Study links viral infections to Alzheimer ’s, Parkinson’s—with many caveats
A massive data mining study has found numerous associations between common viruses like the flu and devastating neurodegenerative disorders such as Parkinson’s disease, Alzheimer’s disease, and amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig’s disease). The findings expand on previous research linking individual viruses to neurological diseases. But experts caution that the study, which relied on electronic medical records rather than biological samples, merely describes correlations and doesn’t prove causation. Still, it’s “really exciting,” says Kristen Funk, a neuroimmunologist who studi...
Source: ScienceNOW - January 19, 2023 Category: Science Source Type: news

Notes from the Field: Expanded Laboratory Testing for Varicella - Minnesota, 2016-2023
This report describes expanded laboratory testing for varicella by the Minnesota Department of Health. (Source: CDC Morbidity and Mortality Weekly Report)
Source: CDC Morbidity and Mortality Weekly Report - January 6, 2023 Category: American Health Tags: Chickenpox (Varicella Disease) MMWR Morbidity & Mortality Weekly Report Shingles (Herpes Zoster) Source Type: news

Facial paralysis after intraoral anesthetic injection: A systematic review
Dent Med Probl . 2022 Oct-Dec;59(4):617-627. Abstract Many complications can occur after the injection of local intraoral anesthetics (ILIA) before dental intervention. Facial paralysis (FP) is one of these complications. The purpose of this study was to systematically analyze the association between ILIA and FP. A systematic review was carried out taking into account the methodology of the Cochrane Handbook for Systematic Reviews of Interventions and the PRISMA statement. The search strategy used " Palsy AND Facial " and " Paralysis AND Facial " as search terms. The ScienceDirect, PubMed and Scopus databases were searche...
Source: Dental Technology Blog - January 6, 2023 Category: Dentistry Source Type: news

Africa: Dormant Shingles Virus in Your Neurons Can Increase Risk of Stroke - New Research Identified a Potential Culprit
[The Conversation Africa] Over 90% of the world population has the virus that causes chickenpox lying dormant in their nervous system. Most people contract the varicella zoster virus, or VZV, when they get chickenpox as children. For around a third of these people, this same virus will reactivate years later and cause shingles, also called herpes zoster. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - December 21, 2022 Category: African Health Source Type: news

Science ’s 2022 Breakthrough of the Year: A telescope’s golden eye sees the universe anew
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Source: ScienceNOW - December 15, 2022 Category: Science Source Type: news

Herpes Zoster Linked to Increased Risk for Cardiovascular Disease Events
FRIDAY, Dec. 2, 2022 -- Herpes zoster (HZ) is associated with an elevated long-term risk for a cardiovascular event, according to a study published online Nov. 16 in the Journal of the American Heart Association. Sharon G. Curhan, M.D., from Brigham... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - December 2, 2022 Category: Pharmaceuticals Source Type: news

Fear of falling as a potential complication of Ramsay Hunt syndrome in older adults: a case report - Chou CC, Lo YT, Su HC, Chang CM.
BACKGROUND: Fear of falling (FOF) is a common and major health concern in older adults. The consequences of FOF include reduced physical performance, social activity, and health-related quality of life. Ramsay Hunt syndrome (RHS) is a herpes zoster-related... (Source: SafetyLit)
Source: SafetyLit - November 30, 2022 Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news

Mayo Clinic Q and A: Shingles -- not just a band of blisters
DEAR MAYO CLINIC: A friend recently went through a bout of shingles. I really don't know much about this condition, but I know it was painful. How do you get it? Is there a treatment or vaccine for it? ANSWER: Shingles, also known as herpes zoster, is a common condition caused by the varicella-zoster virus, which also causes chickenpox. Not everyone who has had chickenpox will develop shingles. However, after years of lying dormant in nerve tissue… (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - November 28, 2022 Category: Databases & Libraries Source Type: news

Shingles Associated with Increased Risk for Stroke, Heart Attack
Study of more than 200,000 people demonstrated that herpes zoster (shingles) is associated with an almost 30% higher long-term risk of a major cardiovascular event (Source: BWH News)
Source: BWH News - November 22, 2022 Category: Hospital Management Source Type: news

Large U.S. Study Finds No Link Between COVID Vaccine and Shingles
(MedPage Today) -- No association was detected between COVID-19 vaccination and herpes zoster infection in a database study involving more than 2 million individuals in the U.S. Using a self-controlled risk interval (SCRI) analysis, the risk of... (Source: MedPage Today Dermatology)
Source: MedPage Today Dermatology - November 16, 2022 Category: Dermatology Source Type: news

What Are the Potential Benefits and Risks of Premasticated Foods?
Discussion Premastication is the prechewing of foods or medicines by another person before feeding to an infant. It is also used to pretaste or temperature test foods. It was a common practice for millennia, especially before modern food technology, as a way to transition an infant from a solely liquid based diet to a mixed diet mainly of solid food. Rates of premastication vary, with less developed countries having an increased incidence/prevalence (up to 50%) but it is not uncommon in developed countries (in the US 14% is reported). Saliva is also used to clean other people, treat cuts/itches or insect bites as well. Pla...
Source: PediatricEducation.org - November 14, 2022 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Obesity Protects Against Genital Herpes in Mice, Study Finds
A high-fat diet induced changes to the animals’ vaginal microbiomes that boosted survival after exposure to the virus. (Source: The Scientist)
Source: The Scientist - November 11, 2022 Category: Science Tags: News & Opinion Source Type: news

New TREMFYA ® (guselkumab) Post-Hoc Analysis Reveals Early Efficacy Predicted Longer-Term Efficacy And Sustained Achievement Among A Diverse Active Psoriatic Arthritis Patient Population
SPRING HOUSE, PENNSYLVANIA, November 11, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced a new post-hoc analysis of the Phase 3 DISCOVER program (DISCOVER-1 and DISCOVER-2) evaluating TREMFYA® (guselkumab) in adult patients with active psoriatic arthritis (PsA), which showed that early skin and enthesitis responsesa,b predicted longer-term clinical response,c including disease remission, at week 52.1 TREMFYA is the first fully human selective interleukin (IL)-23 inhibitor therapy approved in the U.S. for adults with moderate to severe plaque psoriasis (PsO) and adults with active PsA...
Source: Johnson and Johnson - November 11, 2022 Category: Pharmaceuticals Tags: Latest News Source Type: news

New TREMFYA ® (guselkumab) Post-Hoc Analysis Reveals Active Psoriatic Arthritis Patients With Early Efficacy Had Meaningful Long-Term Improvement in Health-Related Quality of Life
SPRING HOUSE, PENNSYLVANIA, November 10, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced a new post-hoc analysis of the Phase 3 DISCOVER-2 study that show early (week 8) clinical improvementsa of most measures (joint and skin disease, enthesitis and dactylitis) in adult patients with active psoriatic arthritis (PsA) treated with TREMFYA® (guselkumab) were associated with meaningful improvements in health-related quality of life (HRQoL) (measured by EQ-5D)b from year one (week 52) through year two (week 100).1 TREMFYA is the first fully human selective interleukin (IL)-23 inhibitor th...
Source: Johnson and Johnson - November 10, 2022 Category: Pharmaceuticals Tags: Latest News Source Type: news

Viral Shedding Common After First-Episode Genital HSV-1 Infection
MONDAY, Oct. 31, 2022 -- Genital viral shedding is frequent after first-episode genital herpes simplex virus type 1 (HSV-1) infection, particularly among those with primary infection, according to a study published online Oct. 22 in the Journal of... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - October 31, 2022 Category: Pharmaceuticals Source Type: news