Bacteria in our brains
Microbial communities are found at many different sites on the human body, including nasal passages, oral cavities, skin, gastrointestinal tract, and urogenital tract. These commensal microbes shape the immune and metabolic status of the host and play important roles in human health and disease. The brain is one organ that has been assumed to be sterile in the healthy host, but this is probably not true – apparently we have bacteria in our brains!
This remarkable observation came about as part of a study to determine if AIDS, a disease known to damage the blood-brain barrier, might lead to the presence of bacteria in...
Source: virology blog - June 28, 2013 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Information This Week in Microbiology alpha-proteobacteria brain microbiome viral virus Source Type: blogs
Paget's disease if Nipple- Review
Clinical:
Approximately 1%–3% of women with adenocarcinoma of the
breast have Paget disease. Clinically-Paget disease has common dermatitis-like appearance,
as originally described in 1874, when Sir James Paget recorded that such
lesions may resemble “ordinary chronic eczema” or present as nipple erosion or
ulceration. Paget disease often has a deceptively banal clinical morphology but
should lead the list of differential diagnoses when evaluating unilateral
lesions of the nipple–areola complex in adults.
Paget disease presenting with nipple erosion.
Most women with the histopathologic finding o...
Source: Oncopathology - June 28, 2013 Category: Pathologists Tags: Breast Biopsy Procedure Breast Carcinoma vs. Pulmonary Adenocarcinoma a common misdiagnosis. Source Type: blogs
Paget's disease if Nipple- Review
Clinical:Approximately 1% –3% of women with adenocarcinoma of the breast have Paget disease. Clinically-Paget disease has common dermatitis-like appearance, as originally described in 1874, when Sir James Paget recorded that such lesions may resemble “ordinary chronic eczema” or present as nipple erosion or ulceration. Paget disease often has a deceptively banal clinical morphology but should lead the list of differential diagnoses when evaluating unilateral lesions of the nipple–areola complex in adults.Paget disease presenting with nipple erosion. Most women with the histopathologic finding of Paget disease ...
Source: Oncopathology - June 28, 2013 Category: Cancer & Oncology Tags: a common misdiagnosis. breast Breast Biopsy Procedure Breast Carcinoma vs. Pulmonary Adenocarcinoma Source Type: blogs
Paget's disease if Nipple- Review
Clinical:Approximately 1% –3% of women with adenocarcinoma of the breast have Paget disease. Clinically-Paget disease has common dermatitis-like appearance, as originally described in 1874, when Sir James Paget recorded that such lesions may resemble “ordinary chronic eczema” or present as nipple erosion or ulceration. Paget disease often has a deceptively banal clinical morphology but should lead the list of differential diagnoses when evaluating unilateral lesions of the nipple–areola complex in adults.Paget disease presenting with nipple erosion. Most women with the histopathologic finding of Paget disease ...
Source: Oncopathology - June 28, 2013 Category: Cancer & Oncology Tags: a common misdiagnosis. breast Breast Biopsy Procedure Breast Carcinoma vs. Pulmonary Adenocarcinoma Source Type: blogs
Media release: Herpes zoster as a marker of underlying malignancy
Open Medicine
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FOR IMMEDIATE RELEASE
Herpes zoster as a marker of underlying malignancy
Today, Open Medicine <http://www.openmedicine.ca/> published a study assessing whether a diagnosis of herpes zoster is a risk factor for subsequent malignancy.
Both herpes zoster—more commonly known as shingles--and cancer are associated with suppression of the immune system; however, it has been unclear what, if any, association there is between an earlier finding of shingles and later diagnosis of a malignant tumor.
“This is, we believe, the largest study to date examining th...
Source: Open Medicine Blog - - June 18, 2013 Category: Medical Publishers Authors: Carlyn Zwarenstein Source Type: blogs
NICE fever guidelines for kids
Fever is the most common presentation to Paeds ED and it can be difficult to identify a focus. This causes us (me anyway) a great deal of concern. After 10 years in paediatrics it still is the one thing weighing at the back of my mind – how to identify the child with the life-threatening bacterial infection amongst all the viral illnesses. NICE have updated their guidance in May 2013.
Often, they make it easy for us. Knowing how to recognise a sick child comes pretty early on in your paediatric experience. It’s the ones that don’t look desperately sick that are tricky. Let’s be honest, at 4am, every hot...
Source: Life in the Fast Lane - May 28, 2013 Category: Emergency Medicine Doctors Authors: Tessa Davis Tags: Emergency Medicine Featured Pediatrics fever Guidelines NICE NICE guidelines paediatric Source Type: blogs
NICE fever guidelines for kids
Fever is the most common presentation to Paeds ED and it can be difficult to identify a focus. This causes us (me anyway) a great deal of concern. After 10 years in paediatrics it still is the one thing weighing at the back of my mind – how to identify the child with the life-threatening bacterial infection amongst all the viral illnesses. NICE have updated their guidance in May 2013.
Often, they make it easy for us. Knowing how to recognise a sick child comes pretty early on in your paediatric experience. It’s the ones that don’t look desperately sick that are tricky. Let’s be honest, at 4am, every hot...
Source: Life in the Fast Lane - May 28, 2013 Category: Emergency Medicine Doctors Authors: Tessa Davis Tags: Emergency Medicine Featured Pediatrics fever Guidelines NICE NICE guidelines paediatric Source Type: blogs
TWiV 234: Live in Denver
Episode #234 of the science show This Week in Virology was recorded before an audience at the 2013 General Meeting of the American Society for Microbiology in Denver, Colorado. Vincent and Kathy spoke with Nels Elde and Tom Shenk about their work on the evolution of virus-host conflict and how viruses influence the cell metabolome.
You can find TWiV #234 at www.twiv.tv. (Source: virology blog)
Source: virology blog - May 26, 2013 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology cytomegalovirus evolution genomic accordion herpes simplex virus metabolome poxvirus red queen conflict viral Source Type: blogs
A Life-Course Approach to Vaccination Can Drive Healthy Aging
As life spans increase and birth-rates decrease, the world’s population is aging. From 2000 to 2025, the over-60 demographic segment will double from 600 million to almost 1.2 billion. By 2050, it will nearly double again, surpassing two billion and accounting for an incredible 22% of the total global population. A society this “old” has never before existed, and it is a social, ethical, and economic imperative to keep older adults healthy and engaged. It is timely for the global public health community to re-align its thinking, policies and activities to this new demographic reality.
Organizations at national and g...
Source: Health Affairs Blog - May 22, 2013 Category: Health Medicine and Bioethics Commentators Authors: Michael Hodin, Javier Garau, and Alexandre Kalache Tags: All Categories Global Health Policy Prevention Primary Care Public Health Source Type: blogs
Please Poke My Paronychium!
THE BASICSWhat is more satisfying than draining a pus-filled paronychium? Seeing the look of relief on the face of your patient when his painful, pulsating digit is relieved of all that tension! This rather elementary procedure could be perceived as stale and uneventful for some of you. The more thorough and astute clinicians, however, realize these tiny infections around the nail root may open the door to a mixed bag of insidious and harmful bacterial infections including MRSA, chronic reoccurrences, cellulitis, subungual abscesses, osteomyelitis, herpetic whitlow, or even the dreaded felon.
Whatever your pleasure, thi...
Source: The Procedural Pause - May 1, 2013 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs
Six ways Big Pharma manipulates consumers - Salon
This article originally appeared on AlterNet.
The blockbuster pill profit party is over for Big Pharma. Bestselling pills like Lipitor, Seroquel, Zyprexa, Singular and Concerta have gone off patent and sites which their ads sustained are withering on the vine. WebMD, for example, the voice of Pharma on the Web, with a former Pfizer exec serving as CEO, announced it would cut 250 positions in December.
But don’t worry, Wall Street. Pharma isn’t going to deliver disappointing earnings just because it has little or no new drugs coming online and has failed at the very reason for its existence. Here are six new Pharma ma...
Source: PharmaGossip - April 28, 2013 Category: Pharma Commentators Authors: insider Source Type: blogs
Will that Toilet Seat Give Me Herpes? Coping with Public Restroom Anxiety
It's totally normal to be afraid of what lurks on public toilet seats, but they're probably not as bad as you think.Contributor: Molly GoldenPublished: Apr 26, 2013 (Source: Most Recent Health Wellness - Associated Content)
Source: Most Recent Health Wellness - Associated Content - April 27, 2013 Category: Other Conditions Source Type: blogs
MKSAP: 19-year-old woman with bilateral leg weakness
Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians.
A 19-year-old woman is admitted to the hospital because of a 2-week history of bilateral leg weakness and numbness accompanied by urinary incontinence that began after a viral gastrointestinal illness of 3 days’ duration. She has no personal or family medical history of note and takes no medication.
On physical examination, temperature is 36.7 °C (98.1 °F), blood pressure is 96/55 mm Hg, and pulse rate is 66/min. Bilateral leg weakness, loss of sensation below the umbilicus, and hyperreflexia in the lower...
Source: Kevin, M.D. - Medical Weblog - April 13, 2013 Category: Family Physicians Tags: Conditions Neurology Source Type: blogs
