Cerebral cavernous malformation proteins, CCM1, CCM2 and CCM3, are decreased in metastatic lesions in a murine breast carcinoma model
Biotech Histochem. 2024 Jan 31:1-8. doi: 10.1080/10520295.2024.2305114. Online ahead of print.ABSTRACTThree genes are associated with cerebral cavernous malformations (CCMs): CCM1, CCM2 and CCM3. These genes participate in microvascular angiogenesis, cell-to-cell junctions, migration and apoptosis. We evaluated the expression in vivo of CCM genes in primary tumors and metastastases in a murine model of metastatic breast carcinoma. We used cell lines obtained from metastasis of 4T1, 4TLM and 4THM breast cancer to liver and heart. These cells were injected into the mammary ridge of Balb/C female mice. After 27 days, the prim...
Source: Biotechnic and Histochemistry - January 31, 2024 Category: Research Authors: Mansur Cici Sayra Dilmac Gunes Aytac Gamze Tanriover Source Type: research
Relation of Langerhans cell size to buccal carcinoma
Biotech Histochem. 2024 Jan 31:1-8. doi: 10.1080/10520295.2024.2305499. Online ahead of print.ABSTRACTOral cancer decreases quality of life despite timely medical management. The carcinogens in tobacco products and their role in tumorigenesis are well documented. Langerhans cells (LCs) are a subset of antigen-presenting cells (APCs) that monitor the tumor microenvironment and engulf carcinogens and foreign bodies. We investigated the distribution and size of LCs and their relation to the mode of tobacco consumption and clinical outcome in patients with buccal carcinoma. We recruited patients with oral cancer who were sched...
Source: Biotechnic and Histochemistry - January 31, 2024 Category: Research Authors: John Kandam Kulathu Mathew Pranay Gaikwad Rajadoss M K Pandian Grace Rebekah Suganthy Rabi Source Type: research
Effects of an energy drink on myonectin in the liver, kidney and skeletal muscle of exercised rats
Biotech Histochem. 2024 Jan 31:1-7. doi: 10.1080/10520295.2024.2305113. Online ahead of print.ABSTRACTMyonectin is a hormone that is produced mainly by skeletal muscle. We investigated the effects of exercise and energy drink (ED) administration on myonectin expression in skeletal muscle, liver and kidney tissue in rats; myonectin is produced by all three tissues. We used 28 male albino rats in four groups: untreated control (C), exercise (E), energy drink (ED) and exercise + energy drink (E + ED). The E and E + ED groups were exercised using a treadmill for 4 weeks. We also administered 3.5 ml/kg/day ED during week 1, 7 m...
Source: Biotechnic and Histochemistry - January 31, 2024 Category: Research Authors: Emsal Cagla Avcu Vedat Çınar Yavuz Yasul Taner Akbulut Zarife Pancar I Sa Aydemir Suna Aydin Mehmet Hanifi Yalcin Suleyman Aydin Source Type: research
Role of asprosin and meteorin-like peptide in progression of actinic keratosis to squamous cell carcinoma
Biotech Histochem. 2024 Jan 9:1-8. doi: 10.1080/10520295.2024.2302016. Online ahead of print.ABSTRACTSquamous cell carcinoma (SCC) often develops from an underlying premalignant lesion. Factors that affect the progression of actinic keratosis (AK) to invasive SCC are not fully known. Asprosin (ASP) and meteorin-like peptide (METRNL) are adipokines that are involved primarily in glucose metabolism. We investigated the expression of ASP and METRNL in AK and SCC to evaluate the role of these adipokines in the development of SCC. We used 15 SCC specimens, 12 AK specimens and 12 healthy control skin specimens. ASP and METRNL pr...
Source: Biotechnic and Histochemistry - January 9, 2024 Category: Research Authors: Esma Inan Yuksel Demet Cicek Betul Demir Nevin Kocaman Ilknur Calik Tuncay Kuloglu Source Type: research
Role of asprosin and meteorin-like peptide in progression of actinic keratosis to squamous cell carcinoma
Biotech Histochem. 2024 Jan 9:1-8. doi: 10.1080/10520295.2024.2302016. Online ahead of print.ABSTRACTSquamous cell carcinoma (SCC) often develops from an underlying premalignant lesion. Factors that affect the progression of actinic keratosis (AK) to invasive SCC are not fully known. Asprosin (ASP) and meteorin-like peptide (METRNL) are adipokines that are involved primarily in glucose metabolism. We investigated the expression of ASP and METRNL in AK and SCC to evaluate the role of these adipokines in the development of SCC. We used 15 SCC specimens, 12 AK specimens and 12 healthy control skin specimens. ASP and METRNL pr...
Source: Biotechnic and Histochemistry - January 9, 2024 Category: Research Authors: Esma Inan Yuksel Demet Cicek Betul Demir Nevin Kocaman Ilknur Calik Tuncay Kuloglu Source Type: research
Stains recently certified
Biotech Histochem. 2024 Nov;99(1):59. doi: 10.1080/10520295.2024.2286747. Epub 2024 Jan 9.NO ABSTRACTPMID:38193148 | DOI:10.1080/10520295.2024.2286747 (Source: Biotechnic and Histochemistry)
Source: Biotechnic and Histochemistry - January 9, 2024 Category: Research Source Type: research
Histochemical and morphological evaluation of a glyoxal acid-free fixative
Biotech Histochem. 2024 Nov;99(1):49-58. doi: 10.1080/10520295.2023.2300797. Epub 2024 Jan 9.ABSTRACTThe application of most chemical fixatives, such as formalin, in the anatomic pathology laboratory requires safety training and hazardous chemical monitoring due to the toxicity and health risks associated with their use. Consequently, the use of formalin has been banned in most applications in Europe; the primary exception is its use in the histology laboratory in lieu of a suitable and safer alternative. Glyoxal based solutions, several of which are available commercially, are the most promising alternative fixatives, bec...
Source: Biotechnic and Histochemistry - January 2, 2024 Category: Research Authors: Chelsea Peeler Christopher R Pitzer Hector G Paez Sheila Criswell Source Type: research
Histochemical and morphological evaluation of a glyoxal acid-free fixative
Biotech Histochem. 2024 Jan 2:1-10. doi: 10.1080/10520295.2023.2300797. Online ahead of print.ABSTRACTThe application of most chemical fixatives, such as formalin, in the anatomic pathology laboratory requires safety training and hazardous chemical monitoring due to the toxicity and health risks associated with their use. Consequently, the use of formalin has been banned in most applications in Europe; the primary exception is its use in the histology laboratory in lieu of a suitable and safer alternative. Glyoxal based solutions, several of which are available commercially, are the most promising alternative fixatives, be...
Source: Biotechnic and Histochemistry - January 2, 2024 Category: Research Authors: Chelsea Peeler Christopher R Pitzer Hector G Paez Sheila Criswell Source Type: research
Histochemical and morphological evaluation of a glyoxal acid-free fixative
Biotech Histochem. 2024 Jan 2:1-10. doi: 10.1080/10520295.2023.2300797. Online ahead of print.ABSTRACTThe application of most chemical fixatives, such as formalin, in the anatomic pathology laboratory requires safety training and hazardous chemical monitoring due to the toxicity and health risks associated with their use. Consequently, the use of formalin has been banned in most applications in Europe; the primary exception is its use in the histology laboratory in lieu of a suitable and safer alternative. Glyoxal based solutions, several of which are available commercially, are the most promising alternative fixatives, be...
Source: Biotechnic and Histochemistry - January 2, 2024 Category: Research Authors: Chelsea Peeler Christopher R Pitzer Hector G Paez Sheila Criswell Source Type: research
Histochemical and morphological evaluation of a glyoxal acid-free fixative
Biotech Histochem. 2024 Jan 2:1-10. doi: 10.1080/10520295.2023.2300797. Online ahead of print.ABSTRACTThe application of most chemical fixatives, such as formalin, in the anatomic pathology laboratory requires safety training and hazardous chemical monitoring due to the toxicity and health risks associated with their use. Consequently, the use of formalin has been banned in most applications in Europe; the primary exception is its use in the histology laboratory in lieu of a suitable and safer alternative. Glyoxal based solutions, several of which are available commercially, are the most promising alternative fixatives, be...
Source: Biotechnic and Histochemistry - January 2, 2024 Category: Research Authors: Chelsea Peeler Christopher R Pitzer Hector G Paez Sheila Criswell Source Type: research
Histochemical and morphological evaluation of a glyoxal acid-free fixative
Biotech Histochem. 2024 Jan 2:1-10. doi: 10.1080/10520295.2023.2300797. Online ahead of print.ABSTRACTThe application of most chemical fixatives, such as formalin, in the anatomic pathology laboratory requires safety training and hazardous chemical monitoring due to the toxicity and health risks associated with their use. Consequently, the use of formalin has been banned in most applications in Europe; the primary exception is its use in the histology laboratory in lieu of a suitable and safer alternative. Glyoxal based solutions, several of which are available commercially, are the most promising alternative fixatives, be...
Source: Biotechnic and Histochemistry - January 2, 2024 Category: Research Authors: Chelsea Peeler Christopher R Pitzer Hector G Paez Sheila Criswell Source Type: research
Histochemical and morphological evaluation of a glyoxal acid-free fixative
Biotech Histochem. 2024 Jan 2:1-10. doi: 10.1080/10520295.2023.2300797. Online ahead of print.ABSTRACTThe application of most chemical fixatives, such as formalin, in the anatomic pathology laboratory requires safety training and hazardous chemical monitoring due to the toxicity and health risks associated with their use. Consequently, the use of formalin has been banned in most applications in Europe; the primary exception is its use in the histology laboratory in lieu of a suitable and safer alternative. Glyoxal based solutions, several of which are available commercially, are the most promising alternative fixatives, be...
Source: Biotechnic and Histochemistry - January 2, 2024 Category: Research Authors: Chelsea Peeler Christopher R Pitzer Hector G Paez Sheila Criswell Source Type: research
Evaluation of ABCB5 immunostained epithelial stem cells in oral squamous cell carcinoma, inflammatory gingival hyperplasia and normal mucosa
Biotech Histochem. 2023 Dec 11:1-5. doi: 10.1080/10520295.2023.2292062. Online ahead of print.ABSTRACTOral cancer is the most prevalent head and neck cancer. Although tumor markers have been investigated for detecting the progression and prognosis of oral cancer, no reliable marker has been identified. We investigated the expression of ATP binding cassette subfamily B member 5 (ABCB5) positive stem cells in oral squamous cell carcinoma (OSCC) and in inflammatory gingival hyperplasia. We used tissue samples from normal subjects, patients with inflammatory gingival hyperplasia, and patients with OSCC. Samples were investigat...
Source: Biotechnic and Histochemistry - December 11, 2023 Category: Research Authors: M G Aadithi Bose Divya G Nandhini Krishnan Rajkumar A Ramesh Kumar R Sarangarajan Source Type: research
Evaluation of ABCB5 immunostained epithelial stem cells in oral squamous cell carcinoma, inflammatory gingival hyperplasia and normal mucosa
Biotech Histochem. 2023 Dec 11:1-5. doi: 10.1080/10520295.2023.2292062. Online ahead of print.ABSTRACTOral cancer is the most prevalent head and neck cancer. Although tumor markers have been investigated for detecting the progression and prognosis of oral cancer, no reliable marker has been identified. We investigated the expression of ATP binding cassette subfamily B member 5 (ABCB5) positive stem cells in oral squamous cell carcinoma (OSCC) and in inflammatory gingival hyperplasia. We used tissue samples from normal subjects, patients with inflammatory gingival hyperplasia, and patients with OSCC. Samples were investigat...
Source: Biotechnic and Histochemistry - December 11, 2023 Category: Research Authors: M G Aadithi Bose Divya G Nandhini Krishnan Rajkumar A Ramesh Kumar R Sarangarajan Source Type: research
Evaluation of ABCB5 immunostained epithelial stem cells in oral squamous cell carcinoma, inflammatory gingival hyperplasia and normal mucosa
Biotech Histochem. 2023 Dec 11:1-5. doi: 10.1080/10520295.2023.2292062. Online ahead of print.ABSTRACTOral cancer is the most prevalent head and neck cancer. Although tumor markers have been investigated for detecting the progression and prognosis of oral cancer, no reliable marker has been identified. We investigated the expression of ATP binding cassette subfamily B member 5 (ABCB5) positive stem cells in oral squamous cell carcinoma (OSCC) and in inflammatory gingival hyperplasia. We used tissue samples from normal subjects, patients with inflammatory gingival hyperplasia, and patients with OSCC. Samples were investigat...
Source: Biotechnic and Histochemistry - December 11, 2023 Category: Research Authors: M G Aadithi Bose Divya G Nandhini Krishnan Rajkumar A Ramesh Kumar R Sarangarajan Source Type: research
