Asia-Pacific Journal of Ophthalmology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Biologic Drugs for the Treatment of Noninfectious Uveitis
The management of noninfectious uveitis is constantly evolving. A new “biologic era” in treatment began after the effectiveness of tumor necrosis factor-alpha blocking drugs was demonstrated in rheumatologic inflammatory diseases. The goal of specific immunomodulation with a biologic drug is to target inflammation at the molecular level with a low rate of serious adverse events. The purpose of this review is to summarize current knowledge of biologic drugs in the treatment of noninfectious uveitis by describing clinical studies and recent pharmacological developments. (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - January 1, 2021 Category: Opthalmology Tags: Review Article Source Type: research

Big Data-Based Epidemiology of Uveitis and Related Intraocular Inflammation
Large administrative health databases, nationwide surveys, and the widespread adoption of electronic medical records have led to an increasing availability of health-related data on ocular inflammatory disease, allowing us to elucidate the real-world epidemiology of uveitis and examine patient and systems-level risk factors for the incidence of specific etiologies of uveitis and its complications. Despite the many advantages to using big databases, there are also limitations that clinicians must be aware of when making conclusions and extrapolating to the general population, such as the lack of standardization of nomenclat...
Source: Asia-Pacific Journal of Ophthalmology - January 1, 2021 Category: Opthalmology Tags: Review Article Source Type: research

Myopic Traction Maculopathy: A New Perspective on Classification and Management
Myopic traction maculopathy (MTM) is a complex disease affecting approximately 30% of eyes with pathologic myopia. A review of the history of treatment of MTM with success rates and limitations of different surgical techniques are reported. The pathogenesis, the definition and the management were clarified in a recent study(cit). The MTM Staging System (MSS) table summarizes all the stages of MTM offering insights on the pathogenesis and natural evolution of the disease. Guidelines of management of MTM were therefore proposed, but customized for each stage. Initial stages 1a and 2a, which define maculoschisis in t...
Source: Asia-Pacific Journal of Ophthalmology - January 1, 2021 Category: Opthalmology Tags: Review Article Source Type: research

Digital Technology for AMD Management in the Post-COVID-19 New Normal
Conclusions: Digitalization strategies and developments are currently ongoing and underway to ensure early detection, stability and visual improvement in patients suffering from AMD in this COVID-19 era. This may set a precedence for the post COVID-19 new normal where digital platforms may be routine, standard and expected in healthcare delivery. (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - January 1, 2021 Category: Opthalmology Tags: Review Article Source Type: research

Role of Vital Dyes in Chromovitrectomy
Chromovitrectomy, the intraocular application of dyes to assist visualization of preretinal tissues during vitreoretinal surgery, was introduced to avoid ocular complications related to internal limiting membrane peeling, inadequate removal of the vitreous, and incomplete removal of epiretinal membranes. Since 2000, chromovitrectomy has become a popular approach among vitreoretinal specialists. The first vital dye used in chromovitrectomy, indocyanine green, facilitated identification of the fine and transparent internal limiting membrane. Following indocyanine green, trypan blue was introduced to identify epiretinal membr...
Source: Asia-Pacific Journal of Ophthalmology - January 1, 2021 Category: Opthalmology Tags: Review Article Source Type: research

Optical Coherence Tomography Angiography in Diabetes
The introduction of optical coherence tomography angiography (OCTA) has significantly improved our knowledge on the ocular vascular alterations occurring in diabetes. In this article, we will provide a review of the prominent OCTA findings in diabetes. In details, OCTA demonstrated that both the retinal vessels and the choriocapillaris are affected in diabetic subjects. The recent employment of widefield technology and a 3-dimensional (3D) visualization in OCTA imaging are also discussed. (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - January 1, 2021 Category: Opthalmology Tags: Review Article Source Type: research

OCT-A in the Management of Vitreoretinal Diseases and Surgery
Optical coherence tomography angiography is a relatively new noninvasive technique that is changing our approach in the management of several retinal diseases such as neovascular age-related macular degeneration, occlusive retinal diseases, or diabetic retinopathy, but it could also be useful in nonprimary vascular retinal pathologies such as vitreoretinal interface surgical disorders. In idiopathic vitreoretinal interface disorders and surgical retinal diseases, the study of vascular involvement, not commonly assessed by invasive methods, could be useful to reveal specific vascular abnormalities. Such information may b...
Source: Asia-Pacific Journal of Ophthalmology - January 1, 2021 Category: Opthalmology Tags: Review Article Source Type: research

Creating an Ocular Biofactory: Surgical Approaches in Gene Therapy for Acquired Retinal Diseases
Gene therapy offers the potential to treat inherited retinal disorders and deliver sustained therapy for acquired retinal diseases. In the latter case, host cells can be harnessed to produce non-native proteins that have beneficial properties, such as antivascular endothelial growth factor activity, transforming the eye into an ocular “biofactory.” Several gene therapy programs have entered clinical testing for delivery to the vitreous, subretinal, and suprachoroidal space. Improved viral vectors and refined surgical techniques are critical to successful delivery of therapeutic products to the target tissue. In this re...
Source: Asia-Pacific Journal of Ophthalmology - January 1, 2021 Category: Opthalmology Tags: Review Article Source Type: research

Editorial on Uveitis and Intraocular Inflammations
No abstract available (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - January 1, 2021 Category: Opthalmology Tags: Editorial Source Type: research

Advances in Surgery for Vitreoretinal Disease
No abstract available (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - January 1, 2021 Category: Opthalmology Tags: Editorial Source Type: research

Lamellar Keratoplasty for Advanced Keratoconus
This article reviews the various surgical techniques in ALK with its clinical outcomes in advanced keratoconus. (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - November 1, 2020 Category: Opthalmology Tags: Review Article Source Type: research

Corneal Stroma Regeneration: New Approach for the Treatment of Cornea Disease
Corneal grafting is one of the most common forms of human tissue transplantation. The corneal stroma is responsible for many characteristics of the cornea. For these reasons, an important volume of research has been made to replicate the corneal stroma in the laboratory to find an alternative to classical corneal transplantation techniques. There is an increasing interest today in cell therapy of the corneal stroma using induced pluripotent stem cells or mesenchymal stem cells since these cells have shown to be capable of producing new collagen within the host stroma and even to improve its transparency. The first cl...
Source: Asia-Pacific Journal of Ophthalmology - November 1, 2020 Category: Opthalmology Tags: Review Article Source Type: research

Bowman Layer Transplantation—A Review
This article reviews the history of BL transplantation and recent developments, and anticipated next steps for the procedure. (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - November 1, 2020 Category: Opthalmology Tags: Review Article Source Type: research

Corneal Cross-Linking for Keratoconus: Current Knowledge and Practice and Future Trends
Corneal collagen cross-linking (CXL) with riboflavin is an accepted universal standard of care for our keratoconus patients with progressive disease. It has been a game changer in how we manage keratoconus. Early diagnosis and treatment is essential in paediatric patients as younger patients progress more rapidly and have poorer transplant outcomes. There is an ongoing debate around standard, accelerated, and transepithelial protocols of CXL, the role of CXL, and the combination of laser refractive surgery. Future developments will improve CXL safety and efficacy and the scope of utilization, but we must be careful not to ...
Source: Asia-Pacific Journal of Ophthalmology - November 1, 2020 Category: Opthalmology Tags: Review Article Source Type: research

The Enigma of Environmental Factors in Keratoconus
Keratoconus is an ectatic disorder with highly complex and varied causes including genetic variations and environmental factors. Its prevalence varies widely between regions and countries. Many environmental factors have been proposed to be associated with keratoconus, but the interpretation of their individual contributions is difficult due to the presence of many confounding variables. The current literature was reviewed to evaluate the strength of the associations and the causative effects of environmental factors on keratoconus. Ethnicity and consanguinity have been revealed as important determinants for geographical v...
Source: Asia-Pacific Journal of Ophthalmology - November 1, 2020 Category: Opthalmology Tags: Review Article Source Type: research