenhui Song Tags: Research article Source Type: research
Cloning and expression analysis of GATA1 gene in Carassius auratus red var
GATA1 is a key transcription factor in the GATA family, and promotes the differentiation and maturation of red blood cell, which is essential for normal hematopoiesis. (Source: BMC Genetics)
Source: BMC Genetics - March 18, 2021 Category: Genetics & Stem Cells Authors: Yusu Tian, Yuandong Sun, Mi Ou, Xiaojuan Cui, Dinggang Zhou and Wen ’an Che Tags: Research article Source Type: research
Enhanced tolerance to drought stress resulting from Caragana korshinskii CkWRKY33 in transgenic Arabidopsis thaliana
It is well known that WRKY transcription factors play important roles in plant growth and development, defense regulation and stress responses. (Source: BMC Genetics)
Source: BMC Genetics - March 10, 2021 Category: Genetics & Stem Cells Authors: Zhen Li, Fengping Liang, Tianbao Zhang, Na Fu, Xinwu Pei and Yan Long Tags: Research article Source Type: research
Genome-wide association studies of plant architecture-related traits and 100-seed weight in soybean landraces
Plant architecture-related traits (e.g., plant height (PH), number of nodes on main stem (NN), branch number (BN) and stem diameter (DI)) and 100-seed weight (100-SW) are important agronomic traits and are clo... (Source: BMC Genetics)
Source: BMC Genetics - March 6, 2021 Category: Genetics & Stem Cells Authors: Xiaoli Zhang, Wentao Ding, Dong Xue, Xiangnan Li, Yang Zhou, Jiacheng Shen, Jianying Feng, Na Guo, Lijuan Qiu, Han Xing and Jinming Zhao Tags: Research article Source Type: research
A simple method to estimate the in-house limit of detection for genetic mutations with low allele frequencies in whole-exome sequencing analysis by next-generation sequencing
Next-generation sequencing (NGS) has profoundly changed the approach to genetic/genomic research. Particularly, the clinical utility of NGS in detecting mutations associated with disease risk has contributed t... (Source: BMC Genetics)
Source: BMC Genetics - February 18, 2021 Category: Genetics & Stem Cells Authors: Takumi Miura, Satoshi Yasuda and Yoji Sato Tags: Methodology article Source Type: research
Pineal gland transcriptomic profiling reveals the differential regulation of lncRNA and mRNA related to prolificacy in STH sheep with two FecB genotypes
Long noncoding RNA (lncRNA) has been identified as important regulator in hypothalamic-pituitary-ovarian axis associated with sheep prolificacy. However, little is known of their expression pattern and potenti... (Source: BMC Genetics)
Source: BMC Genetics - February 18, 2021 Category: Genetics & Stem Cells Authors: Chunyan Li, Xiaoyun He, Zijun Zhang, Chunhuan Ren and Mingxing Chu Tags: Research article Source Type: research
Genetic diversity analysis of brown marmorated stink bug, Halyomorpha halys based on mitochondrial COI and COII haplotypes
In the past decade, the brown marmorated stink bug (BMSB), Halyomorpha halys (Hemiptera: Pentatomidae) has caused extensive damage to global agriculture. As a high-risk pest for many countries, including New Zeal... (Source: BMC Genetics)
Source: BMC Genetics - February 15, 2021 Category: Genetics & Stem Cells Authors: Juncong Yan, Chandan Pal, Diane Anderson, G ábor Vétek, Péter Farkas, Allan Burne, Qing-Hai Fan, Jinping Zhang, Disna N. Gunawardana, Rebijith Kayattukandy Balan, Sherly George and Dongmei Li Tags: Research article Source Type: research
Comparative transcriptome analysis reveals novel insights into transcriptional responses to phosphorus starvation in oil palm (Elaeis guineensis) root
Phosphorus (P), in its orthophosphate form (Pi) is an essential macronutrient for oil palm early growth development in which Pi deficiency could later on be reflected in lower biomass production. Application o... (Source: BMC Genetics)
Source: BMC Genetics - February 5, 2021 Category: Genetics & Stem Cells Authors: Sze-Ling Kong, Siti Nor Akmar Abdullah, Chai-Ling Ho, Mohamed Hanafi bin Musa and Wan-Chin Yeap Tags: Research article Source Type: research
