Lyme Disease
Pathophysiology of Lyme Disease
Lyme disease is an
1) infection with Borrelia burgdorferi via tick bite
2) previous thinking held tick vector was Ixodes but transmission is now thought by some experts to be possible with additional tick species
3) occurs in stage I and stage II days to weeks after infection and in stage III months to years after infection (usually with preceding latency period
Signs and Symptoms
Stage I
1) characteristic expanding annular rash with central clearing (“bull’s eye or “target” rash) that occurs in only 40% of infections
Stage II
2) multiple secondary annular skin lesio...
Source: Inside Surgery - March 19, 2013 Category: Surgeons Authors: Editor Tags: Infectious Disease babesia bulls eye rash coinfections deer tick erythema migrans hyperbaric ixodes target rash Source Type: blogs
Antimicrobial peptides induced by herpesvirus enhance HIV-1 infection
The risk of being infected with human immunodeficiency virus type 1 (HIV-1) is substantially enhanced in individuals with other sexually transmitted diseases. For example, infection with herpes simplex virus type 2 (HSV-2) increases the risk ratio of acquiring HIV from 2 to 4. Explanations for this increased risk include direct inoculation of HIV-1 into the blood through genital ulcers, and the induction of inflammatory cells by HSV-2 which act as sites of replication for HIV-1. The results of infections carried out in cell culture suggest a biological mechanism for the enhancement of HIV-1 infection by HSV-2.
Langerhans c...
Source: virology blog - February 21, 2013 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Information AIDS antimicrobial peptides CCR5 CD4 CXCR4 genital ulcer disease HIV-1 HSV-2 keratinocyte LL-37 viral virus Source Type: blogs
Top stories in health and medicine, February 15, 2013
This series is brought to you by MedPage Today.1. Repealing SGR Raises Questions for Congress. Opinions on what to replace Medicare’s sustainable growth rate (SGR) formula with and how to get there vary greatly.2. Depression May Lower Response to Shingles Vax. Untreated major depression may hamper the protective effect of varicella zoster virus (VZV) vaccine against herpes zoster — shingles — in older individuals.3. Contraception: Condoms Are King, Plan B Takes Hold. In the realm of contraception, the condom reigns supreme, but one in 10 have used emergency contraception such as Plan B. Manage your online...
Source: Kevin, M.D. - Medical Weblog - February 15, 2013 Category: Family Physicians Tags: News Infectious disease OB/GYN Source Type: blogs
Happy Valentines Day! STI studies and sexual health resources
The studies reveal new infection data, some of it available for the first time, for the eight most common STIs — chlamydia, gonorrhea, syphilis, herpes, human papillomavirus (HPV), hepatitis B, HIV, and trichomoniasis. The studies, which estimate infection rates and medical costs related to STIs, were published in the journal Sexually Transmitted Diseases.
To read an article about the studies: http://nbcnews.to/11Jf4Wr
The CDC has a website where you can learn more about STIs as well as search by zipcode for a clinic that offers STI testing as well as HIV testing the HPV vaccines. To search visit here: http://1.u...
Source: BHIC - February 14, 2013 Category: Databases & Libraries Authors: Monica Rogers Tags: General Health Information Literacy HIV/AIDS Public Health Websites Source Type: blogs
Getting Personal: What It’s Really Like Living With a Sexually Transmitted Infection (STI)
by Jenelle Marie
When you hear the term STD (sexually transmitted disease) or STI (sexually transmitted infection), what do you think of first?
Grotesque pictures of maimed genitalia displayed on a projector during yesteryear’s sex-ed class geared toward frightening you into abstinence? That scene from ” The Hangover” where Sid says, “What happens in Vegas stays in Vegas … except for herpes. That shit will come back with you”?
Whatever first comes to your mind is not likely to include your neighbor, professor, or best friend living with an STI, having an incredible sex life, and otherwise prospering. Th...
Source: Our Bodies Our Blog - February 4, 2013 Category: Health Medicine and Bioethics Commentators Authors: OBOS Tags: Activism & Resources Body Image Sex Education Sexuality STIs Source Type: blogs
Pregnant in Healthcare: diseases to avoid
This article from Nursing Center has some additional information on risks that pregnant healthcare workers are exposed to, with some suggestions for how to mitigate these risks. As a currently pregnant, currently recovering from very mild illness person, I can attest that it's pretty miserable being sick when you don't have many options for medication, are already tired, are at greater risk for dehydration, and are worried about the development of your child.Knowledge is power- hope this list helps you feel more empowered as a pregnant healthcare worker! (Source: Occupational Therapy Notes)
Source: Occupational Therapy Notes - February 1, 2013 Category: Occupational Therapists Tags: practice issues acute care Source Type: blogs
Sarcoma – Signs, Histology, and Treatment
Pathophysiology of Soft Tissue Sarcoma
1) sarcomas of the soft tissue are a family of neoplasms affecting the soft tissue of the body Causes 2) previous radiation 3) HIV 4) genetic predisposition such as L-Fraumeni syndrome 5) asbestosis 6) congenital immunodeficiences 7) dioxin exposure 8) Herpes virus
Signs and Symptoms
1) most common presentation is an enlarging mass 2) pain 3) neuralgia and neurologic deficits, if the tumor encases a nerve structure 4) metastases are usually via the blood system and most commonly go to the lungs
Characteristic Test Findings
Radiology – mass on MRI
Histology/Gross Pathology
1) m...
Source: Inside Surgery - January 27, 2013 Category: Surgeons Authors: Editor Tags: Oncology angiosarcoma leimyosarcoma malignant fibrous histiocytosis p53 Schwannoma tumor suppressor Source Type: blogs
Herpes Simplex
(Source: EverythingHealth)
Source: EverythingHealth - January 26, 2013 Category: Consumer Health News Source Type: blogs
Viruses on Time
Poliovirus recently made the cover of Time magazine. Prompted by a reader question, I searched the Time archive to find out if there have been other virology-themed covers. I found fifteen in all, depicting poliovirus (3), herpesvirus (1), HIV/AIDS (4), influenza (5), and SARS coronavirus (2) (I did not distinguish between US and international editions).
The earliest virus-themed cover that I found has Jonas Salk on the cover of the 29 March 1954 issue. Behind Salk is an image of poliovirus particles, probably drawn from an electron micrograph. Salk’s field trial of inactivated poliovirus vaccine had begun in 1954, a...
Source: virology blog - January 21, 2013 Category: Virology Authors: Vincent Racaniello Tags: Information AIDS H5N1 herpesvirus HIV influenza poliovirus SARS coronavirus Time magazine cover viral virology Source Type: blogs
USMLE Questions – Characteristic Disease Findings
The United States Medical Licensing Examination (USMLE) is designed to emphasize knowledge of clinical scenarios and clinical pearls, even on Step I. Listed below are some commonly encountered disease findings and characteristics.
Feature
Disease
45, X chromosome
Turner’s syndrome
5-HIAA increased in urine
Carcinoid syndrome
Aganglionic rectum
Hirschsrpung’s disease
Apple-core sign on barium enema
Colon cancer
Arched back (opisthotonos)
Tetanus
Argyll-Robertson pupil
Syphilis
Ash leaf on forehead
Tuberous sclerosis
Auer rods
Acute myelogenous leukemia
Austin Flint murmur
Aortic regurgitation...
Source: Inside Surgery - January 18, 2013 Category: Surgeons Authors: Editor Tags: Surgpedia USMLE diseases findings VMA water hammer pulse Source Type: blogs
The 2013 Skinnies Awards: Kim Kardashian gets the Lifetime Achievement Award!
The Skinnies Awards are here at skinema.com! How did Kardashian win this heralded honor? With her psoriasis, herpes, acne, cellulite and more on display, how could she not? See it all now at skinema.com... (Source: Skinema, dermatology in the media blog)
Source: Skinema, dermatology in the media blog - January 7, 2013 Category: Dermatologists Authors: vail reese Tags: Television Source Type: blogs
Transcript of Dr. Bihari Video
00:00 to 02.26—Dr. Bihari gives his background and credentials.
Dr. Bihari: My medical training started at Harvard Medical School. I graduated in 1957. Then I trained in Internal Medicine at one of the Harvard teaching hospitals in Boston, Beth Israel, and then in Neurology at Massachusetts General in Boston. Then I went to the National Institutes of Health for two years doing brain physiology—brain research. I did another residency training in Psychiatry in New York, at Columbia Presbyterian Medical Center and then, over the following five or six years, I got very involved in working in Drug Addiction. By 1974, I was...
Source: HONEST MEDICINE: My Dream for the Future - May 16, 2011 Category: Consumer Health News Authors: JuliaS1573 at aol.com (Julia Schopick) Tags: Anecdotal Treatments HONEST MEDICINE Integrative Medicine Low Dose Naltrexone Obituaries Source Type: blogs
