Correction to: Morphology of the sulcus of the caudate process (Rouviere ’s sulcus) in a Greek population and a systematic review with meta-analysis
(Source: Anatomical Science International)
Source: Anatomical Science International - October 17, 2021 Category: Anatomy Source Type: research

Molecular dynamics of estrogen-related receptors and their regulatory proteins: roles in transcriptional control for endocrine and metabolic signaling
AbstractEstrogen-related receptor (ERR) is a member of the nuclear receptor (NR) superfamily and has three subtypes α, β, and γ. Despite their strong homology with estrogen receptor (ER) α, ERRs cannot accommodate endogenous hormones. However, they are able to regulate gene expression without ligand binding. ERRα and ERRγ orchestrate the expression of genes involved in bioenergetic pathways, while ERRβ con trols placental development and stem cell maintenance. Evidence from recent studies, including clinical research, has also demonstrated close associations of ERRs with the pathophysiology of hormone-related cancer...
Source: Anatomical Science International - October 5, 2021 Category: Anatomy Source Type: research

Unknown variant of the accessory subscapularis muscle?
AbstractActing in medial rotation of the arm, the subscapularis (SM) is the most powerful and largest muscle of the rotator cuff. It is morphologically variable, especially in the number of tendons, place of insertion, and number of bellies, and it is sometimes fused with another muscle. An accessory subscapularis muscle (ASM) is among the morphological variations of the SM, but it is a really rare variant. The present case describes a very rare ASM that is divided into proximal tendinous attachment, intermediate fleshy muscular belly and distal tendinous attachment. Its origin is located on the lateral border of the scapu...
Source: Anatomical Science International - September 30, 2021 Category: Anatomy Source Type: research

The prevalence and distribution of sternalis muscle: a meta-analysis of published literature of the last two hundred  years
AbstractThe sternalis muscle (SM) is an anatomical variant that lies subcutaneously and is superficial to the pectoralis major muscle or sternum. The present meta-analysis was conducted to analyze the prevalence, anatomical features, and variance of the SM in different population. In total, 98 studies were included for this meta-analysis. Eighty-two studies dealt with adult subjects, and sixteen studies with fetuses. The worldwide prevalence of SM was observed to be 6% or 0.06 [0.05 –0.7, 95% CI] in 27,470 adults, whereas it was 0.29 [0.20–0.39, 95% CI] in 673 fetuses. In 259 anencephalic fetuses, the prevalence was 44...
Source: Anatomical Science International - September 30, 2021 Category: Anatomy Source Type: research

Unknown variant of the accessory subscapularis muscle?
AbstractActing in medial rotation of the arm, the subscapularis (SM) is the most powerful and largest muscle of the rotator cuff. It is morphologically variable, especially in the number of tendons, place of insertion, and number of bellies, and it is sometimes fused with another muscle. An accessory subscapularis muscle (ASM) is among the morphological variations of the SM, but it is a really rare variant. The present case describes a very rare ASM that is divided into proximal tendinous attachment, intermediate fleshy muscular belly and distal tendinous attachment. Its origin is located on the lateral border of the scapu...
Source: Anatomical Science International - September 30, 2021 Category: Anatomy Source Type: research

The prevalence and distribution of sternalis muscle: a meta-analysis of published literature of the last two hundred  years
AbstractThe sternalis muscle (SM) is an anatomical variant that lies subcutaneously and is superficial to the pectoralis major muscle or sternum. The present meta-analysis was conducted to analyze the prevalence, anatomical features, and variance of the SM in different population. In total, 98 studies were included for this meta-analysis. Eighty-two studies dealt with adult subjects, and sixteen studies with fetuses. The worldwide prevalence of SM was observed to be 6% or 0.06 [0.05 –0.7, 95% CI] in 27,470 adults, whereas it was 0.29 [0.20–0.39, 95% CI] in 673 fetuses. In 259 anencephalic fetuses, the prevalence was 44...
Source: Anatomical Science International - September 30, 2021 Category: Anatomy Source Type: research

The behavior and functions of embryonic microglia
AbstractMicroglia are the resident immune cells of the central nervous system. Microglial progenitors are generated in the yolk sac during the early embryonic stage. Once microglia enter the brain primordium, these cells colonize the structure through migration and proliferation during brain development. Microglia account for a minor population among the total cells that constitute the developing cortex, but they can associate with many surrounding neural lineage cells by extending their filopodia and through their broad migration capacity. Of note, microglia change their distribution in a stage-dependent manner in the dev...
Source: Anatomical Science International - September 19, 2021 Category: Anatomy Source Type: research

Protective and therapeutic effect of (S)-ginsenoside F1 on peripheral nerve degeneration targeting Schwann cells: a pharmaco-neuroanatomical approach
AbstractDamaged peripheral nerves undergo peripheral neurodegenerative processes that are essential for the nerve regeneration. Peripheral neurodegenerative diseases, including diabetic peripheral neuropathy, are induced by irreversible nerve damage caused by abnormal peripheral nerve degeneration. However, until now, there have been no effective therapeutic treatments for these diseases. Ginsenosides are the most pharmacologically active compounds inPanax ginseng, and are being actively studied. Ginsenosides have a variety of effects, including neuroprotective, antioxidative, anti-cytotoxic, and anti-inflammatory effects....
Source: Anatomical Science International - September 17, 2021 Category: Anatomy Source Type: research

Morphology of the sulcus of the caudate process (Rouviere ’s sulcus) in a Greek population and a systematic review with meta-analysis
In conclusion, the sulcus of the caudate process is a very helpful anatomical landmark in hepatectomy and laparoscopic cholecystectomy and can be identified in the majority of patients. However, various classifications for the morphological variants and diverse terminology cause discrepancy in the literature and create the need for a single classification system. The proposed 3-tier classification (groove, slit, scar) is simple and easy to remember and avoids ambiguous nomenclature. (Source: Anatomical Science International)
Source: Anatomical Science International - September 17, 2021 Category: Anatomy Source Type: research

Protective and therapeutic effect of (S)-ginsenoside F1 on peripheral nerve degeneration targeting Schwann cells: a pharmaco-neuroanatomical approach
AbstractDamaged peripheral nerves undergo peripheral neurodegenerative processes that are essential for the nerve regeneration. Peripheral neurodegenerative diseases, including diabetic peripheral neuropathy, are induced by irreversible nerve damage caused by abnormal peripheral nerve degeneration. However, until now, there have been no effective therapeutic treatments for these diseases. Ginsenosides are the most pharmacologically active compounds inPanax ginseng, and are being actively studied. Ginsenosides have a variety of effects, including neuroprotective, antioxidative, anti-cytotoxic, and anti-inflammatory effects....
Source: Anatomical Science International - September 17, 2021 Category: Anatomy Source Type: research