Catalpol antagonizes LPS-mediated inflammation and promotes osteoblast differentiation through the miR-124-3p/DNMT3b/TRAF6 axis
CONCLUSION: Catalpol antagonizes LPS-mediated inflammation and suppressive osteoblast differentiation via controlling the miR-124-3p/DNMT3b/TRAF6 axis.PMID:38039796 | DOI:10.1016/j.acthis.2023.152118 (Source: Acta Histochemica)
Source: Acta Histochemica - December 1, 2023 Category: Biochemistry Authors: Pan Zhang Qun Feng Wenxiao Chen Xizhuang Bai Source Type: research
Delineation of the healthy rabbit tongue by immunohistochemistry - A technical note
Acta Histochem. 2023 Nov 30;126(1):152127. doi: 10.1016/j.acthis.2023.152127. Online ahead of print.ABSTRACTIn the oral cavity the tongue is an important muscular organ that supports the swallowing of food and liquids. It is responsible for the sense of taste, based on the many different taste buds it contains. Research in the field of tongue diseases demands for suitable preclinical models. The healthy rabbit tongue may therefore serve as baseline and reference for the pathological situation. With this consideration, we covered the fixation and histological stainings as well as the immunohistochemical labelling of the hea...
Source: Acta Histochemica - December 1, 2023 Category: Biochemistry Authors: Gabriella Meier B ürgisser Dorothea M Heuberger Julia Rieber Iris Miescher Pietro Giovanoli Maurizio Calcagni Johanna Buschmann Source Type: research
Catalpol antagonizes LPS-mediated inflammation and promotes osteoblast differentiation through the miR-124-3p/DNMT3b/TRAF6 axis
CONCLUSION: Catalpol antagonizes LPS-mediated inflammation and suppressive osteoblast differentiation via controlling the miR-124-3p/DNMT3b/TRAF6 axis.PMID:38039796 | DOI:10.1016/j.acthis.2023.152118 (Source: Acta Histochemica)
Source: Acta Histochemica - December 1, 2023 Category: Biochemistry Authors: Pan Zhang Qun Feng Wenxiao Chen Xizhuang Bai Source Type: research
BrdU does not induce hepatocellular damage in experimental Wistar rats
In this study, we evaluate the systemic and hepatocellular impact of BrdU in male adult Wistar rats in 30 %-partial hepatectomy (PHx) model. The rats received BrdU 50 mg/Kg by intraperitoneal injection at 0.5, 1, 2, 3, 6, 9 and 16 days after 30 %-PH. The rats were distributed into four groups as follows, control, sham, PHx/BrdU(-) and PHx/BrdU(+). On day 16, we evaluated hepatocellular nuclei and analyzed histopathological features by haematoxylin-eosin stain and apoptotic profile was qualified by caspase-3 presence. The systemic effect was evaluated by liver markers such as alanine transferase (ALT), aspartate aminotransf...
Source: Acta Histochemica - November 28, 2023 Category: Biochemistry Authors: Abril Alondra Barrientos-Bonilla Paola Belem Pensado-Guevara Abraham Puga-Olgu ín Rasajna Nadella Aurora Del Carmen S ánchez-García Laura Mireya Zavala-Flores Arnulfo Villanueva-Olivo Iliana Tamara Cibri án-Llanderal Mar ía de Jesús Rovirosa-Hernán Source Type: research
BrdU does not induce hepatocellular damage in experimental Wistar rats
In this study, we evaluate the systemic and hepatocellular impact of BrdU in male adult Wistar rats in 30 %-partial hepatectomy (PHx) model. The rats received BrdU 50 mg/Kg by intraperitoneal injection at 0.5, 1, 2, 3, 6, 9 and 16 days after 30 %-PH. The rats were distributed into four groups as follows, control, sham, PHx/BrdU(-) and PHx/BrdU(+). On day 16, we evaluated hepatocellular nuclei and analyzed histopathological features by haematoxylin-eosin stain and apoptotic profile was qualified by caspase-3 presence. The systemic effect was evaluated by liver markers such as alanine transferase (ALT), aspartate aminotransf...
Source: Acta Histochemica - November 28, 2023 Category: Biochemistry Authors: Abril Alondra Barrientos-Bonilla Paola Belem Pensado-Guevara Abraham Puga-Olgu ín Rasajna Nadella Aurora Del Carmen S ánchez-García Laura Mireya Zavala-Flores Arnulfo Villanueva-Olivo Iliana Tamara Cibri án-Llanderal Mar ía de Jesús Rovirosa-Hernán Source Type: research
BrdU does not induce hepatocellular damage in experimental Wistar rats
In this study, we evaluate the systemic and hepatocellular impact of BrdU in male adult Wistar rats in 30 %-partial hepatectomy (PHx) model. The rats received BrdU 50 mg/Kg by intraperitoneal injection at 0.5, 1, 2, 3, 6, 9 and 16 days after 30 %-PH. The rats were distributed into four groups as follows, control, sham, PHx/BrdU(-) and PHx/BrdU(+). On day 16, we evaluated hepatocellular nuclei and analyzed histopathological features by haematoxylin-eosin stain and apoptotic profile was qualified by caspase-3 presence. The systemic effect was evaluated by liver markers such as alanine transferase (ALT), aspartate aminotransf...
Source: Acta Histochemica - November 28, 2023 Category: Biochemistry Authors: Abril Alondra Barrientos-Bonilla Paola Belem Pensado-Guevara Abraham Puga-Olgu ín Rasajna Nadella Aurora Del Carmen S ánchez-García Laura Mireya Zavala-Flores Arnulfo Villanueva-Olivo Iliana Tamara Cibri án-Llanderal Mar ía de Jesús Rovirosa-Hernán Source Type: research
Histological and cytochemical analysis of the brain under conditions of hypobaric hypoxia-induced oxygen deficiency in albino rats
Acta Histochem. 2023 Nov 17;125(8):152114. doi: 10.1016/j.acthis.2023.152114. Online ahead of print.ABSTRACTHigh altitude sickness is a life-threatening disease that occurs among acclimatized individuals working or living at a high altitude accompanied by hypobaric hypoxia exposure. The prolonged influence of hypobaric hypoxia on the brain may trigger neuronal damage and cell death due to an oxygen deficiency. The purpose of the current study was to investigate the histomorphological changes in the hippocampus, cerebral cortex, cerebellar cortex, and striatum of the rat's brain following chronic hypobaric hypoxia. Fourteen...
Source: Acta Histochemica - November 19, 2023 Category: Biochemistry Authors: Ruzanna Shushanyan Anna Grigoryan Tamara Abgaryan Anna Karapetyan Source Type: research
Histological and cytochemical analysis of the brain under conditions of hypobaric hypoxia-induced oxygen deficiency in albino rats
Acta Histochem. 2023 Nov 17;125(8):152114. doi: 10.1016/j.acthis.2023.152114. Online ahead of print.ABSTRACTHigh altitude sickness is a life-threatening disease that occurs among acclimatized individuals working or living at a high altitude accompanied by hypobaric hypoxia exposure. The prolonged influence of hypobaric hypoxia on the brain may trigger neuronal damage and cell death due to an oxygen deficiency. The purpose of the current study was to investigate the histomorphological changes in the hippocampus, cerebral cortex, cerebellar cortex, and striatum of the rat's brain following chronic hypobaric hypoxia. Fourteen...
Source: Acta Histochemica - November 19, 2023 Category: Biochemistry Authors: Ruzanna Shushanyan Anna Grigoryan Tamara Abgaryan Anna Karapetyan Source Type: research
Histological and cytochemical analysis of the brain under conditions of hypobaric hypoxia-induced oxygen deficiency in albino rats
Acta Histochem. 2023 Nov 17;125(8):152114. doi: 10.1016/j.acthis.2023.152114. Online ahead of print.ABSTRACTHigh altitude sickness is a life-threatening disease that occurs among acclimatized individuals working or living at a high altitude accompanied by hypobaric hypoxia exposure. The prolonged influence of hypobaric hypoxia on the brain may trigger neuronal damage and cell death due to an oxygen deficiency. The purpose of the current study was to investigate the histomorphological changes in the hippocampus, cerebral cortex, cerebellar cortex, and striatum of the rat's brain following chronic hypobaric hypoxia. Fourteen...
Source: Acta Histochemica - November 19, 2023 Category: Biochemistry Authors: Ruzanna Shushanyan Anna Grigoryan Tamara Abgaryan Anna Karapetyan Source Type: research
Histological and cytochemical analysis of the brain under conditions of hypobaric hypoxia-induced oxygen deficiency in albino rats
Acta Histochem. 2023 Nov 17;125(8):152114. doi: 10.1016/j.acthis.2023.152114. Online ahead of print.ABSTRACTHigh altitude sickness is a life-threatening disease that occurs among acclimatized individuals working or living at a high altitude accompanied by hypobaric hypoxia exposure. The prolonged influence of hypobaric hypoxia on the brain may trigger neuronal damage and cell death due to an oxygen deficiency. The purpose of the current study was to investigate the histomorphological changes in the hippocampus, cerebral cortex, cerebellar cortex, and striatum of the rat's brain following chronic hypobaric hypoxia. Fourteen...
Source: Acta Histochemica - November 19, 2023 Category: Biochemistry Authors: Ruzanna Shushanyan Anna Grigoryan Tamara Abgaryan Anna Karapetyan Source Type: research
Histological and cytochemical analysis of the brain under conditions of hypobaric hypoxia-induced oxygen deficiency in albino rats
Acta Histochem. 2023 Nov 17;125(8):152114. doi: 10.1016/j.acthis.2023.152114. Online ahead of print.ABSTRACTHigh altitude sickness is a life-threatening disease that occurs among acclimatized individuals working or living at a high altitude accompanied by hypobaric hypoxia exposure. The prolonged influence of hypobaric hypoxia on the brain may trigger neuronal damage and cell death due to an oxygen deficiency. The purpose of the current study was to investigate the histomorphological changes in the hippocampus, cerebral cortex, cerebellar cortex, and striatum of the rat's brain following chronic hypobaric hypoxia. Fourteen...
Source: Acta Histochemica - November 19, 2023 Category: Biochemistry Authors: Ruzanna Shushanyan Anna Grigoryan Tamara Abgaryan Anna Karapetyan Source Type: research
Histological and cytochemical analysis of the brain under conditions of hypobaric hypoxia-induced oxygen deficiency in albino rats
Acta Histochem. 2023 Nov 17;125(8):152114. doi: 10.1016/j.acthis.2023.152114. Online ahead of print.ABSTRACTHigh altitude sickness is a life-threatening disease that occurs among acclimatized individuals working or living at a high altitude accompanied by hypobaric hypoxia exposure. The prolonged influence of hypobaric hypoxia on the brain may trigger neuronal damage and cell death due to an oxygen deficiency. The purpose of the current study was to investigate the histomorphological changes in the hippocampus, cerebral cortex, cerebellar cortex, and striatum of the rat's brain following chronic hypobaric hypoxia. Fourteen...
Source: Acta Histochemica - November 19, 2023 Category: Biochemistry Authors: Ruzanna Shushanyan Anna Grigoryan Tamara Abgaryan Anna Karapetyan Source Type: research
Association between neuropeptides and mucins in Crohn's disease mucous cells
This study aims to define the link between neuropeptides and mucins in mucous cells and their involvement in the inflammation process. Our results showed in mucous cells of Crohn's disease (CD) patients a high expression of MUC4 and a decrease in the expression of vesicular acetylcholine transporter (VAChT) demonstrating the presence of an inflammatory state.PMID:37979446 | DOI:10.1016/j.acthis.2023.152115 (Source: Acta Histochemica)
Source: Acta Histochemica - November 18, 2023 Category: Biochemistry Authors: Anthea Miller Giuseppina Cutroneo Giorgia Pia Lombardo Roberta D'Angelo Socrate Pallio Alba Migliorato Angelo Fumia Angelo Favaloro Eugenia Rita Lauriano Simona Pergolizzi Source Type: research
Association between neuropeptides and mucins in Crohn's disease mucous cells
This study aims to define the link between neuropeptides and mucins in mucous cells and their involvement in the inflammation process. Our results showed in mucous cells of Crohn's disease (CD) patients a high expression of MUC4 and a decrease in the expression of vesicular acetylcholine transporter (VAChT) demonstrating the presence of an inflammatory state.PMID:37979446 | DOI:10.1016/j.acthis.2023.152115 (Source: Acta Histochemica)
Source: Acta Histochemica - November 18, 2023 Category: Biochemistry Authors: Anthea Miller Giuseppina Cutroneo Giorgia Pia Lombardo Roberta D'Angelo Socrate Pallio Alba Migliorato Angelo Fumia Angelo Favaloro Eugenia Rita Lauriano Simona Pergolizzi Source Type: research
Beneficial Effect of Erythropoietin on Ameliorating Propionic Acid-Induced Autistic-Like Features in Young Rats
This study investigated the possible beneficial effects of erythropoietin (EPO) on experimental autistic-like behaviors induced by propionic acid (PPA). Twenty-four rats were distributed into three groups: (i) control; (ii) PPA_Gp: daily injected subcutaneously with PPA for five consecutive days; PPA+EPO-Gp: injected with PPA, then received intraperitoneal injection of EPO once daily for two weeks. Behavioral changes in the rats were assessed. Specimens from the cerebellar hemispheres were subjected to histological and ultrastructure examination, immunohistochemistry for glial fibrillary acidic protein (GFAP) and calbindin...
Source: Acta Histochemica - November 16, 2023 Category: Biochemistry Authors: Sara A Hosny Alshaymaa M Abdelmenem Taha Azouz Samaa S Kamar Asmaa M ShamsEldeen Asmaa A El-Shafei Source Type: research
