Immunohistochemical and ultrastructural identification of telocytes in the lamina propria of human vaginal mucosa
Acta Histochem. 2023 Sep 25;125(7):152094. doi: 10.1016/j.acthis.2023.152094. Online ahead of print.ABSTRACTSince their relatively recent discovery, telocytes (TCs) have been described as peculiar cells strategically positioned in the stromal tissue component of multiple organ systems of the mammalian body including female reproductive organs (i.e., ovary, uterine tube, and uterus). Nevertheless, current knowledge of TCs in the vagina is very limited. The present study was therefore undertaken to investigate the existence and characteristics of TCs in the stromal tissue of human vaginal mucosa by means of immunohistochemis...
Source: Acta Histochemica - September 27, 2023 Category: Biochemistry Authors: Irene Rosa Patrizia Nardini Bianca Saveria Fioretto Daniele Guasti Eloisa Romano Eleonora Sgambati Mirca Marini Mirko Manetti Source Type: research

Topiramate promotes osteogenic differentiation through AMPK-dependent phosphorylation of Smad1/5/9
Acta Histochem. 2023 Sep 25;125(7):152095. doi: 10.1016/j.acthis.2023.152095. Online ahead of print.ABSTRACTTopiramate [2,3:4,5-bis-o-(1-methylethylidene) β-D-fructo-pyranose sulfamate; TPM] is one of the most used new-generation antiepileptic drugs. It has been reported to regulate the differentiation of human bone cells. However, the molecular mechanism of TPM in osteoblast differentiation is not fully elucidated. In the present study, we examined the effect of TPM on osteogenic differentiation of C3H10T1/2, MC3T3-E1, primary mouse calvarial cells, and primary bone marrow stem cells (BMSCs). Primary cells were isolated ...
Source: Acta Histochemica - September 27, 2023 Category: Biochemistry Authors: Kyeong-Min Kim Hyo-Eun Son Young-Ju Lim Won-Gu Jang Source Type: research

Epithelial polarity-driven membrane separation but not cavitation regulates lumen formation of rat eccrine sweat glands
CONCLUSIONS: Epithelial polarity-driven membrane separation but not cavitation regulates lumen formation of SD rat ESGs. NKA-regulated fluid accumulation drives lumen expansion.PMID:37757514 | DOI:10.1016/j.acthis.2023.152093 (Source: Acta Histochemica)
Source: Acta Histochemica - September 27, 2023 Category: Biochemistry Authors: Zixiu Chen Junhong Zhao Cangyu Wang Xiang Liu Zihua Chen Jianda Zhou Lei Zhang Cuiping Zhang Haihong Li Source Type: research

Immunohistochemical and ultrastructural identification of telocytes in the lamina propria of human vaginal mucosa
Acta Histochem. 2023 Sep 25;125(7):152094. doi: 10.1016/j.acthis.2023.152094. Online ahead of print.ABSTRACTSince their relatively recent discovery, telocytes (TCs) have been described as peculiar cells strategically positioned in the stromal tissue component of multiple organ systems of the mammalian body including female reproductive organs (i.e., ovary, uterine tube, and uterus). Nevertheless, current knowledge of TCs in the vagina is very limited. The present study was therefore undertaken to investigate the existence and characteristics of TCs in the stromal tissue of human vaginal mucosa by means of immunohistochemis...
Source: Acta Histochemica - September 27, 2023 Category: Biochemistry Authors: Irene Rosa Patrizia Nardini Bianca Saveria Fioretto Daniele Guasti Eloisa Romano Eleonora Sgambati Mirca Marini Mirko Manetti Source Type: research

Topiramate promotes osteogenic differentiation through AMPK-dependent phosphorylation of Smad1/5/9
Acta Histochem. 2023 Sep 25;125(7):152095. doi: 10.1016/j.acthis.2023.152095. Online ahead of print.ABSTRACTTopiramate [2,3:4,5-bis-o-(1-methylethylidene) β-D-fructo-pyranose sulfamate; TPM] is one of the most used new-generation antiepileptic drugs. It has been reported to regulate the differentiation of human bone cells. However, the molecular mechanism of TPM in osteoblast differentiation is not fully elucidated. In the present study, we examined the effect of TPM on osteogenic differentiation of C3H10T1/2, MC3T3-E1, primary mouse calvarial cells, and primary bone marrow stem cells (BMSCs). Primary cells were isolated ...
Source: Acta Histochemica - September 27, 2023 Category: Biochemistry Authors: Kyeong-Min Kim Hyo-Eun Son Young-Ju Lim Won-Gu Jang Source Type: research

Epithelial polarity-driven membrane separation but not cavitation regulates lumen formation of rat eccrine sweat glands
CONCLUSIONS: Epithelial polarity-driven membrane separation but not cavitation regulates lumen formation of SD rat ESGs. NKA-regulated fluid accumulation drives lumen expansion.PMID:37757514 | DOI:10.1016/j.acthis.2023.152093 (Source: Acta Histochemica)
Source: Acta Histochemica - September 27, 2023 Category: Biochemistry Authors: Zixiu Chen Junhong Zhao Cangyu Wang Xiang Liu Zihua Chen Jianda Zhou Lei Zhang Cuiping Zhang Haihong Li Source Type: research

Immunohistochemical and ultrastructural identification of telocytes in the lamina propria of human vaginal mucosa
Acta Histochem. 2023 Sep 25;125(7):152094. doi: 10.1016/j.acthis.2023.152094. Online ahead of print.ABSTRACTSince their relatively recent discovery, telocytes (TCs) have been described as peculiar cells strategically positioned in the stromal tissue component of multiple organ systems of the mammalian body including female reproductive organs (i.e., ovary, uterine tube, and uterus). Nevertheless, current knowledge of TCs in the vagina is very limited. The present study was therefore undertaken to investigate the existence and characteristics of TCs in the stromal tissue of human vaginal mucosa by means of immunohistochemis...
Source: Acta Histochemica - September 27, 2023 Category: Biochemistry Authors: Irene Rosa Patrizia Nardini Bianca Saveria Fioretto Daniele Guasti Eloisa Romano Eleonora Sgambati Mirca Marini Mirko Manetti Source Type: research

Topiramate promotes osteogenic differentiation through AMPK-dependent phosphorylation of Smad1/5/9
Acta Histochem. 2023 Sep 25;125(7):152095. doi: 10.1016/j.acthis.2023.152095. Online ahead of print.ABSTRACTTopiramate [2,3:4,5-bis-o-(1-methylethylidene) β-D-fructo-pyranose sulfamate; TPM] is one of the most used new-generation antiepileptic drugs. It has been reported to regulate the differentiation of human bone cells. However, the molecular mechanism of TPM in osteoblast differentiation is not fully elucidated. In the present study, we examined the effect of TPM on osteogenic differentiation of C3H10T1/2, MC3T3-E1, primary mouse calvarial cells, and primary bone marrow stem cells (BMSCs). Primary cells were isolated ...
Source: Acta Histochemica - September 27, 2023 Category: Biochemistry Authors: Kyeong-Min Kim Hyo-Eun Son Young-Ju Lim Won-Gu Jang Source Type: research

Epithelial polarity-driven membrane separation but not cavitation regulates lumen formation of rat eccrine sweat glands
CONCLUSIONS: Epithelial polarity-driven membrane separation but not cavitation regulates lumen formation of SD rat ESGs. NKA-regulated fluid accumulation drives lumen expansion.PMID:37757514 | DOI:10.1016/j.acthis.2023.152093 (Source: Acta Histochemica)
Source: Acta Histochemica - September 27, 2023 Category: Biochemistry Authors: Zixiu Chen Junhong Zhao Cangyu Wang Xiang Liu Zihua Chen Jianda Zhou Lei Zhang Cuiping Zhang Haihong Li Source Type: research

Immunohistochemical and ultrastructural identification of telocytes in the lamina propria of human vaginal mucosa
Acta Histochem. 2023 Sep 25;125(7):152094. doi: 10.1016/j.acthis.2023.152094. Online ahead of print.ABSTRACTSince their relatively recent discovery, telocytes (TCs) have been described as peculiar cells strategically positioned in the stromal tissue component of multiple organ systems of the mammalian body including female reproductive organs (i.e., ovary, uterine tube, and uterus). Nevertheless, current knowledge of TCs in the vagina is very limited. The present study was therefore undertaken to investigate the existence and characteristics of TCs in the stromal tissue of human vaginal mucosa by means of immunohistochemis...
Source: Acta Histochemica - September 27, 2023 Category: Biochemistry Authors: Irene Rosa Patrizia Nardini Bianca Saveria Fioretto Daniele Guasti Eloisa Romano Eleonora Sgambati Mirca Marini Mirko Manetti Source Type: research

Topiramate promotes osteogenic differentiation through AMPK-dependent phosphorylation of Smad1/5/9
Acta Histochem. 2023 Sep 25;125(7):152095. doi: 10.1016/j.acthis.2023.152095. Online ahead of print.ABSTRACTTopiramate [2,3:4,5-bis-o-(1-methylethylidene) β-D-fructo-pyranose sulfamate; TPM] is one of the most used new-generation antiepileptic drugs. It has been reported to regulate the differentiation of human bone cells. However, the molecular mechanism of TPM in osteoblast differentiation is not fully elucidated. In the present study, we examined the effect of TPM on osteogenic differentiation of C3H10T1/2, MC3T3-E1, primary mouse calvarial cells, and primary bone marrow stem cells (BMSCs). Primary cells were isolated ...
Source: Acta Histochemica - September 27, 2023 Category: Biochemistry Authors: Kyeong-Min Kim Hyo-Eun Son Young-Ju Lim Won-Gu Jang Source Type: research

Epithelial polarity-driven membrane separation but not cavitation regulates lumen formation of rat eccrine sweat glands
CONCLUSIONS: Epithelial polarity-driven membrane separation but not cavitation regulates lumen formation of SD rat ESGs. NKA-regulated fluid accumulation drives lumen expansion.PMID:37757514 | DOI:10.1016/j.acthis.2023.152093 (Source: Acta Histochemica)
Source: Acta Histochemica - September 27, 2023 Category: Biochemistry Authors: Zixiu Chen Junhong Zhao Cangyu Wang Xiang Liu Zihua Chen Jianda Zhou Lei Zhang Cuiping Zhang Haihong Li Source Type: research

Immunohistochemical and ultrastructural identification of telocytes in the lamina propria of human vaginal mucosa
Acta Histochem. 2023 Sep 25;125(7):152094. doi: 10.1016/j.acthis.2023.152094. Online ahead of print.ABSTRACTSince their relatively recent discovery, telocytes (TCs) have been described as peculiar cells strategically positioned in the stromal tissue component of multiple organ systems of the mammalian body including female reproductive organs (i.e., ovary, uterine tube, and uterus). Nevertheless, current knowledge of TCs in the vagina is very limited. The present study was therefore undertaken to investigate the existence and characteristics of TCs in the stromal tissue of human vaginal mucosa by means of immunohistochemis...
Source: Acta Histochemica - September 27, 2023 Category: Biochemistry Authors: Irene Rosa Patrizia Nardini Bianca Saveria Fioretto Daniele Guasti Eloisa Romano Eleonora Sgambati Mirca Marini Mirko Manetti Source Type: research

Topiramate promotes osteogenic differentiation through AMPK-dependent phosphorylation of Smad1/5/9
Acta Histochem. 2023 Sep 25;125(7):152095. doi: 10.1016/j.acthis.2023.152095. Online ahead of print.ABSTRACTTopiramate [2,3:4,5-bis-o-(1-methylethylidene) β-D-fructo-pyranose sulfamate; TPM] is one of the most used new-generation antiepileptic drugs. It has been reported to regulate the differentiation of human bone cells. However, the molecular mechanism of TPM in osteoblast differentiation is not fully elucidated. In the present study, we examined the effect of TPM on osteogenic differentiation of C3H10T1/2, MC3T3-E1, primary mouse calvarial cells, and primary bone marrow stem cells (BMSCs). Primary cells were isolated ...
Source: Acta Histochemica - September 27, 2023 Category: Biochemistry Authors: Kyeong-Min Kim Hyo-Eun Son Young-Ju Lim Won-Gu Jang Source Type: research

Tissue and subcellular localization of CycD2 and KRPs are dissimilarly distributed by glucose and sucrose during early maize germination
Acta Histochem. 2023 Sep 15;125(7):152092. doi: 10.1016/j.acthis.2023.152092. Online ahead of print.ABSTRACTIn maize, immunoprecipitation assays have shown that CycD2;2 interacts with KRPs. However, evidence on CycD2;2 or KRPs localization and their possible interaction in specific tissues is lacking and its physiological consequence is still unknown. This work explores the spatiotemporal presence of CyclinD2s and KRPs, cell cycle regulators, during maize seed germination (18 and 36 h) after soaking on glucose or sucrose (120 mM). CyclinD2s are positive actors driving proliferation; KRPs are inhibitors of the main kinase c...
Source: Acta Histochemica - September 17, 2023 Category: Biochemistry Authors: Diana I Romero-S ánchez Sonia V ázquez-Santana Rafael A Alonso-Alvarez Jorge M V ázquez-Ramos Aurora Lara-N úñez Source Type: research