Targeting Mitochondrial Complex I Deficiency in MPP < sup > + < /sup > /MPTP-induced Parkinson's Disease Cell Culture and Mouse Models by Transducing Yeast NDI1 Gene
CONCLUSIONS: NDI1 compensates for the defective complex I in MPP+/MPTP-induced models, and vastly alleviates MPTP-induced toxic effect on dopaminergic neurons. Our study may provide a basis for gene therapy of sporadic PD with defective complex I caused by MPTP-like substance.PMID:38594619 | PMC:PMC11003148 | DOI:10.1186/s12575-024-00236-3 (Source: Biological Procedures Online)
Source: Biological Procedures Online - April 9, 2024 Category: Molecular Biology Authors: Hongzhi Li Jing Zhang Yuqi Shen Yifan Ye Qingyou Jiang Lan Chen Bohao Sun Zhuo Chen Luxi Shen Hezhi Fang Jifeng Yang Haihua Gu Source Type: research
Targeting Mitochondrial Complex I Deficiency in MPP < sup > + < /sup > /MPTP-induced Parkinson's Disease Cell Culture and Mouse Models by Transducing Yeast NDI1 Gene
CONCLUSIONS: NDI1 compensates for the defective complex I in MPP+/MPTP-induced models, and vastly alleviates MPTP-induced toxic effect on dopaminergic neurons. Our study may provide a basis for gene therapy of sporadic PD with defective complex I caused by MPTP-like substance.PMID:38594619 | PMC:PMC11003148 | DOI:10.1186/s12575-024-00236-3 (Source: Biological Procedures Online)
Source: Biological Procedures Online - April 9, 2024 Category: Molecular Biology Authors: Hongzhi Li Jing Zhang Yuqi Shen Yifan Ye Qingyou Jiang Lan Chen Bohao Sun Zhuo Chen Luxi Shen Hezhi Fang Jifeng Yang Haihua Gu Source Type: research
Targeting Mitochondrial Complex I Deficiency in MPP < sup > + < /sup > /MPTP-induced Parkinson's Disease Cell Culture and Mouse Models by Transducing Yeast NDI1 Gene
CONCLUSIONS: NDI1 compensates for the defective complex I in MPP+/MPTP-induced models, and vastly alleviates MPTP-induced toxic effect on dopaminergic neurons. Our study may provide a basis for gene therapy of sporadic PD with defective complex I caused by MPTP-like substance.PMID:38594619 | PMC:PMC11003148 | DOI:10.1186/s12575-024-00236-3 (Source: Biological Procedures Online)
Source: Biological Procedures Online - April 9, 2024 Category: Molecular Biology Authors: Hongzhi Li Jing Zhang Yuqi Shen Yifan Ye Qingyou Jiang Lan Chen Bohao Sun Zhuo Chen Luxi Shen Hezhi Fang Jifeng Yang Haihua Gu Source Type: research
Targeting Mitochondrial Complex I Deficiency in MPP < sup > + < /sup > /MPTP-induced Parkinson's Disease Cell Culture and Mouse Models by Transducing Yeast NDI1 Gene
CONCLUSIONS: NDI1 compensates for the defective complex I in MPP+/MPTP-induced models, and vastly alleviates MPTP-induced toxic effect on dopaminergic neurons. Our study may provide a basis for gene therapy of sporadic PD with defective complex I caused by MPTP-like substance.PMID:38594619 | PMC:PMC11003148 | DOI:10.1186/s12575-024-00236-3 (Source: Biological Procedures Online)
Source: Biological Procedures Online - April 9, 2024 Category: Molecular Biology Authors: Hongzhi Li Jing Zhang Yuqi Shen Yifan Ye Qingyou Jiang Lan Chen Bohao Sun Zhuo Chen Luxi Shen Hezhi Fang Jifeng Yang Haihua Gu Source Type: research
Targeting Mitochondrial Complex I Deficiency in MPP < sup > + < /sup > /MPTP-induced Parkinson's Disease Cell Culture and Mouse Models by Transducing Yeast NDI1 Gene
CONCLUSIONS: NDI1 compensates for the defective complex I in MPP+/MPTP-induced models, and vastly alleviates MPTP-induced toxic effect on dopaminergic neurons. Our study may provide a basis for gene therapy of sporadic PD with defective complex I caused by MPTP-like substance.PMID:38594619 | DOI:10.1186/s12575-024-00236-3 (Source: Biological Procedures Online)
Source: Biological Procedures Online - April 9, 2024 Category: Molecular Biology Authors: Hongzhi Li Jing Zhang Yuqi Shen Yifan Ye Qingyou Jiang Lan Chen Bohao Sun Zhuo Chen Luxi Shen Hezhi Fang Jifeng Yang Haihua Gu Source Type: research
Correction: Analysis and Interpretation of Metagenomics Data: An Approach
Biol Proced Online. 2024 Apr 4;26(1):8. doi: 10.1186/s12575-024-00235-4.NO ABSTRACTPMID:38575906 | PMC:PMC10993473 | DOI:10.1186/s12575-024-00235-4 (Source: Biological Procedures Online)
Source: Biological Procedures Online - April 4, 2024 Category: Molecular Biology Authors: Gauri S Navgire Neha Goel Gifty Sawhney Mohit Sharma Prashant Kaushik Yugal Kishore Mohanta Tapan Kumar Mohanta Ahmed Al-Harrasi Source Type: research
Correction: Analysis and Interpretation of Metagenomics Data: An Approach
Biol Proced Online. 2024 Apr 4;26(1):8. doi: 10.1186/s12575-024-00235-4.NO ABSTRACTPMID:38575906 | PMC:PMC10993473 | DOI:10.1186/s12575-024-00235-4 (Source: Biological Procedures Online)
Source: Biological Procedures Online - April 4, 2024 Category: Molecular Biology Authors: Gauri S Navgire Neha Goel Gifty Sawhney Mohit Sharma Prashant Kaushik Yugal Kishore Mohanta Tapan Kumar Mohanta Ahmed Al-Harrasi Source Type: research
Correction: Analysis and Interpretation of Metagenomics Data: An Approach
Biol Proced Online. 2024 Apr 4;26(1):8. doi: 10.1186/s12575-024-00235-4.NO ABSTRACTPMID:38575906 | PMC:PMC10993473 | DOI:10.1186/s12575-024-00235-4 (Source: Biological Procedures Online)
Source: Biological Procedures Online - April 4, 2024 Category: Molecular Biology Authors: Gauri S Navgire Neha Goel Gifty Sawhney Mohit Sharma Prashant Kaushik Yugal Kishore Mohanta Tapan Kumar Mohanta Ahmed Al-Harrasi Source Type: research
Correction: Analysis and Interpretation of Metagenomics Data: An Approach
Biol Proced Online. 2024 Apr 4;26(1):8. doi: 10.1186/s12575-024-00235-4.NO ABSTRACTPMID:38575906 | DOI:10.1186/s12575-024-00235-4 (Source: Biological Procedures Online)
Source: Biological Procedures Online - April 4, 2024 Category: Molecular Biology Authors: Gauri S Navgire Neha Goel Gifty Sawhney Mohit Sharma Prashant Kaushik Yugal Kishore Mohanta Tapan Kumar Mohanta Ahmed Al-Harrasi Source Type: research
A novel method to efficiently differentiate human osteoclasts from blood-derived monocytes
CONCLUSION: Our study has established a novel protocol for the isolation of primary human osteoclasts that improves osteoclastogenesis in comparison to the conventionally used cultivation approach.PMID:38504200 | PMC:PMC10949786 | DOI:10.1186/s12575-024-00233-6 (Source: Biological Procedures Online)
Source: Biological Procedures Online - March 20, 2024 Category: Molecular Biology Authors: Suganja Chandrabalan Linh Dang Uwe Hansen Melanie Timmen Corinna Wehmeyer Richard Stange Tim Bei ßbarth Claudia Binder Annalen Bleckmann Kerstin Menck Source Type: research
A novel method to efficiently differentiate human osteoclasts from blood-derived monocytes
CONCLUSION: Our study has established a novel protocol for the isolation of primary human osteoclasts that improves osteoclastogenesis in comparison to the conventionally used cultivation approach.PMID:38504200 | PMC:PMC10949786 | DOI:10.1186/s12575-024-00233-6 (Source: Biological Procedures Online)
Source: Biological Procedures Online - March 20, 2024 Category: Molecular Biology Authors: Suganja Chandrabalan Linh Dang Uwe Hansen Melanie Timmen Corinna Wehmeyer Richard Stange Tim Bei ßbarth Claudia Binder Annalen Bleckmann Kerstin Menck Source Type: research
A novel method to efficiently differentiate human osteoclasts from blood-derived monocytes
CONCLUSION: Our study has established a novel protocol for the isolation of primary human osteoclasts that improves osteoclastogenesis in comparison to the conventionally used cultivation approach.PMID:38504200 | PMC:PMC10949786 | DOI:10.1186/s12575-024-00233-6 (Source: Biological Procedures Online)
Source: Biological Procedures Online - March 20, 2024 Category: Molecular Biology Authors: Suganja Chandrabalan Linh Dang Uwe Hansen Melanie Timmen Corinna Wehmeyer Richard Stange Tim Bei ßbarth Claudia Binder Annalen Bleckmann Kerstin Menck Source Type: research
A novel method to efficiently differentiate human osteoclasts from blood-derived monocytes
CONCLUSION: Our study has established a novel protocol for the isolation of primary human osteoclasts that improves osteoclastogenesis in comparison to the conventionally used cultivation approach.PMID:38504200 | PMC:PMC10949786 | DOI:10.1186/s12575-024-00233-6 (Source: Biological Procedures Online)
Source: Biological Procedures Online - March 20, 2024 Category: Molecular Biology Authors: Suganja Chandrabalan Linh Dang Uwe Hansen Melanie Timmen Corinna Wehmeyer Richard Stange Tim Bei ßbarth Claudia Binder Annalen Bleckmann Kerstin Menck Source Type: research
A novel method to efficiently differentiate human osteoclasts from blood-derived monocytes
CONCLUSION: Our study has established a novel protocol for the isolation of primary human osteoclasts that improves osteoclastogenesis in comparison to the conventionally used cultivation approach.PMID:38504200 | PMC:PMC10949786 | DOI:10.1186/s12575-024-00233-6 (Source: Biological Procedures Online)
Source: Biological Procedures Online - March 20, 2024 Category: Molecular Biology Authors: Suganja Chandrabalan Linh Dang Uwe Hansen Melanie Timmen Corinna Wehmeyer Richard Stange Tim Bei ßbarth Claudia Binder Annalen Bleckmann Kerstin Menck Source Type: research
A novel method to efficiently differentiate human osteoclasts from blood-derived monocytes
CONCLUSION: Our study has established a novel protocol for the isolation of primary human osteoclasts that improves osteoclastogenesis in comparison to the conventionally used cultivation approach.PMID:38504200 | PMC:PMC10949786 | DOI:10.1186/s12575-024-00233-6 (Source: Biological Procedures Online)
Source: Biological Procedures Online - March 20, 2024 Category: Molecular Biology Authors: Suganja Chandrabalan Linh Dang Uwe Hansen Melanie Timmen Corinna Wehmeyer Richard Stange Tim Bei ßbarth Claudia Binder Annalen Bleckmann Kerstin Menck Source Type: research
