The Biggest Trend You ’ve Probably Never Heard Of: A Status Report on 138 Healthcare ICOs
Discussion and Commentary  The first observation we’ll note is that there has been a substantial amount of healthcare ICO activity. However, we would label the overall performance of the healthcare ICOs as “disappointing”. Only 5 reported positive returns since the date of their listing and 2 in 2018 to-date. The overall ICO market has been declining since January 2018. Monthly funds raised by ICOs are down, and funding has shifted towards a few mega projects (like EOS and Telegram), big private sales, and smart contract platforms. During the bull market of 2017, healthcare ICOs greatly benefited from burgeoning pri...
Source: The Health Care Blog - September 24, 2018 Category: Consumer Health News Authors: matthew holt Tags: Cryptocurrency Economics Finance decentralization Funding Healthcare ICO initial coin offering network effects Startup token token offering venture capital Source Type: blogs

SENS Research Foundation Scientists Plan their First Mouse Studies for Allotopic Expression of Mitochondrial Genes
I notice that the lead researcher on the MitoSENS program at the SENS Research Foundation recently gave an interview at Longecity. This work is focused on the prevention of the mitochondrial contribution to degenerative aging, and has been underway for some years. A separate update at the Life Extension Advocacy Foundation, where a crowdfunding event for MitoSENS was organized back in 2015, notes that progress in this work has continued quietly since the last big announcement, and a transition from cell studies to the first mouse studies for that team lies ahead. Mitochondria are the power plants of the cell, the de...
Source: Fight Aging! - September 21, 2018 Category: Research Authors: Reason Tags: Healthy Life Extension Community Source Type: blogs

Ethics and Society Newsfeed – September 21, 2018
Politics Trump Rated Worse Than Other Modern-Day Presidents on Ethics “The American public’s ratings of the ethical standards of Trump and his administration’s top officials are generally much worse than their ratings of his predecessors. Trump is viewed as having lower ethical standards than all presidents since Nixon, who resigned when faced with imminent impeachment.” […] (Source: blog.bioethics.net)
Source: blog.bioethics.net - September 21, 2018 Category: Medical Ethics Authors: Ethics and Society Tags: Health Care Politics Reproductive Ethics Technology artificial intelligence assisted reproduction bioethics business ethics Catholic church Contemporary Ethical Issues Dark Money disaster ethics Donald Trump fundraising In the Source Type: blogs

Methuselah Fund Closes Initial Fundraising, Reports on Some Early Investments
I'm pleased to note that the Methuselah Fund has closed its first fundraising effort after hitting the target amount, obtaining the support of many long-standing members of our community. The fund is a mixed for-profit/non-profit vehicle that is intended to expand the investment efforts undertaken by the Methuselah Foundation in past years, helping promising lines of rejuvenation research to make the leap from laboratory to commercial development. At the present point in time there are few enough rejuvenation focused companies that doing this well requires extensive connections within the research community, and a willingn...
Source: Fight Aging! - September 18, 2018 Category: Research Authors: Reason Tags: Activism, Advocacy and Education Source Type: blogs

September is National Service Dog Month
Originally known as National Guide Dog Month, " National Service Dog Month " was first established in 2008 by actor and animal activist, Dick Van Patten. Inspired by what was a life-changing visit toThe Guide Dogs of the Desert in California, Van Patten launched a fundraising drive to benefit guide and service dog training schools throughout the country  - and create an awareness month for the campaign.Service dogs provide companionship, inspire confidence, and live to serve, protect, and assist their handlers. There are different kinds of trained animals, including guide dogs, emotional ...
Source: Dr. Deborah Serani - September 17, 2018 Category: Psychiatry & Psychology Tags: awareness campaigns service animals. Source Type: blogs

Fight Aging! Newsletter, September 17th 2018
In this study, we found that TXNIP deficiency induces accelerated senescent phenotypes of mouse embryonic fibroblast (MEF) cells under high glucose condition and that the induction of cellular ROS or AKT activation is critical for cellular senescence. Our results also revealed that TXNIP inhibits AKT activity by a direct interaction, which is upregulated by high glucose and H2O2 treatment. In addition, TXNIP knockout mice exhibited an increase in glucose uptake and aging-associated phenotypes including a decrease in energy metabolism and induction of cellular senescence and aging-associated gene expression. We propose that...
Source: Fight Aging! - September 16, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, September 3rd 2018
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - September 2, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, August 27th 2018
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - August 26, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, August 20th 2018
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - August 19, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, August 6th 2018
In this study, we analyzed FGF21 levels and alterations in the expression of genes encoding components of the FGF21-responsive molecular machinery in adipose tissue from aged individuals so as to ascertain whether altered FGF21 responsiveness that develops with aging jeopardizes human health and/or accelerates metabolic disturbances associated with aging. We studied a cohort of 28 healthy elderly individuals (≥70 years) with no overt signs of metabolic or other pathologies and compared them with a cohort of 35 young healthy controls (≤40 years). Serum FGF21 levels were significantly increased in elderly individ...
Source: Fight Aging! - August 5, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

If Nobody Remembers Us
Here's my latest story, which published inGatherDC:Ann stood alone on the other side of the dance floor, swaying offbeat. I approached my friend in her white gown. She looked as chic as my tailored tux and bow tie, which someone else knotted for me because I suck at “adulting”. The closer I got to her, the more I thought Ann looked inebriated and like she wasn’t there at all. I also thought we looked better than the rest of our C-squad royalty status at the Grand Finale Gala for the Leukemia& Lymphoma Society Man& Woman of the Year campaign. We were celebrating a fundraising campaign that raised $2.4 million ...
Source: cancerslayerblog - July 26, 2018 Category: Cancer & Oncology Tags: death Source Type: blogs

Liz Parrish and BioViva, a Chapter in the Telomerase Gene Therapy Book
As a part of efforts to push forward the treatment of aging as a medical condition, Liz Parrish underwent telomerase and follistatin gene therapies a few years ago. She formed a company, BioViva Sciences, to follow through. Self-experimentation is the most ethical of all possible ways proceed from animal studies to human studies, and is unfairly slandered in this day and age. There is a long history of notable researchers first testing their work on themselves. Self-experimentation must be followed through by success in business, fundraising, research and development, however - the areas in which all too many initiatives...
Source: Fight Aging! - July 23, 2018 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Fight Aging! Newsletter, July 23rd 2018
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - July 22, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs