Heart cells ’ environment a potentially major factor in heart disease
New research shows the role that a diseased extracellular matrix plays in the progression of the genetic condition hypertrophic cardiomyopathy. (Source: Yale Science and Health News)
Source: Yale Science and Health News - July 24, 2019 Category: Universities & Medical Training Source Type: news
Hypertrophic Cardiomyopathy, Diabetes, and the Test of Time Hypertrophic Cardiomyopathy, Diabetes, and the Test of Time
How does diabetes mellitus impact the clinical profile and outcome of patients with hypertrophic cardiomyopathy? How might it affect disease management?European Heart Journal (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 15, 2019 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news
Guidelines for HOCM Treatment: A Moving Target? Guidelines for HOCM Treatment: A Moving Target?
The optimal treatment for symptomatic hypertrophic obstructive cardiomyopathy continues to be a subject of debate among surgeons and cardiologists.European Heart Journal (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 10, 2019 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news
Published Study Supports MyoKardia ’s Wrist-Worn Biosensor
MyoKardia’s said data on its wrist-worn digital health device was published in an article titled, “Machine Learning Detection of Obstructive Hypertrophic Cardiomyopathy (oHCM) Using a Wearable Biosensor,†in the Nature Partner Journal, Digital Medicine.
The South San Francisco-based company said results from an exploratory study provided encouraging evidence of the potential for a wrist-worn biosensor to screen for obstructive hypertrophic cardiomyopathy.
The study demonstrated that continuous monitoring using a wrist-worn photoplethysmography (PPG) digital health devic...
Source: MDDI - June 24, 2019 Category: Medical Devices Authors: MDDI Staff Tags: Business Cardiovascular Source Type: news
New Technology Saves Those With Genetic Heart Disease
BOSTON (CBS) – We’ve all heard the tragic tales of teens and young adults collapsing while playing sports from a rare heart condition. Now, a father-son team in Boston has developed a strategy to save those patients most at risk.
“It was devastating.” Kevin Whelan recalled the moment he learned his oldest brother, Kyle, collapsed and died. He was only 26 years old.
Kyle had hypertrophic cardiomyopathy, or HCM, a genetic disease of the heart and the most common cause of sudden death in otherwise healthy young people.
But Kyle wasn’t the only one in the family with it. His father and all three sons had ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - May 22, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health Healthwatch Syndicated Local Dr. Mallika Marshall Hypertrophic Cardiomyopathy Source Type: news
New Strategy Saving Those With Genetic Heart Disease
BOSTON (CBS) – We’ve all heard the tragic tales of teens and young adults collapsing while playing sports from a rare heart condition. Now, a father-son team in Boston has developed a strategy to save those patients most at risk.
“It was devastating.” Kevin Whelan recalled the moment he learned his oldest brother, Kyle, collapsed and died. He was only 26 years old.
Kyle had hypertrophic cardiomyopathy, or HCM, a genetic disease of the heart and the most common cause of sudden death in otherwise healthy young people.
But Kyle wasn’t the only one in the family with it. His father and all three sons had ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - May 22, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health Healthwatch Syndicated Local Dr. Mallika Marshall Hypertrophic Cardiomyopathy Source Type: news
Heart scan 'could pick up signs of sudden death risk'
Researchers used detailed images of the heart to look for signs of hypertrophic cardiomyopathy. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - May 20, 2019 Category: Consumer Health News Source Type: news
Breakthrough as scientists can now spot leading cause of cardiac arrest in young people
Oxford University scientists have found a way to use MRI scanners to picture the arrangement of muscle fibres in the heart to pick out warning signs of hypertrophic cardiomyopathy. (Source: the Mail online | Health)
Source: the Mail online | Health - May 20, 2019 Category: Consumer Health News Source Type: news
The ECG and the Phenotypic Expression of HCM The ECG and the Phenotypic Expression of HCM
What is the significance of marked ECG abnormalities in an individual with a positive genotype for hypertrophic cardiomyopathy?European Heart Journal (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 8, 2019 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news
Continuous ECG Changes Over 8 Years in an Athlete With HCM Continuous ECG Changes Over 8 Years in an Athlete With HCM
This case report reveals that abnormal ECG findings may precede the symptoms and signs of hypertrophic cardiomyopathy for many years.Journal of Medical Case Reports (Source: Medscape Radiology Headlines)
Source: Medscape Radiology Headlines - May 8, 2019 Category: Radiology Tags: Cardiology Journal Article Source Type: news
A promising new treatment for infants with Noonan syndrome
(University of Montreal) Infants less than six months old with Noonan Syndrome, hypertrophic cardiomyopathy and congestive heart failure normally have a poor prognosis, with a one-year survival rate of 34%. In the new study, doctors used Trametinib to try to treat NS in two patients.They observed dramatic improvement of clinical and cardiac status in the patients only three months after treatment. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 30, 2019 Category: International Medicine & Public Health Source Type: news
What Is the Most Common Type of Cardiomyopathy?
Discussion
Barth syndrome is characterized by a dilated cardiomyopathy, proximal skeletal muscle weakness, neutropenia and short stature that usually presents at birth or soon after. It is a rare X-linked recessive disease process caused by mutations in the TAZ gene. The TAZ gene codes for tafazzin which alters cardiolipin in mitochondria. Characteristic facies can be seen especially in infancy including a tall and broad forehead, prominent chin and full cheeks, larger ears, and deep-set eyes. Most patients present at birth or soon afterwards but some may not until later in life. Life expectancy is reduced with many childr...
Source: PediatricEducation.org - February 25, 2019 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
Scientists unravel genetic basis of hypertrophic cardiomyopathy in Finns
(University of Eastern Finland) One third of hypertrophic cardiomyopathy cases in Finland are caused by one of the four major mutations, a new study from the University of Eastern Finland and Kuopio University Hospital shows. Overall, 40 percent of patients carried a specific or a likely mutation causing the disease, and 20 percent were carriers of a rare gene mutation whose role in the disease remains unknown. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 22, 2019 Category: International Medicine & Public Health Source Type: news
Bad brakes
(Harvard Medical School) A study in human and mouse heart cells identifies a faulty molecular brake in the most common form of hypertrophic cardiomyopathy, a leading cause of sudden cardiac death in young people and athletes and the most common genetic disease of the heart The faulty brake, found about a quarter of all genetic mutations in hypertrophic cardiomyopathy, interferes with the heart muscle's ability to contract and relax,.Treatment with a chemical compound successfully restores normal contractility and relaxation in human heart cells (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 28, 2019 Category: International Medicine & Public Health Source Type: news
Hypertrophic Cardiomyopathy: A to Z with Richard Bach, MD
(MedPage Today) -- Andrew Perry, MD, interviews specialty center director (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - December 28, 2018 Category: Urology & Nephrology Source Type: news
