The Effect of Smoking on the Association between Long-Term Alcohol Consumption and Dyslipidemia in a Middle-Aged and Older Population
ConclusionSmoking crucially confounds the association between long-term alcohol consumption and dyslipidemia, particularly in hypertriglyceridemia and hypercholesterolemia. (Source: Alcohol and Alcoholism)
Source: Alcohol and Alcoholism - June 26, 2020 Category: Addiction Source Type: research
Did the General Population in Germany Drink More Alcohol during the COVID-19 Pandemic Lockdown?
In his review entitled ‘Are patients with alcohol use disorders (AUDs) at increased risk for coronavirus disease 2019 (COVID-19) infection?’,Testino (2020) examines the effect of alcohol consumption on the risk for a severe illness in case of infection by the new coronavirus 2019 [severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)]. There are relatively good data on the interaction between SARS-CoV-2 and AUD in the existing literature, suggesting that patients suffering from an AUD oralcoholic liver disease are at a greater risk of a severe course of SARS-CoV-2.Testino (2020) suggested therefore that these pa...
Source: Alcohol and Alcoholism - June 19, 2020 Category: Addiction Source Type: research
What We Talk About When We Talk About Binge Drinking: Towards an Integrated Conceptualization and Evaluation
AbstractRationaleBinge drinking (BD), characterized by recurring alternations between intense intoxication episodes and abstinence periods, is the most frequent alcohol consumption pattern in youth and is growing in prevalence among older adults. Many studies have underlined the specific harmful impact of this habit by showing impaired abilities in a wide range of cognitive functions among binge drinkers, as well as modifications of brain structure and function.AimsSeveral controversies and inconsistencies currently hamper the harmonious development of the field and the recognition of BD as a specific alcohol consumption p...
Source: Alcohol and Alcoholism - June 19, 2020 Category: Addiction Source Type: research
Mortality After Extrahepatic Gastrointestinal and Abdominal Wall Surgery in Patients With Alcoholic Liver Disease: A Systematic Review and Meta-Analysis
ConclusionPostoperative in-hospital mortality is high in patients with liver disease and ALD in particular. However, the currently available evidence on ALD is limited and precludes definitive conclusions on postoperative mortality risk. (Source: Alcohol and Alcoholism)
Source: Alcohol and Alcoholism - June 19, 2020 Category: Addiction Source Type: research
Perceived Gender Match and Accepting Alcohol Offers From Peers in Emerging Adulthood
ConclusionIn this sample, we found that men have a higher BW for alcohol than women and that trans identified persons are at increased risk for alcohol misuse. These findings support the need for more research examining the effect of gender identity on patterns of alcohol use and decision-making in mixed-gender contexts for emerging adults. (Source: Alcohol and Alcoholism)
Source: Alcohol and Alcoholism - June 17, 2020 Category: Addiction Source Type: research
Behavioral Screening of Alcohol Effects and Individual Differences in Zebrafish (Danio rerio)
ConclusionsOur results corroborate with previous findings that alcohol affects the behavioral profiles of zebrafish differently, with bold animals apparently more resistant to these changes. (Source: Alcohol and Alcoholism)
Source: Alcohol and Alcoholism - June 13, 2020 Category: Addiction Source Type: research
Make Mission Impossible Feasible: The Experience of a Multidisciplinary Team Providing Treatment for Alcohol Use Disorder to Homeless Individuals
ConclusionPatients experiencing homelessness may benefit from a multidisciplinary treatment program for AUD. Strategies able to facilitate and support their social reintegration and housing can improve treatment outcomes. (Source: Alcohol and Alcoholism)
Source: Alcohol and Alcoholism - June 13, 2020 Category: Addiction Source Type: research
Chronic Alcohol Intake Exacerbates Cardiac Dysfunction After Myocardial Infarction
ConclusionsOur study demonstrated that chronic daily alcohol exposure exacerbated MI-induced cardiac dysfunction, which is related to promoted myocardial fibrosis and inhibited mitochondrial function. (Source: Alcohol and Alcoholism)
Source: Alcohol and Alcoholism - June 13, 2020 Category: Addiction Source Type: research
Racial/Ethnic Disparities in the Relationship of Alcohol-Related Injury and Perceived Driving Under the Influence from Hours of Exposure to High Blood Alcohol Concentration: Data From Four US National Alcohol Surveys (2000 –2015)
ConclusionsFindings showed racial/ethnic differences in risk of alcohol-related injury and perceived DUI from hours of exposure to elevated BAC. Risk increased at relatively low levels of exposure to a BAC ≥ 0.08, especially for whites, highlighting the importance of preventive efforts to reduce harmful outcomes for moderate drinkers. (Source: Alcohol and Alcoholism)
Source: Alcohol and Alcoholism - June 10, 2020 Category: Addiction Source Type: research
The Impact of Appetite-Regulating Neuropeptide Leptin on Alcohol Use, Alcohol Craving and Addictive Behavior: A Systematic Review of Preclinical and Clinical Data
ConclusionsIn this review of preclinical and clinical data, we assess the role of leptin in alcohol use and the development and maintenance of an alcohol use disorder, alcohol craving and relapse. Integrating the existing preclinical and clinical data on leptin may reveal new and innovative targets for the treatment of substance use disorders in the future. (Source: Alcohol and Alcoholism)
Source: Alcohol and Alcoholism - June 3, 2020 Category: Addiction Source Type: research
Why Is Per Capita Consumption Underestimated in Alcohol Surveys? Results from 39 Surveys in 23 European Countries
ConclusionThe results reiterate that alcohol survey data should not be used to compare or estimate aggregate consumption levels, which may be better reflected by statistics on recorded or total per capita consumption. (Source: Alcohol and Alcoholism)
Source: Alcohol and Alcoholism - June 3, 2020 Category: Addiction Source Type: research
Alcohol, Alcoholic Beverages and Risk of Esophageal Cancer by Histological Type: A Dose –Response Meta-Analysis of Observational Studies
ConclusionsThis meta-analysis suggests that alcohol intake might significantly increase the incidence of EC, especially for ESCC. (Source: Alcohol and Alcoholism)
Source: Alcohol and Alcoholism - June 2, 2020 Category: Addiction Source Type: research
Spontaneous Early Withdrawal Behaviors after Chronic 24-hour Free-Choice Access to Ethanol
ConclusionThis study confirms that P rats meet the animal model criterion for ethanol-associated dependence, without a reliance on either behavioral (limited fluid access) or pharmacological (seizure threshold manipulation) challenges. (Source: Alcohol and Alcoholism)
Source: Alcohol and Alcoholism - June 2, 2020 Category: Addiction Source Type: research
Hyperalgesia after a Drinking Episode in Young Adult Binge Drinkers: A Cross-Sectional Study
ConclusionsThis is the first study to show that alcohol withdrawal-associated muscle hyperalgesia may occur in healthy episodic binge drinkers with only 2 –3 years of drinking history, and epinephrine may play a role in binge drinking-associated hyperalgesia. (Source: Alcohol and Alcoholism)
Source: Alcohol and Alcoholism - June 1, 2020 Category: Addiction Source Type: research
Probenecid Reduces Alcohol Drinking in Rodents. Is Pannexin1 a Novel Therapeutic Target for Alcohol Use Disorder?
ConclusionsThese results raise the possibility that pannexin1 is a novel therapeutic target for the treatment of AUD. The clinical use of probenecid has been found to be generally safe, suggesting that it can be a candidate for drug repositioning for the treatment of AUD. (Source: Alcohol and Alcoholism)
Source: Alcohol and Alcoholism - September 19, 2019 Category: Addiction Source Type: research
