AZ at it again
AUTH/2793/9/15 - Clinical pharmacist v AstraZenecaCase number:AUTH/2793/9/15Case ref:Clinical pharmacist v AstraZenecaDescription:Identifying patients suitable for Forxiga treatment and failing to provide an accurate response to the PanelNo breach:No breaches Clauses 2 and 7.2Breach:Breaches Clauses 3.2, 7.2 and 9.1. Corrective statement and public reprimand.Appeal:No appealReview:Published in the May 2016 ReviewReceived:10/09/2015Completed:17/03/20162793Case Summary:​​​​A clinical pharmacist complained about an AstraZeneca leavepiece about how to create a clinical system search to identify patients suitable for tr...
Source: PharmaGossip - September 27, 2016 Category: Pharmaceuticals Authors: insider Source Type: blogs

Alltrials Latest
Dear AllTrials supportersYou may have heard that Mark Zuckerberg, the founder of Facebook, and his wife Priscilla Chan have pledged $3 billion to medical research.That ’s great news for patients and medical researchers worldwide – but only if this money is wisely spent. Right now, around $85 billion of medical research is wasted every year in the US alone. That’s far more than just a lot of money down the drain, it means wasted opportunities to find new trea tments and cures. But there are simple things funders like Chan and Zuckerberg can do to make sure that their generous donations result in cures...
Source: PharmaGossip - September 26, 2016 Category: Pharmaceuticals Authors: insider Source Type: blogs

Oh dear ASDA
(function(d, s, id) { var js, fjs = d.getElementsByTagName(s)[0]; if (d.getElementById(id)) return; js = d.createElement(s); js.id = id; js.src = "//connect.facebook.net/en_GB/sdk.js#xfbml=1&version=v2.3"; fjs.parentNode.insertBefore(js, fjs);}(document, 'script', 'facebook-jssdk'));Oh dear Asda......Posted by I Am Proud To Be British on Sunday, 26 October 2014 (Source: PharmaGossip)
Source: PharmaGossip - November 5, 2015 Category: Pharmaceuticals Authors: insider Source Type: blogs

Happy Halloween - there can be only one this year!
(Source: PharmaGossip)
Source: PharmaGossip - October 30, 2015 Category: Pharmaceuticals Authors: insider Source Type: blogs

AllTrials update
Dear friend of AllTrialsOver the past few weeks we've heard some great examples of what AllTrials supporters are doing to get all clinical trials registered and reported. Here’s what some of your fellow campaign supporters have been up to.Consultant Diabetologist Dr Aus Alzaid from Saudi Arabia was interested in the results of a clinical trial investigating the effect of metformin on cognitive function. The trial was completed in 2012 but results have never been published. After writing emails to the researchers and academic institution asking for the missing results, we have now heard they will be publishe...
Source: PharmaGossip - October 4, 2015 Category: Pharmaceuticals Authors: insider Source Type: blogs

Marcia Angell writes
By Marcia AngellIn 1953, a new drug was released by Burroughs Wellcome, a pharmaceutical company based in London. Pyrimethamine, as the compound was named, was originally intended to fight malaria after the microorganisms that cause the disease developed resistance to earlier therapies. The drug was used against malaria for several decades, often in combination with other compounds. It’s mostly used now to treat toxoplasmosis, a parasitic infection that can be life-threatening in people whose immune systems are suppressed, for example, by HIV/​AIDS or cancer.More than 40 years later, Burroughs Wellcome merged with ...
Source: PharmaGossip - October 3, 2015 Category: Pharmaceuticals Authors: insider Source Type: blogs

AllTrials in the USA
We’re excited to announce that 50 patient groups, consumer organisations and medical societies have come together to launch AllTrials USA today! These groups have said:"We are calling on everyone in our sector to join us in supporting the AllTrials campaign. Hundreds of thousands of patients have taken part in clinical trials which have never reported results. For every day that passes, more information is at risk of being lost forever. We have to make every clinical trial count. Join us today."Patient activist AnnaMarie Ciccarella said: “We provided our bodies, our tissue samples, our ...
Source: PharmaGossip - July 28, 2015 Category: Pharmaceuticals Authors: insider Source Type: blogs

Richmond Pharmacology update
Here is a quick note about yesterday's hearing. Judgment is expected next week. The judge grasped the importance of trial registration and when he took into account our and the HRA's evidence on legal and ethical obligations to register trials he found that Richmond was left with an extraordinarily narrow argument. It seems the case will come down to some words in a Q&A on HRA's website that wasn't amended at the same time as the sponsors' declaration was. And then whether the ambiguity was significant.We are so pleased we decided to intervene in the case. The court could find for Richmond on this very narrow...
Source: PharmaGossip - July 19, 2015 Category: Pharmaceuticals Authors: insider Source Type: blogs

Further Update
Hi AllTrials friendsYesterday we sent our submission to the court in the judicial review brought against the HRA by Richmond Pharmacology.We have spent the last few weeks ploughing through the hundreds of pages of documents. Richmond is currently asking the judge to rule that there is no overriding legal requirement to publicly register any trial. That’s not correct. Since 2011 all trials except for adult phase 1 have been publicly registered through the EU Clinical Trials Register. And by next year this legal requirement will extend to all clinical trials unless exempted according to some very tight criteria. Richmo...
Source: PharmaGossip - July 7, 2015 Category: Pharmaceuticals Authors: insider Source Type: blogs

AllTrials vs Richmond Pharmacology
Dear AllTrials friendWe hoped to tell you more about the case Richmond Pharmacology is bringing against the HRA. That's not been straightforward. Richmond has now changed their argument three times and has altogether abandoned some arguments it relied upon earlier, so getting to grips with what is at stake has been difficult and time consuming for us and for our lawyers.At the beginning of this week it looked as though Richmond had narrowed the case down to a technical argument about the wording of HRA’s guidelines which only applied for a period of 10 days earlier this year.Just as the issues seemed to be narrowing,...
Source: PharmaGossip - June 24, 2015 Category: Pharmaceuticals Authors: insider Source Type: blogs

Ben Goldacre writes in the BMJ - How medicine is broken, and how we can fix it
The chief medical officer’s review on statins and oseltamivir may look for answers in the wrong placesLast week there was extensive news coverage of a leaked letter written by the chief medical officer to the Academy of Medical Sciences. This letter focused especially on concerns around statins and oseltamivir (Tamiflu) and asked the academy for an “authoritative independent report looking at how society should judge the safety and efficacy of drugs.”1 The academy has since announced that it is convening a working group on the subject.With any such report there are two major risks. The first is a focus on...
Source: PharmaGossip - June 22, 2015 Category: Pharmaceuticals Authors: insider Source Type: blogs

A message from AllTrials about Richmond Pharmacology's Judicial Review
Dear AllTrials friendAs most of you know Richmond Pharmacology has brought a judicial review against the Health Research Authority because it insists on the registration (not even reporting, but registration) of clinical trials. Read more.This is a quick note to let you know that we have obtained the court papers (hundreds of them!), we are looking urgently with lawyers at what can be done and we will be in touch next week to tell you. In the meantime, if you have been meaning to help with our campaign fund, now would be a great time...  And if you can help with time over July, please tell us by replyin...
Source: PharmaGossip - June 11, 2015 Category: Pharmaceuticals Authors: insider Source Type: blogs

Sidney Wolfe writes in the BMJ - AllTrials - Selective clinical trial reporting: betraying trial participants, harming patients
Reporting biases found in trials of cardiovascular devices Reporting biases in published trials were first identified in 1986. 1  Published randomized studies of combination chemotherapy compared with treatment with an alkylating agent as first line treatment for ovarian cancer showed a significant survival advantage for combination chemotherapy. Unpublished cancer trial registry data from the same studies, however, showed no such advantage. 2  Similarly, in the treatment of multiple myeloma, registry data suggested a smaller survival advantage for combination chemotherapy (over prednisone and an alkyla...
Source: PharmaGossip - June 10, 2015 Category: Pharmaceuticals Authors: insider Source Type: blogs

Sidney Wolfe writes in the BMJ - AllTrials - Selective clinical trial reporting: betraying trial participants, harming patients
Reporting biases found in trials of cardiovascular devicesReporting biases in published trials were first identified in 1986.1 Published randomized studies of combination chemotherapy compared with treatment with an alkylating agent as first line treatment for ovarian cancer showed a significant survival advantage for combination chemotherapy. Unpublished cancer trial registry data from the same studies, however, showed no such advantage.2 Similarly, in the treatment of multiple myeloma, registry data suggested a smaller survival advantage for combination chemotherapy (over prednisone and an alkylating agent) tha...
Source: PharmaGossip - June 10, 2015 Category: Pharmaceuticals Authors: insider Source Type: blogs

Introducing GlobalLeaks
https://globaleaks.org/GlobaLeaks is an open source project aimed at creating a worldwide, anonymous, censorship-resistant, distributed whistleblowing platform. (Source: PharmaGossip)
Source: PharmaGossip - May 25, 2015 Category: Pharmaceuticals Authors: insider Source Type: blogs

AllTrials has changed the world
(Source: PharmaGossip)
Source: PharmaGossip - April 30, 2015 Category: Pharmaceuticals Authors: insider Source Type: blogs

From Evidence-Based Medicine to Marketing-Based Medicine
Dr Peter Parry is an Australian child & adolescent psychiatrist who has researched the "Pediatric Bipolar Disorder" diagnosis emanating from the USA, a diagnosis completely at odds with his training and clinical experience in Australian child and adolescent mental health. As part of his research into the PBD phenomenon, he noticed hundreds of internal pharmaceutical industry documents publicly released from court cases against pharmaceutical firms by State and Federal Attorney Generals in the USA. These documents concurred with findings of the US Senate "Grassley Commission" into conflicts of i...
Source: PharmaGossip - April 30, 2015 Category: Pharmaceuticals Authors: insider Source Type: blogs

Ben Goldacre - Progress and Barriers on Clinical Trials Transparency
(Source: PharmaGossip)
Source: PharmaGossip - April 30, 2015 Category: Pharmaceuticals Authors: insider Source Type: blogs

Psychiatrists With Ties to AstraZeneca Resign From Texas State Hospital
By  ED SILVERMAN Bloomberg NewsTwo psychiatrists at a Texas state hospital have resigned after being told they would face disciplinary actions for accepting hundreds of thousands of dollars in speaking and consulting fees from AstraZeneca AZN +1.58% while also promoting one of its drugs to state officials, according to a spokeswoman for the Texas Department of State Health Services.The psychiatrists allegedly violated various department rules as a result of their relationship to the drug maker, which involved efforts to ensure the Seroquel XR antipsychotic would be placed on the state formular...
Source: PharmaGossip - April 21, 2015 Category: Pharmaceuticals Authors: insider Source Type: blogs

Yes!
WHO calls for increased transparency in medical researchNote for the media14 April 201514 APRIL | 2015 GENEVA - WHO today issued a public statement calling for the disclosure of results from clinical trials for medical products, whatever the result. The move aims to ensure that decisions related to the safety and efficacy of vaccines, drugs and medical devices for use by populations are supported by the best available evidence.“Our intention is to promote the sharing of scientific knowledge in order to advance public health,” said Dr. Marie-Paule Kieny, WHO Assistant Director General for Health Systems and...
Source: PharmaGossip - April 13, 2015 Category: Pharmaceuticals Authors: insider Source Type: blogs

Read it and weep - then get angry!
The Deadly Corruption of Clinical TrialsUpdate (4/3/2015):  After nearly 11 years of obfuscation and denial surrounding the tragic death of Dan Markingson, the University of Minnesota has suspended enrollment in psychiatric drug trials. This comes in response to a blistering report issued by the Minnesota State Legislative Auditor that cites "serious ethical issues" and vindicates much of the reporting in the story below. Read more from Carl Elliott about the fallout from the report here.IT'S NOT EASY TO WORK UP a good feeling about the institution that destroyed your life, which may be why Ma...
Source: PharmaGossip - April 3, 2015 Category: Pharmaceuticals Authors: insider Source Type: blogs

Wine anyone?
(Source: PharmaGossip)
Source: PharmaGossip - March 5, 2015 Category: Pharmaceuticals Authors: insider Source Type: blogs

Tattoo
(Source: PharmaGossip)
Source: PharmaGossip - March 5, 2015 Category: Pharmaceuticals Authors: insider Source Type: blogs

Tales from the PMCPA contd. - The case of the beer drinking, lederhosen wearing, presenter
​A pulmonologist working in Germany, complained about a scientific symposium organised by Boehringer Ingelheim at the European Respiratory Society (ERS) Congress held in Munich.The symposium was part of the industry sponsored sessions.  It was advertised in the official meeting programme as ‘Slowing disease progression in IPF [idiopathic pulmonary fibrosis]: New evidence From Phase III clinical trials’.The complainant stated that his main complaint was that on the main stage, the speakers were allowed to drink beer – with one even dressed in lederhosen.  For a serious, fatal condition, this wa...
Source: PharmaGossip - February 19, 2015 Category: Pharmaceuticals Authors: insider Source Type: blogs

Tax the Rich: An animated fairy tale
(Source: PharmaGossip)
Source: PharmaGossip - February 16, 2015 Category: Pharmaceuticals Authors: insider Source Type: blogs

Last Week Tonight with John Oliver: Marketing to Doctors (HBO)
(Source: PharmaGossip)
Source: PharmaGossip - February 9, 2015 Category: Pharmaceuticals Authors: insider Source Type: blogs

Mother brought to tears hearing Johnson & Johnson's Risperdal tactics
David Sell Posted:   Friday, January 30, 2015, 8:05 AM Benita Pledger dabbed at her tears as she sat in a wooden chair outside a court room in Philadelphia's City Hall early Thursday evening. "I'm just having a hard time right now," she said, "hearing what the pharmaceutical company was doing." Pledger had just finished a full day of listening to her attorney, Thomas Kline, and former U.S. Food and Drug Administration commissioner Dr. David Kessler discuss documents that showed Johnson & amp; Johnson's Janssen Pharmaceutical subsidiary tried to manipulated data in versions of r...
Source: PharmaGossip - January 29, 2015 Category: Pharmaceuticals Authors: insider Source Type: blogs

Mother brought to tears hearing Johnson & Johnson's Risperdal tactics
David SellPosted: Friday, January 30, 2015, 8:05 AMBenita Pledger dabbed at her tears as she sat in a wooden chair outside a court room in Philadelphia's City Hall early Thursday evening."I'm just having a hard time right now," she said, "hearing what the pharmaceutical company was doing."Pledger had just finished a full day of listening to her attorney, Thomas Kline, and former U.S. Food and Drug Administration commissioner Dr. David Kessler discuss documents that showed Johnson & Johnson's Janssen Pharmaceutical subsidiary tried to manipulated data in versions of reports to hide evidence that...
Source: PharmaGossip - January 29, 2015 Category: Pharmaceuticals Authors: insider Source Type: blogs

NNT - The Website
http://www.thennt.com (Source: PharmaGossip)
Source: PharmaGossip - January 28, 2015 Category: Pharmaceuticals Authors: insider Source Type: blogs

A "must read" - Cargo Cult Science by Richard Feynman
From a Caltech commencement address given in 1974 Also in Surely You're Joking, Mr. Feynman!During the Middle Ages there were all kinds of crazy ideas, such as that a piece of of rhinoceros horn would increase potency. Then a method was discovered for separating the ideas--which was to try one to see if it worked, and if it didn't work, to eliminate it. This method became organized, of course, into science. And it developed very well, so that we are now in the scientific age. It is such a scientific age, in fact, that we have difficulty in understanding how witch doctors could ever have existed, when nothing that...
Source: PharmaGossip - September 1, 2014 Category: Pharma Commentators Authors: insider Source Type: blogs

Cancer Drugs Fund receives boost but will no longer fund “overpriced” drugs = BMJ
Cancer Drugs Fund receives boost but will no longer fund “overpriced” drugsBMJ 2014; 349 doi: http://dx.doi.org/10.1136/bmj.g5382 (Published 01 September 2014)Cite this as: BMJ 2014;349:g5382Nigel HawkesThe Cancer Drugs Fund has been given a 40% increase in funding and has agreed to remove from its list any drugs that are overpriced or produce little clinical benefit. The fund’s chairman also promised to try to align the fund’s assessments more closely with those of the National Institute for Health and Care Excellence (NICE).NHS England, which is responsible for the drugs fund, has agreed to increa...
Source: PharmaGossip - September 1, 2014 Category: Pharma Commentators Authors: insider Source Type: blogs

Saturday cartoons
(Source: PharmaGossip)
Source: PharmaGossip - August 30, 2014 Category: Pharma Commentators Authors: insider Source Type: blogs

Novartis fails to report side effects, fatality
6:52 pm, August 30, 2014Jiji PressNovartis Pharma K.K. said it has failed to report to the health ministry at least 2,579 cases of serious side effects, including a fatality, from its drugs for leukemia and other diseases even though its employees were aware of the problems.Of the total, 1,313 cases were related to Glivec and 514 cases to Tasigna, both drugs for leukemia treatment, and 261 cases involved cancer drug Afinitor, said the Japanese unit of Swiss drug giant Novartis AG on Friday.The findings were reported to the Health, Labor and Welfare Ministry the same day.Marketing employees at the firm had recognized the si...
Source: PharmaGossip - August 30, 2014 Category: Pharma Commentators Authors: insider Source Type: blogs

AllTrials: Withholding results costs lives
(Source: PharmaGossip)
Source: PharmaGossip - August 22, 2014 Category: Pharma Commentators Authors: insider Source Type: blogs

AllTrials: Doctors are being misled. Reboxetine
(Source: PharmaGossip)
Source: PharmaGossip - August 22, 2014 Category: Pharma Commentators Authors: insider Source Type: blogs

Dr. John Ioannidis on The Reliability of Biomedical Evidence and H...
(Source: PharmaGossip)
Source: PharmaGossip - August 20, 2014 Category: Pharma Commentators Authors: insider Source Type: blogs

A new blog to follow: Chaos Theory and Human Pharmacology
http://chaoticpharmacology.wordpress.com/ (Source: PharmaGossip)
Source: PharmaGossip - August 17, 2014 Category: Pharma Commentators Authors: insider Source Type: blogs

Illinois Suspends Michael Reinstein's Medical License
Michael Reinstein (Gerald Rich/ProPublica)Illinois medical regulators have indefinitely suspended the medical license of psychiatrist Michael Reinstein, who prescribed more of the most powerful and riskiest antipsychotic drug clozapine than any other doctor in the country.The decision by Illinois' Department of Financial and Professional Regulation, signed Friday, suspends Reinstein's license for a minimum of three years, at which time he can apply to have it reinstated.The state's medical disciplinary board recommended the sanction in May after determining that Reinstein, 71, received "illegal direct and in...
Source: PharmaGossip - August 16, 2014 Category: Pharma Commentators Authors: insider Source Type: blogs

Pharmalot is THE BEST
http://blogs.wsj.com/pharmalot/ (Source: PharmaGossip)
Source: PharmaGossip - August 16, 2014 Category: Pharma Commentators Authors: insider Source Type: blogs

Why might Alltrials be mired at the EMA one wonders?
Here are 40 million reasons. The report Divide & Conquer: A look behind the scenes of the EU pharmaceutical industry lobby is available athttp://www.corporateeurope.org/sites/default/files/28 March 2012 DivideConquer.pdf and athttp://haieurope.org/wp-content/uploads/2012/03/28-March-2012-DivideConquer.pdf (Source: PharmaGossip)
Source: PharmaGossip - August 10, 2014 Category: Pharma Commentators Authors: insider Source Type: blogs

Broken
http://www.bmj.com/content/bmj/347/bmj.f6980.full.pdf (Source: PharmaGossip)
Source: PharmaGossip - July 26, 2014 Category: Pharma Commentators Authors: insider Source Type: blogs

Dr. Frances Oldham Kelsey is 100
Happy 100th birthday to Dr. Frances Oldham Kelsey, the pharmacologist whose bold stance against inadequate drug testing saved countless newborns from the perils of thalidomide, a drug which caused severe birth defects in over 10,000 infants. On her first month on the job at the U.S. Food and Drug Administration in 1960, the Canadian-born scientist resisted pressure from thalidomide's manufacturer to quickly approve the drug, which was already being widely prescribed in Europe as a painkiller for pregnant women. As a result of Dr. Kelsey's insistence on further safety testing, the drug was never approved in the US, saving a...
Source: PharmaGossip - July 25, 2014 Category: Pharma Commentators Authors: insider Source Type: blogs

Poetry Corner - Cancer's a funny thing
J.B.S. Haldane retained his wit even while undergoing cancer treatments — he wrote this poem in a hospital in 1964:I wish I had the voice of HomerTo sing of rectal carcinoma,Which kills a lot more chaps, in fact,Than were bumped off when Troy was sacked.Yet, thanks to modern surgeon’s skills,It can be killed before it killsUpon a scientific basisIn nineteen out of twenty cases.I noticed I was passing blood(Only a few drops, not a flood).So pausing on my homeward wayFrom Tallahassee to BombayI asked a doctor, now my friend,To peer into my hinder end,To prove or to disprove the rumourThat I had a malignant tumour...
Source: PharmaGossip - July 20, 2014 Category: Pharma Commentators Authors: insider Source Type: blogs

GlaxoChinaGate contd. - now GSK admit they had previous form
GlaxoSmithKline China: Company admits to bribery scandal in 2001GlaxoSmithKline (GSK) has admitted that members of its staff were caught bribing Chinese officials back in 2001, according to the Financial Times.The new information has emerged as the pharmaceutical giant faces intense scrutiny from authorities in the UK and US regarding the alleged bribing of doctors and officials to boost drug sales to China. Police in the country have accused GSK of "ordering" the bribes.The FT report suggests that GSK was forced to fire 30 employees back in 2001 after it found staff were taking kick...
Source: PharmaGossip - July 17, 2014 Category: Pharma Commentators Authors: insider Source Type: blogs

AllTrials News - Out of 400 trials on ClinicalTrials.gov, 30% haven’t reported results
A new study found that 118 of 400 clinical trials had not reported results four years later in either a journal or on ClinicalTrials.gov. The researchers randomly selected trials that were registered on ClinicalTrials.gov and listed as completed in 2008. They found that trials were equally likely to report results regardless of whether or not they were funded by industry.This is yet one more study to look at the reporting of clinical trial results. The best available evidence is still that around half of all clinical trials have never been published or reported their results.Dr Christopher Gill, the study&rs...
Source: PharmaGossip - July 16, 2014 Category: Pharma Commentators Authors: insider Source Type: blogs

Big Pharma pushes the Snake Oil approach
FDA has free-speech, safety issues to weigh in review of ‘off-label’ drug marketing rulesShould a pharmaceutical sales rep be allowed to tell a doctor that Topamax, a drug approved to treat seizures and prevent migraine headaches, might also help combat alcohol dependence? Or suggest the epilepsy drug Neurontin could also help treat bipolar disorders or insomnia? Or offer data showing that any number of other drugs could have uses beyond those listed on their labels?For decades, the answer overwhelmingly has been no. The Justice Department has aggressively pursued companies that run afoul of rule...
Source: PharmaGossip - July 10, 2014 Category: Pharma Commentators Authors: insider Source Type: blogs

Servier distort competition
BRUSSELS — The European Union's antitrust body is imposing a fine of 428 million euros ($580 million) on France's pharmaceutical company Servier and five producers of generic medicines for distorting competition.The 28-nation bloc's executive Commission on Wednesday said Servier struck a series of deals with the producers of generic medicines to protect its bestselling blood pressure medicine, Perindopril, from price competition.EU competition chief Joaquin Almunia says Servier's practices of "systematically buying out any competitive threats" to protect its market was "clearly anti-competitive and abu...
Source: PharmaGossip - July 9, 2014 Category: Pharma Commentators Authors: insider Source Type: blogs

What is called "guolaosi" in Chinese and "karoshi" in Japanese?
Answer: http://arbroath.blogspot.it/2014/07/chinese-man-praised-as-being-example-to.html (Source: PharmaGossip)
Source: PharmaGossip - July 8, 2014 Category: Pharma Commentators Authors: insider Source Type: blogs

Advocate Groups Reach Out to President's Science Advisors Ahead of Antibiotics Meeting | Food Safety News
The President’s Council of Advisors on Science and Technology (PCAST) will meet Friday to discuss its work on antibiotic resistance and nanotechnology and to hear from speakers about oceans policy.A group of public health, consumer, and environmental protection organizations have sent a letter to PCAST expressing concern that the U.S. Food and Drug Administration’s Guidance for Industry #213 and a proposed Veterinary Feed Directive (VFD) rule do not go far enough in addressing antibiotic overuse on farms.By March, FDA had heard from 25 of the 26 drug manufacturers affected by Guida...
Source: PharmaGossip - July 8, 2014 Category: Pharma Commentators Authors: insider Source Type: blogs

Larry Husten writes
Merck Uses Legal Threats To Stifle Negative Advice About Zetia And Vytorin In ItalyIn response to repeated legal threats, a public health doctor in Italy has withdrawn advice to curtail use of a controversial drug. The drug, ezetimibe, is a key ingredient in Zetia and Vytorin, which is manufactured by Merck . The cholesterol-lowering drug has been the subject of fierce controversy because it has never been shown to improve clinical outcomes. Despite the controversy, in 2013 the drugs had combined sales of more than $2.6 billion.MSD Italy, the Italian arm of the company, sent two “cease and desist&rdquo...
Source: PharmaGossip - July 7, 2014 Category: Pharma Commentators Authors: insider Source Type: blogs