Radiation unlocks the therapeutic potential of immune checkpoint blockers in lung cancer patients
. (Source: OncoImmunology)
Source: OncoImmunology - April 23, 2019 Category: Cancer & Oncology Authors: Eric C. Ko Lorenzo Galluzzi Source Type: research

Intravenous delivery of the toll-like receptor 7 agonist SC1 confers tumor control by inducing a CD8+ T cell response
. (Source: OncoImmunology)
Source: OncoImmunology - April 19, 2019 Category: Cancer & Oncology Authors: Fulvia Vascotto Jutta Petschenka Kerstin C. Walzer Mathias Vormehr Magdalena Brkic Stefan Strobl Roman R ösemann Mustafa Diken Sebastian Kreiter Özlem Türeci Ugur Sahin Source Type: research

Neo-antigen specific memory T-cell responses in healthy individuals
. (Source: OncoImmunology)
Source: OncoImmunology - April 19, 2019 Category: Cancer & Oncology Authors: Morten Orebo Holmstr öm Hans Carl Hasselbalch Mads Hald Andersen Source Type: research

The features of circulating and tumor-infiltrating γδ T cells in melanoma patients display critical perturbations with prognostic impact on clinical outcome
. (Source: OncoImmunology)
Source: OncoImmunology - April 17, 2019 Category: Cancer & Oncology Authors: Pauline Girard Julie Charles Camille Cluzel Emmanuelle Degeorges Olivier Manches Joel Plumas Florence De Fraipont Marie-Therese Leccia Stephane Mouret Laurence Chaperot Caroline Aspord Source Type: research

Targeting the C-terminus of galectin-9 induces mesothelioma apoptosis and M2 macrophage depletion
. (Source: OncoImmunology)
Source: OncoImmunology - April 17, 2019 Category: Cancer & Oncology Authors: Pietro Bertino Thomas A. Premeaux Tsuyoshi Fujita Brien K. Haun Michael P. Marciel Fukun W. Hoffmann Alan Garcia Haining Yiang Sandra Pastorino Michele Carbone Toshiro Niki John Berestecky Peter R. Hoffmann Lishomwa C. Ndhlovu Source Type: research

SALL4-mediated upregulation of exosomal miR-146a-5p drives T-cell exhaustion by M2 tumor-associated macrophages in HCC
. (Source: OncoImmunology)
Source: OncoImmunology - April 17, 2019 Category: Cancer & Oncology Authors: Chunlai Yin Qiuju Han Dongqing Xu Bingqing Zheng Xuemei Zhao Jian Zhang Source Type: research

Molecular and clinical characterization of CD163 expression via large-scale analysis in glioma
. (Source: OncoImmunology)
Source: OncoImmunology - April 17, 2019 Category: Cancer & Oncology Authors: Shasha Liu Chaoqi Zhang Nomathamsanqa Resegofetse Maimela Li Yang Zhen Zhang Yu Ping Lan Huang Yi Zhang Source Type: research

Development and validation of an immune-related gene pairs signature in colorectal cancer
. (Source: OncoImmunology)
Source: OncoImmunology - April 15, 2019 Category: Cancer & Oncology Authors: Jianping Wu Ying Zhao Juanwen Zhang Qianxia Wu Weilin Wang Source Type: research

Proteomes of exosomes from HPV(+) or HPV(-) head and neck cancer cells: differential enrichment in immunoregulatory proteins
. (Source: OncoImmunology)
Source: OncoImmunology - April 15, 2019 Category: Cancer & Oncology Authors: Sonja Ludwig Lukasz Marczak Priyanka Sharma Agata Abramowicz Marta Gawin Piotr Widlak Theresa L. Whiteside Monika Pietrowska Source Type: research

Depleting T regulatory cells by targeting intracellular Foxp3 with a TCR mimic antibody
. (Source: OncoImmunology)
Source: OncoImmunology - April 15, 2019 Category: Cancer & Oncology Authors: Tao Dao Sung Soo Mun Andrew C. Scott Casey A. Jarvis Tatyana Korontsvit Zhiyuan Yang Lianxing Liu Martin G. Klatt Manuel Guerreiro Annamalai Selvakumar Elliott J. Brea Claire Oh Cheng Liu David A. Scheinberg Source Type: research

Combined assessment of peritumoral Th1/Th2 polarization and peripheral immunity as a new biomarker in the prediction of BCG response in patients with high-risk NMIBC
. (Source: OncoImmunology)
Source: OncoImmunology - April 14, 2019 Category: Cancer & Oncology Authors: Roberto Mart ínez Gustavo Tapia Silvia De Muga Alba Hern ández Maria Gonz ález Cao Cristina Teixid ó Victor Urrea Elisabet Garc ía S ònia Pedreño-López Luis Ibarz Juli à Blanco Bonaventura Clotet Cecilia Cabrera Source Type: research

Daratumumab in combination with urelumab to potentiate anti-myeloma activity in lymphocyte-deficient mice reconstituted with human NK cells
. (Source: OncoImmunology)
Source: OncoImmunology - April 14, 2019 Category: Cancer & Oncology Authors: Maria C. Ochoa Elisabeth Perez-Ruiz Luna Minute Carmen O ñate Guiomar Perez Inmaculada Rodriguez Aintzane Zabaleta Diego Alignani Myriam Fernandez-Sendin Ascension Lopez Aura Muntasell Miguel F. Sanmamed Bruno Paiva Miguel Lopez-Botet Pedro Berraondo Ign Source Type: research

Interaction of tumor-associated macrophages and cancer chemotherapy
. (Source: OncoImmunology)
Source: OncoImmunology - April 14, 2019 Category: Cancer & Oncology Authors: Irina Larionova Nadezhda Cherdyntseva Tengfei Liu Marina Patysheva Militsa Rakina Julia Kzhyshkowska Source Type: research

Crizotinib – a tyrosine kinase inhibitor that stimulates immunogenic cell death
. (Source: OncoImmunology)
Source: OncoImmunology - April 13, 2019 Category: Cancer & Oncology Authors: Peng Liu Liwei Zhao Oliver Kepp Guido Kroemer Source Type: research

Tumor lysis with LTX-401 creates anticancer immunity
. (Source: OncoImmunology)
Source: OncoImmunology - April 13, 2019 Category: Cancer & Oncology Authors: Wei Xie Laura Mondrag ón Brynjar Mauseth Yan Wang Jonathan Pol Sarah L évesque Heng Zhou Takahiro Yamazaki Johannes J. Eksteen Laurence Zitvogel Baldur Sveinbj ørnsson Øystein Rekdal Oliver Kepp Guido Kroemer Source Type: research

Impaired circulating myeloid CD1c+ dendritic cell function in human glioblastoma is restored by p38 inhibition – implications for the next generation of DC vaccines
. (Source: OncoImmunology)
Source: OncoImmunology - April 13, 2019 Category: Cancer & Oncology Authors: Jason Adhikaree Hester Ann Franks Constantinos Televantos Poonam Vaghela Aanchal Preet Kaur David Walker Marc Schmitz Andrew Mark Jackson Poulam Manubhai Patel Source Type: research

A novel combination of chemotherapy and immunotherapy controls tumor growth in mice with a human immune system
. (Source: OncoImmunology)
Source: OncoImmunology - April 12, 2019 Category: Cancer & Oncology Authors: Aude Burlion Rodrigo N. Ramos Pukar KC K élhia Sendeyo Aur élien Corneau Christine M énétrier-Caux Eliane Piaggio Daniel Olive Christophe Caux Gilles Marodon Source Type: research

Interleukin-1 β provided by KIT-competent mast cells is required for KRAS-mutant lung adenocarcinoma
. (Source: OncoImmunology)
Source: OncoImmunology - April 11, 2019 Category: Cancer & Oncology Authors: Ioannis Lilis Giannoula Ntaliarda Vassilios Papaleonidopoulos Georgia A Giotopoulou Maria Oplopoiou Antonia Marazioti Magda Spella Sebastian Marwitz Torsten Goldmann Vasiliki Bravou Ioanna Giopanou Georgios T. Stathopoulos Source Type: research

Oncolytic virus immunotherapy induces immunogenic cell death and overcomes STING deficiency in melanoma
. (Source: OncoImmunology)
Source: OncoImmunology - April 8, 2019 Category: Cancer & Oncology Authors: Praveen K. Bommareddy Andrew Zloza Samuel D. Rabkin Howard L. Kaufman Source Type: research

Prognostic value of tumor-infiltrating lymphocytes in melanoma: a systematic review and meta-analysis
. (Source: OncoImmunology)
Source: OncoImmunology - April 3, 2019 Category: Cancer & Oncology Authors: Qiaofen Fu Nan Chen Chunlei Ge Ruilei Li Zhen Li Baozhen Zeng Chunyan Li Ying Wang Yuanbo Xue Xin Song Heng Li Gaofeng Li Source Type: research

Trial watch: Dietary interventions for cancer therapy
. (Source: OncoImmunology)
Source: OncoImmunology - April 3, 2019 Category: Cancer & Oncology Authors: Sarah L évesque Jonathan G. Pol Gladys Ferrere Lorenzo Galluzzi Laurence Zitvogel Guido Kroemer Source Type: research

The role of NK cells and CD39 in the immunological control of tumor metastases
. (Source: OncoImmunology)
Source: OncoImmunology - April 2, 2019 Category: Cancer & Oncology Authors: Haiyan Zhang Dipti Vijayan Xian-Yang Li Simon C. Robson Nishamol Geetha Michele W. L. Teng Mark J. Smyth Source Type: research

Clinical significance of CD8+ T cell immunoreceptor with Ig and ITIM domains+ in locally advanced gastric cancer treated with SOX regimen after D2 gastrectomy
. (Source: OncoImmunology)
Source: OncoImmunology - April 1, 2019 Category: Cancer & Oncology Authors: Weiwei Tang Xiongxiong Pan Di Han Dawei Rong Minghui Zhang Lulu Yang Jie Ying Hua Guan Ziyi Chen Xuehao Wang Source Type: research

Toll-like receptor 3 acts as a suppressor gene in breast cancer initiation and progression: a two-stage association study and functional investigation
. (Source: OncoImmunology)
Source: OncoImmunology - March 30, 2019 Category: Cancer & Oncology Authors: Lei Fan Peng Zhou Qi Hong Ao-Xiang Chen Guang-Yu Liu Ke-Da Yu Zhi-Ming Shao Source Type: research

Neoantigens retention in patient derived xenograft models mediates autologous T cells activation in ovarian cancer
. (Source: OncoImmunology)
Source: OncoImmunology - March 30, 2019 Category: Cancer & Oncology Authors: Muzamil Yaqub Want Anna Konstorum Ruea-Yea Huang Vaibhav Jain Satoko Matsueda Takemasa Tsuji Amit Lugade Kunle Odunsi Richard Koya Sebastiano Battaglia Source Type: research

Metabolic enzymes expressed by cancer cells impact the immune infiltrate
. (Source: OncoImmunology)
Source: OncoImmunology - March 30, 2019 Category: Cancer & Oncology Authors: Gautier Stoll Margerie Kremer Normal Bloy Adrien Joseph Maria Castedo Guillaume Meurice Christophe Klein Lorenzo Galluzzi Judith Michels Guido Kroemer Source Type: research

APC germline hepatoblastomas demonstrate cisplatin-induced intratumor tertiary lymphoid structures
. (Source: OncoImmunology)
Source: OncoImmunology - March 28, 2019 Category: Cancer & Oncology Authors: Guillaume Morcrette Theo Z Hirsch Elise Badour Jill Pilet Stefano Caruso Julien Calderaro Yoann Martin Sandrine Imbeaud Eric Letouz é Sandra Rebouissou Sophie Branchereau Sophie Taque Christophe Chardot Catherine Guettier Jean-Yves Scoazec Monique Fabre Source Type: research

Oncolytic viruses: how “lytic” must they be for therapeutic efficacy?
. (Source: OncoImmunology)
Source: OncoImmunology - March 28, 2019 Category: Cancer & Oncology Authors: Maria Eugenia Davola Karen Louise Mossman Source Type: research

Immune mediator expression signatures are associated with improved outcome in ovarian carcinoma
. (Source: OncoImmunology)
Source: OncoImmunology - March 28, 2019 Category: Cancer & Oncology Authors: Mano Nakamura Heather J. Bax Daniele Scotto Elmira Amiri Souri Sam Sollie Robert J. Harris Niklas Hammar Goran Walldius Anna Winship Sharmistha Ghosh Ana Montes James F. Spicer Mieke Van Hemelrijck Debra H. Josephs Katie E. Lacy Sophia Tsoka Sophia N. Kar Source Type: research

Potentiating vascular-targeted photodynamic therapy through CSF-1R modulation of myeloid cells in a preclinical model of prostate cancer
. (Source: OncoImmunology)
Source: OncoImmunology - March 28, 2019 Category: Cancer & Oncology Authors: Souhil Lebdai Mathieu Gigoux Ricardo Alvim Alexander Somma Karan Nagar Abdel Rahmene Azzouzi Olivier Cussenot Taha Merghoub Jedd D. Wolchok Avigdor Scherz Kwanghee Kim Jonathan Coleman Source Type: research

Serum cytokine levels as predictive biomarkers of benefit from ipilimumab in small cell lung cancer
. (Source: OncoImmunology)
Source: OncoImmunology - March 27, 2019 Category: Cancer & Oncology Authors: Max Hardy-Werbin Pedro Rocha Oriol Arpi Álvaro Taus Lara Nonell Xavier Dur án Xavier Villanueva Deborah Joseph-Pietras Luke Nolan Sarah Danson Richard Griffiths Miguel Lopez-Botet Ana Rovira Joan Albanell Christian Ottensmeier Edurne Arriola Source Type: research

Fusobacterium nucleatum supresses anti-tumor immunity by activating CEACAM1
. (Source: OncoImmunology)
Source: OncoImmunology - March 27, 2019 Category: Cancer & Oncology Authors: Chamutal Gur Naseem Maalouf Amjad Shhadeh Orit Berhani Bernhard B. Singer Gilad Bachrach Ofer Mandelboim Source Type: research

Autoantibody status in systemic sclerosis patients defines both cancer risk and survival with ANA negativity in cases with concomitant cancer having a worse survival
. (Source: OncoImmunology)
Source: OncoImmunology - March 25, 2019 Category: Cancer & Oncology Authors: Abdulla Watad Dennis McGonagle Nicola L. Bragazzi Shmuel Tiosano Doron Comaneshter Yehuda Shoenfeld Arnon D. Cohen Howard Amital Source Type: research

Localization-associated immune phenotypes of clonally expanded tumor-infiltrating T cells and distribution of their target antigens in rectal cancer
. (Source: OncoImmunology)
Source: OncoImmunology - March 25, 2019 Category: Cancer & Oncology Authors: Livius Penter Kerstin Dietze Julia Ritter Maria Fernanda Lammoglia Cobo Josefin Garmshausen Felix Aigner Lars Bullinger Holger Hackstein Sandra Wienzek-Lischka Thomas Blankenstein Michael Hummel Klaus Dornmair Leo Hansmann Source Type: research

TCR sequencing analysis of cancer tissues and tumor draining lymph nodes in colorectal cancer patients
. (Source: OncoImmunology)
Source: OncoImmunology - March 22, 2019 Category: Cancer & Oncology Authors: Tatsuo Matsuda Eisaku Miyauchi Yu-Wen Hsu Satoshi Nagayama Kazuma Kiyotani Makda Zewde Jae-Hyun Park Taigo Kato Makiko Harada Shimpei Matsui Masashi Ueno Kazumasa Fukuda Nobuaki Suzuki Shoichi Hazama Hiroaki Nagano Hiroya Takeuchi Wickii T. Vigneswaran Yu Source Type: research

WISP1 is associated to advanced disease, EMT and an inflamed tumor microenvironment in multiple solid tumors
. (Source: OncoImmunology)
Source: OncoImmunology - March 22, 2019 Category: Cancer & Oncology Authors: Pierre-Olivier Gaudreau Sylvie Clairefond Caleb A. Class Pierre-Luc Boulay Pavel Chrobak Bertrand Allard Feryel Azzi Sandra Pommey Kim-Anh Do Fred Saad Dominique Trudel Marian Young John Stagg Source Type: research

Inhibition of PI3K pathway increases immune infiltrate in muscle-invasive bladder cancer
. (Source: OncoImmunology)
Source: OncoImmunology - March 16, 2019 Category: Cancer & Oncology Authors: Edith Borcoman Philippe De La Rochere Wilfrid Richer Sophie Vacher Walid Chemlali Cl émentine Krucker Nanour Sirab Francois Radvanyi Yves Allory G éraldine Pignot Nicolas Barry de Longchamps Diane Damotte Didier Meseure Christine Sedlik Ivan Bieche Elia Source Type: research

SpCas9-expression by tumor cells can cause T cell-dependent tumor rejection in immunocompetent mice
. (Source: OncoImmunology)
Source: OncoImmunology - March 16, 2019 Category: Cancer & Oncology Authors: Reham Ajina Danielle Zamalin Annie Zuo Maha Moussa Marta Catalfamo Sandra A. Jablonski Louis M. Weiner Source Type: research

Inhibition of PI3K pathway increases immune infiltrate in muscle-invasive bladder cancer
. (Source: OncoImmunology)
Source: OncoImmunology - March 16, 2019 Category: Cancer & Oncology Authors: Edith Borcoman Philippe De La Rochere Wilfrid Richer Sophie Vacher Walid Chemlali Cl émentine Krucker Nanour Sirab Francois Radvanyi Yves Allory G éraldine Pignot Nicolas Barry de Longchamps Diane Damotte Didier Meseure Christine Sedlik Ivan Bieche Elia Source Type: research

SpCas9-expression by tumor cells can cause T cell-dependent tumor rejection in immunocompetent mice
. (Source: OncoImmunology)
Source: OncoImmunology - March 16, 2019 Category: Cancer & Oncology Authors: Reham Ajina Danielle Zamalin Annie Zuo Maha Moussa Marta Catalfamo Sandra A. Jablonski Louis M. Weiner Source Type: research

Sub-cutaneous Fat Mass measured on multislice computed tomography of pretreatment PET/CT is a prognostic factor of stage IV non-small cell lung cancer treated by nivolumab
. (Source: OncoImmunology)
Source: OncoImmunology - March 6, 2019 Category: Cancer & Oncology Authors: Geoffrey Popinat St éphanie Cousse Lucas Goldfarb St éphanie Becker Isabelle Gardin Mathieu Sala ün S ébastien Thureau Pierre Vera Florian Guisier Pierre Decazes Source Type: research

Increased bone marrow SUVmax on 18F-FDG PET is associated with higher pelvic treatment failure in patients with cervical cancer treated by chemoradiotherapy and brachytherapy
. (Source: OncoImmunology)
Source: OncoImmunology - March 6, 2019 Category: Cancer & Oncology Authors: Romain-David Seban Charlotte Robert Laurent Dercle Randy Yeh Ariane Dunant Sylvain Reuze Antoine Schernberg Roger Sun Fabien Mignot Marie Terroir Martin Schlumberger Christine Haie-Meder Cyrus Chargari Eric Deutsch Source Type: research

Sub-cutaneous Fat Mass measured on multislice computed tomography of pretreatment PET/CT is a prognostic factor of stage IV non-small cell lung cancer treated by nivolumab
. (Source: OncoImmunology)
Source: OncoImmunology - March 6, 2019 Category: Cancer & Oncology Authors: Geoffrey Popinat St éphanie Cousse Lucas Goldfarb St éphanie Becker Isabelle Gardin Mathieu Sala ün S ébastien Thureau Pierre Vera Florian Guisier Pierre Decazes Source Type: research

Efficacy and safety of immune checkpoint inhibitors in advanced gastric or gastroesophageal junction cancer: a systematic review and meta-analysis
. (Source: OncoImmunology)
Source: OncoImmunology - March 5, 2019 Category: Cancer & Oncology Authors: Cong Chen Fan Zhang Ning Zhou Yan-Mei Gu Ya-Ting Zhang Yi-Di He Ling Wang Lu-Xi Yang Yang Zhao Yu-Min Li Source Type: research

Timing of neoadjuvant immunotherapy in relation to surgery is crucial for outcome
. (Source: OncoImmunology)
Source: OncoImmunology - March 1, 2019 Category: Cancer & Oncology Authors: Jing Liu Jake S. O ’Donnell Juming Yan Jason Madore Stacey Allen Mark J. Smyth Michele W. L. Teng Source Type: research

Synergistic inhibition of pancreatic cancer with anti-PD-L1 and c-Myc inhibitor JQ1
. (Source: OncoImmunology)
Source: OncoImmunology - March 1, 2019 Category: Cancer & Oncology Authors: Yu Pan Qinglin Fei Ping Xiong Jianyang Yang Zheyang Zhang Xianchao Lin Minggui Pan Fengchun Lu Heguang Huang Source Type: research

Timing of neoadjuvant immunotherapy in relation to surgery is crucial for outcome
. (Source: OncoImmunology)
Source: OncoImmunology - March 1, 2019 Category: Cancer & Oncology Authors: Jing Liu Jake S. O ’Donnell Juming Yan Jason Madore Stacey Allen Mark J. Smyth Michele W. L. Teng Source Type: research

Synergistic inhibition of pancreatic cancer with anti-PD-L1 and c-Myc inhibitor JQ1
. (Source: OncoImmunology)
Source: OncoImmunology - March 1, 2019 Category: Cancer & Oncology Authors: Yu Pan Qinglin Fei Ping Xiong Jianyang Yang Zheyang Zhang Xianchao Lin Minggui Pan Fengchun Lu Heguang Huang Source Type: research