Fight Aging! Newsletter, September 28th 2020
In conclusion, it remains unclear if brain-specific regional and temporal changes occur in the expression of the different APP variants during AD progression. Since APP is also found in blood cells, assessing the changes in APP mRNA expression in peripheral blood cells from AD patients has been considering an alternative. However, again the quantification of APP mRNA in peripheral blood cells has generated controversial results. Brain APP protein has been analyzed in only a few studies, probably as it is difficult to interpret the complex pattern of APP variants and fragments. We previously characterized the soluabl...
Source: Fight Aging! - September 27, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Rescuing Senescent Cells by Delivering New Mitochondria Sounds Like a Risky Proposition
Mitochondria are effectively power plants, hundreds of these organelles per cell working to create the chemical energy store molecule adenosine triphosphate. Mitochondria are the descendants of ancient symbiotic bacteria, and retain many bacterial characteristics, including a small genome, the mitochondrial DNA, and the ability to replicate. Mitochondrial dysfunction is one of the paths by which cells can become senescent, entering a state of growth arrest while secreting an inflammatory set of signals, but mitochondria are in any case involved in the transition to senescence in response to other forms of damage or dysfunc...
Source: Fight Aging! - September 24, 2020 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Getting the best treatment for your fibromyalgia
Imagine being in pain and having your doctor tell you it’s all in your head. Unfortunately, this is not an uncommon experience for many of the six million Americans living with fibromyalgia, a chronic, painful condition. People with fibromyalgia experience widespread pain, aches, and stiffness in muscles and joints throughout the body, as well as unusual tiredness. No one knows what causes this condition, and no apparent physical cause has been identified thus far. The most likely culprit is a brain malfunction that amplifies normal nerve responses, causing people with fibromyalgia to experience pain or other symptoms wh...
Source: Harvard Health Blog - September 10, 2020 Category: Consumer Health News Authors: Kelly Bilodeau Tags: Bones and joints Fatigue Health Pain Management Source Type: blogs

Post Covid Healthcare is Becoming Like Buying from Amazon Instead of Going to the Mall or Reading an eBook Instead of a Paperback
By HANS DUVEFELT, MD Now that we are seeing patients via telemedicine or even getting reimbursed for handling their issues over the phone, our existing healthcare institutions are more and more starting to look like shopping malls.  They were once traffic magnets, so large that they created new developments far away from where people lived or worked and big and complex enough that going there became an all day affair for many people.  What this pandemic has brought us is a shift in our view of where you have to be in order to get things done. If you can earn your wage remotely and still buy things online...
Source: The Health Care Blog - August 5, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Medical Practice Source Type: blogs

Why your bowels are making you sick
The intestinal microbiome plays a huge role in how you feel, your mental outlook, how well you sleep, as well as your health. It can be responsible for health conditions such as irritable bowel syndrome, fibromyalgia, restless leg syndrome, type 2 diabetes, pre-diabetes, hypertension, fatty liver, autoimmune and neurodegenerative conditions. It has become easier to identify, then manage, your intestinal microbiome and you don’t even need a doctor to do it. The post Why your bowels are making you sick appeared first on Dr. William Davis. (Source: Wheat Belly Blog)
Source: Wheat Belly Blog - June 20, 2020 Category: Cardiology Authors: Dr. Davis Tags: Open bowel flora microbiota prebiotic probiotic undoctored wheat belly Source Type: blogs

5 Things I Learned from Lock-down
As New Zealand emerges from the most severe lock-down levels to greater freedom (but still not back to life as usual) I’ve been reflecting on what I’ve learned – no, not a new language, new baking skills, or sudden competence in using R (see here for a great tutorial), but things about myself. Odd though it may seem, I’m leaving lock-down with a sense of wistfulness. You see, the time from the end of March to end of April has been a lovely time for me. I’m lucky, I have a good job, my work hasn’t changed much (well, a bit), my family are safe, I live close to the beach and a park, an...
Source: HealthSkills Weblog - May 17, 2020 Category: Anesthesiology Authors: BronnieLennoxThompson Tags: Pain conditions Professional topics Resilience/Health Uncategorized COVID19 Source Type: blogs

Trial By Error: Today is May 12th and Everyone ’ s Missing
By David Tuller, DrPH Today, May 12th, is International Awareness Day for Chronic Immunological and Neurological Diseases (CIND)—often shortened to International ME (or ME/CFS) and Fibromyalgia Awareness Day. Besides ME, other diseases included in the CIND group, per the May 12th International Awareness Day site, are chronic fatigue syndrome, Gulf War Syndrome and multiple chemical […] (Source: virology blog)
Source: virology blog - May 12, 2020 Category: Virology Authors: David Tuller Tags: Uncategorized Source Type: blogs

What you need to know about fibromyalgia
Fibromyalgia can be an incapacitating condition for many people with diffuse aches and pains that generally do not respond well to drugs. Prescription drugs for this condition are also plagued by substantial side-effects, as well as costs. There are a handful of natural strategies that have yielded extravagant successes for many people, lessons learned from the worldwide Wheat Belly and Undoctored programs. The post What you need to know about fibromyalgia appeared first on Dr. William Davis. (Source: Wheat Belly Blog)
Source: Wheat Belly Blog - May 9, 2020 Category: Cardiology Authors: Dr. Davis Tags: Open fibromyalgia Lyrica microbiota pain meds prebiotic prednisone probiotic sibo small intestinal bacterial overgrowth undoctored wheat belly Source Type: blogs

Will the Covid-Induced Telemedicine Scramble Change Primary Care Forever?
By HANS DUVEFELT, MD After my posts on telemedicine were published recently, (this one on Manly Wellness before the pandemic and this one after it erupted, on A Country Doctor Writes, then reblogged on The Health Care Blog, KevinMD and many others), I have been asked about my views on telemedicine’s role in the future of primary care. Things have changed quickly, and a bit chaotically, and there is a lot of experimentation happening right now in practices I work or speak with. Before thinking about telemedicine in Primary Care, we need to agree on some sort of definition of primary care, because ...
Source: The Health Care Blog - April 27, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Medical Practice primary care Telehealth Telemedicine Source Type: blogs

Caregiver Living With Chronic Pain Must Set LImits on Care
Photo credit Kat  Dear Carol: My 80-year-old mother had a stroke two years ago and lives in a close-by nursing home. I’m happy to visit her and make sure that her needs are met, but that’s not enough for her. She says it’s my duty to take her to the mall and other places to shop. She’s a large woman and taking her out in this way means getting her in and out of the car as well as wrestling a wheelchair in and out of my car trunk. I have fibromyalgia and body-wide arthritis, but she’s never accepted my health challenges. I’ve offered to take her for drives since the nursing home staff will help her in and ...
Source: Minding Our Elders - April 24, 2020 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs

On labels and boundaries
What we call a disease matters. It matters to the person because a diagnosis is a marker: this problem is known, it’s recognised, it’s real (Mengshoel, Sim, Ahlsen & Madden, 2017). It matters to the clinician, particularly medical practitioners, but also those clinicians working within a largely “disease-oriented” framework (for example, physiotherapists, osteopaths) (Haskins, Osmotherly, Rivett, 2015; Kennedy, 2017). It matters also to insurance companies, or funding providers – who is in, and who is out. The diagnostic label itself hides a great many assumptions. The ways in which dia...
Source: HealthSkills Weblog - April 6, 2020 Category: Anesthesiology Authors: BronnieLennoxThompson Tags: Assessment Chronic pain Clinical reasoning Coping strategies Pain conditions Professional topics Uncategorized Source Type: blogs

Part One: Tapping the Wrist
​The wrist is not commonly aspirated in the emergency department, but emergent arthrocentesis may be indicated for extreme or concerning cases, and tapping the wrist to determine the underlying pathology or relieve pain may be of great value. The synovial fluid from the joint space can be analyzed for crystals, infection, and blood. This information may help determine the overall plan and aid in decision-making and consultation. The ultimate treatment plan may include admission, intravenous antibiotics, multiple aspirations, and even surgical washout.A swollen, painful wrist that is hot to the touch is concerning for sep...
Source: The Procedural Pause - April 1, 2020 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs

Podcast: Coronavirus – How to Keep it Together
  How are you handling the coronavirus pandemic? Most people are struggling right now, but for those of us with mental illness, these days can feel truly overwhelming. Fear, depression, isolation and loss of routine are just a few of the difficulties many of us are facing. In today’s podcast, Gabe and Jackie discuss what we can do right now to make things just a little better, and they share their personal hopes and fears for humanity once this pandemic subsides. You’re not alone — we’re all in this together. Join us for an important discussion on how we can handle this time of fear and uncertainty. (T...
Source: World of Psychology - March 23, 2020 Category: Psychiatry & Psychology Authors: Not Crazy Podcast Tags: Anxiety and Panic General LifeHelper Mental Health and Wellness Not Crazy Podcast Source Type: blogs

Some unconventional thoughts on coronavirus (COVID-19)
Public health authorities are advising frequent hand washing and social distancing, especially in the absence of confirmatory testing for COVID-19. I don’t have any wisdom to add to these practices. Vaccines are in the works, as are anti-viral drugs—nothing to add here, either. But let me reiterate what we do in the Wheat Belly and Undoctored lifestyles. In general, we do not treat diseases; we correct the factors that allow disease to emerge in the first place—a big difference. Take rheumatoid arthritis, for example. In conventional healthcare, the joint pain and swelling of rheumatoid arthritis are sup...
Source: Wheat Belly Blog - March 18, 2020 Category: Cardiology Authors: Dr. Davis Tags: Open probiotic undoctored wheat belly Source Type: blogs

Caregiver with Chronic Pain Must Be Clear About Limits
Photo credit Kat-J Dear Carol: My 80-year-old mother had a stroke two years ago and lives in a close-by nursing home. I’m happy to visit her and make sure that her needs are met, but that’s not enough for her. She says it’s my duty to take her to the mall and other places to shop. She’s a large woman and taking her out in this way means getting her in and out of the car as well as wrestling a wheelchair in and out of my car trunk. I have fibromyalgia and body-wide arthritis, but she’s never accepted my health challenges.  I’ve offered to take her for drives since the nursing home staff will help her in an...
Source: Minding Our Elders - January 25, 2020 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs