Utility and Feasibility of Teleophthalmology Using a Smartphone-Based Ophthalmic Camera in Screening Camps in Nepal
Conclusions: Remote ophthalmologist consultation utilizing a mobile device ophthalmic camera system is logistically feasible, easily scalable, and capable of capturing high-quality images in the setting of rural eye screening camps. Although OTs are well equipped to identify and triage anterior segment pathology, this technology may be helpful in the detection of and referral for posterior segment pathology. (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - January 1, 2020 Category: Opthalmology Tags: Original Clinical Study Source Type: research

Effects of Switching to Aflibercept in Treatment Resistant Macular Edema Secondary to Retinal Vein Occlusion
Purpose: The aim of this study was to examine 12-month outcomes of eyes switched from intravitreal ranibizumab or bevacizumab to aflibercept for cystoid macular edema due to retinal vein occlusion (RVO). Design: Retrospective, observation, case series. Methods: A retrospective study was performed assessing eyes with RVO switched to aflibercept for at least 12 months. To be included in the study, eyes had to have macular edema despite treatment for at least 6 months with bevacizumab and/or ranibizumab before the switch, central foveal thickness (CFT) ≥300 μm at time of switch, and visual acuity (VA) ≤60 e...
Source: Asia-Pacific Journal of Ophthalmology - January 1, 2020 Category: Opthalmology Tags: Original Clinical Study Source Type: research

Thyroid Eye Disease-Related Epiblepharon: A Comparative Case Study
This study describes the clinical features and management of epiblepharon as a manifestation of thyroid eye disease (TED). In addition, we compare the frequency and age in Asian and non-Asian patients, and discuss pathophysiologic implications. Design: Retrospective case-control study. Methods: This is a single-center retrospective review that identified 172 adult patients (age 19 to 83) with TED that were consecutively evaluated by 1 author (T.J.M.) between December 2015 and July 2018. Diagnosis of TED and epiblepharon was based upon clinical assessment as documented in the medical record. Results: In a cohort of...
Source: Asia-Pacific Journal of Ophthalmology - January 1, 2020 Category: Opthalmology Tags: Original Clinical Study Source Type: research

A Novel Method of CT Exophthalmometry in Patients With Thyroid Eye Disease
Purpose: Conventional computed tomography (CT) exophthalmometry requires an intact lateral orbital wall and is therefore not feasible in patients who have undergone any form of lateral orbital wall surgery where the normal bony landmark may be lost or displaced. The purpose of our study is to validate an alternative method of CT exophthalmometry utilizing the posterior clinoid (PC) process as a new reference point that will allow for reproducible comparison of the anterior-posterior globe position in the preoperative and postoperative settings. Design: Cohort study. Methods: This is a retrospective study of 48 pati...
Source: Asia-Pacific Journal of Ophthalmology - January 1, 2020 Category: Opthalmology Tags: Original Clinical Study Source Type: research

Prophylactic Intravitreal Bevacizumab After Plaque Radiotherapy for Uveal Melanoma: Analysis of Visual Acuity, Tumor Response, and Radiation Complications in 1131 Eyes Based on Patient Age
Purpose: The aim of this study was to determine the impact of age on radiation complications after plaque radiotherapy and prophylactic intravitreal bevacizumab for uveal melanoma. Design: Retrospective cohort study. Methods: Retrospective single-center study of plaque-irradiated uveal melanoma with prophylactic intravitreal bevacizumab at 4-month intervals from July 2000 to January 2018. Results: Of 1131 eyes in 1131 patients, age was 70 years (n = 243). Comparison by age category (70 years) revealed the oldest group presenting with greatest tumor basal diameter (11.3 vs 11.3 vs 12.1 mm, P = 0.03) and...
Source: Asia-Pacific Journal of Ophthalmology - January 1, 2020 Category: Opthalmology Tags: Original Clinical Study Source Type: research

Acquired Ocular Motor Palsy: Current Demographic and Etiological Profile
Conclusions: Acquired cranial nerve palsy has younger onset in Indian scenario. Ischemia is the most common etiology raising concerns about the health issues of young Indians. Sixth nerve is most commonly involved in all age groups. Low recovery rate in fourth nerve palsy can be attributed to traumatic etiology. (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - January 1, 2020 Category: Opthalmology Tags: Original Clinical Study Source Type: research

Quantitative and Morphological Corneal Endothelial Changes After Selective Laser Trabeculoplasty and Retinal Photocoagulation
Conclusions: SLT has measurable effects on both quantitative and morphological characteristics of the corneal endothelium, which seem to be transient. RP has fewer measurable effects, likely because, although the total laser energy is similar, it is delivered over a much longer time (3 ns versus 0.1 s). The changes observed in both procedures are minor and unlikely to be of clinical significance. (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - January 1, 2020 Category: Opthalmology Tags: Original Clinical Study Source Type: research

Effect of Metabolic Syndrome on Blood Pressure Changes During Cataract Surgery
Conclusions: Well-controlled metabolic syndrome did not affect the changes in perioperative blood pressure during cataract surgery with topical anesthesia. (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - January 1, 2020 Category: Opthalmology Tags: Original Clinical Study Source Type: research

Aspergillus Endophthalmitis: Clinical Presentations and Factors Determining Outcomes
Conclusions: Early vitrectomy and intravitreal voriconazole yielded better anatomic and functional outcomes in Aspergillus endophthalmitis. Favorable visual outcome was achieved in a fifth of the eyes and globe was salvaged in two-thirds of the eyes. (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - January 1, 2020 Category: Opthalmology Tags: Original Clinical Study Source Type: research

Factors Associated With Positive Microbial Culture in Patients With Endophthalmitis Based on Clinical Presentation and Multimodal Intraocular Sampling
Conclusions: A multimodal approach to intraocular sampling should be considered in those presenting with endophthalmitis, with both aqueous tap and vitrectomy associated with an increased probability of achieving a positive culture. (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - January 1, 2020 Category: Opthalmology Tags: Original Clinical Study Source Type: research

Endophthalmitis Management: Stain-Culture, Empirical Treatment, and Beyond
No abstract available (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - January 1, 2020 Category: Opthalmology Tags: Editorial Source Type: research

Attaining Intraocular Pressure of ≤10 mm Hg: Comparison of Tube and Trabeculectomy Surgery in Pseudophakic Primary Glaucoma Eyes
Purpose: The aim of this study is to evaluate whether trabeculectomy with antimetabolites or glaucoma drainage device (GDD) surgery is more likely to achieve an intraocular pressure (IOP) ≤10 mm Hg. Design: Retrospective, nonrandomized, cohort study of pseudophakic, primary glaucoma patients. Methods: 53 pseudophakic patients underwent trabeculectomy and 65 received GDD at the University of Florida by one surgeon between 1993 and 2015. The main outcome measures were mean IOP and percentage of patients obtaining an IOP ≤10 mm Hg for up to 5 years postoperatively. A subgroup undergoing a first time glaucoma sur...
Source: Asia-Pacific Journal of Ophthalmology - November 1, 2019 Category: Opthalmology Tags: Original Clinical Study Source Type: research

Pattern and Presentation of Vitreo-Retinal Diseases: An Analysis of Retrospective Data at a Tertiary Eye Care Center in Nepal
We examined patients presenting in a tertiary eye hospital in Nepal, focusing on information relevant to screening and management programs for vitreo-retinal (VR) disease. Design: Retrospective, cross-sectional study. Methods: We reviewed all patients presenting for the first time to the VR-clinic over 1 year. We quantified patient demography, symptoms and duration, systemic diseases, ophthalmological examinations, diagnostic investigations, and final diagnoses. Results: Of the 1905 cases, 1148 were male (60.3%). The 25th percentile of ages was 29 and 38 years for male and female, respectively; thus, female presen...
Source: Asia-Pacific Journal of Ophthalmology - November 1, 2019 Category: Opthalmology Tags: Original Clinical Study Source Type: research

A Survey of Surgical Techniques in Pterygium, Thailand 2016
Conclusions: BST and CAGT were the most selected surgical techniques for primary and recurrent pterygium, respectively. Better provision and distribution of amniotic membranes and fibrin glue along with training courses would promote the ideal surgical techniques. (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - November 1, 2019 Category: Opthalmology Tags: Original Clinical Study Source Type: research

Diffuse Outer Layer Opacification: A Novel Finding in Patients With Autosomal Recessive Bestrophinopathy
Conclusions: This is the first descriptive report of pathologic findings occurred beyond the posterior pole in patients with ARB. These mid-peripheral retinal changes potentially imply that the entirety of the RPE is affected by mutations in BEST1, as also suggested by previous electro-oculogram (EOG) findings. Such implications will be important when developing treatment trials, as past trials have focused only on the posterior pole of the RPE. (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - November 1, 2019 Category: Opthalmology Tags: Original Clinical Study Source Type: research

Latest Developments in Normal-Pressure Glaucoma: Diagnosis, Epidemiology, Genetics, Etiology, Causes and Mechanisms to Management
Normal-pressure glaucoma (NPG) is part of the spectrum of the open-angle glaucomas and morphologically characterized, as any glaucoma, by a loss of neuroretinal rim parallel to an enlargement and deepening of the optic cup, and development or enlargement of parapapillary beta zone. These morphological characteristics, in addition to the therapeutic benefit of lowering the intraocular pressure (IOP), make NPG differ from vascular-induced optic neuropathy. Based on the anatomy of the optic nerve as a cerebral fascicle, the physiological counter-pressure against the IOP is the orbital cerebrospinal fluid pressure (CSFP), with...
Source: Asia-Pacific Journal of Ophthalmology - November 1, 2019 Category: Opthalmology Tags: Review Article Source Type: research

The War on Diabetic Retinopathy: Where Are We Now?
Diabetic retinopathy (DR), a major cause of blindness in working-age adults, is emerging as a major public health issue worldwide, in particular in low- and middle-income countries (LMIC). Traditionally, the management of DR has been on tertiary-level treatment (eg, laser, anti-VEGF injections and surgery) in specialized settings by highly trained ophthalmologists on individual patients. To win the war on DR, a paradigm shift in strategic focus and resources must be made from such tertiary treatment toward primary and secondary prevention, which are broader, more impactful, and cost-effective for the larger population. The...
Source: Asia-Pacific Journal of Ophthalmology - November 1, 2019 Category: Opthalmology Tags: Review Article Source Type: research

The Rapid Transformation of Transplantation for Corneal Endothelial Diseases: An Evolution From Penetrating to Lamellar to Cellular Transplants
The cornea is the major focusing structure of the human eye and the corneal endothelium maintains the relatively dehydrated state of the cornea required for clarity. The endothelial cells respond to disease or injury by migration and cellular enlargement. Our current understanding is that there is a very limited degree of proliferative or regenerative capacity in the human corneal endothelium. Thus, corneal endothelial diseases may result in corneal edema, significantly impact vision and quality of life. Contemporary surgical transplantation options for treating moderate to advanced endothelial dysfunction include penetrat...
Source: Asia-Pacific Journal of Ophthalmology - November 1, 2019 Category: Opthalmology Tags: Review Article Source Type: research

Which Patients Would Most Likely to Benefit: MIGS or MEGS, Which One Is It?
The availability of ab interno minimally invasive glaucoma surgery (MIGS) has promoted an international interest in this procedure. Our purpose is to define the role of MIGS in the constant evolving glaucoma treatment algorithm. Current MIGS approaches to lowering intraocular pressure (IOP) include increasing trabecular outflow (iStent trabecular microbypass stent, iStent inject, Hydrus Microstent, Kahook Dual Blade goniotomy, Trabectome ab interno trabeculectomy, Excimer laser trabeculotomy, and goniotomy-assisted transluminal trabeculotomy), increasing uveoscleral outflow with suprachoroidal shunts (Cypass microstent), a...
Source: Asia-Pacific Journal of Ophthalmology - November 1, 2019 Category: Opthalmology Tags: Perspectives Source Type: research

Disruptive Innovation and Refractive IOLs: How the Game Will Change With Adjustable IOLs
The light-adjustable lens is the first Food and Drug Administration (FDA)-approved product from an entirely new category of intraocular lenses (IOLs). The 3-piece foldable silicone light-adjustable lens is implanted through a small incision after phacoemulsification. A slit-lamp-based digital light delivery device is used to adjust and then lock-in the IOL power during the first postoperative month. Up to 4.5 diopters (D) of cylindrical or spherical adjustment can be achieved. This should offer significant advantages in difficult IOL power calculation cases, such as postrefractive eyes. In addition to achieving better refr...
Source: Asia-Pacific Journal of Ophthalmology - November 1, 2019 Category: Opthalmology Tags: Perspectives Source Type: research

Keratoprosthesis: Current Choices and Future Development
Keratoprosthesis (KPro) is the last resort for corneal blindness. Boston KPro I and osteo-odonto-keratoprosthesis (OOKP) have the most favorable outcomes for their respective indications. Recently, better outcomes have been achieved for these 2 devices mainly because of improvements in postoperative care and modifications in complication management through years of experience and research. Unfortunately, some patients cannot benefit from these KPros due to lack of access to devices, trained surgeons, or both. Boston KPro I is heading toward a more affordable variation particularly for patients in developing countries. In a...
Source: Asia-Pacific Journal of Ophthalmology - November 1, 2019 Category: Opthalmology Tags: Perspectives Source Type: research

Global Blindness: The Progress We Are Making and Still Need to Make
The actual numbers of people blind or with poor vision continue to increase despite so excellent progress that is being made in reducing the prevalence or percentage of people affected. More attention is required to provide quality outcomes for cataract surgery, prevent and manage myopia, detect and treat diabetic retinopathy, glaucoma, and age-related macular degeneration (AMD). Although more ophthalmologists are needed to provide this eye care, it is important that ophthalmologists work in effective teams with allied eye health personal to be able to meet the community needs. (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - November 1, 2019 Category: Opthalmology Tags: Perspectives Source Type: research

Pterygium: Surgical Techniques and Choices
No abstract available (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - November 1, 2019 Category: Opthalmology Tags: Editorial Source Type: research

Normal Pressure Glaucoma: The Challenge in Asia and the Scientific Contributions from Asia
No abstract available (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - November 1, 2019 Category: Opthalmology Tags: Editorial Source Type: research

Promising Artificial Intelligence–Machine Learning–Deep Learning Algorithms in Ophthalmology: Erratum
No abstract available (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - September 1, 2019 Category: Opthalmology Tags: Erratum Source Type: research

Future Developments in SMILE: Higher Degree of Myopia and Hyperopia
In this study, we review the published clinical outcomes of high myopia correction and exploration in hyperopia correction. Results have suggested that SMILE has acceptable outcomes in correction for high myopia (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - September 1, 2019 Category: Opthalmology Tags: Review Article Source Type: research

Enhancement Options After Myopic Small-Incision Lenticule Extraction (SMILE): A Review
Conclusions: Refractive enhancement after SMILE is currently mostly performed by surface ablation, CIRCLE cap-to-flap conversion or thin-flap LASIK, which all offer safety and efficacy comparable to LASIK retreatments. In this review, a detailed overview over each method, its technical aspects, and specific advantages and disadvantages is given. (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - September 1, 2019 Category: Opthalmology Tags: Review Article Source Type: research

Dry Eyes After SMILE
Dry eyes is one of the most common complications after laser vision correction. Small incision lenticule extraction (SMILE) is a flapless procedure with a smaller corneal incision, less corneal nerves are transected during, making it theoretically less prone to dry eyes. Both SMILE and femtosecond-laser-assisted in situ keratomileusis (FS-LASIK) induce a transient worsening in dry eye parameters, but there is evidence showing that SMILE holds promises to have fewer negative impacts on the ocular surface parameters and allow an earlier recovery. SMILE-treated eyes may also have shown less corneal denervation and better corn...
Source: Asia-Pacific Journal of Ophthalmology - September 1, 2019 Category: Opthalmology Tags: Review Article Source Type: research

Astigmatism Correction Using SMILE
Small incision lenticule extraction (SMILE) was introduced in the recent decade for the treatment of myopia and myopic astigmatism. This flap-free technique has a high efficacy and safety profile and also carries potential advantages over laser in situ keratomileusis such as a better corneal biomechanical stability, reduction in dry eyes rate, and the avoidance of flap complications. However, there have been concerns regarding the precision of astigmatism correction that undercorrection has been reported to be apparent. Various factors that affect astigmatism correction have been identified in the literature. The purpose o...
Source: Asia-Pacific Journal of Ophthalmology - September 1, 2019 Category: Opthalmology Tags: Review Article Source Type: research

Review on Centration, Astigmatic Axis Alignment, Pupil Size and Optical Zone in SMILE
The advent of “flapless” small-incision lenticule extraction (SMILE), employing all-in-one technology, has resulted in a revolutionary breakthrough in refractive surgeries. SMILE has been gaining popularity due to fewer potential complications, such as postoperative dry eyes and greater biomechanical stability, etc. However, attention must be given to 1) the centration on the corneal vertex, 2) the proper alignment of the astigmatic axis, and 3) the relationship between pupil size and treatment diameter, to achieve good SMILE results. There is no pupil-tracking system to ascertain the accuracy of centration dur...
Source: Asia-Pacific Journal of Ophthalmology - September 1, 2019 Category: Opthalmology Tags: Review Article Source Type: research

Comparing Patient-Reported Outcomes of Laser In Situ Keratomileusis and Small-Incision Lenticule Extraction: A Review
Conclusions: Future LASIK-SMILE comparative studies utilizing standardized validated questionnaires for patient-reported outcome measures with longer follow-up durations would be a welcome contribution to this important aspect of refractive surgery. (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - September 1, 2019 Category: Opthalmology Tags: Review Article Source Type: research

History and Results; Indications and Contraindications of SMILE, Compared With LASIK
Small incision lenticule extraction (SMILE) is a new paradigm for refractive surgery, and was first performed by Sekundo and Blum in 2008. It uses only a femtosecond laser to carve out a lenticule within the corneal stroma, and then achieves refractive correction by extracting the lenticule through a small incision. A number of studies have shown that SMILE leads to stable and efficacious outcomes, combined with high safety. Long-term studies also indicate that SMILE has excellent outcomes combined with high safety. Although relatively safe, SMILE can have some intraoperative and postoperative complications, including suct...
Source: Asia-Pacific Journal of Ophthalmology - September 1, 2019 Category: Opthalmology Tags: Review Article Source Type: research

Posterior Scleral Reinforcement to Prevent Progression of High Myopia
Conclusions: PSR, is safe and effective to slow down myopia progression, especially for high myopia. (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - September 1, 2019 Category: Opthalmology Tags: Review Article Source Type: research

Low-Concentration Atropine Eye Drops for Myopia Progression
Conclusions: Low concentration atropine is effective in myopia control. The widespread use of low-concentration atropine, especially in East Asia, may help prevent the myopia progression for the high-risk children. Further investigations on the rebound phenomenon following drops cessation, and longer-term individualized treatment approach should be warranted. (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - September 1, 2019 Category: Opthalmology Tags: Review Article Source Type: research

Myopia: Anatomic Changes and Consequences for Its Etiology
The process of emmetropization is the adjustment of the length of the optical axis to the given optical properties of the cornea and lens after the end of the second year of life. Up to the end of the second year of life, the eye grows spherically. Axial elongation in the process of emmetropization after the second year of life is associated with a thinning of the retina and a reduced density of retinal pigment epithelium (RPE) cells in the equatorial and retroequatorial region, and a thinning of the choroid and sclera, starting at the equator and being most marked at the posterior pole. In contrast, retinal thickness and ...
Source: Asia-Pacific Journal of Ophthalmology - September 1, 2019 Category: Opthalmology Tags: Review Article Source Type: research

Will SMILE Become the New Benchmark of Corneal Laser Refractive Surgery?
No abstract available (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - September 1, 2019 Category: Opthalmology Tags: Editorial Source Type: research

AcrySof IQ PanOptix Intraocular Lens Versus Extended Depth of Focus Intraocular Lens and Trifocal Intraocular Lens: A Clinical Overview
AcrySof IQ PanOptix Model TFNT00 (Alcon Laboratories, Fort Worth, TX) is a 1-piece aspheric hydrophobic presbyopia-correcting intraocular lens (IOL) launched in 2015. Unlike traditional trifocal IOLs that usually have an intermediate focal point of 80 cm, the PanOptix IOL is designed to have an intermediate focal point of 60 cm (arms-length), a more natural and comfortable working distance to perform functional tasks on computers, laptops, mobiles, among others. The non-apodized PanOptix IOL uses the ENhanced LIGHT ENergy (ENLIGHTEN; Alcon Laboratories, Fort Worth, TX) optical technology that provides high (88%) utiliz...
Source: Asia-Pacific Journal of Ophthalmology - July 1, 2019 Category: Opthalmology Tags: Review Article Source Type: research

Compared Near-Vision Testing With the Nintendo 3DS PDI Check Game on the Thai–Burma Border
Background: A near vision game has been developed for the autostereoscopic screen of the Nintendo 3DS console. Ease of use and time for testing by non–English-speaking patients was not known. Methods: Adult and pediatric patients in a remote Burma clinic were compared with US military staff with each performing conventional near acuity, Stereo Fly, and Ishihara color in addition to PDI Check game, so results could be correlated and timed. Results: Seventeen Burma adults (aged 19–58), 20 Burma children (aged 7–15), and 14 US military staff (aged 21–36) completed the testing. Conventional test...
Source: Asia-Pacific Journal of Ophthalmology - July 1, 2019 Category: Opthalmology Tags: Original Clinical Study Source Type: research

Effect of Demographic Variables on the Regional Corneal Pachymetry
Conclusions: Different corneal sectors may interact heterogeneously with patient-related characteristics. This may provide incentive to evaluate whole-corneal thickness as a distinct parameter for clinical identification of disease processes. (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - July 1, 2019 Category: Opthalmology Tags: Original Clinical Study Source Type: research

Effect of Insulin-Like Growth Factor-1 on Diabetic Retinopathy in Pubertal Age Patients With Type 1 Diabetes
Purpose: The aims of this study were to correlate diabetic retinopathy (DR) changes with insulin-like growth factor 1 (IGF-1) levels in patients with type 1 diabetes of pubertal age group and to correlate the level of retinopathy with IGF-1 levels. Methods: This cross-sectional study was done over 2 years and involved patients with type 1 diabetes of age 8 to 25 years. Patients presenting to Ophthalmology OPD and inpatient department along with active recruitment from old pediatrics and endocrinology records were taken for the study. Fasting serum IGF-1 was calculated using enzyme-linked immunosorbent assay technique....
Source: Asia-Pacific Journal of Ophthalmology - July 1, 2019 Category: Opthalmology Tags: Original Clinical Study Source Type: research

Choroidal Hyperreflective Foci: A Novel Spectral Domain Optical Coherence Tomography Biomarker in Eyes With Diabetic Macular Edema
Conclusions: The present study describes HCF as novel prognostic SDOCT biomarker in DME whose presence denotes poor visual acuity. Further longitudinal studies are required to substantiate our findings. (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - July 1, 2019 Category: Opthalmology Tags: Original Clinical Study Source Type: research

Intravitreal Ranibizumab With Panretinal Photocoagulation Followed by Trabeculectomy Versus Visco-Trabeculotomy in Management of Neovascular Glaucoma
Conclusions: Both VT and Trab-MMC groups are effective in reducing the IOP in cases of NVG after control of neovascularization with anti-vascular endothelial growth factor and pan retinal photocoagulation. (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - July 1, 2019 Category: Opthalmology Tags: Original Clinical Study Source Type: research

Factors Affecting Pupil Reactivity After Cycloplegia in Asian Children
Purpose: The aim of this study was to evaluate the factors affecting cycloplegia, as determined by pupil reactivity, in Asian children. Design: Prospective observational study. Methods: Two-hundred sixty-eight children, aged 2 to 12 years, requiring cycloplegic refraction, were recruited. Nurses instilled 2 to 3 cycles of eye drops consisting of cyclopentolate 1%, tropicamide 0.5%, and phenylephrine 2.5%, and recorded the child's level of cooperation. Optometrists recorded pupil reactivity after the last cycle. Multivariate analysis determined factors affecting pupil reactivity including age, sex, race, number of e...
Source: Asia-Pacific Journal of Ophthalmology - July 1, 2019 Category: Opthalmology Tags: Original Clinical Study Source Type: research

Uveal Metastasis Based on Patient Sex in 2214 Tumors of 1111 Patients. A Comparison of Female Versus Male Clinical Features and Outcomes
Background: Lacking in previous studies on uveal metastasis is a robust statistical comparison of patient demographics, tumor features, and overall survival based on patient sex. Objective: The aim of this study was to evaluate demographics, clinical features, and overall survival of patients with uveal metastasis based on sex. Method: This is a retrospective analysis. All patients were evaluated on the Ocular Oncology Service, Wills Eye Hospital, PA between January 1, 1974 and June 1, 2017. Results: A total of 2214 uveal metastases were diagnosed in 1310 eyes of 1111 consecutive patients. A comparison (female v...
Source: Asia-Pacific Journal of Ophthalmology - July 1, 2019 Category: Opthalmology Tags: Original Clinical Study Source Type: research

Factors Predictive of Subretinal Fluid Resolution in Coats Disease: Analysis of 177 Eyes in 177 Patients at a Single Center
Purpose: The aim of this study was to investigate factors predictive of subretinal fluid (SRF) resolution in Coats disease. Design: Retrospective cohort study. Methods: Institutional review board-approved review of patients diagnosed with Coats disease demonstrating SRF (stage 3–5) at a single center from November 1973 to July 2018 with comparison of eyes that had resolution of SRF to those in which SRF persisted. Results: There were 177 cases (154 males, 87%) of Coats disease diagnosed at a mean age of 8 years. After a mean follow-up of 62 months, SRF resolved in 110 (62%) and persisted in 67 (38%) eyes. ...
Source: Asia-Pacific Journal of Ophthalmology - July 1, 2019 Category: Opthalmology Tags: Original Clinical Study Source Type: research

Performance of a New-Generation Extended Depth of Focus Intraocular Lens—A Prospective Comparative Study
Purpose: The aim was to study the visual performance of a new refractive extended depth of focus (EDOF) intraocular lens (IOL). Design: Prospective, comparative study. Methods: Consenting patients with age-related cataract willing for bilateral cataract surgery within 2 weeks were implanted with the Supraphob EDOF IOL and those willing for 1 eye surgery were implanted with a monofocal IOL. The uncorrected and best-corrected distance, intermediate and near visual acuity, and contrast sensitivity were evaluated at 1 and 3 months postoperatively. We also inquired about glare, halos, difficulties in night driving, requ...
Source: Asia-Pacific Journal of Ophthalmology - July 1, 2019 Category: Opthalmology Tags: Original Clinical Study Source Type: research

Ocular Toxoplasmosis in a Tertiary Referral Center in Sydney Australia—Clinical Features, Treatment, and Prognosis
Conclusions: Patients with ocular toxoplasmosis had fewer recurrences compared with other published series and had better visual recovery. The majority of patients received clindamycin and oral prednisolone which were well tolerated with pyrimethazine and sulfadiazine reserved for those with macula-involving disease. (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - July 1, 2019 Category: Opthalmology Tags: Original Clinical Study Source Type: research

Variability of Central Corneal Thickness Measurements—Comparing Zeiss IOL Master and Tomey Corneal Specular Microscope
Purpose: The aim of this study was to compare the intraobserver repeatability and agreement of central corneal thickness (CCT) measurements by 2 commonly available instruments, Zeiss IOL Master 700 (SS-OCT-based optical biometry device) and Tomey corneal specular microscope EM-3000 (Noncontact specular microscopy). Design: Retrospective study. Methods: This is a retrospective analysis of data from routine clinical practice in which preoperative CCT measurements of 105 patients scheduled for cataract surgery were analyzed. Two consecutive CCT measurements were measured using Zeiss IOL Master 700 and Tomey corneal sp...
Source: Asia-Pacific Journal of Ophthalmology - July 1, 2019 Category: Opthalmology Tags: Original Clinical Study Source Type: research

Presbyopic Lenses: Evidence, Masquerade News, and Fake News
No abstract available (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - July 1, 2019 Category: Opthalmology Tags: Editorial Source Type: research

Promising Artificial Intelligence-Machine Learning-Deep Learning Algorithms in Ophthalmology
Abstract: The lifestyle of modern society has changed significantly with the emergence of artificial intelligence (AI), machine learning (ML), and deep learning (DL) technologies in recent years. Artificial intelligence is a multidimensional technology with various components such as advanced algorithms, ML and DL. Together, AI, ML, and DL are expected to provide automated devices to ophthalmologists for early diagnosis and timely treatment of ocular disorders in the near future. In fact, AI, ML, and DL have been used in ophthalmic setting to validate the diagnosis of diseases, read images, perform corneal topographic ma...
Source: Asia-Pacific Journal of Ophthalmology - May 1, 2019 Category: Opthalmology Tags: Review Article Source Type: research