Pulmonary embolism and 529 human blood metabolites: genetic correlation and two-sample Mendelian randomization study
The incidence of pulmonary embolism complications in the literature ranges from 10 to 50%, with a 0.5 –10% risk of fatal pulmonary embolism. However, the biological cause of pulmonary embolism is unknown. (Source: BMC Genetics)
Source: BMC Genetics - August 29, 2022 Category: Genetics & Stem Cells Authors: Ruoyang Feng, Mengnan Lu, Jiawen Xu, Feng Zhang, Mingyi Yang, Pan Luo, Ke Xu and Peng Xu Tags: Research Source Type: research
Retromer subunit, CfVps35 is required for growth development and pathogenicity of Colletotrichum fructicola
Tea oil is widely used as edible oil in China, which extracted from the seeds of Camellia oleifera. In China, the national oil-tea camellia planting area reached 4.533 million hectares, the output of oil-tea came... (Source: BMC Genetics)
Source: BMC Genetics - August 28, 2022 Category: Genetics & Stem Cells Authors: Xi-Ya Li, Sheng-Pei Zhang and Li He Tags: Research Source Type: research
Screening of primary open-angle glaucoma diagnostic markers based on immune-related genes and immune infiltration
Primary open-angle glaucoma (POAG) continues to be a poorly understood disease. Although there were multiple researches on the identification of POAG biomarkers, few studies systematically revealed the immune-... (Source: BMC Genetics)
Source: BMC Genetics - August 24, 2022 Category: Genetics & Stem Cells Authors: Lingge Suo, Wanwei Dai, Xuejiao Qin, Guanlin Li, Di Zhang, Tian Cheng, Taikang Yao and Chun Zhang Tags: Research Source Type: research
Multiple datasets to explore the molecular mechanism of sepsis
This study aimed to identify potential biomarkers, by means of bioinformatics, affecting the occurrence and development of septic shock. (Source: BMC Genetics)
Source: BMC Genetics - August 15, 2022 Category: Genetics & Stem Cells Authors: Shuang Lin, Bin Luo and Junqi Ma Tags: Research Source Type: research
Bioinformatic analysis of PD-1 checkpoint blockade response in influenza infection
The programmed cell death 1 (PD-1)/PD-1 ligand 1 (PD-L1) signaling pathway is significantly upregulated in influenza virus infection, which impairs the antiviral response. Blocking this signaling pathway may r... (Source: BMC Genetics)
Source: BMC Genetics - August 13, 2022 Category: Genetics & Stem Cells Authors: Huilin Ou, Keda Chen, Linfang Chen and Hongcheng Wu Tags: Research Source Type: research
Genetic diversity of DGAT1 gene linked to milk production in cattle populations of Ethiopia
Diacylglycerol acyl-CoA acyltransferase 1 (DGAT1) has become a promising candidate gene for milk production traits because of its important role as a key enzyme in catalyzing the final step of triglyceride synthe... (Source: BMC Genetics)
Source: BMC Genetics - August 10, 2022 Category: Genetics & Stem Cells Authors: Behailu Samuel, Dejenie Mengistie, Ermias Assefa, Mingue Kang, Chankyu Park, Hailu Dadi and Hunduma Dinka Tags: Research Source Type: research
HYAL3 as a potential novel marker of BLCA patient prognosis
It has been previously demonstrated that hyaluronan (HA) potentially regulates the initiation and propagation of bladder cancer (BLCA). HYAL3 encodes hyaluronidase and is a potential therapeutic target for BLCA. ... (Source: BMC Genetics)
Source: BMC Genetics - August 9, 2022 Category: Genetics & Stem Cells Authors: Jun-peng Liu, Yu-tong Fang, Yi-fan Jiang and Hao Lin Tags: Research Source Type: research
Compendious survey of protein tandem repeats in inbred mouse strains
Short tandem repeats (STRs) play a crucial role in genetic diseases. However, classic disease models such as inbred mice lack such genome wide data in public domain. The examination of STR alleles present in t... (Source: BMC Genetics)
Source: BMC Genetics - August 5, 2022 Category: Genetics & Stem Cells Authors: Ahmed Arslan Tags: Research Source Type: research
Comparative genomics of Leuconostoc lactis strains isolated from human gastrointestinal system and fermented foods microbiomes
Leuconostoc lactis forms a crucial member of the genus Leuconostoc and has been widely used in the fermentation industry to convert raw material into acidified and flavored products in dairy and plant-based food ... (Source: BMC Genetics)
Source: BMC Genetics - August 2, 2022 Category: Genetics & Stem Cells Authors: Ismail Gumustop and Fatih Ortakci Tags: Research Source Type: research
Identification of immune-related and autophagy-related genes for the prediction of survival in bladder cancer
Bladder cancer has the characteristics of high morbidity and mortality, and the prevalence of bladder cancer has been increasing in recent years. Immune and autophagy related genes play important roles in canc... (Source: BMC Genetics)
Source: BMC Genetics - August 1, 2022 Category: Genetics & Stem Cells Authors: Quanfeng Zhu, Lingdi Zhang, Yaping Deng and Leilei Tang Tags: Research Source Type: research
Tandem repeats ubiquitously flank and contribute to translation initiation sites
While the evolutionary divergence of cis-regulatory sequences impacts translation initiation sites (TISs), the implication of tandem repeats (TRs) in TIS selection remains largely elusive. Here, we employed the T... (Source: BMC Genetics)
Source: BMC Genetics - July 27, 2022 Category: Genetics & Stem Cells Authors: Ali M. A. Maddi, Kaveh Kavousi, Masoud Arabfard, Hamid Ohadi and Mina Ohadi Tags: Research Source Type: research
Interleukin 20 receptor subunit beta (IL20RB) predicts poor prognosis and regulates immune cell infiltration in clear cell renal cell carcinoma
Emerging evidence has proven the robust role of tumor mutation burden (TMB) and immune cell infiltration (ICI) in cancer immunotherapy. However, the precise effect of TMB and ICI on clear cell renal cell carci... (Source: BMC Genetics)
Source: BMC Genetics - July 26, 2022 Category: Genetics & Stem Cells Authors: Haoxun Zhang, Yiwen Liu, Bowen Wang and Chunyang Wang Tags: Research Source Type: research
In silico discovery of blood cell macromolecular associations
Physical molecular interactions are the basis of intracellular signalling and gene regulatory networks, and comprehensive, accessible databases are needed for their discovery. Highly correlated transcripts may... (Source: BMC Genetics)
Source: BMC Genetics - July 26, 2022 Category: Genetics & Stem Cells Authors: Kaare M. Gautvik, Daniel Sachse, Alexandra C. Hinton, Ole K. Olstad, Douglas P. Kiel, Yi-Hsiang Hsu, Tor P. Utheim, Christine W. Lary and Sjur Reppe Tags: Research Source Type: research
Revised eutherian gene collections
The most recent research projects in scientific field of eutherian comparative genomics included intentions to sequence every extant eutherian species genome in foreseeable future, so that future revisions and... (Source: BMC Genetics)
Source: BMC Genetics - July 23, 2022 Category: Genetics & Stem Cells Authors: Marko Premzl Tags: Data note Source Type: research
Genome-wide characterization of Salmonella Typhimurium genes required for the fitness under iron restriction
Iron is a crucial element for bacterial survival and virulence. During Salmonella infection, the host utilizes a variety of mechanisms to starve the pathogen from iron. However, Salmonella activates distinctive d... (Source: BMC Genetics)
Source: BMC Genetics - July 22, 2022 Category: Genetics & Stem Cells Authors: Sardar Karash, Tieshan Jiang and Young Min Kwon Tags: Research Source Type: research
