Keeping the heart's engine in sync: Contractions' efficiency depends on critical protein
(University of Vermont) Researchers have identified a remarkable protein that helps choreograph the highly specific series of events that ensure the heart beats consistently and accurately. Called myosin-binding protein C (cMyBP-C), this protein performs its masterpiece inside the sarcomere, a part of the heart muscle tissue that is one-fiftieth the diameter of a human hair. Trillions or more sarcomeres must contract simultaneously in order for the heart to maintain its beat. Problems with this protein can cause sudden death via a condition called hypertrophic cardiomyopathy. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 20, 2015 Category: Global & Universal Source Type: news
New hope for understanding sudden cardiac arrest
New biosciences research could point the way to greater understanding of the heart mutations that cause sudden cardiac arrest. Hypertrophic cardiomyopathy is a genetic condition that one in 500 people carry and is a leading cause of sudden cardiac arrest in young athletes. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - January 20, 2015 Category: Science Source Type: news
Why do only some people with hereditary heart disease experience symptoms?
In addition to gene mutations, environmental stress plays a key role in the development of the heart disease hypertrophic cardiomyopathy, researchers have found for the first time. As many as 500,000 people in the United States have a heritable and potentially fatal heart disease called hypertrophic cardiomyopathy. The disease can cause irregular heartbeats, heart valve problems, heart failure and, in rare cases, sudden cardiac death in young people. But some people who carry gene mutations that cause hypertrophic cardiomyopathy never experience symptoms. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - January 5, 2015 Category: Science Source Type: news
Gadolinium Magnetic Resonance and Hypertrophic CardiomyopathyGadolinium Magnetic Resonance and Hypertrophic Cardiomyopathy
Find out how imaging may help predict sudden cardiac death in hypertrophic cardiomyopathy. Heart (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 29, 2014 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news
AHA: Losartan Disappoints in Hypertrophic Cardiomyopathy (CME/CE)
(MedPage Today) -- ARB no better than placebo for reducing left ventricular hypertrophy. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - November 20, 2014 Category: Cardiology Source Type: news
New ESC Guidelines on hypertrophic cardiomyopathy
The 2014 ESC Guidelines on the diagnosis and management of hypertrophic cardiomyopathy (HCM) are presented for the first time at this congress. The guidelines underscore the multidisciplinary approach to the disease, including imaging, genetics, percutaneous and surgical interventions, device implantations, and pharmacology.
Topics:
Myocardial Disease, Heart Failure (HF) (Source: ESC News and Press)
Source: ESC News and Press - September 1, 2014 Category: Cardiology Source Type: news
Sudden death predictor identifies ICD candidates in new ESC Guidelines
(European Society of Cardiology) A new sudden death predictor for patients with hypertrophic cardiomyopathy identifies candidates for implantable cardioverter defibrillators (ICDs) in ESC Guidelines published today. They are presented at ESC Congress by Task Force Chairperson professor Perry Elliott. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 30, 2014 Category: Global & Universal Source Type: news
ESC introduces five new practice guidelines, with a range of tools for everyday application
This year's ESC Congress will see the launch of five new ESC Guidelines: Non-Cardiac Surgery, Acute Pulmonary Embolism, Hypertrophic Cardiomyopathy, Aortic Diseases and Myocardial Revascularization. The guidelines were developed by expert Task Forces under the governance of the ESC’s Committee for Practice Guidelines. All in all, more than 100 experts are involved in the development of each one. Read more & access the Guidelines (Source: ESC News and Press)
Source: ESC News and Press - August 25, 2014 Category: Cardiology Source Type: news
News for the EORP Cardiomyopathy and Myocarditis Registry
On behalf of the Cardiomyopathy Executive Committee of the EURObservational Research Programme (EORP), we are pleased to announce the launch of the Long-Term Cardiomyopathies and Myocarditis Registry and invite you to contact us in order to participate in this exciting endeavour. The registry is open to adult and paediatric cardiology units. Data will be collected on the following disorders: hypertrophic cardiomyopathy; dilated cardiomyopathy; arrhythmogenic right ventricular cardiomyopathy; restrictive cardiomyopathy; and clinically suspected myocarditis. (Source: ESC News and Press)
Source: ESC News and Press - July 1, 2014 Category: Cardiology Source Type: news
Vitamin K Antagonist in Hypertrophic Cardiomyopathy and AFVitamin K Antagonist in Hypertrophic Cardiomyopathy and AF
Get the latest update on the importance of stroke prophylaxis with oral anticoagulants in patients with cardiomyopathy. Future Cardiology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 20, 2014 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news
Heart Condition Rarely Assessed in Pre-Sports Checkups
(MedPage Today) -- BOSTON -? Routine testing before participating in sports infrequently looks for hypertrophic cardiomyopathy -? a condition that can lead to sudden cardiac death, particularly among blacks, researchers said here. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - May 29, 2014 Category: Cardiology Source Type: news
Novel Mitochondrial Mutation and Hypertrophic CardiomyopathyNovel Mitochondrial Mutation and Hypertrophic Cardiomyopathy
The association of a novel mitochondrial mutation with hypertrophic cardiomyopathy provides a new insight into the pathogenesis of HCM. Journal of Medical Genetics (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - April 2, 2014 Category: Pathology Tags: Pathology & Lab Medicine Journal Article Source Type: news
Thursday consumer health tips
Fruit juice: Good or bad for kids? Menopause symptoms: Lifestyle tips offer relief Hypertrophic cardiomyopathy New therapies sought for triple negative breast cancer Testosterone level: Can you boost it naturally? (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - March 27, 2014 Category: Databases & Libraries Source Type: news
Drummer Beating Heart Disease (pkg)
All Justin ever wanted to do was play drums in a rock and roll band, but a serious heart problem, hypertrophic cardiomyopathy, silenced his music. With doubts about living to see his 24th birthday, he went to Mayo Clinic to find help and hope. [TRT 3:30] Journalists: The full package, animation and additional b-roll are available in the downloads. [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - March 24, 2014 Category: Databases & Libraries Source Type: news
Compound improves cardiac function in mice with genetic heart defect, study finds
Congenital heart disease is the most common form of birth defect. Researchers recently found success using a drug to treat laboratory mice with one form of congenital heart disease, hypertrophic cardiomyopathy -- a weakening of the heart caused by abnormally thick muscle. By suppressing a faulty protein, the researchers reduced the thickness of the mice's heart muscles and improved their cardiac functioning. Because of the role the protein plays in signaling heart growth, the authors believe the research could be translated in the future into improved treatments for other types of heart disease, such as damage caused by he...
Source: ScienceDaily Headlines - February 20, 2014 Category: Science Source Type: news
