Deep learning classification of uveal melanoma based on histopathological images and identification of a novel indicator for prognosis of patients
CONCLUSIONS: Our findings suggest that DL model can accurately predict vital status in UM patents just using histopathological images. We found out two subgroups based on histopathological DL features, which may in favor of immunotherapy and chemotherapy. Finally, a well-performing nomogram that combines DL-signature and gene-signature was constructed to give a more straightforward and reliable prognosis for UM patients in treatment and management.PMID:37268878 | PMC:PMC10239131 | DOI:10.1186/s12575-023-00207-0 (Source: Biological Procedures Online)
Source: Biological Procedures Online - June 2, 2023 Category: Molecular Biology Authors: Qi Wan Xiang Ren Ran Wei Shali Yue Lixiang Wang Hongbo Yin Jing Tang Ming Zhang Ke Ma Ying-Ping Deng Source Type: research
A multi-omics analysis reveals CLSPN is associated with prognosis, immune microenvironment and drug resistance in cancers
CONCLUSION: Our multi-omics analysis offers a systematic understanding of the roles of CLSPN in pan-cancer and provides a potential target for future cancer treatment.PMID:37268895 | PMC:PMC10239117 | DOI:10.1186/s12575-023-00201-6 (Source: Biological Procedures Online)
Source: Biological Procedures Online - June 2, 2023 Category: Molecular Biology Authors: Yihong Chen Haicheng Wen Yin Li Ying Han Jun Tan Cao Guo Changjing Cai Ping Liu Yinghui Peng Yihan Liu Xinwen Wang Shan Zeng Ziyang Feng Hong Shen Source Type: research
Deep learning classification of uveal melanoma based on histopathological images and identification of a novel indicator for prognosis of patients
CONCLUSIONS: Our findings suggest that DL model can accurately predict vital status in UM patents just using histopathological images. We found out two subgroups based on histopathological DL features, which may in favor of immunotherapy and chemotherapy. Finally, a well-performing nomogram that combines DL-signature and gene-signature was constructed to give a more straightforward and reliable prognosis for UM patients in treatment and management.PMID:37268878 | PMC:PMC10239131 | DOI:10.1186/s12575-023-00207-0 (Source: Biological Procedures Online)
Source: Biological Procedures Online - June 2, 2023 Category: Molecular Biology Authors: Qi Wan Xiang Ren Ran Wei Shali Yue Lixiang Wang Hongbo Yin Jing Tang Ming Zhang Ke Ma Ying-Ping Deng Source Type: research
A multi-omics analysis reveals CLSPN is associated with prognosis, immune microenvironment and drug resistance in cancers
CONCLUSION: Our multi-omics analysis offers a systematic understanding of the roles of CLSPN in pan-cancer and provides a potential target for future cancer treatment.PMID:37268895 | PMC:PMC10239117 | DOI:10.1186/s12575-023-00201-6 (Source: Biological Procedures Online)
Source: Biological Procedures Online - June 2, 2023 Category: Molecular Biology Authors: Yihong Chen Haicheng Wen Yin Li Ying Han Jun Tan Cao Guo Changjing Cai Ping Liu Yinghui Peng Yihan Liu Xinwen Wang Shan Zeng Ziyang Feng Hong Shen Source Type: research
Deep learning classification of uveal melanoma based on histopathological images and identification of a novel indicator for prognosis of patients
CONCLUSIONS: Our findings suggest that DL model can accurately predict vital status in UM patents just using histopathological images. We found out two subgroups based on histopathological DL features, which may in favor of immunotherapy and chemotherapy. Finally, a well-performing nomogram that combines DL-signature and gene-signature was constructed to give a more straightforward and reliable prognosis for UM patients in treatment and management.PMID:37268878 | PMC:PMC10239131 | DOI:10.1186/s12575-023-00207-0 (Source: Biological Procedures Online)
Source: Biological Procedures Online - June 2, 2023 Category: Molecular Biology Authors: Qi Wan Xiang Ren Ran Wei Shali Yue Lixiang Wang Hongbo Yin Jing Tang Ming Zhang Ke Ma Ying-Ping Deng Source Type: research
A multi-omics analysis reveals CLSPN is associated with prognosis, immune microenvironment and drug resistance in cancers
CONCLUSION: Our multi-omics analysis offers a systematic understanding of the roles of CLSPN in pan-cancer and provides a potential target for future cancer treatment.PMID:37268895 | PMC:PMC10239117 | DOI:10.1186/s12575-023-00201-6 (Source: Biological Procedures Online)
Source: Biological Procedures Online - June 2, 2023 Category: Molecular Biology Authors: Yihong Chen Haicheng Wen Yin Li Ying Han Jun Tan Cao Guo Changjing Cai Ping Liu Yinghui Peng Yihan Liu Xinwen Wang Shan Zeng Ziyang Feng Hong Shen Source Type: research
Deep learning classification of uveal melanoma based on histopathological images and identification of a novel indicator for prognosis of patients
CONCLUSIONS: Our findings suggest that DL model can accurately predict vital status in UM patents just using histopathological images. We found out two subgroups based on histopathological DL features, which may in favor of immunotherapy and chemotherapy. Finally, a well-performing nomogram that combines DL-signature and gene-signature was constructed to give a more straightforward and reliable prognosis for UM patients in treatment and management.PMID:37268878 | PMC:PMC10239131 | DOI:10.1186/s12575-023-00207-0 (Source: Biological Procedures Online)
Source: Biological Procedures Online - June 2, 2023 Category: Molecular Biology Authors: Qi Wan Xiang Ren Ran Wei Shali Yue Lixiang Wang Hongbo Yin Jing Tang Ming Zhang Ke Ma Ying-Ping Deng Source Type: research
A multi-omics analysis reveals CLSPN is associated with prognosis, immune microenvironment and drug resistance in cancers
CONCLUSION: Our multi-omics analysis offers a systematic understanding of the roles of CLSPN in pan-cancer and provides a potential target for future cancer treatment.PMID:37268895 | PMC:PMC10239117 | DOI:10.1186/s12575-023-00201-6 (Source: Biological Procedures Online)
Source: Biological Procedures Online - June 2, 2023 Category: Molecular Biology Authors: Yihong Chen Haicheng Wen Yin Li Ying Han Jun Tan Cao Guo Changjing Cai Ping Liu Yinghui Peng Yihan Liu Xinwen Wang Shan Zeng Ziyang Feng Hong Shen Source Type: research
Deep learning classification of uveal melanoma based on histopathological images and identification of a novel indicator for prognosis of patients
CONCLUSIONS: Our findings suggest that DL model can accurately predict vital status in UM patents just using histopathological images. We found out two subgroups based on histopathological DL features, which may in favor of immunotherapy and chemotherapy. Finally, a well-performing nomogram that combines DL-signature and gene-signature was constructed to give a more straightforward and reliable prognosis for UM patients in treatment and management.PMID:37268878 | PMC:PMC10239131 | DOI:10.1186/s12575-023-00207-0 (Source: Biological Procedures Online)
Source: Biological Procedures Online - June 2, 2023 Category: Molecular Biology Authors: Qi Wan Xiang Ren Ran Wei Shali Yue Lixiang Wang Hongbo Yin Jing Tang Ming Zhang Ke Ma Ying-Ping Deng Source Type: research
A multi-omics analysis reveals CLSPN is associated with prognosis, immune microenvironment and drug resistance in cancers
CONCLUSION: Our multi-omics analysis offers a systematic understanding of the roles of CLSPN in pan-cancer and provides a potential target for future cancer treatment.PMID:37268895 | PMC:PMC10239117 | DOI:10.1186/s12575-023-00201-6 (Source: Biological Procedures Online)
Source: Biological Procedures Online - June 2, 2023 Category: Molecular Biology Authors: Yihong Chen Haicheng Wen Yin Li Ying Han Jun Tan Cao Guo Changjing Cai Ping Liu Yinghui Peng Yihan Liu Xinwen Wang Shan Zeng Ziyang Feng Hong Shen Source Type: research
Deep learning classification of uveal melanoma based on histopathological images and identification of a novel indicator for prognosis of patients
CONCLUSIONS: Our findings suggest that DL model can accurately predict vital status in UM patents just using histopathological images. We found out two subgroups based on histopathological DL features, which may in favor of immunotherapy and chemotherapy. Finally, a well-performing nomogram that combines DL-signature and gene-signature was constructed to give a more straightforward and reliable prognosis for UM patients in treatment and management.PMID:37268878 | PMC:PMC10239131 | DOI:10.1186/s12575-023-00207-0 (Source: Biological Procedures Online)
Source: Biological Procedures Online - June 2, 2023 Category: Molecular Biology Authors: Qi Wan Xiang Ren Ran Wei Shali Yue Lixiang Wang Hongbo Yin Jing Tang Ming Zhang Ke Ma Ying-Ping Deng Source Type: research
A multi-omics analysis reveals CLSPN is associated with prognosis, immune microenvironment and drug resistance in cancers
CONCLUSION: Our multi-omics analysis offers a systematic understanding of the roles of CLSPN in pan-cancer and provides a potential target for future cancer treatment.PMID:37268895 | PMC:PMC10239117 | DOI:10.1186/s12575-023-00201-6 (Source: Biological Procedures Online)
Source: Biological Procedures Online - June 2, 2023 Category: Molecular Biology Authors: Yihong Chen Haicheng Wen Yin Li Ying Han Jun Tan Cao Guo Changjing Cai Ping Liu Yinghui Peng Yihan Liu Xinwen Wang Shan Zeng Ziyang Feng Hong Shen Source Type: research
Deep learning classification of uveal melanoma based on histopathological images and identification of a novel indicator for prognosis of patients
CONCLUSIONS: Our findings suggest that DL model can accurately predict vital status in UM patents just using histopathological images. We found out two subgroups based on histopathological DL features, which may in favor of immunotherapy and chemotherapy. Finally, a well-performing nomogram that combines DL-signature and gene-signature was constructed to give a more straightforward and reliable prognosis for UM patients in treatment and management.PMID:37268878 | PMC:PMC10239131 | DOI:10.1186/s12575-023-00207-0 (Source: Biological Procedures Online)
Source: Biological Procedures Online - June 2, 2023 Category: Molecular Biology Authors: Qi Wan Xiang Ren Ran Wei Shali Yue Lixiang Wang Hongbo Yin Jing Tang Ming Zhang Ke Ma Ying-Ping Deng Source Type: research
A multi-omics analysis reveals CLSPN is associated with prognosis, immune microenvironment and drug resistance in cancers
CONCLUSION: Our multi-omics analysis offers a systematic understanding of the roles of CLSPN in pan-cancer and provides a potential target for future cancer treatment.PMID:37268895 | PMC:PMC10239117 | DOI:10.1186/s12575-023-00201-6 (Source: Biological Procedures Online)
Source: Biological Procedures Online - June 2, 2023 Category: Molecular Biology Authors: Yihong Chen Haicheng Wen Yin Li Ying Han Jun Tan Cao Guo Changjing Cai Ping Liu Yinghui Peng Yihan Liu Xinwen Wang Shan Zeng Ziyang Feng Hong Shen Source Type: research
Deep learning classification of uveal melanoma based on histopathological images and identification of a novel indicator for prognosis of patients
CONCLUSIONS: Our findings suggest that DL model can accurately predict vital status in UM patents just using histopathological images. We found out two subgroups based on histopathological DL features, which may in favor of immunotherapy and chemotherapy. Finally, a well-performing nomogram that combines DL-signature and gene-signature was constructed to give a more straightforward and reliable prognosis for UM patients in treatment and management.PMID:37268878 | PMC:PMC10239131 | DOI:10.1186/s12575-023-00207-0 (Source: Biological Procedures Online)
Source: Biological Procedures Online - June 2, 2023 Category: Molecular Biology Authors: Qi Wan Xiang Ren Ran Wei Shali Yue Lixiang Wang Hongbo Yin Jing Tang Ming Zhang Ke Ma Ying-Ping Deng Source Type: research
