Precirrhotic Primary Biliary Cholangitis with Portal Hypertension: Bile Duct Injury Correlate
CONCLUSIONS: : Approximately 24.2% of precirrhotic PBC patients have PH, which is histologically related to the injury of bile ducts. High alkaline phosphatase levels, low white blood cell counts, high Mayo scores, and high FIB-4 index values are associated with increased risk of precirrhotic PBC with PH.PMID:38623061 | DOI:10.5009/gnl230468 (Source: Gut and Liver)
Source: Gut and Liver - April 16, 2024 Category: Gastroenterology Authors: Yi-Fan Hu Shun-Xin Li Hong-Li Liu Zhi-Xiang Du Shuang-Shuang Wang Miao-Yang Chen Li Wang Qing-Fang Xiong Yan-Dan Zhong Du-Xian Liu Yong-Feng Yang Source Type: research
Efficacy and safety of antibiotics for treatment of leptospirosis: a systematic review and network meta-analysis
ConclusionsFindings recommend that leptospirosis patients be treated with antibiotics, which significantly reduced the leptospirosis defervescence time. Cephalosporins, doxycycline, and penicillin are suggested, and azithromycin may be a suitable alternative for drug-resistant cases.Systematic review registrationPROSPERO CRD42022354938. (Source: Systematic Reviews)
Source: Systematic Reviews - April 16, 2024 Category: International Medicine & Public Health Source Type: research
A Rare Case of Benign Recurrent Intrahepatic Cholestasis Initially Diagnosed in Middle-age
CONCLUSION: The comprehensive diagnosis of a middle-aged male patient with BRIC-2, which involved extensive radiological, hematological, and genetic investigations, informed a tailored tapering prednisone regimen, highlighting the importance of personalized medicine in managing atypical presentations of this rare cholestatic disorder.PMID:38607191 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 12, 2024 Category: Complementary Medicine Authors: Fang Liu Wei Li Ming-Gang Zhang Zhen-Mei Song Xiao-di Wang Xiu-Hong Wang Shi-Yu Du Source Type: research
A Rare Case of Benign Recurrent Intrahepatic Cholestasis Initially Diagnosed in Middle-age
CONCLUSION: The comprehensive diagnosis of a middle-aged male patient with BRIC-2, which involved extensive radiological, hematological, and genetic investigations, informed a tailored tapering prednisone regimen, highlighting the importance of personalized medicine in managing atypical presentations of this rare cholestatic disorder.PMID:38607191 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 12, 2024 Category: Complementary Medicine Authors: Fang Liu Wei Li Ming-Gang Zhang Zhen-Mei Song Xiao-di Wang Xiu-Hong Wang Shi-Yu Du Source Type: research
A Rare Case of Benign Recurrent Intrahepatic Cholestasis Initially Diagnosed in Middle-age
CONCLUSION: The comprehensive diagnosis of a middle-aged male patient with BRIC-2, which involved extensive radiological, hematological, and genetic investigations, informed a tailored tapering prednisone regimen, highlighting the importance of personalized medicine in managing atypical presentations of this rare cholestatic disorder.PMID:38607191 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 12, 2024 Category: Complementary Medicine Authors: Fang Liu Wei Li Ming-Gang Zhang Zhen-Mei Song Xiao-di Wang Xiu-Hong Wang Shi-Yu Du Source Type: research
Prevalence, perinatal outcomes and factors associated with neonatal sepsis in Nigeria
CONCLUSIONS: Neonatal sepsis remains a critical challenge in neonatal care, underscored by its high prevalence and mortality rate. The identification of maternal and neonatal risk factors underscores the importance of improved access to education and employment for women and targeted interventions in antenatal and intrapartum care.PMID:38602158 | DOI:10.1111/1471-0528.17824 (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - April 11, 2024 Category: OBGYN Authors: Chinyere Ukamaka Onubogu Uchenna Ekwochi Ijeoma Obumneme-Anyim Linda Nneka Nwokeji-Onwe George Uchenna Eleje Nnabuike Okechukwu Ojiegbe Ifeanyichukwu Uzoma Ezebialu Eziamaka Pauline Ezenkwele Emily Akuabia Nzeribe Uchenna Anthony Umeh Innocent Anayochukwu Source Type: research
Prevalence, perinatal outcomes and factors associated with neonatal sepsis in Nigeria
CONCLUSIONS: Neonatal sepsis remains a critical challenge in neonatal care, underscored by its high prevalence and mortality rate. The identification of maternal and neonatal risk factors underscores the importance of improved access to education and employment for women and targeted interventions in antenatal and intrapartum care.PMID:38602158 | DOI:10.1111/1471-0528.17824 (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - April 11, 2024 Category: OBGYN Authors: Chinyere Ukamaka Onubogu Uchenna Ekwochi Ijeoma Obumneme-Anyim Linda Nneka Nwokeji-Onwe George Uchenna Eleje Nnabuike Okechukwu Ojiegbe Ifeanyichukwu Uzoma Ezebialu Eziamaka Pauline Ezenkwele Emily Akuabia Nzeribe Uchenna Anthony Umeh Innocent Anayochukwu Source Type: research
Curcuma wenyujin rhizomes extract ameliorates lipid accumulation
In conclusion, CWP rich in sesquiterpenes reduces the accumulation of lipids in vivo and in vitro by improving lipid metabolism and activating autophagy.PMID:38604260 | DOI:10.1016/j.fitote.2024.105957 (Source: Fitoterapia)
Source: Fitoterapia - April 11, 2024 Category: Biochemistry Authors: Hong Wang Lijia Chen Ruiyu Zhang Guanying Zhang Jingwen Liu Fujiang Guo Source Type: research
Prevalence, perinatal outcomes and factors associated with neonatal sepsis in Nigeria
CONCLUSIONS: Neonatal sepsis remains a critical challenge in neonatal care, underscored by its high prevalence and mortality rate. The identification of maternal and neonatal risk factors underscores the importance of improved access to education and employment for women and targeted interventions in antenatal and intrapartum care.PMID:38602158 | DOI:10.1111/1471-0528.17824 (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - April 11, 2024 Category: OBGYN Authors: Chinyere Ukamaka Onubogu Uchenna Ekwochi Ijeoma Obumneme-Anyim Linda Nneka Nwokeji-Onwe George Uchenna Eleje Nnabuike Okechukwu Ojiegbe Ifeanyichukwu Uzoma Ezebialu Eziamaka Pauline Ezenkwele Emily Akuabia Nzeribe Uchenna Anthony Umeh Innocent Anayochukwu Source Type: research
Curcuma wenyujin rhizomes extract ameliorates lipid accumulation
In conclusion, CWP rich in sesquiterpenes reduces the accumulation of lipids in vivo and in vitro by improving lipid metabolism and activating autophagy.PMID:38604260 | DOI:10.1016/j.fitote.2024.105957 (Source: Fitoterapia)
Source: Fitoterapia - April 11, 2024 Category: Biochemistry Authors: Hong Wang Lijia Chen Ruiyu Zhang Guanying Zhang Jingwen Liu Fujiang Guo Source Type: research
Prevalence, perinatal outcomes and factors associated with neonatal sepsis in Nigeria
CONCLUSIONS: Neonatal sepsis remains a critical challenge in neonatal care, underscored by its high prevalence and mortality rate. The identification of maternal and neonatal risk factors underscores the importance of improved access to education and employment for women and targeted interventions in antenatal and intrapartum care.PMID:38602158 | DOI:10.1111/1471-0528.17824 (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - April 11, 2024 Category: OBGYN Authors: Chinyere Ukamaka Onubogu Uchenna Ekwochi Ijeoma Obumneme-Anyim Linda Nneka Nwokeji-Onwe George Uchenna Eleje Nnabuike Okechukwu Ojiegbe Ifeanyichukwu Uzoma Ezebialu Eziamaka Pauline Ezenkwele Emily Akuabia Nzeribe Uchenna Anthony Umeh Innocent Anayochukwu Source Type: research
Successful treatment of severe splenic lymphoma ‑associated hemophagocytic syndrome by splenectomy and subsequent chemotherapy: A case report
Oncol Lett. 2024 Mar 22;27(5):222. doi: 10.3892/ol.2024.14355. eCollection 2024 May.ABSTRACTHemophagocytic lymphohistiocytosis (HLH) represents a fatal immunopathology derived from excessive inflammatory reactions. In particular, lymphoma-associated hemophagocytic syndrome (LAHS) is associated with a dismal prognosis. The current study presented a challenging case of splenic LAHS. A 71-year-old man presented with fatigue and anorexia. Laboratory test results revealed anemia, thrombocytopenia, lactate dehydrogenase elevation and markedly elevated levels of ferritin (6,210 ng/ml) and soluble interleukin 2 receptor (sIL-2R; 1...
Source: Oncology Letters - April 9, 2024 Category: Cancer & Oncology Authors: Hideyuki Masui Maki Shindo Yuta Inoue Maki Sugiyama Atsushi Ueda Takero Shindo Kae Okoshi Koichi Kinoshita Source Type: research
Clinical characteristics of choledochal cysts with intrahepatic bile duct dilatations: an observational study
CONCLUSION: Most IHBDs can recover to normal postoperatively in a short time, and proactive treatment is recommended for CC patients with IHBD dilatation for significant abnormal liver functions.PMID:38586557 | PMC:PMC10995834 | DOI:10.4174/astr.2024.106.4.225 (Source: Annals of Surgical Treatment and Research)
Source: Annals of Surgical Treatment and Research - April 8, 2024 Category: Surgery Authors: Ken Chen Shuhao Zhang Duote Cai Yuebin Zhang Yi Jin Wenjuan Luo Zongwei Huang Di Hu Zhigang Gao Source Type: research
