The role of three-dimensional scaffolds based on polyglycerol sebacate/ polycaprolactone/ gelatin in the presence of Nanohydroxyapatite in promoting chondrogenic differentiation of human adipose-derived mesenchymal stem cells
CONCLUSIONS: Our findings demonstrated that these nanocomposite scaffolds promote the differentiation of hADSCs into chondrocytes possibly by the increase in mRNA levels of collagen II, aggrecan, and Sox9 as markers of chondrogenic differentiation. In conclusion, the addition of PCL, Gelatin, and HA into PGS is a practical approach to adjust the general features of PGS to prepare a promising scaffold for cartilage tissue engineering.PMID:36964481 | PMC:PMC10039520 | DOI:10.1186/s12575-023-00197-z (Source: Biological Procedures Online)
Source: Biological Procedures Online - March 25, 2023 Category: Molecular Biology Authors: Pardis Yousefi Talouki Saeed Hesami Tackallou Shahrokh Shojaei Soheila Zamanlui Benisi Vahabodin Goodarzi Source Type: research

The role of three-dimensional scaffolds based on polyglycerol sebacate/ polycaprolactone/ gelatin in the presence of Nanohydroxyapatite in promoting chondrogenic differentiation of human adipose-derived mesenchymal stem cells
CONCLUSIONS: Our findings demonstrated that these nanocomposite scaffolds promote the differentiation of hADSCs into chondrocytes possibly by the increase in mRNA levels of collagen II, aggrecan, and Sox9 as markers of chondrogenic differentiation. In conclusion, the addition of PCL, Gelatin, and HA into PGS is a practical approach to adjust the general features of PGS to prepare a promising scaffold for cartilage tissue engineering.PMID:36964481 | PMC:PMC10039520 | DOI:10.1186/s12575-023-00197-z (Source: Biological Procedures Online)
Source: Biological Procedures Online - March 25, 2023 Category: Molecular Biology Authors: Pardis Yousefi Talouki Saeed Hesami Tackallou Shahrokh Shojaei Soheila Zamanlui Benisi Vahabodin Goodarzi Source Type: research

The role of three-dimensional scaffolds based on polyglycerol sebacate/ polycaprolactone/ gelatin in the presence of Nanohydroxyapatite in promoting chondrogenic differentiation of human adipose-derived mesenchymal stem cells
CONCLUSIONS: Our findings demonstrated that these nanocomposite scaffolds promote the differentiation of hADSCs into chondrocytes possibly by the increase in mRNA levels of collagen II, aggrecan, and Sox9 as markers of chondrogenic differentiation. In conclusion, the addition of PCL, Gelatin, and HA into PGS is a practical approach to adjust the general features of PGS to prepare a promising scaffold for cartilage tissue engineering.PMID:36964481 | PMC:PMC10039520 | DOI:10.1186/s12575-023-00197-z (Source: Biological Procedures Online)
Source: Biological Procedures Online - March 25, 2023 Category: Molecular Biology Authors: Pardis Yousefi Talouki Saeed Hesami Tackallou Shahrokh Shojaei Soheila Zamanlui Benisi Vahabodin Goodarzi Source Type: research

The role of three-dimensional scaffolds based on polyglycerol sebacate/ polycaprolactone/ gelatin in the presence of Nanohydroxyapatite in promoting chondrogenic differentiation of human adipose-derived mesenchymal stem cells
CONCLUSIONS: Our findings demonstrated that these nanocomposite scaffolds promote the differentiation of hADSCs into chondrocytes possibly by the increase in mRNA levels of collagen II, aggrecan, and Sox9 as markers of chondrogenic differentiation. In conclusion, the addition of PCL, Gelatin, and HA into PGS is a practical approach to adjust the general features of PGS to prepare a promising scaffold for cartilage tissue engineering.PMID:36964481 | PMC:PMC10039520 | DOI:10.1186/s12575-023-00197-z (Source: Biological Procedures Online)
Source: Biological Procedures Online - March 25, 2023 Category: Molecular Biology Authors: Pardis Yousefi Talouki Saeed Hesami Tackallou Shahrokh Shojaei Soheila Zamanlui Benisi Vahabodin Goodarzi Source Type: research

The role of three-dimensional scaffolds based on polyglycerol sebacate/ polycaprolactone/ gelatin in the presence of Nanohydroxyapatite in promoting chondrogenic differentiation of human adipose-derived mesenchymal stem cells
CONCLUSIONS: Our findings demonstrated that these nanocomposite scaffolds promote the differentiation of hADSCs into chondrocytes possibly by the increase in mRNA levels of collagen II, aggrecan, and Sox9 as markers of chondrogenic differentiation. In conclusion, the addition of PCL, Gelatin, and HA into PGS is a practical approach to adjust the general features of PGS to prepare a promising scaffold for cartilage tissue engineering.PMID:36964481 | PMC:PMC10039520 | DOI:10.1186/s12575-023-00197-z (Source: Biological Procedures Online)
Source: Biological Procedures Online - March 25, 2023 Category: Molecular Biology Authors: Pardis Yousefi Talouki Saeed Hesami Tackallou Shahrokh Shojaei Soheila Zamanlui Benisi Vahabodin Goodarzi Source Type: research