Drug for rare disorder shows promise for treating herpes viruses
(University of Illinois at Chicago) New research shows that the antiviral activity of the drug -- called phenylbutyrate, or PBA -- was even better when used along with acyclovir, a common HSV-1 treatment. When used in combination, less acyclovir is needed to effectively suppress the virus compared to acyclovir alone -- this is important because acyclovir is also known to have toxic side effects in the kidneys. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - December 7, 2020 Category: Infectious Diseases Source Type: news
Viral epitope profiling of COVID-19 patients reveals cross-reactivity and correlates of severity
Understanding humoral responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is critical for improving diagnostics, therapeutics, and vaccines. Deep serological profiling of 232 coronavirus disease 2019 (COVID-19) patients and 190 pre–COVID-19 era controls using VirScan revealed more than 800 epitopes in the SARS-CoV-2 proteome, including 10 epitopes likely recognized by neutralizing antibodies. Preexisting antibodies in controls recognized SARS-CoV-2 ORF1, whereas only COVID-19 patient antibodies primarily recognized spike protein and nucleoprotein. A machine learning model trained on VirScan data...
Source: ScienceNOW - November 26, 2020 Category: Science Authors: Shrock, E., Fujimura, E., Kula, T., Timms, R. T., Lee, I.-H., Leng, Y., Robinson, M. L., Sie, B. M., Li, M. Z., Chen, Y., Logue, J., Zuiani, A., McCulloch, D., Lelis, F. J. N., Henson, S., Monaco, D. R., Travers, M., Habibi, S., Clarke, W. A., Caturegli, Tags: Immunology, Microbiology, Online Only r-articles Source Type: news
Eye Herpes
Title: Eye HerpesCategory: Diseases and ConditionsCreated: 1/31/2005 12:00:00 AMLast Editorial Review: 11/17/2020 12:00:00 AM (Source: MedicineNet Eyesight General)
Source: MedicineNet Eyesight General - November 17, 2020 Category: Opthalmology Source Type: news
Are We Getting Closer to a Herpes Vaccine?
MONDAY, Nov. 16, 2020 -- Scientists are reporting early success with an experimental herpes vaccine that uses a genetically modified version of the virus.
The gene edit prevents the virus from performing its normal evasive maneuver: hiding... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - November 16, 2020 Category: General Medicine Source Type: news
Your Corneas May Be Safe From COVID: Study
Although viruses such as herpes simplex can infect the cornea and Zika has been found in corneal tissue and tears, this does not appear to be the case with COVID-19, according to researchers from Washington University School of Medicine in St. Louis. (Source: WebMD Health)
Source: WebMD Health - November 6, 2020 Category: Consumer Health News Source Type: news
Your Corneas May Be Safe From COVID: Study
FRIDAY, Nov. 6, 2020 -- A new study suggests that COVID-19 doesn ' t infect the eye ' s cornea.
Although viruses such as herpes simplex can infect the cornea and Zika has been found in corneal tissue and tears, this does not appear to be the case with... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - November 6, 2020 Category: General Medicine Source Type: news
Vaccine shows promise against herpes virus
(University of Nebraska-Lincoln) A genetically edited form of a herpes simplex virus has outperformed a leading vaccine candidate in a new study published in Nature Vaccines. When challenged with a virulent strain of the sexually transmitted HSV-2, vaccinated guinea pigs displayed fewer genital lesions, less viral replication and less of the viral shedding that most readily spreads infection. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 6, 2020 Category: International Medicine & Public Health Source Type: news
Would I Know If I Had Herpes
? (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - November 5, 2020 Category: General Medicine Source Type: news
Cornea appears to resist infection from novel coronavirus
(Washington University School of Medicine) Some doctors have worried that the novel coronavirus may be able to infect people by getting into their eyes. Viruses such as herpes simplex can infect the eye's cornea and Zika virus has been found in corneal tissue and tears, but new research from Washington University School of Medicine in St. Louis suggests the cornea can resist infection from SARS-CoV-2. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - November 3, 2020 Category: Infectious Diseases Source Type: news
Vacuna contra la culebrilla (herpes z óster)
Es la m ás eficaz que ha existido y previene una infección muy desagradable. ... Entonces, ¿por qué no se vacunan más adultos? ... Es causado por el mismo virus que la varicela, varicela-zóster, que... (Source: AARP.org News)
Source: AARP.org News - October 24, 2020 Category: American Health Source Type: news
Shingrix Effective in Older Adults With Autoimmune Diseases Shingrix Effective in Older Adults With Autoimmune Diseases
The CDC recommends that adults aged at least 50 years receive two doses of Shingrix to help prevent reoccurrence of herpes zoster.Medscape Medical News (Source: Medscape Internal Medicine Headlines)
Source: Medscape Internal Medicine Headlines - October 6, 2020 Category: Internal Medicine Tags: Rheumatology News Source Type: news
What Are the Symptoms of Herpes Simplex Keratitis?
Discussion
Herpes simplex virus (HSV) infections are common with an estimated 50% of the US population being infected by age 30, and with latent infection harboring in the trigeminal nerve in 100% of people by age 60 years. HSV infections can cause a vesicular or pustular skin rash that is painful, burning or pruritic and also flu-like symptoms with fever, chills, headache, and fatigue. HSV can also be asymptomatic.
To laymen, herpes simplex viruses cause “cold sores,” but to health care personnel, herpes causes many systemic infections including eczema herpeticum, folliculitis, herpes gladiatorum, whitlow, e...
Source: PediatricEducation.org - October 5, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
How Easy Is It to Get Herpes
? (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - September 24, 2020 Category: General Medicine Source Type: news
What Are Systemic Disease Causes of Oral Ulcers?
Discussion
Oral ulcers are common problems seen by dentists but pediatricians also see them. Usually families have are concerned because they are painful and acute. Ulcers are sometime noticed by the physician and not the family as in the case of herpangina or hand-foot and mouth disease. Chronic or recurrent ulcerations present less commonly and therefore it may be more difficult to determine their etiology. Many of the systemic disease causes of oral ulcers are overall infrequent and/or not common in the pediatric age range.
Ulcers can be classified in several ways but acute ulcers are usually painful and last less tha...
Source: PediatricEducation.org - September 21, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
What Does Genital Herpes Look Like
? (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - September 18, 2020 Category: General Medicine Source Type: news
