Selenium protection from DNA damage and regulation of apoptosis signaling following cyclophosphamide induced cardiotoxicity in rats
Biotech Histochem. 2023 Sep 11:1-9. doi: 10.1080/10520295.2023.2253424. Online ahead of print.ABSTRACTWe investigated the mechanism of the cardioprotective effect of selenium (Se) against cyclophosphamide (CPA) induced cardiotoxicity in rats. We divided 24 female Wistar albino rats into four groups. The control group was injected intraperitoneally (i.p.) with normal saline. The CPA group was injected i.p. with 200 mg/kg CPA. The Se group was injected i.p. with 1 mg/kg Se. The CPA + Se group was injected i.p. with 200 mg/kg CPA and 1 mg/kg Se. Rats were euthanized 24 h after injection and heart tissues were harvested. Histo...
Source: Biotechnic and Histochemistry - September 11, 2023 Category: Research Authors: Emrah İpek Mehmet Hesap çıoğlu Mehmet Karabo ğa Hamdi Avc ı Source Type: research
Selenium protection from DNA damage and regulation of apoptosis signaling following cyclophosphamide induced cardiotoxicity in rats
Biotech Histochem. 2023 Sep 11:1-9. doi: 10.1080/10520295.2023.2253424. Online ahead of print.ABSTRACTWe investigated the mechanism of the cardioprotective effect of selenium (Se) against cyclophosphamide (CPA) induced cardiotoxicity in rats. We divided 24 female Wistar albino rats into four groups. The control group was injected intraperitoneally (i.p.) with normal saline. The CPA group was injected i.p. with 200 mg/kg CPA. The Se group was injected i.p. with 1 mg/kg Se. The CPA + Se group was injected i.p. with 200 mg/kg CPA and 1 mg/kg Se. Rats were euthanized 24 h after injection and heart tissues were harvested. Histo...
Source: Biotechnic and Histochemistry - September 11, 2023 Category: Research Authors: Emrah İpek Mehmet Hesap çıoğlu Mehmet Karabo ğa Hamdi Avc ı Source Type: research
Selenium protection from DNA damage and regulation of apoptosis signaling following cyclophosphamide induced cardiotoxicity in rats
Biotech Histochem. 2023 Sep 11:1-9. doi: 10.1080/10520295.2023.2253424. Online ahead of print.ABSTRACTWe investigated the mechanism of the cardioprotective effect of selenium (Se) against cyclophosphamide (CPA) induced cardiotoxicity in rats. We divided 24 female Wistar albino rats into four groups. The control group was injected intraperitoneally (i.p.) with normal saline. The CPA group was injected i.p. with 200 mg/kg CPA. The Se group was injected i.p. with 1 mg/kg Se. The CPA + Se group was injected i.p. with 200 mg/kg CPA and 1 mg/kg Se. Rats were euthanized 24 h after injection and heart tissues were harvested. Histo...
Source: Biotechnic and Histochemistry - September 11, 2023 Category: Research Authors: Emrah İpek Mehmet Hesap çıoğlu Mehmet Karabo ğa Hamdi Avc ı Source Type: research
Selenium protection from DNA damage and regulation of apoptosis signaling following cyclophosphamide induced cardiotoxicity in rats
Biotech Histochem. 2023 Sep 11:1-9. doi: 10.1080/10520295.2023.2253424. Online ahead of print.ABSTRACTWe investigated the mechanism of the cardioprotective effect of selenium (Se) against cyclophosphamide (CPA) induced cardiotoxicity in rats. We divided 24 female Wistar albino rats into four groups. The control group was injected intraperitoneally (i.p.) with normal saline. The CPA group was injected i.p. with 200 mg/kg CPA. The Se group was injected i.p. with 1 mg/kg Se. The CPA + Se group was injected i.p. with 200 mg/kg CPA and 1 mg/kg Se. Rats were euthanized 24 h after injection and heart tissues were harvested. Histo...
Source: Biotechnic and Histochemistry - September 11, 2023 Category: Research Authors: Emrah İpek Mehmet Hesap çıoğlu Mehmet Karabo ğa Hamdi Avc ı Source Type: research
Selenium protection from DNA damage and regulation of apoptosis signaling following cyclophosphamide induced cardiotoxicity in rats
Biotech Histochem. 2023 Sep 11:1-9. doi: 10.1080/10520295.2023.2253424. Online ahead of print.ABSTRACTWe investigated the mechanism of the cardioprotective effect of selenium (Se) against cyclophosphamide (CPA) induced cardiotoxicity in rats. We divided 24 female Wistar albino rats into four groups. The control group was injected intraperitoneally (i.p.) with normal saline. The CPA group was injected i.p. with 200 mg/kg CPA. The Se group was injected i.p. with 1 mg/kg Se. The CPA + Se group was injected i.p. with 200 mg/kg CPA and 1 mg/kg Se. Rats were euthanized 24 h after injection and heart tissues were harvested. Histo...
Source: Biotechnic and Histochemistry - September 11, 2023 Category: Research Authors: Emrah İpek Mehmet Hesap çıoğlu Mehmet Karabo ğa Hamdi Avc ı Source Type: research
Selenium protection from DNA damage and regulation of apoptosis signaling following cyclophosphamide induced cardiotoxicity in rats
Biotech Histochem. 2023 Sep 11:1-9. doi: 10.1080/10520295.2023.2253424. Online ahead of print.ABSTRACTWe investigated the mechanism of the cardioprotective effect of selenium (Se) against cyclophosphamide (CPA) induced cardiotoxicity in rats. We divided 24 female Wistar albino rats into four groups. The control group was injected intraperitoneally (i.p.) with normal saline. The CPA group was injected i.p. with 200 mg/kg CPA. The Se group was injected i.p. with 1 mg/kg Se. The CPA + Se group was injected i.p. with 200 mg/kg CPA and 1 mg/kg Se. Rats were euthanized 24 h after injection and heart tissues were harvested. Histo...
Source: Biotechnic and Histochemistry - September 11, 2023 Category: Research Authors: Emrah İpek Mehmet Hesap çıoğlu Mehmet Karabo ğa Hamdi Avc ı Source Type: research
Selenium protection from DNA damage and regulation of apoptosis signaling following cyclophosphamide induced cardiotoxicity in rats
Biotech Histochem. 2023 Sep 11:1-9. doi: 10.1080/10520295.2023.2253424. Online ahead of print.ABSTRACTWe investigated the mechanism of the cardioprotective effect of selenium (Se) against cyclophosphamide (CPA) induced cardiotoxicity in rats. We divided 24 female Wistar albino rats into four groups. The control group was injected intraperitoneally (i.p.) with normal saline. The CPA group was injected i.p. with 200 mg/kg CPA. The Se group was injected i.p. with 1 mg/kg Se. The CPA + Se group was injected i.p. with 200 mg/kg CPA and 1 mg/kg Se. Rats were euthanized 24 h after injection and heart tissues were harvested. Histo...
Source: Biotechnic and Histochemistry - September 11, 2023 Category: Research Authors: Emrah İpek Mehmet Hesap çıoğlu Mehmet Karabo ğa Hamdi Avc ı Source Type: research
Selenium protection from DNA damage and regulation of apoptosis signaling following cyclophosphamide induced cardiotoxicity in rats
Biotech Histochem. 2023 Sep 11:1-9. doi: 10.1080/10520295.2023.2253424. Online ahead of print.ABSTRACTWe investigated the mechanism of the cardioprotective effect of selenium (Se) against cyclophosphamide (CPA) induced cardiotoxicity in rats. We divided 24 female Wistar albino rats into four groups. The control group was injected intraperitoneally (i.p.) with normal saline. The CPA group was injected i.p. with 200 mg/kg CPA. The Se group was injected i.p. with 1 mg/kg Se. The CPA + Se group was injected i.p. with 200 mg/kg CPA and 1 mg/kg Se. Rats were euthanized 24 h after injection and heart tissues were harvested. Histo...
Source: Biotechnic and Histochemistry - September 11, 2023 Category: Research Authors: Emrah İpek Mehmet Hesap çıoğlu Mehmet Karabo ğa Hamdi Avc ı Source Type: research
Selenium protection from DNA damage and regulation of apoptosis signaling following cyclophosphamide induced cardiotoxicity in rats
Biotech Histochem. 2023 Sep 11:1-9. doi: 10.1080/10520295.2023.2253424. Online ahead of print.ABSTRACTWe investigated the mechanism of the cardioprotective effect of selenium (Se) against cyclophosphamide (CPA) induced cardiotoxicity in rats. We divided 24 female Wistar albino rats into four groups. The control group was injected intraperitoneally (i.p.) with normal saline. The CPA group was injected i.p. with 200 mg/kg CPA. The Se group was injected i.p. with 1 mg/kg Se. The CPA + Se group was injected i.p. with 200 mg/kg CPA and 1 mg/kg Se. Rats were euthanized 24 h after injection and heart tissues were harvested. Histo...
Source: Biotechnic and Histochemistry - September 11, 2023 Category: Research Authors: Emrah İpek Mehmet Hesap çıoğlu Mehmet Karabo ğa Hamdi Avc ı Source Type: research
Effects of adriamycin on cell differentiation and proliferation in rat testis
Biotech Histochem. 2023 Sep 1:1-11. doi: 10.1080/10520295.2023.2248880. Online ahead of print.ABSTRACTAlthough adriamycin (ADR) is used to treat many cancers, it can be toxic to healthy organs including the testis. We investigated the effects of ADR on pluripotency in rat testis. Testicular damage was induced by either cumulative or single dose single dose administration of ADR in Wistar albino rats. Rats were divided randomly into three groups: untreated control, cumulative dose ADR group (2 mg/kg ADR every three days for 30 days) and single dose ADR group (15 mg/kg, single dose ADR). Testicular damage was evaluated and s...
Source: Biotechnic and Histochemistry - September 1, 2023 Category: Research Authors: Ali Tugrul Akin Ayse Toluk Saim Ozdamar Serpil Taheri Emin Kaymak Ecmel Mehmetbeyoglu Source Type: research
Effects of adriamycin on cell differentiation and proliferation in rat testis
Biotech Histochem. 2023 Sep 1:1-11. doi: 10.1080/10520295.2023.2248880. Online ahead of print.ABSTRACTAlthough adriamycin (ADR) is used to treat many cancers, it can be toxic to healthy organs including the testis. We investigated the effects of ADR on pluripotency in rat testis. Testicular damage was induced by either cumulative or single dose single dose administration of ADR in Wistar albino rats. Rats were divided randomly into three groups: untreated control, cumulative dose ADR group (2 mg/kg ADR every three days for 30 days) and single dose ADR group (15 mg/kg, single dose ADR). Testicular damage was evaluated and s...
Source: Biotechnic and Histochemistry - September 1, 2023 Category: Research Authors: Ali Tugrul Akin Ayse Toluk Saim Ozdamar Serpil Taheri Emin Kaymak Ecmel Mehmetbeyoglu Source Type: research
Effects of adriamycin on cell differentiation and proliferation in rat testis
Biotech Histochem. 2023 Sep 1:1-11. doi: 10.1080/10520295.2023.2248880. Online ahead of print.ABSTRACTAlthough adriamycin (ADR) is used to treat many cancers, it can be toxic to healthy organs including the testis. We investigated the effects of ADR on pluripotency in rat testis. Testicular damage was induced by either cumulative or single dose single dose administration of ADR in Wistar albino rats. Rats were divided randomly into three groups: untreated control, cumulative dose ADR group (2 mg/kg ADR every three days for 30 days) and single dose ADR group (15 mg/kg, single dose ADR). Testicular damage was evaluated and s...
Source: Biotechnic and Histochemistry - September 1, 2023 Category: Research Authors: Ali Tugrul Akin Ayse Toluk Saim Ozdamar Serpil Taheri Emin Kaymak Ecmel Mehmetbeyoglu Source Type: research
Effects of adriamycin on cell differentiation and proliferation in rat testis
Biotech Histochem. 2023 Sep 1:1-11. doi: 10.1080/10520295.2023.2248880. Online ahead of print.ABSTRACTAlthough adriamycin (ADR) is used to treat many cancers, it can be toxic to healthy organs including the testis. We investigated the effects of ADR on pluripotency in rat testis. Testicular damage was induced by either cumulative or single dose single dose administration of ADR in Wistar albino rats. Rats were divided randomly into three groups: untreated control, cumulative dose ADR group (2 mg/kg ADR every three days for 30 days) and single dose ADR group (15 mg/kg, single dose ADR). Testicular damage was evaluated and s...
Source: Biotechnic and Histochemistry - September 1, 2023 Category: Research Authors: Ali Tugrul Akin Ayse Toluk Saim Ozdamar Serpil Taheri Emin Kaymak Ecmel Mehmetbeyoglu Source Type: research
Effects of adriamycin on cell differentiation and proliferation in rat testis
Biotech Histochem. 2023 Sep 1:1-11. doi: 10.1080/10520295.2023.2248880. Online ahead of print.ABSTRACTAlthough adriamycin (ADR) is used to treat many cancers, it can be toxic to healthy organs including the testis. We investigated the effects of ADR on pluripotency in rat testis. Testicular damage was induced by either cumulative or single dose single dose administration of ADR in Wistar albino rats. Rats were divided randomly into three groups: untreated control, cumulative dose ADR group (2 mg/kg ADR every three days for 30 days) and single dose ADR group (15 mg/kg, single dose ADR). Testicular damage was evaluated and s...
Source: Biotechnic and Histochemistry - September 1, 2023 Category: Research Authors: Ali Tugrul Akin Ayse Toluk Saim Ozdamar Serpil Taheri Emin Kaymak Ecmel Mehmetbeyoglu Source Type: research
Effects of adriamycin on cell differentiation and proliferation in rat testis
Biotech Histochem. 2023 Sep 1:1-11. doi: 10.1080/10520295.2023.2248880. Online ahead of print.ABSTRACTAlthough adriamycin (ADR) is used to treat many cancers, it can be toxic to healthy organs including the testis. We investigated the effects of ADR on pluripotency in rat testis. Testicular damage was induced by either cumulative or single dose single dose administration of ADR in Wistar albino rats. Rats were divided randomly into three groups: untreated control, cumulative dose ADR group (2 mg/kg ADR every three days for 30 days) and single dose ADR group (15 mg/kg, single dose ADR). Testicular damage was evaluated and s...
Source: Biotechnic and Histochemistry - September 1, 2023 Category: Research Authors: Ali Tugrul Akin Ayse Toluk Saim Ozdamar Serpil Taheri Emin Kaymak Ecmel Mehmetbeyoglu Source Type: research
