The medicare annual wellness visit: an opportunity to improve geriatric knowledge among internal medicine resident physicians
. (Source: Gerentology and Geriatrics Educations)
Source: Gerentology and Geriatrics Educations - May 26, 2023 Category: Geriatrics Authors: David HurwitzHeather AgeeMariah RobertsonJessica L. Colburna Division of Geriatric Medicine and Gerontology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USAb Division of General Internal Medicine, Johns Hopkins University School of M Source Type: research
Managing Antiseizure Medications in Pregnancy: Is Earlier and More Frequent Monitoring Better?
This study demonstrates that frequency and timing of ASM level monitoring may not affect overall seizure outcomes during pregnancy in those on lamotrigine or levetiracetam. Furthermore, one can consider preemptive dose adjustments or a laboratory-based/clinical-based approach in managing lamotrigine as both seem safe and feasible. However, in those with drug-resistant epilepsy before pregnancy, earlier and closer monitoring is warranted given the risk of seizures early during pregnancy. Larger prospective studies are needed to confirm these results. (Source: Neurology Clinical Practice)
Source: Neurology Clinical Practice - May 22, 2023 Category: Neurology Authors: Freund, B., Chen, B., Kaplan, P. W., Johnson, E. L. Tags: Gender, All Epilepsy/Seizures, Antiepileptic drugs, Generalized seizures, Partial seizures Research Article Source Type: research
Effects of acute alcohol exposure and chronic alcohol use on neurite orientation dispersion and density imaging (NODDI) parameters
AbstractRationaleLittle is known about how acute and chronic alcohol exposure may alter the in vivo membrane properties of neurons.ObjectivesWe employed neurite orientation dispersion and density imaging (NODDI) to examine acute and chronic effects of alcohol exposure on neurite density.MethodsTwenty-one healthy social drinkers (CON) and thirteen nontreatment-seeking individuals with alcohol use disorder (AUD) underwent a baseline multi-shell diffusion magnetic resonance imaging (dMRI) scan. A subset (10 CON, 5 AUD) received dMRI during intravenous infusions of saline and alcohol during dMRI. NODDI parametric images includ...
Source: Psychopharmacology - May 20, 2023 Category: Psychiatry Source Type: research
World ’s largest ‘scent arena’ reveals bloody preferences of mosquitoes
In the dead of night, 200 bloodthirsty creatures make their way through a tented mesh arena the size of an ice rink. Scientists study them from afar, pumping in air scented with the aroma of human prey. They’re hoping to reveal just what triggers these deadly predators.
This isn’t the setup for an upcoming zombie movie. “It’s the world’s largest multichoice smell test for mosquitoes”—a giant experiment to figure out why the deadly insects prefer some people over others, explains study leader Conor McMeniman, a molecular biologist at Johns Hopkins University. The results, he says, could help scientists d...
Source: Science of Aging Knowledge Environment - May 19, 2023 Category: Geriatrics Source Type: research
Ketamine no better than placebo at alleviating depression, unusual trial finds
Ketamine is a powerful anesthetic and sometimes recreational drug that causes people to feel dissociated from their own bodies. Recent studies suggest the drug may help treat people with depression who have tried more conventional treatments without success. But there are major questions about what makes it work. Is it the weird dissociative experience? Some molecular effect on the brain? Or just the experience of being in a clinical trial?
In a new study that is yet to be peer reviewed, researchers attempted to find the answer in a unique way: They gave volunteers ketamine while they were under general anesthesia, t...
Source: Science of Aging Knowledge Environment - May 19, 2023 Category: Geriatrics Source Type: research
Need to keep your picnic cool? Try mushrooms instead of dry ice
“Cool as a cucumber” might be better phrased as “cool as a mushroom.” A research team has found that mushrooms and other fungi, including yeast and molds, stay cooler than their surroundings—and has also explained how they stay so chill. The contain a lot of water—just think how mushrooms shrink when cooked—and gradually release it in a fungal form of sweating that lowers their temperature, the microbiologists report this week in the
Proceedings of the National Academy of Sciences
.
“It’s kind of a neat finding,” says Christopher Still, an ecophysiologist at Oregon State University who w...
Source: Science of Aging Knowledge Environment - May 5, 2023 Category: Geriatrics Source Type: research
'It ’s still killing and it’s still changing.' Ending COVID-19 states of emergency sparks debate
The World Health Organization (WHO) today declared an end to the emergency phase of the COVID-19 pandemic, days ahead of when a similar emergency in the United States is also set to expire. Both moves are likely to usher the world into a new phase of disease monitoring with a scaling back of surveillance and available resources to fight COVID-19.
WHO’s director-general, Tedros Adhanom Ghebreyesus, said at a press conference today in Geneva that WHO’s emergency committee met yesterday and recommended ending the Public Health Emergency of International Concern (PHEIC), the highest alert level WHO can declare, that ...
Source: Science of Aging Knowledge Environment - May 5, 2023 Category: Geriatrics Source Type: research
‘It’s still killing and it’s still changing.’ Ending COVID-19 states of emergency sparks debate
The World Health Organization (WHO) today declared an end to the emergency phase of the COVID-19 pandemic, days ahead of when a similar emergency in the United States is also set to expire. Both moves are likely to usher the world into a new phase of disease monitoring with a scaling back of surveillance and available resources to fight COVID-19.
WHO’s director-general, Tedros Adhanom Ghebreyesus, said at a press conference today in Geneva that WHO’s emergency committee met yesterday and recommended ending the Public Health Emergency of International Concern (PHEIC), the highest alert level WHO can declare, that ...
Source: Science of Aging Knowledge Environment - May 5, 2023 Category: Geriatrics Source Type: research
Diagnostic concordance of telemedicine as compared to face-to-face care in primary health care clinics in rural India: a randomized crossover trial
CONCLUSIONS: Provider-to-provider telemedicine, where nurses at Health and Wellness Centres connect with remote physicians to provide care for patients they would otherwise have referred to a tertiary facility, is a feasible and safe intervention. Telemedicine is less reliable than in-person care but a safe and effective alternative where in-person care cannot be provided. We found it most effective for managing high-burden primary health conditions such as hypertension, diabetes, and remote antenatal care. The use of a digital assistant to facilitate the collection of an evidence-based medical history can result in more e...
Source: Rural Remote Health - May 2, 2023 Category: Rural Health Authors: Neha Verma Bimal Buch Radha Taralekar Soumyadipta Acharya Source Type: research
Diagnostic concordance of telemedicine as compared to face-to-face care in primary health care clinics in rural India: a randomized crossover trial
CONCLUSIONS: Provider-to-provider telemedicine, where nurses at Health and Wellness Centres connect with remote physicians to provide care for patients they would otherwise have referred to a tertiary facility, is a feasible and safe intervention. Telemedicine is less reliable than in-person care but a safe and effective alternative where in-person care cannot be provided. We found it most effective for managing high-burden primary health conditions such as hypertension, diabetes, and remote antenatal care. The use of a digital assistant to facilitate the collection of an evidence-based medical history can result in more e...
Source: Cancer Control - May 2, 2023 Category: Cancer & Oncology Authors: Neha Verma Bimal Buch Radha Taralekar Soumyadipta Acharya Source Type: research
Diagnostic concordance of telemedicine as compared to face-to-face care in primary health care clinics in rural India: a randomized crossover trial
CONCLUSIONS: Provider-to-provider telemedicine, where nurses at Health and Wellness Centres connect with remote physicians to provide care for patients they would otherwise have referred to a tertiary facility, is a feasible and safe intervention. Telemedicine is less reliable than in-person care but a safe and effective alternative where in-person care cannot be provided. We found it most effective for managing high-burden primary health conditions such as hypertension, diabetes, and remote antenatal care. The use of a digital assistant to facilitate the collection of an evidence-based medical history can result in more e...
Source: Rural Remote Health - May 2, 2023 Category: Rural Health Authors: Neha Verma Bimal Buch Radha Taralekar Soumyadipta Acharya Source Type: research
Diagnostic concordance of telemedicine as compared to face-to-face care in primary health care clinics in rural India: a randomized crossover trial
CONCLUSIONS: Provider-to-provider telemedicine, where nurses at Health and Wellness Centres connect with remote physicians to provide care for patients they would otherwise have referred to a tertiary facility, is a feasible and safe intervention. Telemedicine is less reliable than in-person care but a safe and effective alternative where in-person care cannot be provided. We found it most effective for managing high-burden primary health conditions such as hypertension, diabetes, and remote antenatal care. The use of a digital assistant to facilitate the collection of an evidence-based medical history can result in more e...
Source: Rural Remote Health - May 2, 2023 Category: Rural Health Authors: Neha Verma Bimal Buch Radha Taralekar Soumyadipta Acharya Source Type: research
Cluster immunotherapy
From almost the beginning of allergen immunotherapy (AIT), researchers have attempted to accelerate the initial dosing schedule. Just 19 years after Noon and Freeman described AIT in 1911, Freeman published the first “rush” AIT protocol. In 1954, his colleague, William Frankland, introduced controlled clinical trials of AIT. This was followed by double-blind randomized studies by Lowell and Franklin, and by Norman and Lichtenstein at Johns Hopkins University in the 1960s and 1970s, respectively. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - May 1, 2023 Category: Allergy & Immunology Authors: Jonathan Matz, David B.K. Golden Tags: Editorial Source Type: research
