Pravastatin attenuates isoprenaline induced cardiac fibrosis in a mouse model
Biotech Histochem. 2023 Oct 10:1-11. doi: 10.1080/10520295.2023.2260303. Online ahead of print.ABSTRACTWe investigated the effects of pravastatin (PRAVA) on isoprenaline (ISP) induced cardiac fibrosis using four groups of mice: untreated control, PRAVA, ISP, ISP + PRAVA groups. ISP, 20 mg/kg, was administered subcutaneously daily for 14 days. PRAVA, 20 mg/kg, was administered orally daily for 14 days. Mice were sacrificed on day15 and heart and blood samples were collected to investigate cardiac injury markers. The mean body weight for the ISP group on day 15 was decreased significantly compared to day 0; PRAVA increased t...
Source: Biotechnic and Histochemistry - October 10, 2023 Category: Research Authors: Abhinav Rana Thakur Uttam Singh Meemansha Sharma Manju Gari Tarun Kumar Subhashree Parida Madhu Cholenahalli Lingaraju Asok Kumar Mariappan Akhilesh Kumar Dinesh Kumar Source Type: research
Pravastatin attenuates isoprenaline induced cardiac fibrosis in a mouse model
Biotech Histochem. 2023 Oct 10:1-11. doi: 10.1080/10520295.2023.2260303. Online ahead of print.ABSTRACTWe investigated the effects of pravastatin (PRAVA) on isoprenaline (ISP) induced cardiac fibrosis using four groups of mice: untreated control, PRAVA, ISP, ISP + PRAVA groups. ISP, 20 mg/kg, was administered subcutaneously daily for 14 days. PRAVA, 20 mg/kg, was administered orally daily for 14 days. Mice were sacrificed on day15 and heart and blood samples were collected to investigate cardiac injury markers. The mean body weight for the ISP group on day 15 was decreased significantly compared to day 0; PRAVA increased t...
Source: Biotechnic and Histochemistry - October 10, 2023 Category: Research Authors: Abhinav Rana Thakur Uttam Singh Meemansha Sharma Manju Gari Tarun Kumar Subhashree Parida Madhu Cholenahalli Lingaraju Asok Kumar Mariappan Akhilesh Kumar Dinesh Kumar Source Type: research
Pravastatin attenuates isoprenaline induced cardiac fibrosis in a mouse model
Biotech Histochem. 2023 Oct 10:1-11. doi: 10.1080/10520295.2023.2260303. Online ahead of print.ABSTRACTWe investigated the effects of pravastatin (PRAVA) on isoprenaline (ISP) induced cardiac fibrosis using four groups of mice: untreated control, PRAVA, ISP, ISP + PRAVA groups. ISP, 20 mg/kg, was administered subcutaneously daily for 14 days. PRAVA, 20 mg/kg, was administered orally daily for 14 days. Mice were sacrificed on day15 and heart and blood samples were collected to investigate cardiac injury markers. The mean body weight for the ISP group on day 15 was decreased significantly compared to day 0; PRAVA increased t...
Source: Biotechnic and Histochemistry - October 10, 2023 Category: Research Authors: Abhinav Rana Thakur Uttam Singh Meemansha Sharma Manju Gari Tarun Kumar Subhashree Parida Madhu Cholenahalli Lingaraju Asok Kumar Mariappan Akhilesh Kumar Dinesh Kumar Source Type: research
Pravastatin attenuates isoprenaline induced cardiac fibrosis in a mouse model
Biotech Histochem. 2023 Oct 10:1-11. doi: 10.1080/10520295.2023.2260303. Online ahead of print.ABSTRACTWe investigated the effects of pravastatin (PRAVA) on isoprenaline (ISP) induced cardiac fibrosis using four groups of mice: untreated control, PRAVA, ISP, ISP + PRAVA groups. ISP, 20 mg/kg, was administered subcutaneously daily for 14 days. PRAVA, 20 mg/kg, was administered orally daily for 14 days. Mice were sacrificed on day15 and heart and blood samples were collected to investigate cardiac injury markers. The mean body weight for the ISP group on day 15 was decreased significantly compared to day 0; PRAVA increased t...
Source: Biotechnic and Histochemistry - October 10, 2023 Category: Research Authors: Abhinav Rana Thakur Uttam Singh Meemansha Sharma Manju Gari Tarun Kumar Subhashree Parida Madhu Cholenahalli Lingaraju Asok Kumar Mariappan Akhilesh Kumar Dinesh Kumar Source Type: research
Pravastatin attenuates isoprenaline induced cardiac fibrosis in a mouse model
Biotech Histochem. 2023 Oct 10:1-11. doi: 10.1080/10520295.2023.2260303. Online ahead of print.ABSTRACTWe investigated the effects of pravastatin (PRAVA) on isoprenaline (ISP) induced cardiac fibrosis using four groups of mice: untreated control, PRAVA, ISP, ISP + PRAVA groups. ISP, 20 mg/kg, was administered subcutaneously daily for 14 days. PRAVA, 20 mg/kg, was administered orally daily for 14 days. Mice were sacrificed on day15 and heart and blood samples were collected to investigate cardiac injury markers. The mean body weight for the ISP group on day 15 was decreased significantly compared to day 0; PRAVA increased t...
Source: Biotechnic and Histochemistry - October 10, 2023 Category: Research Authors: Abhinav Rana Thakur Uttam Singh Meemansha Sharma Manju Gari Tarun Kumar Subhashree Parida Madhu Cholenahalli Lingaraju Asok Kumar Mariappan Akhilesh Kumar Dinesh Kumar Source Type: research
Pravastatin attenuates isoprenaline induced cardiac fibrosis in a mouse model
Biotech Histochem. 2023 Oct 10:1-11. doi: 10.1080/10520295.2023.2260303. Online ahead of print.ABSTRACTWe investigated the effects of pravastatin (PRAVA) on isoprenaline (ISP) induced cardiac fibrosis using four groups of mice: untreated control, PRAVA, ISP, ISP + PRAVA groups. ISP, 20 mg/kg, was administered subcutaneously daily for 14 days. PRAVA, 20 mg/kg, was administered orally daily for 14 days. Mice were sacrificed on day15 and heart and blood samples were collected to investigate cardiac injury markers. The mean body weight for the ISP group on day 15 was decreased significantly compared to day 0; PRAVA increased t...
Source: Biotechnic and Histochemistry - October 10, 2023 Category: Research Authors: Abhinav Rana Thakur Uttam Singh Meemansha Sharma Manju Gari Tarun Kumar Subhashree Parida Madhu Cholenahalli Lingaraju Asok Kumar Mariappan Akhilesh Kumar Dinesh Kumar Source Type: research
Pravastatin attenuates isoprenaline induced cardiac fibrosis in a mouse model
Biotech Histochem. 2023 Oct 10:1-11. doi: 10.1080/10520295.2023.2260303. Online ahead of print.ABSTRACTWe investigated the effects of pravastatin (PRAVA) on isoprenaline (ISP) induced cardiac fibrosis using four groups of mice: untreated control, PRAVA, ISP, ISP + PRAVA groups. ISP, 20 mg/kg, was administered subcutaneously daily for 14 days. PRAVA, 20 mg/kg, was administered orally daily for 14 days. Mice were sacrificed on day15 and heart and blood samples were collected to investigate cardiac injury markers. The mean body weight for the ISP group on day 15 was decreased significantly compared to day 0; PRAVA increased t...
Source: Biotechnic and Histochemistry - October 10, 2023 Category: Research Authors: Abhinav Rana Thakur Uttam Singh Meemansha Sharma Manju Gari Tarun Kumar Subhashree Parida Madhu Cholenahalli Lingaraju Asok Kumar Mariappan Akhilesh Kumar Dinesh Kumar Source Type: research
Pravastatin attenuates isoprenaline induced cardiac fibrosis in a mouse model
Biotech Histochem. 2023 Oct 10:1-11. doi: 10.1080/10520295.2023.2260303. Online ahead of print.ABSTRACTWe investigated the effects of pravastatin (PRAVA) on isoprenaline (ISP) induced cardiac fibrosis using four groups of mice: untreated control, PRAVA, ISP, ISP + PRAVA groups. ISP, 20 mg/kg, was administered subcutaneously daily for 14 days. PRAVA, 20 mg/kg, was administered orally daily for 14 days. Mice were sacrificed on day15 and heart and blood samples were collected to investigate cardiac injury markers. The mean body weight for the ISP group on day 15 was decreased significantly compared to day 0; PRAVA increased t...
Source: Biotechnic and Histochemistry - October 10, 2023 Category: Research Authors: Abhinav Rana Thakur Uttam Singh Meemansha Sharma Manju Gari Tarun Kumar Subhashree Parida Madhu Cholenahalli Lingaraju Asok Kumar Mariappan Akhilesh Kumar Dinesh Kumar Source Type: research
Pravastatin attenuates isoprenaline induced cardiac fibrosis in a mouse model
Biotech Histochem. 2023 Oct 10:1-11. doi: 10.1080/10520295.2023.2260303. Online ahead of print.ABSTRACTWe investigated the effects of pravastatin (PRAVA) on isoprenaline (ISP) induced cardiac fibrosis using four groups of mice: untreated control, PRAVA, ISP, ISP + PRAVA groups. ISP, 20 mg/kg, was administered subcutaneously daily for 14 days. PRAVA, 20 mg/kg, was administered orally daily for 14 days. Mice were sacrificed on day15 and heart and blood samples were collected to investigate cardiac injury markers. The mean body weight for the ISP group on day 15 was decreased significantly compared to day 0; PRAVA increased t...
Source: Biotechnic and Histochemistry - October 10, 2023 Category: Research Authors: Abhinav Rana Thakur Uttam Singh Meemansha Sharma Manju Gari Tarun Kumar Subhashree Parida Madhu Cholenahalli Lingaraju Asok Kumar Mariappan Akhilesh Kumar Dinesh Kumar Source Type: research
Pravastatin attenuates isoprenaline induced cardiac fibrosis in a mouse model
Biotech Histochem. 2023 Oct 10:1-11. doi: 10.1080/10520295.2023.2260303. Online ahead of print.ABSTRACTWe investigated the effects of pravastatin (PRAVA) on isoprenaline (ISP) induced cardiac fibrosis using four groups of mice: untreated control, PRAVA, ISP, ISP + PRAVA groups. ISP, 20 mg/kg, was administered subcutaneously daily for 14 days. PRAVA, 20 mg/kg, was administered orally daily for 14 days. Mice were sacrificed on day15 and heart and blood samples were collected to investigate cardiac injury markers. The mean body weight for the ISP group on day 15 was decreased significantly compared to day 0; PRAVA increased t...
Source: Biotechnic and Histochemistry - October 10, 2023 Category: Research Authors: Abhinav Rana Thakur Uttam Singh Meemansha Sharma Manju Gari Tarun Kumar Subhashree Parida Madhu Cholenahalli Lingaraju Asok Kumar Mariappan Akhilesh Kumar Dinesh Kumar Source Type: research
Pravastatin attenuates isoprenaline induced cardiac fibrosis in a mouse model
Biotech Histochem. 2023 Oct 10:1-11. doi: 10.1080/10520295.2023.2260303. Online ahead of print.ABSTRACTWe investigated the effects of pravastatin (PRAVA) on isoprenaline (ISP) induced cardiac fibrosis using four groups of mice: untreated control, PRAVA, ISP, ISP + PRAVA groups. ISP, 20 mg/kg, was administered subcutaneously daily for 14 days. PRAVA, 20 mg/kg, was administered orally daily for 14 days. Mice were sacrificed on day15 and heart and blood samples were collected to investigate cardiac injury markers. The mean body weight for the ISP group on day 15 was decreased significantly compared to day 0; PRAVA increased t...
Source: Biotechnic and Histochemistry - October 10, 2023 Category: Research Authors: Abhinav Rana Thakur Uttam Singh Meemansha Sharma Manju Gari Tarun Kumar Subhashree Parida Madhu Cholenahalli Lingaraju Asok Kumar Mariappan Akhilesh Kumar Dinesh Kumar Source Type: research
Pravastatin attenuates isoprenaline induced cardiac fibrosis in a mouse model
Biotech Histochem. 2023 Oct 10:1-11. doi: 10.1080/10520295.2023.2260303. Online ahead of print.ABSTRACTWe investigated the effects of pravastatin (PRAVA) on isoprenaline (ISP) induced cardiac fibrosis using four groups of mice: untreated control, PRAVA, ISP, ISP + PRAVA groups. ISP, 20 mg/kg, was administered subcutaneously daily for 14 days. PRAVA, 20 mg/kg, was administered orally daily for 14 days. Mice were sacrificed on day15 and heart and blood samples were collected to investigate cardiac injury markers. The mean body weight for the ISP group on day 15 was decreased significantly compared to day 0; PRAVA increased t...
Source: Biotechnic and Histochemistry - October 10, 2023 Category: Research Authors: Abhinav Rana Thakur Uttam Singh Meemansha Sharma Manju Gari Tarun Kumar Subhashree Parida Madhu Cholenahalli Lingaraju Asok Kumar Mariappan Akhilesh Kumar Dinesh Kumar Source Type: research
Immunohistochemical evaluation of hormones secreted by pancreatic endocrine tumors
Biotech Histochem. 2023 Oct 3:1-6. doi: 10.1080/10520295.2023.2260307. Online ahead of print.ABSTRACTThe endocrine component of the pancreas is located primarily in the islets of Langerhans, but is also found as single cells among the acinar cells and duct epithelium. It currently is thought that endocrine tumors of the pancreas (PETs) arise from pluripotent stem cells located within the ductal epithelium rather than from existing endocrine cells. Islet cell components include alpha, beta, PP, delta and epsilon cells, which secrete glucagon, insulin, pancreatic polypeptide, somatostatin and ghrelin, respectively. We invest...
Source: Biotechnic and Histochemistry - October 3, 2023 Category: Research Authors: Anne Mones Sheila Criswell Source Type: research
Immunohistochemical evaluation of hormones secreted by pancreatic endocrine tumors
Biotech Histochem. 2023 Oct 3:1-6. doi: 10.1080/10520295.2023.2260307. Online ahead of print.ABSTRACTThe endocrine component of the pancreas is located primarily in the islets of Langerhans, but is also found as single cells among the acinar cells and duct epithelium. It currently is thought that endocrine tumors of the pancreas (PETs) arise from pluripotent stem cells located within the ductal epithelium rather than from existing endocrine cells. Islet cell components include alpha, beta, PP, delta and epsilon cells, which secrete glucagon, insulin, pancreatic polypeptide, somatostatin and ghrelin, respectively. We invest...
Source: Biotechnic and Histochemistry - October 3, 2023 Category: Research Authors: Anne Mones Sheila Criswell Source Type: research
Immunohistochemical evaluation of hormones secreted by pancreatic endocrine tumors
Biotech Histochem. 2023 Oct 3:1-6. doi: 10.1080/10520295.2023.2260307. Online ahead of print.ABSTRACTThe endocrine component of the pancreas is located primarily in the islets of Langerhans, but is also found as single cells among the acinar cells and duct epithelium. It currently is thought that endocrine tumors of the pancreas (PETs) arise from pluripotent stem cells located within the ductal epithelium rather than from existing endocrine cells. Islet cell components include alpha, beta, PP, delta and epsilon cells, which secrete glucagon, insulin, pancreatic polypeptide, somatostatin and ghrelin, respectively. We invest...
Source: Biotechnic and Histochemistry - October 3, 2023 Category: Research Authors: Anne Mones Sheila Criswell Source Type: research
