Worm infestation in intestine has a remote effect on viral defenses
(University of Bonn) Infection with parasitic intestinal worms (helminths) can apparently cause sexually transmitted viral in-fections to be much more severe elsewhere in the body. This is shown by a study led by the Universities of Cape Town and Bonn. According to the study, helminth-infected mice developed significantly more severe symptoms after infection with a genital herpes viruses (Herpes Simplex Virus). The researchers suspect that these results can also be transferred to humans. The results have now appeared in the journal Cell Host& Microbe. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 15, 2021 Category: International Medicine & Public Health Source Type: news
First patient-derived organoid model for cervical cancer
(Hubrecht Institute) Researchers from the group of Hans Clevers developed the first patient-derived organoid model for cervical cancer. They also modelled the healthy human cervix using organoids. The researchers used the platform to study sexually transmitted infections for a herpes virus. The model can potentially also be used to study human papillomavirus (HPV), which is one of the main causes of cervical cancer. The results will be published in Cell Stem Cell on the 13th of April, 2021. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 13, 2021 Category: Cancer & Oncology Source Type: news
Deadly Brain Tumor: Survival Extended by Oncolytic Virus Product Deadly Brain Tumor: Survival Extended by Oncolytic Virus Product
Improved survival was seen in a small trial in which a genetically engineered version of herpes simplex virus was infused directly into high-grade gliomas.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - April 12, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news
Differences in herpes virus symptoms may relate to variations in strain gene expression
(Penn State) Why do some people with cold sores around their lips experience painful lesions, while others have no symptoms at all, yet still spread the virus? A new study conducted at Penn State finds that these differences could be due to variations in the way certain strains of herpes simplex (HSV-1) -- the virus that causes cold sores, as well as genital herpes -- activate gene expression in neurons. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - March 29, 2021 Category: Infectious Diseases Source Type: news
New Phase 3 Data Show First-in-Class TREMFYA ® (guselkumab) Achieved Complete Skin Clearance and Favorable Joint Efficacy in Adult Patients with Active Psoriatic Arthritis (PsA) Through Two Years
SPRING HOUSE, PENNSYLVANIA, March 16, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced long-term data from the Phase 3 DISCOVER-2a study showing that the skin clearance, joint symptom relief, and safety of TREMFYA® (guselkumab) previously demonstrated through 24 weeks and one year (Week 52) in adults with active psoriatic arthritis (PsA) continued through two years (Week 112).1,2 These findings also confirmed that the robust efficacy TREMFYA demonstrated in patients at Week 24 on physical function, physical aspects of health-related quality of life, and resolution of enthesitisb and d...
Source: Johnson and Johnson - March 16, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news
What Causes Herpes Cold Sores? New Research
Scientists may have discovered why cold sores caused by herpes simplex virus (HSV) are triggered by stress, illness and sunburn. (Source: WebMD Health)
Source: WebMD Health - February 17, 2021 Category: Consumer Health News Source Type: news
What Causes Herpes Cold Sore Flare-Ups? New Study Offers Clues
WEDNESDAY, Feb. 17, 2021 -- Scientists may have discovered why cold sores caused by herpes simplex virus (HSV) are triggered by stress, illness and sunburn.
The finding could lead to new ways to prevent recurring cold sores and herpes-related eye... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - February 17, 2021 Category: General Medicine Source Type: news
What Causes Herpes Cold Sore Flare-Ups? New Study Offers Clues
Title: What Causes Herpes Cold Sore Flare-Ups? New Study Offers CluesCategory: Health NewsCreated: 2/17/2021 12:00:00 AMLast Editorial Review: 2/17/2021 12:00:00 AM (Source: MedicineNet Skin General)
Source: MedicineNet Skin General - February 17, 2021 Category: Dermatology Source Type: news
Are Cold Sores the Same as Herpes?
Title: Are Cold Sores the Same as Herpes?Category: Diseases and ConditionsCreated: 2/16/2021 12:00:00 AMLast Editorial Review: 2/16/2021 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - February 16, 2021 Category: Nutrition Source Type: news
Cold sores: Discovery reveals how stress, illness and even sunburn trigger flareups
(University of Virginia Health System) The finding could lead to new ways to prevent cold sores and herpes-related eye disease from reoccurring, the researchers report. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - February 11, 2021 Category: Infectious Diseases Source Type: news
How Do You Get Herpes Zoster
? (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - February 9, 2021 Category: General Medicine Source Type: news
What is a Lipschultz Ulcer?
Discussion
Acute genital ulcers (AGU) are much less common in sexually-naive women than sexually experienced or active women. The differential diagnosis of AGU is large. For sexually active women Herpes simplex virus is the most common cause. Sexually transmitted infections are also included in this differential. In addition to the pain, AGUs can cause distress for the patient and family as possible sexual abuse must be considered.
The differential diagnosis of AGU in non-sexually active women includes:
Aphthosis
Lipschutz ulcer
Idiopathic
Autoimmune or inflammatory diseases
Behcet disease
Bullous pemphigoid
Inflammato...
Source: PediatricEducation.org - February 8, 2021 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
Cancer Plagues California Sea Lions, With Implications for Humans
FRIDAY, Feb. 5, 2021 -- A virus-linked cancer killing California sea lions is sounding a chilling alarm for mankind.
Exposure to environmental toxins significantly boosts risk for the herpes-like cancer, which was discovered in sea lions in... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - February 5, 2021 Category: General Medicine Source Type: news
T cells linked to myelin implicated in MS-like disease in monkeys
(Oregon Health& Science University) Scientists have uncovered new clues implicating a type of herpes virus as the cause of a central nervous system disease in monkeys that's similar to multiple sclerosis in people. By linking two specific T cells to the loss of myelin, scientists say the new study opens the possibility of developing an antiviral therapy that could be especially useful for newly diagnosed cases of multiple sclerosis. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 15, 2021 Category: International Medicine & Public Health Source Type: news
Development of a new method for decoding viral genes
(The Institute of Medical Science, The University of Tokyo) A research team led by Professor Yasushi Kawaguchi of the Institute of Medical Science, the University of Tokyo, developed a new decoding method for viral genes that can easily and quickly obtain even non-canonical genetic information. Using this new decoding method, they identified nine novel proteins encoded by herpes simplex virus type 1(HSV-1) and found that one of them, piUL49, is a pathogenic factor that specifically controls the onset of herpes encephalitis . (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 7, 2020 Category: International Medicine & Public Health Source Type: news
