Contact Dermatitis to Titanium Cochlear Implants: A Case Series
Dermatitis. 2024 Apr 23. doi: 10.1089/derm.2023.0424. Online ahead of print.NO ABSTRACTPMID:38656131 | DOI:10.1089/derm.2023.0424 (Source: Dermatitis)
Source: Dermatitis - April 24, 2024 Category: Dermatology Authors: Meghan R Mansour Kathleen Dass Source Type: research
Filaggrin Mutation Status and Prevention of Atopic Dermatitis with Maternal Probiotic Supplementation
Acta Derm Venereol. 2024 Apr 24;104:adv24360. doi: 10.2340/actadv.v104.24360.ABSTRACTThe World Allergy Organization recommends probiotics in the prevention of atopic dermatitis in high-risk populations. Mutations in the filaggrin gene (FLG) result in an increased risk of atopic dermatitis through disruption of the skin keratin layer. This exploratory study investigated whether the preventive effect of maternal probiotics was evident in children with and without FLG mutations. DNA was collected from children (n = 228) from the Probiotic in the Prevention of Allergy among Children in Trondheim (ProPACT) study. Samples were a...
Source: Acta Dermato-Venereologica - April 24, 2024 Category: Dermatology Authors: Dinastry Pramadita Zakiudin Jacob P Thyssen Claus Zachariae Vibeke Videm Torbj ørn Øien Melanie Rae Simpson Source Type: research
Interleukin antagonists for atopic dermatitis: a new era of therapy
Expert Opin Investig Drugs. 2024 Apr 24. doi: 10.1080/13543784.2024.2347294. Online ahead of print.ABSTRACTINTRODUCTION: Over the last decade, increasing understanding of the immunopathogenesis of atopic dermatitis (AD) enabled the recognition of multiple therapeutic targets and subsequently the development of novel, highly effective systemic treatments, including interleukin (IL)-antagonists. To date, the IL-4Ra-inhibitor dupilumab, and the IL-13 inhibitor tralokinumab, have gained regulatory approval in Europe for the treatment of moderate-to-severe AD, while more than 70 new therapeutics are currently in development.ARE...
Source: Expert Opinion on Investigational Drugs - April 24, 2024 Category: Drugs & Pharmacology Authors: Aikaterini Tsiogka Eleni Paschou Dimitra Koumaki Efstratios Vakirlis Stamatios Gregoriou Source Type: research
Filaggrin Mutation Status and Prevention of Atopic Dermatitis with Maternal Probiotic Supplementation
Acta Derm Venereol. 2024 Apr 24;104:adv24360. doi: 10.2340/actadv.v104.24360.ABSTRACTThe World Allergy Organization recommends probiotics in the prevention of atopic dermatitis in high-risk populations. Mutations in the filaggrin gene (FLG) result in an increased risk of atopic dermatitis through disruption of the skin keratin layer. This exploratory study investigated whether the preventive effect of maternal probiotics was evident in children with and without FLG mutations. DNA was collected from children (n = 228) from the Probiotic in the Prevention of Allergy among Children in Trondheim (ProPACT) study. Samples were a...
Source: Acta Derm Venereol A... - April 24, 2024 Category: Dermatology Authors: Dinastry Pramadita Zakiudin Jacob P Thyssen Claus Zachariae Vibeke Videm Torbj ørn Øien Melanie Rae Simpson Source Type: research
Response to "Cetrimonium Bromide Patch Test Positivity Is Found With a High Frequency in a Cohort of Patients With Frontal Fibrosing Alopecia"
Dermatitis. 2024 Apr 24. doi: 10.1089/derm.2024.0046. Online ahead of print.NO ABSTRACTPMID:38656914 | DOI:10.1089/derm.2024.0046 (Source: Dermatitis)
Source: Dermatitis - April 24, 2024 Category: Dermatology Authors: Michelle Sikora Ambika Nohria Deesha Desai Maryanne M Senna Avrom S Caplan Jerry Shapiro Kristen Lo Sicco Source Type: research
Solvent Orange 60 in Tortoiseshell Spectacle Frames: The Importance of Patch Testing to This Rare Allergen
Dermatitis. 2024 Apr 24. doi: 10.1089/derm.2023.0404. Online ahead of print.NO ABSTRACTPMID:38656913 | DOI:10.1089/derm.2023.0404 (Source: Dermatitis)
Source: Dermatitis - April 24, 2024 Category: Dermatology Authors: Caroline Brumley Puneet Arora John F Elliott Solveig Ophaug Source Type: research
Contact Dermatitis to Titanium Cochlear Implants: A Case Series
Dermatitis. 2024 Apr 23. doi: 10.1089/derm.2023.0424. Online ahead of print.NO ABSTRACTPMID:38656131 | DOI:10.1089/derm.2023.0424 (Source: Dermatitis)
Source: Dermatitis - April 24, 2024 Category: Dermatology Authors: Meghan R Mansour Kathleen Dass Source Type: research
Filaggrin Mutation Status and Prevention of Atopic Dermatitis with Maternal Probiotic Supplementation
Acta Derm Venereol. 2024 Apr 24;104:adv24360. doi: 10.2340/actadv.v104.24360.ABSTRACTThe World Allergy Organization recommends probiotics in the prevention of atopic dermatitis in high-risk populations. Mutations in the filaggrin gene (FLG) result in an increased risk of atopic dermatitis through disruption of the skin keratin layer. This exploratory study investigated whether the preventive effect of maternal probiotics was evident in children with and without FLG mutations. DNA was collected from children (n = 228) from the Probiotic in the Prevention of Allergy among Children in Trondheim (ProPACT) study. Samples were a...
Source: Acta Dermato-Venereologica - April 24, 2024 Category: Dermatology Authors: Dinastry Pramadita Zakiudin Jacob P Thyssen Claus Zachariae Vibeke Videm Torbj ørn Øien Melanie Rae Simpson Source Type: research
Filaggrin Mutation Status and Prevention of Atopic Dermatitis with Maternal Probiotic Supplementation
Acta Derm Venereol. 2024 Apr 24;104:adv24360. doi: 10.2340/actadv.v104.24360.ABSTRACTThe World Allergy Organization recommends probiotics in the prevention of atopic dermatitis in high-risk populations. Mutations in the filaggrin gene (FLG) result in an increased risk of atopic dermatitis through disruption of the skin keratin layer. This exploratory study investigated whether the preventive effect of maternal probiotics was evident in children with and without FLG mutations. DNA was collected from children (n = 228) from the Probiotic in the Prevention of Allergy among Children in Trondheim (ProPACT) study. Samples were a...
Source: Acta Dermato-Venereologica - April 24, 2024 Category: Dermatology Authors: Dinastry Pramadita Zakiudin Jacob P Thyssen Claus Zachariae Vibeke Videm Torbj ørn Øien Melanie Rae Simpson Source Type: research
Filaggrin Mutation Status and Prevention of Atopic Dermatitis with Maternal Probiotic Supplementation
Acta Derm Venereol. 2024 Apr 24;104:adv24360. doi: 10.2340/actadv.v104.24360.ABSTRACTThe World Allergy Organization recommends probiotics in the prevention of atopic dermatitis in high-risk populations. Mutations in the filaggrin gene (FLG) result in an increased risk of atopic dermatitis through disruption of the skin keratin layer. This exploratory study investigated whether the preventive effect of maternal probiotics was evident in children with and without FLG mutations. DNA was collected from children (n = 228) from the Probiotic in the Prevention of Allergy among Children in Trondheim (ProPACT) study. Samples were a...
Source: Acta Derm Venereol A... - April 24, 2024 Category: Dermatology Authors: Dinastry Pramadita Zakiudin Jacob P Thyssen Claus Zachariae Vibeke Videm Torbj ørn Øien Melanie Rae Simpson Source Type: research
Filaggrin Mutation Status and Prevention of Atopic Dermatitis with Maternal Probiotic Supplementation
Acta Derm Venereol. 2024 Apr 24;104:adv24360. doi: 10.2340/actadv.v104.24360.ABSTRACTThe World Allergy Organization recommends probiotics in the prevention of atopic dermatitis in high-risk populations. Mutations in the filaggrin gene (FLG) result in an increased risk of atopic dermatitis through disruption of the skin keratin layer. This exploratory study investigated whether the preventive effect of maternal probiotics was evident in children with and without FLG mutations. DNA was collected from children (n = 228) from the Probiotic in the Prevention of Allergy among Children in Trondheim (ProPACT) study. Samples were a...
Source: Acta Derm Venereol A... - April 24, 2024 Category: Dermatology Authors: Dinastry Pramadita Zakiudin Jacob P Thyssen Claus Zachariae Vibeke Videm Torbj ørn Øien Melanie Rae Simpson Source Type: research
Filaggrin Mutation Status and Prevention of Atopic Dermatitis with Maternal Probiotic Supplementation
Acta Derm Venereol. 2024 Apr 24;104:adv24360. doi: 10.2340/actadv.v104.24360.ABSTRACTThe World Allergy Organization recommends probiotics in the prevention of atopic dermatitis in high-risk populations. Mutations in the filaggrin gene (FLG) result in an increased risk of atopic dermatitis through disruption of the skin keratin layer. This exploratory study investigated whether the preventive effect of maternal probiotics was evident in children with and without FLG mutations. DNA was collected from children (n = 228) from the Probiotic in the Prevention of Allergy among Children in Trondheim (ProPACT) study. Samples were a...
Source: Acta Dermato-Venereologica - April 24, 2024 Category: Dermatology Authors: Dinastry Pramadita Zakiudin Jacob P Thyssen Claus Zachariae Vibeke Videm Torbj ørn Øien Melanie Rae Simpson Source Type: research
Antibiotics within first year are linked to infant gut microbiome disruption and elevated atopic dermatitis risk
(Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - April 24, 2024 Category: Allergy & Immunology Authors: Courtney Hoskinson, Maria V. Medeleanu, Myrtha E. Reyna, Darlene LY. Dai, Biswajit Chowdhury, Theo J. Moraes, Piushkumar J. Mandhane, Elinor Simons, Anita L. Kozyrskyj, Meghan B. Azad, Charisse Petersen, Stuart E. Turvey, Padmaja Subbarao Source Type: research
Biologic and Small Molecule Therapy for Treating Moderate to Severe Atopic Dermatitis: Mechanistic Considerations
Atopic dermatitis (AD) is a complex and heterogeneous skin disease where achieving complete clinical clearance for most patients has proven challenging through single cytokine inhibition. Current studies integrate biomarkers and evaluate their role in AD, aiming to advance our understanding of the diverse molecular profiles implicated. While traditionally characterized as a Th2-driven disease, extensive research has recently revealed the involvement of Th1, Th17, and Th22 immune pathways, as well as the interplay of pivotal immune molecules, such as OX40, OX40 ligand (OX40L), thymic stromal lymphopoietin (TSLP), and IL-33....
Source: Journal of Allergy and Clinical Immunology - April 24, 2024 Category: Allergy & Immunology Authors: Camille Rothenberg-Lausell, Jonathan Bar, Dante Dahabreh, Yael Renert-Yuval, Ester del Duca, Emma Guttman-Yassky Source Type: research
Immunologic Profiling of Immune-Related Cutaneous Adverse Events with Checkpoint Inhibitors Reveals Polarized Actionable Pathways
CONCLUSIONS: Distinct immunologic ircAE endotypes suggest actionable targets for precision medicine-based interventions.PMID:38652814 | DOI:10.1158/1078-0432.CCR-23-3431 (Source: Clinical Cancer Research)
Source: Clinical Cancer Research - April 23, 2024 Category: Cancer & Oncology Authors: Mario E Lacouture Elena Goleva Neil Shah Veronica Rotemberg Lukas Kraehenbuehl Kwami F Ketosugbo Taha Merghoub Tara Maier Alexander Bang Stephanie Gu Trina Salvador Andrea P Moy Taras Lyubchenko Olivia Xiao Clifton F Hall Evgeny Berdyshev James Crooks Rya Source Type: research
