Effects of < em > Polygonum cognatum < /em > Meissn. extract on indomethacin induced gastric damage in rats
Biotech Histochem. 2023 Jun 9:1-8. doi: 10.1080/10520295.2023.2221040. Online ahead of print.ABSTRACTWe investigated the anti-ulcer activity of ethanol extracts of Polygonum cognatum on indomethacin induced gastric damage in rats. We evaluated the number of ulcer areas, oxidant and antioxidant parameters as well as histopathologic features in rat stomach. We measured the total antioxidant status of P. cognatum in concentrations from 1.56-100 mg/ml. P. cognatum extract inhibited indomethacin induced ulcer formation with an effect similar to a 20 mg/kg dose of the standard anti-ulcer drug, esomeprazole. All doses of P. cogna...
Source: Biotechnic and Histochemistry - June 9, 2023 Category: Research Authors: Yasin Bayir Nermin Tagiyeva Abdulmecit Albayrak Abbas Ismayilov Erol Akpinar Erdem Toktay Esen Sezen Karaoglan Kushver Memmedova Zekai Halici Nilufar Rustemova Source Type: research
Effects of < em > Polygonum cognatum < /em > Meissn. extract on indomethacin induced gastric damage in rats
Biotech Histochem. 2023 Jun 9:1-8. doi: 10.1080/10520295.2023.2221040. Online ahead of print.ABSTRACTWe investigated the anti-ulcer activity of ethanol extracts of Polygonum cognatum on indomethacin induced gastric damage in rats. We evaluated the number of ulcer areas, oxidant and antioxidant parameters as well as histopathologic features in rat stomach. We measured the total antioxidant status of P. cognatum in concentrations from 1.56-100 mg/ml. P. cognatum extract inhibited indomethacin induced ulcer formation with an effect similar to a 20 mg/kg dose of the standard anti-ulcer drug, esomeprazole. All doses of P. cogna...
Source: Biotechnic and Histochemistry - June 9, 2023 Category: Research Authors: Yasin Bayir Nermin Tagiyeva Abdulmecit Albayrak Abbas Ismayilov Erol Akpinar Erdem Toktay Esen Sezen Karaoglan Kushver Memmedova Zekai Halici Nilufar Rustemova Source Type: research
Effects of < em > Polygonum cognatum < /em > Meissn. extract on indomethacin induced gastric damage in rats
Biotech Histochem. 2023 Jun 9:1-8. doi: 10.1080/10520295.2023.2221040. Online ahead of print.ABSTRACTWe investigated the anti-ulcer activity of ethanol extracts of Polygonum cognatum on indomethacin induced gastric damage in rats. We evaluated the number of ulcer areas, oxidant and antioxidant parameters as well as histopathologic features in rat stomach. We measured the total antioxidant status of P. cognatum in concentrations from 1.56-100 mg/ml. P. cognatum extract inhibited indomethacin induced ulcer formation with an effect similar to a 20 mg/kg dose of the standard anti-ulcer drug, esomeprazole. All doses of P. cogna...
Source: Biotechnic and Histochemistry - June 9, 2023 Category: Research Authors: Yasin Bayir Nermin Tagiyeva Abdulmecit Albayrak Abbas Ismayilov Erol Akpinar Erdem Toktay Esen Sezen Karaoglan Kushver Memmedova Zekai Halici Nilufar Rustemova Source Type: research
Effects of < em > Polygonum cognatum < /em > Meissn. extract on indomethacin induced gastric damage in rats
Biotech Histochem. 2023 Jun 9:1-8. doi: 10.1080/10520295.2023.2221040. Online ahead of print.ABSTRACTWe investigated the anti-ulcer activity of ethanol extracts of Polygonum cognatum on indomethacin induced gastric damage in rats. We evaluated the number of ulcer areas, oxidant and antioxidant parameters as well as histopathologic features in rat stomach. We measured the total antioxidant status of P. cognatum in concentrations from 1.56-100 mg/ml. P. cognatum extract inhibited indomethacin induced ulcer formation with an effect similar to a 20 mg/kg dose of the standard anti-ulcer drug, esomeprazole. All doses of P. cogna...
Source: Biotechnic and Histochemistry - June 9, 2023 Category: Research Authors: Yasin Bayir Nermin Tagiyeva Abdulmecit Albayrak Abbas Ismayilov Erol Akpinar Erdem Toktay Esen Sezen Karaoglan Kushver Memmedova Zekai Halici Nilufar Rustemova Source Type: research
Effects of < em > Polygonum cognatum < /em > Meissn. extract on indomethacin induced gastric damage in rats
Biotech Histochem. 2023 Jun 9:1-8. doi: 10.1080/10520295.2023.2221040. Online ahead of print.ABSTRACTWe investigated the anti-ulcer activity of ethanol extracts of Polygonum cognatum on indomethacin induced gastric damage in rats. We evaluated the number of ulcer areas, oxidant and antioxidant parameters as well as histopathologic features in rat stomach. We measured the total antioxidant status of P. cognatum in concentrations from 1.56-100 mg/ml. P. cognatum extract inhibited indomethacin induced ulcer formation with an effect similar to a 20 mg/kg dose of the standard anti-ulcer drug, esomeprazole. All doses of P. cogna...
Source: Biotechnic and Histochemistry - June 9, 2023 Category: Research Authors: Yasin Bayir Nermin Tagiyeva Abdulmecit Albayrak Abbas Ismayilov Erol Akpinar Erdem Toktay Esen Sezen Karaoglan Kushver Memmedova Zekai Halici Nilufar Rustemova Source Type: research
Effects of < em > Polygonum cognatum < /em > Meissn. extract on indomethacin induced gastric damage in rats
Biotech Histochem. 2023 Jun 9:1-8. doi: 10.1080/10520295.2023.2221040. Online ahead of print.ABSTRACTWe investigated the anti-ulcer activity of ethanol extracts of Polygonum cognatum on indomethacin induced gastric damage in rats. We evaluated the number of ulcer areas, oxidant and antioxidant parameters as well as histopathologic features in rat stomach. We measured the total antioxidant status of P. cognatum in concentrations from 1.56-100 mg/ml. P. cognatum extract inhibited indomethacin induced ulcer formation with an effect similar to a 20 mg/kg dose of the standard anti-ulcer drug, esomeprazole. All doses of P. cogna...
Source: Biotechnic and Histochemistry - June 9, 2023 Category: Research Authors: Yasin Bayir Nermin Tagiyeva Abdulmecit Albayrak Abbas Ismayilov Erol Akpinar Erdem Toktay Esen Sezen Karaoglan Kushver Memmedova Zekai Halici Nilufar Rustemova Source Type: research
Effects of < em > Polygonum cognatum < /em > Meissn. extract on indomethacin induced gastric damage in rats
Biotech Histochem. 2023 Jun 9:1-8. doi: 10.1080/10520295.2023.2221040. Online ahead of print.ABSTRACTWe investigated the anti-ulcer activity of ethanol extracts of Polygonum cognatum on indomethacin induced gastric damage in rats. We evaluated the number of ulcer areas, oxidant and antioxidant parameters as well as histopathologic features in rat stomach. We measured the total antioxidant status of P. cognatum in concentrations from 1.56-100 mg/ml. P. cognatum extract inhibited indomethacin induced ulcer formation with an effect similar to a 20 mg/kg dose of the standard anti-ulcer drug, esomeprazole. All doses of P. cogna...
Source: Biotechnic and Histochemistry - June 9, 2023 Category: Research Authors: Yasin Bayir Nermin Tagiyeva Abdulmecit Albayrak Abbas Ismayilov Erol Akpinar Erdem Toktay Esen Sezen Karaoglan Kushver Memmedova Zekai Halici Nilufar Rustemova Source Type: research
Silymarin protects against doxorubicin induced cardiotoxicity by down-regulating topoisomerase II β expression in mice
Biotech Histochem. 2023 Jun 5:1-12. doi: 10.1080/10520295.2023.2218648. Online ahead of print.ABSTRACTWe investigated the potential protective effects of silymarin (SLY) on doxorubicin (DOX) induced chronic cardiotoxicity in mice. We used 30 male BALB/c mice assigned randomly to four experimental groups: control group administered normal saline orally daily and intraperitoneally (i.p.) twice/week during weeks 1, 2, 5 and 6; SLY group (was administered 100 mg/kg SLY daily by oral gavage for 6 weeks; DOX group was administered 3 mg/kg DOX i.p. twice/week during weeks 1, 2, 5 and 6; DOX + SLY group administered DOX and SLY co...
Source: Biotechnic and Histochemistry - June 5, 2023 Category: Research Authors: Emrah İpek Recai Tunca Source Type: research
Silymarin protects against doxorubicin induced cardiotoxicity by down-regulating topoisomerase II β expression in mice
Biotech Histochem. 2023 Jun 5:1-12. doi: 10.1080/10520295.2023.2218648. Online ahead of print.ABSTRACTWe investigated the potential protective effects of silymarin (SLY) on doxorubicin (DOX) induced chronic cardiotoxicity in mice. We used 30 male BALB/c mice assigned randomly to four experimental groups: control group administered normal saline orally daily and intraperitoneally (i.p.) twice/week during weeks 1, 2, 5 and 6; SLY group (was administered 100 mg/kg SLY daily by oral gavage for 6 weeks; DOX group was administered 3 mg/kg DOX i.p. twice/week during weeks 1, 2, 5 and 6; DOX + SLY group administered DOX and SLY co...
Source: Biotechnic and Histochemistry - June 5, 2023 Category: Research Authors: Emrah İpek Recai Tunca Source Type: research
Silymarin protects against doxorubicin induced cardiotoxicity by down-regulating topoisomerase II β expression in mice
Biotech Histochem. 2023 Jun 5:1-12. doi: 10.1080/10520295.2023.2218648. Online ahead of print.ABSTRACTWe investigated the potential protective effects of silymarin (SLY) on doxorubicin (DOX) induced chronic cardiotoxicity in mice. We used 30 male BALB/c mice assigned randomly to four experimental groups: control group administered normal saline orally daily and intraperitoneally (i.p.) twice/week during weeks 1, 2, 5 and 6; SLY group (was administered 100 mg/kg SLY daily by oral gavage for 6 weeks; DOX group was administered 3 mg/kg DOX i.p. twice/week during weeks 1, 2, 5 and 6; DOX + SLY group administered DOX and SLY co...
Source: Biotechnic and Histochemistry - June 5, 2023 Category: Research Authors: Emrah İpek Recai Tunca Source Type: research
Silymarin protects against doxorubicin induced cardiotoxicity by down-regulating topoisomerase II β expression in mice
Biotech Histochem. 2023 Jun 5:1-12. doi: 10.1080/10520295.2023.2218648. Online ahead of print.ABSTRACTWe investigated the potential protective effects of silymarin (SLY) on doxorubicin (DOX) induced chronic cardiotoxicity in mice. We used 30 male BALB/c mice assigned randomly to four experimental groups: control group administered normal saline orally daily and intraperitoneally (i.p.) twice/week during weeks 1, 2, 5 and 6; SLY group (was administered 100 mg/kg SLY daily by oral gavage for 6 weeks; DOX group was administered 3 mg/kg DOX i.p. twice/week during weeks 1, 2, 5 and 6; DOX + SLY group administered DOX and SLY co...
Source: Biotechnic and Histochemistry - June 5, 2023 Category: Research Authors: Emrah İpek Recai Tunca Source Type: research
Modeling the extent of conjugation in histochemical dyes and fluorescent probes: clarification in calculating conjugated bond number (CBN) and introduction of a new parameter, resonance energy
Biotech Histochem. 2023 May 25:1-5. doi: 10.1080/10520295.2023.2215547. Online ahead of print.ABSTRACTDetermining the extent of conjugation in dyes and fluorochromes is a helpful tool for understanding or predicting the behavior of these compounds when used as stains for microscopy. One measure that has been used repeatedly is conjugated bond number (CBN), which is the number of bonds in a conjugated system. CBN can be obtained by inspection of the structure of a compound, but the rules for how to determine what constitutes a conjugated system are not fully established. Using molecular modeling software, we have defined mo...
Source: Biotechnic and Histochemistry - May 25, 2023 Category: Research Authors: Richard W Dapson Richard W Horobin Source Type: research
Modeling the extent of conjugation in histochemical dyes and fluorescent probes: clarification in calculating conjugated bond number (CBN) and introduction of a new parameter, resonance energy
Biotech Histochem. 2023 May 25:1-5. doi: 10.1080/10520295.2023.2215547. Online ahead of print.ABSTRACTDetermining the extent of conjugation in dyes and fluorochromes is a helpful tool for understanding or predicting the behavior of these compounds when used as stains for microscopy. One measure that has been used repeatedly is conjugated bond number (CBN), which is the number of bonds in a conjugated system. CBN can be obtained by inspection of the structure of a compound, but the rules for how to determine what constitutes a conjugated system are not fully established. Using molecular modeling software, we have defined mo...
Source: Biotechnic and Histochemistry - May 25, 2023 Category: Research Authors: Richard W Dapson Richard W Horobin Source Type: research
Modeling the extent of conjugation in histochemical dyes and fluorescent probes: clarification in calculating conjugated bond number (CBN) and introduction of a new parameter, resonance energy
Biotech Histochem. 2023 May 25:1-5. doi: 10.1080/10520295.2023.2215547. Online ahead of print.ABSTRACTDetermining the extent of conjugation in dyes and fluorochromes is a helpful tool for understanding or predicting the behavior of these compounds when used as stains for microscopy. One measure that has been used repeatedly is conjugated bond number (CBN), which is the number of bonds in a conjugated system. CBN can be obtained by inspection of the structure of a compound, but the rules for how to determine what constitutes a conjugated system are not fully established. Using molecular modeling software, we have defined mo...
Source: Biotechnic and Histochemistry - May 25, 2023 Category: Research Authors: Richard W Dapson Richard W Horobin Source Type: research
Modeling the extent of conjugation in histochemical dyes and fluorescent probes: clarification in calculating conjugated bond number (CBN) and introduction of a new parameter, resonance energy
Biotech Histochem. 2023 May 25:1-5. doi: 10.1080/10520295.2023.2215547. Online ahead of print.ABSTRACTDetermining the extent of conjugation in dyes and fluorochromes is a helpful tool for understanding or predicting the behavior of these compounds when used as stains for microscopy. One measure that has been used repeatedly is conjugated bond number (CBN), which is the number of bonds in a conjugated system. CBN can be obtained by inspection of the structure of a compound, but the rules for how to determine what constitutes a conjugated system are not fully established. Using molecular modeling software, we have defined mo...
Source: Biotechnic and Histochemistry - May 25, 2023 Category: Research Authors: Richard W Dapson Richard W Horobin Source Type: research
