Ocular, Orbital, and Sinus Damage Induced by a Fierce Fishhook Trauma
No abstract available (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - March 1, 2021 Category: Opthalmology Tags: Intriguing Images Source Type: research

“Hematocrit Sign” in PEVAC Lesion
No abstract available (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - March 1, 2021 Category: Opthalmology Tags: Intriguing Images Source Type: research

Current Approach for the Diagnosis and Management of Noninfective Scleritis
Scleritis is a rare, vision-threatening inflammation of the sclera that is often associated with life-threatening systemic illnesses. Rheumatoid arthritis remains the most common associated systemic rheumatic disease and the commonest systemic association of scleritis. Granulomatosis with polyangiitis is the most common cause of vasculitis-associated scleritis. The etiopathogenesis of scleritis remains unclear, but can be immune complex-mediated or due to a local delayed hypersensitivity reaction. Scleritis can involve either the anterior or posterior sclera, and has a wide spectrum of clinical presentations. Among the sub...
Source: Asia-Pacific Journal of Ophthalmology - March 1, 2021 Category: Opthalmology Tags: Review Article Source Type: research

Electroretinogram and Visual Field Correlation in Birdshot Chorioretinopathy
Purpose: The aim of this study was to assess possible correlation between the visual field and electroretinogram (ERG) parameters in birdshot chorioretinopathy (BCR). Design: Retrospective cross-sectional study. Methods: This single-center study included 21 eyes of 11 patients with BCR with prior ERG and Goldmann kinetic perimetry. Generalized estimating equation was used for statistical analysis, and isopters V4e and I4e were modeled as separate outcomes with each parameter of ERG as the main independent variable. The main outcome measure was presence or absence of correlation between the Goldmann isopte...
Source: Asia-Pacific Journal of Ophthalmology - March 1, 2021 Category: Opthalmology Tags: Original Study Source Type: research

Optical Coherence Tomography Angiography Assessment of Macular Choriocapillaris and Choroid Following Panretinal Photocoagulation in a Diverse Population With Advanced Diabetic Retinopathy
Conclusions: OCTA demonstrates redistribution of choroidal circulation from the periphery to the macula after PRP, with increased macular CT and stable choroidal blood flow density. Eyes with greater macular thickness are more likely to experience an increase in CRT. (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - March 1, 2021 Category: Opthalmology Tags: Original Study - Clinical Source Type: research

Chemotherapy for Retinoblastoma: Impact of Intravitreal Chemotherapy
Chemotherapy is now the primary treatment of retinoblastoma in eyes with visual potential or those that are considered not advanced for retinoblastoma. In addition to intravenous chemotherapy (IVC), drugs delivered via alternative routes such as intra-arterial and intravitreal administration have emerged as promising options for management of retinoblastoma. Various studies have shown excellent results in salvaging nearly 100% of groups A–C eyes; however, intra-arterial chemotherapy (IAC) seems to offer superior local control rates as compared with IVC for advanced intraocular retinoblastoma (groups D and E eyes). Intrav...
Source: Asia-Pacific Journal of Ophthalmology - March 1, 2021 Category: Opthalmology Tags: Perspectives Source Type: research

Screening for Retinoblastoma: A Systematic Review of Current Strategies
Conclusions: Several screening programs for early detection of retinoblastoma are evolving in the developing countries, but the practices are not uniform. Universal newborn screening should be the norm. Newer tools and software can be utilized to screen infants on a community scale. Focussed research on revolutionizing digital imaging for a versatile screening tool holds promise for early diagnosis of retinoblastoma. (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - March 1, 2021 Category: Opthalmology Tags: Review Article Source Type: research

Smaller Anterior Chamber Volume Is Associated With Higher Risk of Intraocular Pressure Elevation After Laser Peripheral Iridotomy: A 1-Year Follow-Up Study
Conclusions: ACV is a reliable and accurate predictor for the outcome of PACD. Due to its 3-dimensional nature, the robustness of ACV is greater than traditional angle width parameters such as TISA750. (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - March 1, 2021 Category: Opthalmology Tags: Original Study Source Type: research

Two-Year Clinical Outcomes of Combined Phacoemulsification, Goniosynechialysis, and Excisional Goniotomy For Angle-Closure Glaucoma
Purpose: The aim of this study was to describe changes in intraocular pressure (IOP) and IOP medications after phacoemulsification with Kahook Dual Blade-assisted goniosynechialysis and excisional goniotomy in eyes with angle-closure glaucoma and cataract. Design: Retrospective case series. Methods: Data were collected retrospectively through 24 months of follow-up in 42 eyes of 24 subjects. Results: Preoperative mean (SE) IOP was 25.5 (0.7) mm Hg using a mean of 2.3 (0.1) medications per eye. At month 24, mean IOP had decreased to 13.5 (0.4) mm Hg [a reduction of 12.0 mm Hg (47.1%); P  (Source: ...
Source: Asia-Pacific Journal of Ophthalmology - March 1, 2021 Category: Opthalmology Tags: Original Clinical Study Source Type: research

Systemic Genotype-Phenotype Analysis of MYOC Variants Based on Exome Sequencing and Literature Review
Conclusions: Most MYOC variants contributing to adPOAG could be characterized as rare missense variants located in OLF-domain and predicted to be damaging through multiple tools. The effect of other variants, especially for truncation variants (except for p.Q368∗) need further clarification. (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - March 1, 2021 Category: Opthalmology Tags: Original Study Source Type: research

Peripapillary Perfused Capillary Density in Acute Angle-Closure Glaucoma: An Optical Coherence Tomography Angiography Study
Conclusions: The degree of microvascular attenuation in AAC eyes was not different from that in POAG eyes. (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - March 1, 2021 Category: Opthalmology Tags: Original Study Source Type: research

Advanced Research in Scleral Cross-Linking to Prevent From Progressive Myopia
Riboflavin-ultraviolet A (UVA) collagen cross-linking (CXL) has been applied in clinical settings to prevent the progression of keratoconus and corneal dilatation caused by other reasons in past decades. As CXL with riboflavin-UVA can enhance the stiffness of collagen-rich tissues, this technique has been further used on sclera to investigate as a safe and effective myopia prevention treatment. Despite the riboflavin-UVA scleral CXL is still in the animal and in vitro experimental phases and the mechanism is not very clear, it is promising to control myopia development clinically. In this article, researches on the laborat...
Source: Asia-Pacific Journal of Ophthalmology - March 1, 2021 Category: Opthalmology Tags: Review Article Source Type: research

Intracorneal Ring Segments Followed by Simultaneous Topography-Guided Removal of Epithelium and Stroma With Accelerated Collagen Cross-Linking For Keratoconus (I-TRESK/CXL)
Purpose: The aim of this study was to assess the visual, topographic, and aberrometric outcomes of a novel tissue sparing technique, topography-guided removal of epithelium, and stroma in keratoconus (TRESK) along with accelerated collagen cross-linking (CXL), 1 month after Intacs insertion. Design: Prospective interventional study. Methods: Fourty-eight eyes (45 patients) with keratoconus underwent femto-assisted Intacs insertion. After 1 month, TRESK and CXL (9 mW/cm2 for 10 minutes) was done. TRESK is a decentered trans-PTK (phototherapeutic keratectomy) with center and area of ablation at the location...
Source: Asia-Pacific Journal of Ophthalmology - March 1, 2021 Category: Opthalmology Tags: Original Study Source Type: research

Conjunctival Melanoma: Outcomes based on the American Joint Committee on Cancer Clinical Classification (8th Edition) of 425 Patients at a Single Ocular Oncology Center
Purpose: The aim of this study was to evaluate outcomes of conjunctiva melanoma based on the American Joint Committee on Cancer Classification (AJCC) 8th edition. Design: Retrospective interventional case series. Methods: Outcomes analysis of 425 patients. Results: In this analysis of 425 patients with conjunctival melanoma, there were 266 (63%) patients classified as T1, 75 (18%) as T2, 84 (20%) as T3, and 0 (0%) as T4. A comparison (T1 vs T2 vs T3) revealed that history of primary acquired melanosis was more common in T2 (81% vs 96% vs 81%; P = 0.01) and conjunctival nevus more common in T1 (...
Source: Asia-Pacific Journal of Ophthalmology - March 1, 2021 Category: Opthalmology Tags: Original Study Source Type: research

Topical Ocular Povidone-Iodine as an Adjunctive Preventative Practice in the Era of COVID-19
Ophthalmologists and patients have an inherent increased risk for transmission of SARS-CoV-2. The human ocular surface expresses receptors and enzymes facilitating transmission of SARS-CoV-2. Personal protective equipment alone provides incomplete protection. Adjunctive topical ocular, nasal, and oral antisepsis with povidone iodine bolsters personal protective equipment in prevention of provider-patient transmission of SARS-CoV-2 in ophthalmology. (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - March 1, 2021 Category: Opthalmology Tags: Perspectives Source Type: research