Identification of exosome protein panels as predictive biomarkers for non-small cell lung cancer
CONCLUSIONS: These findings underscore the potential of plasma exosomal biomarkers for early NSCLC diagnosis and metastasis prediction. Notably, CFHR5 stands out as a promising prognostic indicator for NSCLC patients. The clinical utility of exosomal biomarkers offers the potential to enhance the management of NSCLC.PMID:37953280 | DOI:10.1186/s12575-023-00223-0 (Source: Biological Procedures Online)
Source: Biological Procedures Online - November 12, 2023 Category: Molecular Biology Authors: Bin Luo Zujun Que Xinyi Lu Dan Qi Zhi Qiao Yun Yang Fangfang Qian Yi Jiang Yan Li Ronghu Ke Xiaoyun Shen Hua Xiao Hegen Li Erxi Wu Jianhui Tian Source Type: research
Extracellular Vesicles for Drug Delivery in Cancer Treatment
Biol Proced Online. 2023 Nov 9;25(1):28. doi: 10.1186/s12575-023-00220-3.ABSTRACTExtracellular vesicles (EVs) are nanoscale vesicles derived from cells that mediate intercellular communication by transporting bioactive molecules. They play significant roles in various physiological and pathological conditions. EVs hold great potential as novel biomarkers of diseases, therapeutic agents, and drug delivery vehicles. Furthermore, EVs as novel drug delivery vehicles have demonstrated significant advantages in preclinical settings. In this review, we discussed the biogenesis and characteristics of EVs and their functions in can...
Source: Biological Procedures Online - November 10, 2023 Category: Molecular Biology Authors: Li Wang Xin Yu Juan Zhou Chunxia Su Source Type: research
Extracellular Vesicles for Drug Delivery in Cancer Treatment
Biol Proced Online. 2023 Nov 9;25(1):28. doi: 10.1186/s12575-023-00220-3.ABSTRACTExtracellular vesicles (EVs) are nanoscale vesicles derived from cells that mediate intercellular communication by transporting bioactive molecules. They play significant roles in various physiological and pathological conditions. EVs hold great potential as novel biomarkers of diseases, therapeutic agents, and drug delivery vehicles. Furthermore, EVs as novel drug delivery vehicles have demonstrated significant advantages in preclinical settings. In this review, we discussed the biogenesis and characteristics of EVs and their functions in can...
Source: Biological Procedures Online - November 10, 2023 Category: Molecular Biology Authors: Li Wang Xin Yu Juan Zhou Chunxia Su Source Type: research
Extracellular Vesicles for Drug Delivery in Cancer Treatment
Biol Proced Online. 2023 Nov 9;25(1):28. doi: 10.1186/s12575-023-00220-3.ABSTRACTExtracellular vesicles (EVs) are nanoscale vesicles derived from cells that mediate intercellular communication by transporting bioactive molecules. They play significant roles in various physiological and pathological conditions. EVs hold great potential as novel biomarkers of diseases, therapeutic agents, and drug delivery vehicles. Furthermore, EVs as novel drug delivery vehicles have demonstrated significant advantages in preclinical settings. In this review, we discussed the biogenesis and characteristics of EVs and their functions in can...
Source: Biological Procedures Online - November 10, 2023 Category: Molecular Biology Authors: Li Wang Xin Yu Juan Zhou Chunxia Su Source Type: research
Visualisation of Bluetongue Virus in the Salivary Apparatus of Culicoides Biting Midges Highlights the Accessory Glands as a Primary Arboviral Infection Site
CONCLUSIONS: Our work has revealed a novel site of virus-vector interactions, and a novel role of the accessory glands of Culicoides in arbovirus amplification and transmission. Our approach would also be applicable to a wide range of arbovirus vector groups including sand flies (Diptera: Psychodidae), as well as provide a powerful tool to investigate arbovirus infection and dissemination, particularly where there are practical challenges in the visualization of small size and delicate tissues of arthropods.PMID:37932658 | PMC:PMC10626815 | DOI:10.1186/s12575-023-00221-2 (Source: Biological Procedures Online)
Source: Biological Procedures Online - November 6, 2023 Category: Molecular Biology Authors: Marc Guimer à Busquets Faye V Brown Simon T Carpenter Karin E Darpel Christopher J Sanders Source Type: research
Visualisation of Bluetongue Virus in the Salivary Apparatus of Culicoides Biting Midges Highlights the Accessory Glands as a Primary Arboviral Infection Site
CONCLUSIONS: Our work has revealed a novel site of virus-vector interactions, and a novel role of the accessory glands of Culicoides in arbovirus amplification and transmission. Our approach would also be applicable to a wide range of arbovirus vector groups including sand flies (Diptera: Psychodidae), as well as provide a powerful tool to investigate arbovirus infection and dissemination, particularly where there are practical challenges in the visualization of small size and delicate tissues of arthropods.PMID:37932658 | PMC:PMC10626815 | DOI:10.1186/s12575-023-00221-2 (Source: Biological Procedures Online)
Source: Biological Procedures Online - November 6, 2023 Category: Molecular Biology Authors: Marc Guimer à Busquets Faye V Brown Simon T Carpenter Karin E Darpel Christopher J Sanders Source Type: research
Visualisation of Bluetongue Virus in the Salivary Apparatus of Culicoides Biting Midges Highlights the Accessory Glands as a Primary Arboviral Infection Site
CONCLUSIONS: Our work has revealed a novel site of virus-vector interactions, and a novel role of the accessory glands of Culicoides in arbovirus amplification and transmission. Our approach would also be applicable to a wide range of arbovirus vector groups including sand flies (Diptera: Psychodidae), as well as provide a powerful tool to investigate arbovirus infection and dissemination, particularly where there are practical challenges in the visualization of small size and delicate tissues of arthropods.PMID:37932658 | DOI:10.1186/s12575-023-00221-2 (Source: Biological Procedures Online)
Source: Biological Procedures Online - November 6, 2023 Category: Molecular Biology Authors: Marc Guimer à Busquets Faye V Brown Simon T Carpenter Karin E Darpel Christopher J Sanders Source Type: research
Comparison of two protocols for the generation of iPSC-derived human astrocytes
CONCLUSIONS: Overall, our analyses highlight the need to consider the advantages and disadvantages of a given differentiation protocol, when designing functional or drug discovery studies involving iPSC-derived astrocytes.PMID:37730545 | PMC:PMC10512486 | DOI:10.1186/s12575-023-00218-x (Source: Biological Procedures Online)
Source: Biological Procedures Online - September 20, 2023 Category: Molecular Biology Authors: Patrycja Mulica Carmen Venegas Zied Landoulsi Katja Badanjak Sylvie Delcambre Maria Tziortziou Soraya Hezzaz Jenny Ghelfi Semra Smajic Jens Schwamborn Rejko Kr üger Paul Antony Patrick May Enrico Glaab Anne Gr ünewald Sandro L Pereira Source Type: research
Comparison of two protocols for the generation of iPSC-derived human astrocytes
CONCLUSIONS: Overall, our analyses highlight the need to consider the advantages and disadvantages of a given differentiation protocol, when designing functional or drug discovery studies involving iPSC-derived astrocytes.PMID:37730545 | PMC:PMC10512486 | DOI:10.1186/s12575-023-00218-x (Source: Biological Procedures Online)
Source: Biological Procedures Online - September 20, 2023 Category: Molecular Biology Authors: Patrycja Mulica Carmen Venegas Zied Landoulsi Katja Badanjak Sylvie Delcambre Maria Tziortziou Soraya Hezzaz Jenny Ghelfi Semra Smajic Jens Schwamborn Rejko Kr üger Paul Antony Patrick May Enrico Glaab Anne Gr ünewald Sandro L Pereira Source Type: research
Comparison of two protocols for the generation of iPSC-derived human astrocytes
CONCLUSIONS: Overall, our analyses highlight the need to consider the advantages and disadvantages of a given differentiation protocol, when designing functional or drug discovery studies involving iPSC-derived astrocytes.PMID:37730545 | PMC:PMC10512486 | DOI:10.1186/s12575-023-00218-x (Source: Biological Procedures Online)
Source: Biological Procedures Online - September 20, 2023 Category: Molecular Biology Authors: Patrycja Mulica Carmen Venegas Zied Landoulsi Katja Badanjak Sylvie Delcambre Maria Tziortziou Soraya Hezzaz Jenny Ghelfi Semra Smajic Jens Schwamborn Rejko Kr üger Paul Antony Patrick May Enrico Glaab Anne Gr ünewald Sandro L Pereira Source Type: research
Comparison of two protocols for the generation of iPSC-derived human astrocytes
CONCLUSIONS: Overall, our analyses highlight the need to consider the advantages and disadvantages of a given differentiation protocol, when designing functional or drug discovery studies involving iPSC-derived astrocytes.PMID:37730545 | PMC:PMC10512486 | DOI:10.1186/s12575-023-00218-x (Source: Biological Procedures Online)
Source: Biological Procedures Online - September 20, 2023 Category: Molecular Biology Authors: Patrycja Mulica Carmen Venegas Zied Landoulsi Katja Badanjak Sylvie Delcambre Maria Tziortziou Soraya Hezzaz Jenny Ghelfi Semra Smajic Jens Schwamborn Rejko Kr üger Paul Antony Patrick May Enrico Glaab Anne Gr ünewald Sandro L Pereira Source Type: research
Comparison of two protocols for the generation of iPSC-derived human astrocytes
CONCLUSIONS: Overall, our analyses highlight the need to consider the advantages and disadvantages of a given differentiation protocol, when designing functional or drug discovery studies involving iPSC-derived astrocytes.PMID:37730545 | PMC:PMC10512486 | DOI:10.1186/s12575-023-00218-x (Source: Biological Procedures Online)
Source: Biological Procedures Online - September 20, 2023 Category: Molecular Biology Authors: Patrycja Mulica Carmen Venegas Zied Landoulsi Katja Badanjak Sylvie Delcambre Maria Tziortziou Soraya Hezzaz Jenny Ghelfi Semra Smajic Jens Schwamborn Rejko Kr üger Paul Antony Patrick May Enrico Glaab Anne Gr ünewald Sandro L Pereira Source Type: research
Comparison of two protocols for the generation of iPSC-derived human astrocytes
CONCLUSIONS: Overall, our analyses highlight the need to consider the advantages and disadvantages of a given differentiation protocol, when designing functional or drug discovery studies involving iPSC-derived astrocytes.PMID:37730545 | PMC:PMC10512486 | DOI:10.1186/s12575-023-00218-x (Source: Biological Procedures Online)
Source: Biological Procedures Online - September 20, 2023 Category: Molecular Biology Authors: Patrycja Mulica Carmen Venegas Zied Landoulsi Katja Badanjak Sylvie Delcambre Maria Tziortziou Soraya Hezzaz Jenny Ghelfi Semra Smajic Jens Schwamborn Rejko Kr üger Paul Antony Patrick May Enrico Glaab Anne Gr ünewald Sandro L Pereira Source Type: research
Comparison of two protocols for the generation of iPSC-derived human astrocytes
CONCLUSIONS: Overall, our analyses highlight the need to consider the advantages and disadvantages of a given differentiation protocol, when designing functional or drug discovery studies involving iPSC-derived astrocytes.PMID:37730545 | PMC:PMC10512486 | DOI:10.1186/s12575-023-00218-x (Source: Biological Procedures Online)
Source: Biological Procedures Online - September 20, 2023 Category: Molecular Biology Authors: Patrycja Mulica Carmen Venegas Zied Landoulsi Katja Badanjak Sylvie Delcambre Maria Tziortziou Soraya Hezzaz Jenny Ghelfi Semra Smajic Jens Schwamborn Rejko Kr üger Paul Antony Patrick May Enrico Glaab Anne Gr ünewald Sandro L Pereira Source Type: research
Comparison of two protocols for the generation of iPSC-derived human astrocytes
CONCLUSIONS: Overall, our analyses highlight the need to consider the advantages and disadvantages of a given differentiation protocol, when designing functional or drug discovery studies involving iPSC-derived astrocytes.PMID:37730545 | PMC:PMC10512486 | DOI:10.1186/s12575-023-00218-x (Source: Biological Procedures Online)
Source: Biological Procedures Online - September 20, 2023 Category: Molecular Biology Authors: Patrycja Mulica Carmen Venegas Zied Landoulsi Katja Badanjak Sylvie Delcambre Maria Tziortziou Soraya Hezzaz Jenny Ghelfi Semra Smajic Jens Schwamborn Rejko Kr üger Paul Antony Patrick May Enrico Glaab Anne Gr ünewald Sandro L Pereira Source Type: research
