Modeling the extent of conjugation in histochemical dyes and fluorescent probes: clarification in calculating conjugated bond number (CBN) and introduction of a new parameter, resonance energy
Biotech Histochem. 2023 May 25:1-5. doi: 10.1080/10520295.2023.2215547. Online ahead of print.ABSTRACTDetermining the extent of conjugation in dyes and fluorochromes is a helpful tool for understanding or predicting the behavior of these compounds when used as stains for microscopy. One measure that has been used repeatedly is conjugated bond number (CBN), which is the number of bonds in a conjugated system. CBN can be obtained by inspection of the structure of a compound, but the rules for how to determine what constitutes a conjugated system are not fully established. Using molecular modeling software, we have defined mo...
Source: Biotechnic and Histochemistry - May 25, 2023 Category: Research Authors: Richard W Dapson Richard W Horobin Source Type: research
Modeling the extent of conjugation in histochemical dyes and fluorescent probes: clarification in calculating conjugated bond number (CBN) and introduction of a new parameter, resonance energy
Biotech Histochem. 2023 May 25:1-5. doi: 10.1080/10520295.2023.2215547. Online ahead of print.ABSTRACTDetermining the extent of conjugation in dyes and fluorochromes is a helpful tool for understanding or predicting the behavior of these compounds when used as stains for microscopy. One measure that has been used repeatedly is conjugated bond number (CBN), which is the number of bonds in a conjugated system. CBN can be obtained by inspection of the structure of a compound, but the rules for how to determine what constitutes a conjugated system are not fully established. Using molecular modeling software, we have defined mo...
Source: Biotechnic and Histochemistry - May 25, 2023 Category: Research Authors: Richard W Dapson Richard W Horobin Source Type: research
Modeling the extent of conjugation in histochemical dyes and fluorescent probes: clarification in calculating conjugated bond number (CBN) and introduction of a new parameter, resonance energy
Biotech Histochem. 2023 May 25:1-5. doi: 10.1080/10520295.2023.2215547. Online ahead of print.ABSTRACTDetermining the extent of conjugation in dyes and fluorochromes is a helpful tool for understanding or predicting the behavior of these compounds when used as stains for microscopy. One measure that has been used repeatedly is conjugated bond number (CBN), which is the number of bonds in a conjugated system. CBN can be obtained by inspection of the structure of a compound, but the rules for how to determine what constitutes a conjugated system are not fully established. Using molecular modeling software, we have defined mo...
Source: Biotechnic and Histochemistry - May 25, 2023 Category: Research Authors: Richard W Dapson Richard W Horobin Source Type: research
Modeling the extent of conjugation in histochemical dyes and fluorescent probes: clarification in calculating conjugated bond number (CBN) and introduction of a new parameter, resonance energy
Biotech Histochem. 2023 May 25:1-5. doi: 10.1080/10520295.2023.2215547. Online ahead of print.ABSTRACTDetermining the extent of conjugation in dyes and fluorochromes is a helpful tool for understanding or predicting the behavior of these compounds when used as stains for microscopy. One measure that has been used repeatedly is conjugated bond number (CBN), which is the number of bonds in a conjugated system. CBN can be obtained by inspection of the structure of a compound, but the rules for how to determine what constitutes a conjugated system are not fully established. Using molecular modeling software, we have defined mo...
Source: Biotechnic and Histochemistry - May 25, 2023 Category: Research Authors: Richard W Dapson Richard W Horobin Source Type: research
Evaluation of DNA damage in obese children using the chromatin dispersion test
Biotech Histochem. 2023 May 23:1-5. doi: 10.1080/10520295.2023.2210848. Online ahead of print.ABSTRACTChildhood obesity predicts adult obesity and may increase the lifetime risk of adverse health outcomes. Obesity is characterized by oxidative stress that can induce DNA damage; however, studies of childhood and adolescent obesity are scarce. We investigated DNA damage due to obesity in Mexican children using the chromatin dispersion test (CDT). We evaluated DNA damage to peripheral lymphocytes of 32 children grouped according to body mass index as normal weight (controls), overweight and obese groups using guidelines from ...
Source: Biotechnic and Histochemistry - May 23, 2023 Category: Research Authors: Martha I D ávila-Rodríguez Francisco Gonz ález-Salazar Manuel L ópez-Cabanillas Ricardo M Cerda-Flores Elva I Cort és-Gutiérrez Source Type: research
Evaluation of DNA damage in obese children using the chromatin dispersion test
Biotech Histochem. 2023 May 23:1-5. doi: 10.1080/10520295.2023.2210848. Online ahead of print.ABSTRACTChildhood obesity predicts adult obesity and may increase the lifetime risk of adverse health outcomes. Obesity is characterized by oxidative stress that can induce DNA damage; however, studies of childhood and adolescent obesity are scarce. We investigated DNA damage due to obesity in Mexican children using the chromatin dispersion test (CDT). We evaluated DNA damage to peripheral lymphocytes of 32 children grouped according to body mass index as normal weight (controls), overweight and obese groups using guidelines from ...
Source: Biotechnic and Histochemistry - May 23, 2023 Category: Research Authors: Martha I D ávila-Rodríguez Francisco Gonz ález-Salazar Manuel L ópez-Cabanillas Ricardo M Cerda-Flores Elva I Cort és-Gutiérrez Source Type: research
Evaluation of DNA damage in obese children using the chromatin dispersion test
Biotech Histochem. 2023 May 23:1-5. doi: 10.1080/10520295.2023.2210848. Online ahead of print.ABSTRACTChildhood obesity predicts adult obesity and may increase the lifetime risk of adverse health outcomes. Obesity is characterized by oxidative stress that can induce DNA damage; however, studies of childhood and adolescent obesity are scarce. We investigated DNA damage due to obesity in Mexican children using the chromatin dispersion test (CDT). We evaluated DNA damage to peripheral lymphocytes of 32 children grouped according to body mass index as normal weight (controls), overweight and obese groups using guidelines from ...
Source: Biotechnic and Histochemistry - May 23, 2023 Category: Research Authors: Martha I D ávila-Rodríguez Francisco Gonz ález-Salazar Manuel L ópez-Cabanillas Ricardo M Cerda-Flores Elva I Cort és-Gutiérrez Source Type: research
Role of p38 MAPK, Akt and NF κB in renoprotective effects of nebivolol on renal ischemia-reperfusion injury in rats
Biotech Histochem. 2023 May 22:1-11. doi: 10.1080/10520295.2023.2212412. Online ahead of print.ABSTRACTRenal ischemia-reperfusion (I-R) injury is a complex pathophysiologic condition characterized by oxidative stress, inflammation and apoptosis. We investigated the potential renoprotective effect of nebivolol, a β1 adrenergic receptor blocker, against renal I-R injury. We focused on the role of nebivolol in activating p38 mitogen-activated protein kinase (MAPK) signaling, Akt (protein kinase B) and nuclear factor-κB (NFκB) transcription factors, which contribute to oxidative stress, inflammation and apoptosis during ren...
Source: Biotechnic and Histochemistry - May 22, 2023 Category: Research Authors: Zahide Cavdar Ayse Kocak Cemre Ural Aysan Afagh Sibel Ersan Seda Ozbal Merve Tatli Asli Celik Sevki Arslan Caner Cavdar Source Type: research
Role of p38 MAPK, Akt and NF κB in renoprotective effects of nebivolol on renal ischemia-reperfusion injury in rats
Biotech Histochem. 2023 May 22:1-11. doi: 10.1080/10520295.2023.2212412. Online ahead of print.ABSTRACTRenal ischemia-reperfusion (I-R) injury is a complex pathophysiologic condition characterized by oxidative stress, inflammation and apoptosis. We investigated the potential renoprotective effect of nebivolol, a β1 adrenergic receptor blocker, against renal I-R injury. We focused on the role of nebivolol in activating p38 mitogen-activated protein kinase (MAPK) signaling, Akt (protein kinase B) and nuclear factor-κB (NFκB) transcription factors, which contribute to oxidative stress, inflammation and apoptosis during ren...
Source: Biotechnic and Histochemistry - May 22, 2023 Category: Research Authors: Zahide Cavdar Ayse Kocak Cemre Ural Aysan Afagh Sibel Ersan Seda Ozbal Merve Tatli Asli Celik Sevki Arslan Caner Cavdar Source Type: research
< em > Inula viscosa < /em > ameliorates acetic acid induced ulcerative colitis in rats
Biotech Histochem. 2023 May;98(4):255-266. doi: 10.1080/10520295.2023.2176923. Epub 2023 Feb 22.ABSTRACTIncreased pro-inflammatory cytokines and oxidative stress contribute to the pathophysiology of ulcerative colitis (UC). Inula viscosa is a plant with antioxidant and anti-inflammatory properties. We investigated the effect of an ethanolic extract of I. viscosa on an experimental UC model created using acetic acid. Rats were divided into four groups of eight: group 1, control; group 2, 3% acetic acid group; group 3, 100 mg/kg sulfasalazine + 3% acetic acid group; group 4, 400 mg/kg I. viscosa + 3% acetic acid. I. viscosa ...
Source: Biotechnic and Histochemistry - May 11, 2023 Category: Research Authors: Mustafa Cellat İbrahim Ozan Tekeli Erdin ç Türk Tuba Aydin Ahmet Uyar Cafer Tayer İşler İshak Gökçek Muhammed Etyemez Mehmet G üvenç Source Type: research
Seed coating with micronutrients improves germination, growth, yield and microelement nutrients of maize ( < em > Zea mays < /em > L.)
Biotech Histochem. 2023 May;98(4):230-242. doi: 10.1080/10520295.2023.2174273. Epub 2023 Feb 22.ABSTRACTSoil and foliar application are the most widely used methods for adding micronutrients to maize. High quality micronutrient fertilizers, however, are difficult to obtain in developing countries; micronutrient seed coatings are an attractive and practical alternative. We applied this approach to maize (Zea mays L.) to demonstrate the effects of boron (B), iron (Fe), manganese (Mn), molybdenum (Mo) and zinc (Zn) sulfates on maize germination, vigor, seedling growth, seed yield and seed quality as well as on seed microeleme...
Source: Biotechnic and Histochemistry - May 11, 2023 Category: Research Authors: Fa-Bo Chen Yun-Chao Feng Shi-Ping Huo Source Type: research
< em > Inula viscosa < /em > ameliorates acetic acid induced ulcerative colitis in rats
Biotech Histochem. 2023 May;98(4):255-266. doi: 10.1080/10520295.2023.2176923. Epub 2023 Feb 22.ABSTRACTIncreased pro-inflammatory cytokines and oxidative stress contribute to the pathophysiology of ulcerative colitis (UC). Inula viscosa is a plant with antioxidant and anti-inflammatory properties. We investigated the effect of an ethanolic extract of I. viscosa on an experimental UC model created using acetic acid. Rats were divided into four groups of eight: group 1, control; group 2, 3% acetic acid group; group 3, 100 mg/kg sulfasalazine + 3% acetic acid group; group 4, 400 mg/kg I. viscosa + 3% acetic acid. I. viscosa ...
Source: Biotechnic and Histochemistry - May 11, 2023 Category: Research Authors: Mustafa Cellat İbrahim Ozan Tekeli Erdin ç Türk Tuba Aydin Ahmet Uyar Cafer Tayer İşler İshak Gökçek Muhammed Etyemez Mehmet G üvenç Source Type: research
Seed coating with micronutrients improves germination, growth, yield and microelement nutrients of maize ( < em > Zea mays < /em > L.)
Biotech Histochem. 2023 May;98(4):230-242. doi: 10.1080/10520295.2023.2174273. Epub 2023 Feb 22.ABSTRACTSoil and foliar application are the most widely used methods for adding micronutrients to maize. High quality micronutrient fertilizers, however, are difficult to obtain in developing countries; micronutrient seed coatings are an attractive and practical alternative. We applied this approach to maize (Zea mays L.) to demonstrate the effects of boron (B), iron (Fe), manganese (Mn), molybdenum (Mo) and zinc (Zn) sulfates on maize germination, vigor, seedling growth, seed yield and seed quality as well as on seed microeleme...
Source: Biotechnic and Histochemistry - May 11, 2023 Category: Research Authors: Fa-Bo Chen Yun-Chao Feng Shi-Ping Huo Source Type: research
< em > Inula viscosa < /em > ameliorates acetic acid induced ulcerative colitis in rats
Biotech Histochem. 2023 May;98(4):255-266. doi: 10.1080/10520295.2023.2176923. Epub 2023 Feb 22.ABSTRACTIncreased pro-inflammatory cytokines and oxidative stress contribute to the pathophysiology of ulcerative colitis (UC). Inula viscosa is a plant with antioxidant and anti-inflammatory properties. We investigated the effect of an ethanolic extract of I. viscosa on an experimental UC model created using acetic acid. Rats were divided into four groups of eight: group 1, control; group 2, 3% acetic acid group; group 3, 100 mg/kg sulfasalazine + 3% acetic acid group; group 4, 400 mg/kg I. viscosa + 3% acetic acid. I. viscosa ...
Source: Biotechnic and Histochemistry - May 11, 2023 Category: Research Authors: Mustafa Cellat İbrahim Ozan Tekeli Erdin ç Türk Tuba Aydin Ahmet Uyar Cafer Tayer İşler İshak Gökçek Muhammed Etyemez Mehmet G üvenç Source Type: research
Seed coating with micronutrients improves germination, growth, yield and microelement nutrients of maize ( < em > Zea mays < /em > L.)
Biotech Histochem. 2023 May;98(4):230-242. doi: 10.1080/10520295.2023.2174273. Epub 2023 Feb 22.ABSTRACTSoil and foliar application are the most widely used methods for adding micronutrients to maize. High quality micronutrient fertilizers, however, are difficult to obtain in developing countries; micronutrient seed coatings are an attractive and practical alternative. We applied this approach to maize (Zea mays L.) to demonstrate the effects of boron (B), iron (Fe), manganese (Mn), molybdenum (Mo) and zinc (Zn) sulfates on maize germination, vigor, seedling growth, seed yield and seed quality as well as on seed microeleme...
Source: Biotechnic and Histochemistry - May 11, 2023 Category: Research Authors: Fa-Bo Chen Yun-Chao Feng Shi-Ping Huo Source Type: research
