Investigation of the differentiation potential of pericyte cells as an alternative source of mesenchymal stem cells
In this study, therefore, we conducted molecular level examinations to determine whether pericytes, specialized cell communities situated near blood vessels, could serve as a substitute for human bone marrow-derived mesenchymal stem cells (hBM-MSCs). In this context, the potential application of pericytes surrounds the vessels when MSCs are insufficient for functional purposes.METHODS: The pericytes utilized in this investigation were derived from the placenta and characterized at the third passage. Similarly, the hBM-MSCs were also characterized at the third passage. The pluripotent properties of the two cell types were a...
Source: Acta Histochemica - March 3, 2024 Category: Biochemistry Authors: Selen Polat Yusufhan Yazir G ökhan Duruksu Kamil Can Kili ç Serap Mert G ülçin Gacar B üşra Öncel Duman Zehra Seda Halbuto ğullari Source Type: research
Investigation of the differentiation potential of pericyte cells as an alternative source of mesenchymal stem cells
In this study, therefore, we conducted molecular level examinations to determine whether pericytes, specialized cell communities situated near blood vessels, could serve as a substitute for human bone marrow-derived mesenchymal stem cells (hBM-MSCs). In this context, the potential application of pericytes surrounds the vessels when MSCs are insufficient for functional purposes.METHODS: The pericytes utilized in this investigation were derived from the placenta and characterized at the third passage. Similarly, the hBM-MSCs were also characterized at the third passage. The pluripotent properties of the two cell types were a...
Source: Acta Histochemica - March 3, 2024 Category: Biochemistry Authors: Selen Polat Yusufhan Yazir G ökhan Duruksu Kamil Can Kili ç Serap Mert G ülçin Gacar B üşra Öncel Duman Zehra Seda Halbuto ğullari Source Type: research
Investigation of the differentiation potential of pericyte cells as an alternative source of mesenchymal stem cells
In this study, therefore, we conducted molecular level examinations to determine whether pericytes, specialized cell communities situated near blood vessels, could serve as a substitute for human bone marrow-derived mesenchymal stem cells (hBM-MSCs). In this context, the potential application of pericytes surrounds the vessels when MSCs are insufficient for functional purposes.METHODS: The pericytes utilized in this investigation were derived from the placenta and characterized at the third passage. Similarly, the hBM-MSCs were also characterized at the third passage. The pluripotent properties of the two cell types were a...
Source: Acta Histochemica - March 3, 2024 Category: Biochemistry Authors: Selen Polat Yusufhan Yazir G ökhan Duruksu Kamil Can Kili ç Serap Mert G ülçin Gacar B üşra Öncel Duman Zehra Seda Halbuto ğullari Source Type: research
Investigation of the differentiation potential of pericyte cells as an alternative source of mesenchymal stem cells
In this study, therefore, we conducted molecular level examinations to determine whether pericytes, specialized cell communities situated near blood vessels, could serve as a substitute for human bone marrow-derived mesenchymal stem cells (hBM-MSCs). In this context, the potential application of pericytes surrounds the vessels when MSCs are insufficient for functional purposes.METHODS: The pericytes utilized in this investigation were derived from the placenta and characterized at the third passage. Similarly, the hBM-MSCs were also characterized at the third passage. The pluripotent properties of the two cell types were a...
Source: Acta Histochemica - March 3, 2024 Category: Biochemistry Authors: Selen Polat Yusufhan Yazir G ökhan Duruksu Kamil Can Kili ç Serap Mert G ülçin Gacar B üşra Öncel Duman Zehra Seda Halbuto ğullari Source Type: research
Cancer-induced morphological changes in enteric glial cells in the jejunum of Walker-256 tumor-bearing rats
Acta Histochem. 2024 Feb 28;126(3):152146. doi: 10.1016/j.acthis.2024.152146. Online ahead of print.ABSTRACTCancer-induced cachexia is associated with systemic inflammation and gastrointestinal dysfunction. How changes to cells of the enteric nervous system contribute to gut dysfunction in tumor development and cancer cachexia is unknown. Here, we tested the hypothesis that changes to enteric glia, a type of peripheral glia that surround enteric neurons and regulate gut homeostasis, are associated with tumor development and that supplementing with the antioxidant L-glutathione is protective against the changes induced. Imm...
Source: Acta Histochemica - February 29, 2024 Category: Biochemistry Authors: Fabiana Galv ão da Motta Lima Maysa Pacheco Alvarez da Silva Sabrina Silva Sestak Fl ávia Alessandra Guarnier Ana Paula de Oliveira Jo ão Victor Kuller Brian David Gulbransen Juliana Vanessa Colombo Martins Perles Jacqueline Nelisis Zanoni Source Type: research
Cancer-induced morphological changes in enteric glial cells in the jejunum of Walker-256 tumor-bearing rats
Acta Histochem. 2024 Feb 28;126(3):152146. doi: 10.1016/j.acthis.2024.152146. Online ahead of print.ABSTRACTCancer-induced cachexia is associated with systemic inflammation and gastrointestinal dysfunction. How changes to cells of the enteric nervous system contribute to gut dysfunction in tumor development and cancer cachexia is unknown. Here, we tested the hypothesis that changes to enteric glia, a type of peripheral glia that surround enteric neurons and regulate gut homeostasis, are associated with tumor development and that supplementing with the antioxidant L-glutathione is protective against the changes induced. Imm...
Source: Acta Histochemica - February 29, 2024 Category: Biochemistry Authors: Fabiana Galv ão da Motta Lima Maysa Pacheco Alvarez da Silva Sabrina Silva Sestak Fl ávia Alessandra Guarnier Ana Paula de Oliveira Jo ão Victor Kuller Brian David Gulbransen Juliana Vanessa Colombo Martins Perles Jacqueline Nelisis Zanoni Source Type: research
Cancer-induced morphological changes in enteric glial cells in the jejunum of Walker-256 tumor-bearing rats
Acta Histochem. 2024 Feb 28;126(3):152146. doi: 10.1016/j.acthis.2024.152146. Online ahead of print.ABSTRACTCancer-induced cachexia is associated with systemic inflammation and gastrointestinal dysfunction. How changes to cells of the enteric nervous system contribute to gut dysfunction in tumor development and cancer cachexia is unknown. Here, we tested the hypothesis that changes to enteric glia, a type of peripheral glia that surround enteric neurons and regulate gut homeostasis, are associated with tumor development and that supplementing with the antioxidant L-glutathione is protective against the changes induced. Imm...
Source: Acta Histochemica - February 29, 2024 Category: Biochemistry Authors: Fabiana Galv ão da Motta Lima Maysa Pacheco Alvarez da Silva Sabrina Silva Sestak Fl ávia Alessandra Guarnier Ana Paula de Oliveira Jo ão Victor Kuller Brian David Gulbransen Juliana Vanessa Colombo Martins Perles Jacqueline Nelisis Zanoni Source Type: research
Immunolocalization patterns of histone-deacetylases in salivary glands of mice during postnatal development
CONCLUSIONS: This study has provided an important reference for understanding the spatiotemporal-specific expression of HDACs in the salivary gland. These results offer new clues for the experimenters and hold promise for developing innovative therapeutic strategies for salivary gland-related diseases.PMID:38382218 | DOI:10.1016/j.acthis.2024.152144 (Source: Acta Histochemica)
Source: Acta Histochemica - February 21, 2024 Category: Biochemistry Authors: Chubo Yang Xuejing Song Jiaqi Kong Huishu Li Yuanbo Zhan Source Type: research
Sialylation status and its relationship with morphofunctional changes in human adult testis during sexually mature life and aging: A narrative review
Acta Histochem. 2024 Feb 20;126(2):152143. doi: 10.1016/j.acthis.2024.152143. Online ahead of print.ABSTRACTSialic acids (Sias) are a family of electronegatively charged nine-carbon monosaccharides containing a carboxylic acid, mostly found as terminal residues in glycans of glycoproteins and glycolipids. They are bound to galactose or N-acetylgalactosamine via α2,3 or α2,6 linkage, or to other Sias especially via α2,8 linkage, which results in monomeric, oligomeric, and polymeric forms. Sias play determinant roles in a multitude of biological processes in human tissues from development to adult life until aging. In thi...
Source: Acta Histochemica - February 21, 2024 Category: Biochemistry Authors: Mirko Manetti Mirca Marini Angelica Perna Alessia Tani Eleonora Sgambati Source Type: research
Immunolocalization patterns of histone-deacetylases in salivary glands of mice during postnatal development
CONCLUSIONS: This study has provided an important reference for understanding the spatiotemporal-specific expression of HDACs in the salivary gland. These results offer new clues for the experimenters and hold promise for developing innovative therapeutic strategies for salivary gland-related diseases.PMID:38382218 | DOI:10.1016/j.acthis.2024.152144 (Source: Acta Histochemica)
Source: Acta Histochemica - February 21, 2024 Category: Biochemistry Authors: Chubo Yang Xuejing Song Jiaqi Kong Huishu Li Yuanbo Zhan Source Type: research
Sialylation status and its relationship with morphofunctional changes in human adult testis during sexually mature life and aging: A narrative review
Acta Histochem. 2024 Feb 20;126(2):152143. doi: 10.1016/j.acthis.2024.152143. Online ahead of print.ABSTRACTSialic acids (Sias) are a family of electronegatively charged nine-carbon monosaccharides containing a carboxylic acid, mostly found as terminal residues in glycans of glycoproteins and glycolipids. They are bound to galactose or N-acetylgalactosamine via α2,3 or α2,6 linkage, or to other Sias especially via α2,8 linkage, which results in monomeric, oligomeric, and polymeric forms. Sias play determinant roles in a multitude of biological processes in human tissues from development to adult life until aging. In thi...
Source: Acta Histochemica - February 21, 2024 Category: Biochemistry Authors: Mirko Manetti Mirca Marini Angelica Perna Alessia Tani Eleonora Sgambati Source Type: research
Immunolocalization patterns of histone-deacetylases in salivary glands of mice during postnatal development
CONCLUSIONS: This study has provided an important reference for understanding the spatiotemporal-specific expression of HDACs in the salivary gland. These results offer new clues for the experimenters and hold promise for developing innovative therapeutic strategies for salivary gland-related diseases.PMID:38382218 | DOI:10.1016/j.acthis.2024.152144 (Source: Acta Histochemica)
Source: Acta Histochemica - February 21, 2024 Category: Biochemistry Authors: Chubo Yang Xuejing Song Jiaqi Kong Huishu Li Yuanbo Zhan Source Type: research
Sialylation status and its relationship with morphofunctional changes in human adult testis during sexually mature life and aging: A narrative review
Acta Histochem. 2024 Feb 20;126(2):152143. doi: 10.1016/j.acthis.2024.152143. Online ahead of print.ABSTRACTSialic acids (Sias) are a family of electronegatively charged nine-carbon monosaccharides containing a carboxylic acid, mostly found as terminal residues in glycans of glycoproteins and glycolipids. They are bound to galactose or N-acetylgalactosamine via α2,3 or α2,6 linkage, or to other Sias especially via α2,8 linkage, which results in monomeric, oligomeric, and polymeric forms. Sias play determinant roles in a multitude of biological processes in human tissues from development to adult life until aging. In thi...
Source: Acta Histochemica - February 21, 2024 Category: Biochemistry Authors: Mirko Manetti Mirca Marini Angelica Perna Alessia Tani Eleonora Sgambati Source Type: research
Immunolocalization patterns of histone-deacetylases in salivary glands of mice during postnatal development
CONCLUSIONS: This study has provided an important reference for understanding the spatiotemporal-specific expression of HDACs in the salivary gland. These results offer new clues for the experimenters and hold promise for developing innovative therapeutic strategies for salivary gland-related diseases.PMID:38382218 | DOI:10.1016/j.acthis.2024.152144 (Source: Acta Histochemica)
Source: Acta Histochemica - February 21, 2024 Category: Biochemistry Authors: Chubo Yang Xuejing Song Jiaqi Kong Huishu Li Yuanbo Zhan Source Type: research
Sialylation status and its relationship with morphofunctional changes in human adult testis during sexually mature life and aging: A narrative review
Acta Histochem. 2024 Feb 20;126(2):152143. doi: 10.1016/j.acthis.2024.152143. Online ahead of print.ABSTRACTSialic acids (Sias) are a family of electronegatively charged nine-carbon monosaccharides containing a carboxylic acid, mostly found as terminal residues in glycans of glycoproteins and glycolipids. They are bound to galactose or N-acetylgalactosamine via α2,3 or α2,6 linkage, or to other Sias especially via α2,8 linkage, which results in monomeric, oligomeric, and polymeric forms. Sias play determinant roles in a multitude of biological processes in human tissues from development to adult life until aging. In thi...
Source: Acta Histochemica - February 21, 2024 Category: Biochemistry Authors: Mirko Manetti Mirca Marini Angelica Perna Alessia Tani Eleonora Sgambati Source Type: research
