Risk for CKD Progression After AKI
This study evaluated 3,150 racially and ethnically diverse CKD patients using a linear mixed-effects regression model that adjusted for factors, such as pre-AKI eGFR and proteinuria, to assess post-AKI eGFR trajectory with measurements at annual study visits. There were 612 episodes of AKI among 433 patients in a 3.9-year median follow-up. After adjusting for pre-AKI factors, AKI was not independently associated with worsened kidney function. The findings suggest that decline in renal function after AKI is more likely attributable to pre-AKI factors and, thus, the focus should shift towards early treatment of CKD and prote...
Source: The Hospitalist - February 1, 2024 Category: Hospital Management Authors: Ronda Whitaker Tags: In the Literature Nephrology (kidneys) Source Type: research
COVID-19 Testing and Vaccination Among US Older Adults with Vision Impairment: The National Health and Aging Trends Study 2021
. (Source: Ophthalmic Epidemiology)
Source: Ophthalmic Epidemiology - January 24, 2024 Category: Opthalmology Authors: Louay AlmidaniBonnielin K. SwenorJoshua R. EhrlichVarshini Varadaraja Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USAb Disability Health Research Center, Johns Hopkins University School of Nursing, Baltimore, Ma Source Type: research
Black community members, scientists object to plan to bury skulls from Philadelphia museum
For nearly 2 centuries, the skulls of 20 Black people who died in Philadelphia have formed part of the Morton Cranial Collection, now housed at the University of Pennsylvania (UPenn) Museum of Archaeology and Anthropology. Most of the skulls were collected by physical anthropologist Samuel Morton, who in the 1830s and ’40s
amassed hundreds of them
for studies he designed to identify supposed biological racial differences and scientifically prove what he believed to be the inferiority of nonwhite people. On 3 February,
the museum plans to lay the crania of 19 of the Black Philadelphians in the collection to...
Source: Science of Aging Knowledge Environment - January 23, 2024 Category: Geriatrics Source Type: research
Wisconsin bill to restrict pathogen studies worries scientists
A hearing this week in Wisconsin on a proposal to bar research that may make human pathogens more dangerous has scientists worried that such state bans would hamper a broad range of microbiology studies. Bills like Wisconsin’s could also conflict with or exceed new federal restrictions on so-called gain-of-function (GOF) research, due out any moment.
The Wisconsin bill is still early in the legislative process, and its prospects are uncertain. But the hearing gave a platform to a small, vocal group of scientists who want to forbid certain GOF studies. Several hold the controversial view that such research is to bla...
Source: Science of Aging Knowledge Environment - January 12, 2024 Category: Geriatrics Source Type: research
Fibroids and unexplained infertility treatment with epigallocatechin gallate: a natural compound in green tea (FRIEND) - protocol for a randomised placebo-controlled US multicentre clinical trial of EGCG to improve fertility in women with uterine fibroids
This study addresses the pressing need for non-hormonal, non-surgical treatment options for women with fibroids desiring pregnancy. Previous preclinical and clinical studies have shown that epigallocatechin gallate (EGCG) effectively reduces uterine fibroid size. We hypothesise that EGCG from green tea extract will shrink fibroids, enhance endometrial quality and increase pregnancy likelihood. To investigate this hypothesis, we initiated a National Institute of Child Health and Human Development Confirm-funded trial to assess EGCG’s efficacy in treating women with fibroids and unexplained infertility.
Methods and an...
Source: BMJ Open - January 12, 2024 Category: General Medicine Authors: Al-Hendy, A., Segars, J. H., Taylor, H. S., Gonzalez, F., Siblini, H., Zamah, M., Alkelani, H., Singh, B., Flores, V. A., Christman, G. M., Johnson, J. J., Huang, H., Zhang, H. Tags: Open access, Obstetrics & Gynaecology Obstetrics and gynaecology Source Type: research
Targeting the activin receptor 1C on CD4+ T cells for cancer immunotherapy
Volume 13, Issue 1, December 2024 . (Source: OncoImmunology)
Source: OncoImmunology - January 8, 2024 Category: Cancer & Oncology Authors: Ying ZhengAndriana LebidLiam ChungJuan FuXiaoxu WangAndrea OtrocolJelani C. ZarifHong YuNicolas J. LlosaDrew M. Pardolla Bloomberg~Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD, USAb Department of On Source Type: research
Certain Antidepressants May Increase Risk of Impulse Control Disorder in Parkinson ’s Patients
Taking serotonergic antidepressants such as serotonin and norepinephrine reuptake inhibitors (SNRIs) or selective serotonin reuptake inhibitors (SSRIs) may increase the risk of patients with Parkinson ’s disease developing impulse control disorder, astudy inThe American Journal of Geriatric Psychiatry has found.Impulse control disorders —which include a range of behaviors such as excessive gambling, spending, cleaning, and eating—are one of “the most challenging psychiatric syndromes” affecting people living with Parkinson’s disease, wrote Christopher B. Morrow, M.D., M.H.S., of the Johns Hopkins University Sch...
Source: Psychiatr News - January 5, 2024 Category: Psychiatry Tags: antidepressants gambling impulse control disorders Parkinson ' s disease SNRIs spending SSRIs The American Journal of Geriatric Psychiatry Source Type: research
Current status and development trends in CKD with frailty research from 2000 to 2021: a bibliometric analysis
CONCLUSIONS: This study presents a comprehensive bibliometric analysis of CKD and frailty research. Key findings highlight the current focus on early screening and assessment of frailty in CKD patients, as well as physical function interventions in frail patients.PMID:38178378 | DOI:10.1080/0886022X.2023.2292142 (Source: Renal Failure)
Source: Renal Failure - January 5, 2024 Category: Urology & Nephrology Authors: Guowei Yuan Yaqin Yang Yujie Lin Jiarong Lin Yuchi Wu Source Type: research
Current status and development trends in CKD with frailty research from 2000 to 2021: a bibliometric analysis
CONCLUSIONS: This study presents a comprehensive bibliometric analysis of CKD and frailty research. Key findings highlight the current focus on early screening and assessment of frailty in CKD patients, as well as physical function interventions in frail patients.PMID:38178378 | PMC:PMC10773684 | DOI:10.1080/0886022X.2023.2292142 (Source: Renal Failure)
Source: Renal Failure - January 5, 2024 Category: Urology & Nephrology Authors: Guowei Yuan Yaqin Yang Yujie Lin Jiarong Lin Yuchi Wu Source Type: research
Budgeting Tips: Keeping Division Finances on Track
Dr. Brotman
For a hospitalist, managing a budget shouldn’t be that much different than maintaining a household budget. “Ideally, you should know approximately how much income you’ll generate and how much you expect to spend on a monthly or quarterly basis, and these numbers need to roughly match up,” said Daniel J. Brotman, MD, FACP, MHM, director of the division of hospital medicine at Johns Hopkins Hospital, an urban academic medical center with more than 1,000 beds at Johns Hopkins University in Baltimore.
Dr. Bonsall
Most commonly, a hospital-medicine group leader who makes staffing decisions and creates sta...
Source: The Hospitalist - January 2, 2024 Category: Hospital Management Authors: Ronda Whitaker Tags: Business of Medicine Career Practice Management Source Type: research
Salmonella immunotherapy engineered with highly efficient tumor antigen coating establishes antigen-specific CD8+ T cell immunity and increases in antitumor efficacy with type I interferon combination therapy
Volume 13, Issue 1, December 2024 . (Source: OncoImmunology)
Source: OncoImmunology - December 28, 2023 Category: Cancer & Oncology Authors: Suyang WangMichelle ChengChao-Cheng ChenChia-Yu ChangYa-Chea TsaiJr-Ming YangTC WuChuan-Hsiang HuangChien-Fu Hunga Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USAb Department of Oncology, Johns Hopkins University S Source Type: research
Commentary on “Multimodal Exercise and Cognitive Training Program Improves Cognitive Function in Amnestic Mild Cognitive Impairment”
From the Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD. Send correspondence and reprint requests to George W. Rebok, PhD, Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, 624 North Broadway, Baltimore, MD 21205. Email: grebok1@jhu.edu. (Source: The American Journal of Geriatric Psychiatry)
Source: The American Journal of Geriatric Psychiatry - December 25, 2023 Category: Geriatrics Authors: George W. Rebok Tags: Editorial Source Type: research
“Innovative Diagnostic Methods,” a new section in the Journal of Clinical Microbiology
Journal of Clinical Microbiology, Ahead of Print. (Source: Journal of Clinical Microbiology)
Source: Journal of Clinical Microbiology - December 22, 2023 Category: Microbiology Authors: Patricia J. SimnerCarey-Ann D. BurnhamRomney M. HumphriesMelissa B. MillerElitza S. TheelAlexander J. McAdam1Department of Pathology, Johns Hopkins University, Baltimore, Maryland, USA2Pattern Bioscience, Austin, Texas, USA3Vanderbilt University Medical C Source Type: research
