The New Era of Retinal Imaging in Hypertensive Patients
Structural and functional alterations in the microcirculation by systemic hypertension can cause significant organ damage at the eye, heart, brain, and kidneys. As the retina is the only tissue in the body that allows direct imaging of small vessels, the relationship of hypertensive retinopathy signs with development of disease states in other organs have been extensively studied; large-scale epidemiological studies using fundus photography and advanced semi-automated analysis software have reported the association of retinopathy signs with hypertensive end-organ damage includes the following: stroke, dementia, and coronar...
Source: Asia-Pacific Journal of Ophthalmology - March 1, 2022 Category: Opthalmology Tags: Review Article Source Type: research

Retinal Biomarkers for Alzheimer Disease: The Facts and the Future
Alzheimer disease (AD) is a significant cause of morbidity and mortality worldwide, with limited treatment options and considerable diagnostic challenges. Identification and validation of retinal changes that correlate with clinicopathologic features of AD could provide a noninvasive method of screening and monitoring progression of disease, with notable implications for developing new therapies, particularly in its preclinical stages. Retinal biomarkers that have been studied to date include structural changes in neurosensory retinal layers, alterations in vascular architecture and function, and pathologic deposition of p...
Source: Asia-Pacific Journal of Ophthalmology - March 1, 2022 Category: Opthalmology Tags: Review Article Source Type: research

Detection of Systemic Diseases From Ocular Images Using Artificial Intelligence: A Systematic Review
Conclusions: Ocular image – based artificial intelligence possesses potential diagnostic power to screen various systemic diseases and has also demonstrated the ability to detect Alzheimer and chronic kidney diseases at early stages. Further research is needed to validate these models for real-world implementation. (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - March 1, 2022 Category: Opthalmology Tags: Review Article Source Type: research

Artificial Intelligence Meets Neuro-Ophthalmology
Recent advances in artificial intelligence have provided ophthalmologists with fast, accurate, and automated means for diagnosing and treating ocular conditions, paving the way to a modern and scalable eye care system. Compared to other ophthalmic disciplines, neuro-ophthalmology has, until recently, not benefitted from significant advances in the area of artificial intelligence. In this narrative review, we summarize and discuss recent advancements utilizing artificial intelligence for the detection of structural and functional optic nerve head abnormalities, and ocular movement disorders in neuro-ophthalmology. (Source: ...
Source: Asia-Pacific Journal of Ophthalmology - March 1, 2022 Category: Opthalmology Tags: Review Article Source Type: research

Age-Related Macular Degeneration Masquerade: A Review of Pentosan Polysulfate Maculopathy and Implications for Clinical Practice
Pentosan polysulfate (PPS) sodium (Elmiron) is the only Food and Drug Administration (FDA)–approved oral medication to treat interstitial cystitis, also known as bladder pain syndrome. A symptomatic pigmentary maculopathy associated with PPS was reported in 2018. Since then, recognition of this unique drug toxicity has increased rapidly. This potentially sight-threatening side effect prompted the FDA in June 2020 to update the label for PPS to warn about “retinal pigmentary changes.” A challenging feature of pentosan maculopathy is its ability to mimic many other retinal conditions, including inherited retinal dystro...
Source: Asia-Pacific Journal of Ophthalmology - March 1, 2022 Category: Opthalmology Tags: Review Article Source Type: research

Age-Related Macular Degeneration and Cardiovascular Diseases: Revisiting the Common Soil Theory
Age-related macular degeneration (AMD), a complex disease associated with aging, remains one of the leading causes of visual loss in high-income countries and its prevalence is expected to increase over the next decades. Polypoidal choroidal vasculopathy has been considered a variant of neovascular AMD and is highly prevalent in Asian populations. Similarly, cardiovascular disease (CVD)—another complex disease associated with aging—is a leading cause of morbidity and mortality in high-income countries and its prevalence is also expected to increase due to population aging. Previous studies reported an increased risk fo...
Source: Asia-Pacific Journal of Ophthalmology - March 1, 2022 Category: Opthalmology Tags: Review Article Source Type: research

The Eye Is a Window to Systemic and Neuro-Ophthalmic Diseases
No abstract available (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - March 1, 2022 Category: Opthalmology Tags: Editorial Source Type: research

Concerning the Paper “Ocular Surface Microbiome in Health and Disease”
No abstract available (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - January 1, 2022 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Comment on Microbial Keratitis After Collagen Cross-linking for Corneal Ectasia
No abstract available (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - January 1, 2022 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Symmetrical Nasal Ectopia Lentis
No abstract available (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - January 1, 2022 Category: Opthalmology Tags: Intriguing Images Source Type: research

Nd:YAG Laser Photodisruptive Shockwave Causing Damages to Intraocular Lens
No abstract available (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - January 1, 2022 Category: Opthalmology Tags: Intriguing Images Source Type: research

Peripapillary Retinoschisis Mimicking Normal Retinal Nerve Fiber Layer
No abstract available (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - January 1, 2022 Category: Opthalmology Tags: Intriguing Images Source Type: research

Crater Within Crater: Double Coloboma
No abstract available (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - January 1, 2022 Category: Opthalmology Tags: Intriguing Images Source Type: research

Vision Impairment and Productivity Among Female Garment Workers in Bangladesh: A Cohort Study
Purpose: To assess the prevalence of near and correctable distance visual impairment among screened participants in the garment industry and to explore associations with income, age, and urban versus rural residence. Methods: Vision screenings were conducted at 4 garment factories, 2 urban and 2 rural locations during September and October 2019. Distance vision impairment was the presence of uncorrected vision of (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - January 1, 2022 Category: Opthalmology Tags: Original Study Source Type: research

Visual Impairment and Risk of Self-Reported Road Traffic Crashes Among Bus Drivers in Bangladesh
This study assesses the prevalence and the causes of visual impairment among bus drivers undergoing screening in Bangladesh and associations with self-reported crashes. Methods: Eye health screenings including refraction and questionnaires were conducted at 10 bus terminals in 7 districts of Bangladesh from June through August 2019. Presenting near and distance visual impairment and self-reported road traffic crashes were recorded. Results: Among 700 participants, nearly 1 in 5 (n = 126, 18.0%) had presented visual acuity (VA) in the better-seeing eye ≤6/9, not meeting the vision standard of Bangladesh ...
Source: Asia-Pacific Journal of Ophthalmology - January 1, 2022 Category: Opthalmology Tags: Original Study Source Type: research