Compound improves cardiac function in mice with genetic heart defect, MU study finds
(University of Missouri-Columbia) Congenital heart disease is the most common form of birth defect. Researchers from the University of Missouri recently found success using a drug to treat laboratory mice with one form of congenital heart disease, hypertrophic cardiomyopathy -- a weakening of the heart caused by abnormally thick muscle. By suppressing a faulty protein, the researchers reduced the thickness of the mice's heart muscles and improved their cardiac functioning. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - February 20, 2014 Category: Biology Source Type: news
Developing the sports physical of the future
Every few years there’s news coverage on a young, assumed-healthy athlete, who suddenly dies on the field or court. Sometimes the tragedy even happens right in front of the players’ teammates, coaches and parents. Later, the autopsy often reveals a previously undetected heart condition like hypertrophic cardiomyopathy, leaving many to wonder, “Why didn’t we know about this problem sooner?”
To help, Boston Children’s Hospital researchers are working on revamping current methods to screen for potential heart problems in young athletes—without adding huge expenses or time burdens to exist...
Source: Thrive, Children's Hospital Boston - January 27, 2014 Category: Pediatrics Authors: Tripp Underwood Tags: All posts Diseases & conditions Health & wellness Parenting Research Screening Sports & exercise Division of Sports Medicine electroencephalograms (EEG) sudden death in young athletes Source Type: news
Sports medicine physical of future could help athletes 'ESCAPE' sudden cardiac death
A young athlete in seemingly excellent health dies suddenly from a previously undetected cardiovascular condition such as hypertrophic cardiomyopathy in nearly every US state annually. Although these conditions can be detected using electrocardiography (ECG) during a screening exam, the American Heart Association recommends against routine use of ECG, because it has a high false-positive rate. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - January 23, 2014 Category: Science Source Type: news
Advances of Cardiovascular MRI in Hypertrophic CardiomyopathyAdvances of Cardiovascular MRI in Hypertrophic Cardiomyopathy
Hypertrophic cardiomyopathy is a genetic disease characterized by abnormal myocardial hypertrophy, which can lead to a wide clinical spectrum, including sudden cardiac death and heart failure. Find out the best ways to diagnose it. Future Cardiology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 15, 2013 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news
ICDs in Hypertrophic CardiomyopathyICDs in Hypertrophic Cardiomyopathy
Just how many lifesaving therapies are ICDs delivering in patients with hypertrophic cardiomyopathy? How many therapies are inappropriate? American Heart Journal (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 17, 2013 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news
Heart disease caused by reductive stress may be prevented by disrupting an antioxidant pathway
University of Utah researchers have found that deficiency of an antioxidant response protein called nuclear erythroid-2 like factor-2 (Nrf2) delays or prevents hypertrophic cardiomyopathy, a type of a heart failure in which the heart muscle grows abnormally thick. This new finding, published in the journal Cardiovascular Research, suggests that restoring the normal balance of reduction-oxidation chemical reactions in the body could prevent heart disease and other conditions caused by reductive stress... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 15, 2013 Category: Consumer Health News Tags: Heart Disease Source Type: news
Targeting genetics of hypertrophic cardiomyopathy: silencing sudden death
Hypertrophic cardiomyopathy (HCM), a disease in which cardiac muscle thickens, weakening the heart, can be prevented from developing for several months in mice by reducing production of a mutant protein, according to a new study by researchers at Harvard Medical School. The work takes a first step toward being able to treat or prevent the leading cause of sudden death in athletes and sudden heart-related death in people under 30 in the United States. "There's really no treatment for HCM right now... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 7, 2013 Category: Consumer Health News Tags: Cardiovascular / Cardiology Source Type: news
Sequencing of Hypertrophic and Dilated Cardiomyopathy GenesSequencing of Hypertrophic and Dilated Cardiomyopathy Genes
Is next generation sequencing for cardiomyopathy genes ready for implementation in a diagnostic setting? Journal of Medical Genetics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 19, 2013 Category: Consumer Health News Tags: Business of Medicine Journal Article Source Type: news
Factors at Dx Predict Outcome in Children With Bad Hearts (CME/CE)
(MedPage Today) -- The causes of disease, its subtypes, and risk factors present at the time a child is diagnosed with hypertrophic cardiomyopathy can help predict the likelihood of death or need for heart transplantation, a registry study showed. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - September 6, 2013 Category: Cardiology Source Type: news
Scientists Pinpoint Which Kids with Heart Muscle Disease Are in Most Danger
Key risk factors measured at diagnosis can guide treatment for cases of hypertrophic cardiomyopathy
Source: HealthDay
Related MedlinePlus Pages: Cardiomyopathy, Children's Health (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - September 4, 2013 Category: Consumer Health News Source Type: news
Scientists identify key predictors of death and transplantation in children with heart muscle disease
US scientists have identified key risk factors that predict which children with hypertrophic cardiomyopathy, the most common cause of sudden death in young people, are at greatest risk of death or need for heart transplant - information that could help physicians figure out who will benefit most from transplant surgery... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - September 4, 2013 Category: Consumer Health News Tags: Heart Disease Source Type: news
Researchers present first risk calculator for pediatric hypertrophic cardiomyopathy in Lancet study
A decade-long quest to understand why some children with hypertrophic cardiomyopathy do well under medical management while others die of heart failure or sudden cardiac death showed some babies are at highest risk for dismal outcomes and yielded a risk calculator cardiologists can use to evaluate which of them diagnosed with the rare condition should be considered for a heart transplant in the immediate future. Inspired by the story and advocacy of a mother who lost two infant sons to the disorder characterized by a thickening of the heart walls, the Miller School's Steven E. Lipshultz, M... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - September 3, 2013 Category: Consumer Health News Tags: Pediatrics / Children's Health Source Type: news
Risk factors help predict outcomes for children with rare heart condition
(NIH/National Heart, Lung and Blood Institute) A long-term study of children with a complex heart condition called hypertrophic cardiomyopathy found that risk factors identified at diagnosis helped predict outcomes. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - September 3, 2013 Category: Global & Universal Source Type: news
Foundation to host 5th International Cardiology Summit
(Minneapolis Heart Institute Foundation) The Hypertrophic Cardiomyopathy (HCM) Center of the Minneapolis Heart Institute Foundation, directed by Dr. Barry J. Maron, will host the fifth international summit on HCM: A Contemporary Treatable Disease on Sept. 27-29 at the Hyatt Regency Hotel in Minneapolis, Minn. The conference, represented by noted HCM physicians and researchers from around the globe, is an accredited conference dedicated to the presentation of the latest and most innovative methods for diagnosis and treatment of HCM. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 20, 2013 Category: Global & Universal Source Type: news
ICDs in High-Risk Patients With Hypertrophic CardiomyopathyICDs in High-Risk Patients With Hypertrophic Cardiomyopathy
Implanted cardioverter-defibrillators (ICDs) can prevent sudden cardiac death in high-risk patients with hypertrophic cardiomyopathy, but as in other populations, the devices come at a cost. Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 1, 2013 Category: Consumer Health News Tags: Internal Medicine News Source Type: news
