Independence in Content Moderation
John SamplesSocial media managers cannot tolerate all speech on their platforms. They are obligated to maximize value for their shareholders. Leaving some kinds of speech on a platform would drive some users away. So social media managers establish rules intended to maximize the number of users. Managers also hire content moderators to enforce the rules. Users that get thrown off have no complaint. When they joined the platform, they agreed to the rules and to how they are enforced. End of story.Except it ’s not the end of the story. Social media managers do not seem to believe that mutual consent to rules and their appl...
Source: Cato-at-liberty - September 8, 2020 Category: American Health Authors: John Samples Source Type: blogs
The Republican Party ’s Confusion on Trade
David BoazThere ’s been a lot oftalk this week about what today ’s Republican Partystands for. Is it still the Buckley ‐Reagan fusionist platform of of lower taxes, less regulation, traditional values, and a strong national defense? Is it George W. Bush ’s “compassionate conservatism”? Trump’s “America First,” which always seemed less ideological than most platforms? The talk heated up when the GOP announced that it wouldn ’t produce a party platform for the first time in memory, and the Republican National Committeeunanimously voted in lieu of a platform its “undivided sup...
Source: Cato-at-liberty - August 28, 2020 Category: American Health Authors: David Boaz Source Type: blogs
A Two Part Interview with Greg Bailey of Juvenescence
Juvenescence and Life Biosciences are presently the two large business development companies in the growing longevity industry. They act much like venture funds, in that they create or take controlling positions in biotech startups, but are organized as companies in structure, with the ability to later go public. The resulting entity looks much like a Big Pharma company with many subsidiaries. It is quite possible to do this at a smaller scale and bootstrap towards much the same end goal - see Ichor Therapeutics and its portfolio companies, for example.
Greg Bailey is one of the cofounders of Juvenescence, alongside...
Source: Fight Aging! - August 25, 2020 Category: Research Authors: Reason Tags: Investment Source Type: blogs
Update: The latest research and noninvasive neurotechnologies for brain health and mental fitness
Time for a new edition of SharpBrains’ e‑newsletter!
1. Food for (nonpartisan) Thought: Should heads of state and candidates to high office pass a cognitive/ mental fitness test?
2. A school psychologist shares good tips to support our kids and, yes, manage our own stress. Three Ss to reduce the stress of “homeschooling” our kids: Simplify, Structure, Support.
3. Wow. Mindstrong Health raises $100M to transform how we measure and promote mental health.
4. Great partnership! Kaiser Permanente offers Calm mental fitness app at no cost to millions of members.
5. “Just as you can’t self-introspect to determine...
Source: SharpBrains - May 29, 2020 Category: Neuroscience Authors: SharpBrains Tags: Cognitive Neuroscience Education & Lifelong Learning Health & Wellness Technology app brain health Brain Teasers brain-teaser Calm cognitive test FDA Headsafe Kaiser-Permanente Kernel mental health mental-fitness Mindstrong Source Type: blogs
Brain Teaser: How to choose the right shirt size
You have been invited to a fundraising gala at your old college (via Zoom of course) and decide that this black-tie event demands a super white Italian shirt, like the one you bought years ago for your wedding.
When you find and bravely try the wedding shirt on (size 16), your wife notices that the collar suffocates you — you DO need about 1/4″ more space everywhere in-between your neck and the collar all around your neck.
So you’ll need a new shirt.
What size shirt do you need to buy?
PS1: In case you don’t know, shirt size 16 means that a tape wrapped around your neck and two fingers positioned flat upfront...
Source: SharpBrains - May 22, 2020 Category: Neuroscience Authors: Maria Lando Tags: Brain Teasers Education & Lifelong Learning brain puzzles for adults brain-teaser-games cognitive-skills Source Type: blogs
Brain Teaser: What shirt size you need?
You have been invited to a fundraising gala at your old college (via Zoom of course) and decide that this black-tie event demands a super white Italian shirt, like the one you bought years ago for your wedding.
When you find and bravely try the wedding shirt on (size 16), your wife notices that the collar suffocates you — you DO need about 1/4″ more space everywhere in-between your neck and the collar all around your neck.
So you’ll need a new shirt.
What size shirt do you need to buy?
PS1: In case you don’t know, shirt size 16 means that a tape wrapped around your neck and two fingers positioned flat upfront...
Source: SharpBrains - May 22, 2020 Category: Neuroscience Authors: Maria Lando Tags: Brain Teasers Education & Lifelong Learning brain puzzles for adults brain-teaser-games cognitive-skills Source Type: blogs
Podcast: Deconstructing Mental Health Month
It’s Mental Health Awareness Month! But what does that mean, exactly? Who are we raising awareness for? Is “mental health” the same as “mental illness?” In this Not Crazy Podcast, Gabe and Lisa ponder the meaning of this decades-old campaign and discuss the pros and cons of the movement.
What do you think? Is Mental Health Awareness Month a necessary outreach that sheds light on mental health, or is it a flimsy substitute for actual help? Tune in for an in-depth discussion that entails several different perspectives.
(Transcript Available Below)
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Source: World of Psychology - May 19, 2020 Category: Psychiatry & Psychology Authors: Not Crazy Podcast Tags: General Mental Health and Wellness Not Crazy Podcast Policy and Advocacy Source Type: blogs
The Moonshot Venture Fellowship at Apollo Ventures
One of the more productive strategies undertaken by advocates and venture firms in the longevity industry is to put effort into the creation of companies, rather than waiting for companies to arise. This is still a small, young industry, without the sizable ecosystem that attends more mature areas of biotechnology, and thus many, many lines of research that might be productively developed into therapies targeting the mechanisms of aging remain stuck in academia. For investors and advocates to change this state of affairs requires building connections in the research community, introducing researchers and entrepreneurs, and...
Source: Fight Aging! - May 19, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Happy 90th Birthday, Ed Clark
David BoazEd Clark, the 1980 Libertarian Party presidential nominee, turns 90 years old on May 4. Now that Rep. Justin Amash has thrown his hat into the ring for the 2020 nomination, I thought I’d offer some reminiscences about the earlier campaign.In my misguided youth I was a teenage Young Democrat, a College Republican, and a young adult Libertarian Party activist, before I gave up politics for ideas and policy. In 1978, a few years out of college, I left my conservative job to become co‐manager of Ed Clark’s campaign for Governor of California on t he Libertarian ticket. (He was actually on the ball...
Source: Cato-at-liberty - May 1, 2020 Category: American Health Authors: David Boaz Source Type: blogs
Health in 2 Point 00, Episode 116 | Telehealth $$, Layoffs and Rock Health ’ s Q1 fundraising report
Today on Health in 2 Point 00, Jess and I run through a lot of telehealth investments including Doctor Anywhere raising $27 million, 98point6 raising $43 million, Tyto Care raising $50 million, SilverCloud Health raising $16 million, SteadyMD raising $6 million, and Aktiia raising $6 million. In addition, there’s a company called Air Doctor which matches people when they’re traveling to doctors on the ground which raised $7.8 million despite the inauspicious timing. On the flip side, there have been a slew of layoffs in the space, and Jess and I give our $.02 on Rock Health’s Q1 fundraising report which w...
Source: The Health Care Blog - April 10, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Health in 2 Point 00 Health Tech Health Technology Jessica DaMassa Matthew Holt Start-Ups 98point6 Air Doctor Aktiia Doctor Anywhere Glen Tullman Livongo Rock Health SilverCloud Health SteadyMD Telehealth Tyto Ca Source Type: blogs
Fight Aging! Newsletter, March 30th 2020
This study, for the first time, shows that transplantation of non-autologous mitochondria from healthy skeletal muscle cells into normal cardiomyocytes leads to short-term improvement of bioenergetics indicating "supercharged" state. However, over time these improved effects disappear, which suggests transplantation of mitochondria may have a potential application in settings where there is an acute stress.
Outlining Some of the Science Behind Partial Reprogramming at Turn.bio
https://www.fightaging.org/archives/2020/03/outlining-some-of-the-science-behind-partial-reprogramming-at-turn-bio/
Turn.bio is ...
Source: Fight Aging! - March 29, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Ronjon Nag on Investment in the Longevity Industry
Ronjon Nag is a noted angel investor in the Bay Area, and one of the newer entries to the select community of investors interested in the longevity industry. He brings his own perspective to the table; new points of view are always welcome as the community grows in size, and as more narrowly focused specialists begin to emerge. That said, given the enormous venture funding still in waiting, looking for places to invest, there is always the perverse incentive for fund managers to consider the space of aging and longevity in the broadest sense possible. There is a pressure to invest now, invest soon, find more deals to parti...
Source: Fight Aging! - March 23, 2020 Category: Research Authors: Reason Tags: Investment Source Type: blogs
The End of an Era
John SamplesNo, not the end of the Trump Era. Or the Obama Era. Or an “era” named after a politician, including the Reagan Era. Or even the end of the New Deal, or the Great Society, or whatever.It ’s actually the end of the era of campaign finance “reform,” born in 1969 died in 2020. Many people helped end this era, among them Barack Obama (whose fundraising prowess destroyed the presidential public finance program) and Donald Trump (who showed that you could capture a major party ’s nomination without spending “big money.”) But it was Michael Bloomberg that actually ended the era.A political era...
Source: Cato-at-liberty - March 23, 2020 Category: American Health Authors: John Samples Source Type: blogs
Fight Aging! Newsletter, March 16th 2020
We report a new class of natural-product-inspired covalent inhibitors of telomerase that target the catalytic active site.
Age-Related Epigenetic Changes that Suppress Mitochondrial Function
https://www.fightaging.org/archives/2020/03/age-related-epigenetic-changes-that-suppress-mitochondrial-function/
Today's open access research reports on two specific epigenetic changes observed in old individuals that act to reduce mitochondrial function. This joins an existing list of genes for which expression changes are known to impact mitochondrial function with age. A herd of hundreds of mitochondria are found...
Source: Fight Aging! - March 15, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Views on Investment in the Longevity Industry
Today I'll point out a couple of short interviews on the topic of investment in the longevity industry. This industry is young and still quite small, taking its present shape over the last five years or so. There are a little more than a hundred companies in the industry, a dozen venture funds that make significant numbers of investments, and - as of yet - no approved drugs emerged from phase III trials. Most programs are still at a preclinical stage of development. From the archly conservative perspective of Big Pharma and the largest established biotech venture funds, this whole endeavor remains an experiment in its earl...
Source: Fight Aging! - March 12, 2020 Category: Research Authors: Reason Tags: Investment Source Type: blogs
