Can AI and radiographs help in resource-poor areas for the fight against COVID-19?
Conclusion  With new evidence emerging every day and with COVID-19 guidance and protocols adapting responsively, the national responses vary widely across the globe. However, Singapore, Taiwan and South Korea have shown that aggressive and proactive testing plays a crucial role in containing the spread of the disease.  We believe AI has great potential for helping doctors quantify and monitor COVID progression from a patient’s chest X-rays – this will help determine treatment pathways faster and thus slow any surges in emergency cases. AI will also play a critical role in expanding screening for...
Source: The Health Care Blog - May 7, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Health Tech bhargava reddy manoj tld pooja rao preetham srinivas qure.ai tarun raj Source Type: blogs

The Top 5 Practical Digital Health Technologies in the Fight Against COVID-19: An Infographic
We reported on how digital health came to the spotlight early on. As we learn more about the disease, we see digital health technologies increasingly getting adopted in this context. We created an infographic to summarize all the digital health tech efforts against this pandemic.  This will help caregivers and policymakers understand how we can rely on technologies in the fight against the novel coronavirus; and which sectors and phases of healthcare are aided by digital health. In our infographic, listed on the Y-axis are the technologies making a significant impact in the fight against the pandemic. Indicated ...
Source: The Medical Futurist - May 7, 2020 Category: Information Technology Authors: Prans Tags: Future of Medicine Telemedicine & Smartphones Virtual Reality digital health infographics covid covid19 Source Type: blogs

Rapamycin Slows Age-Related Periodontitis in Mice
The mTOR inhibitor rapamycin slows the progression of aging in mice. The may largely be a result of upregulated autophagy, as is the case for many other means of slowing aging in short-lived species, including calorie restriction. If an intervention slows aging generally, the odds are fairly good that any specific aspect of aging will also be slowed. Here, researchers show that rapamycin treatment improves the outlook for age-related periodontitis in mice. Periodontal disease, also known as gum disease, is a common problem in older adults that causes painful inflammation, bone loss, and changes in the good bacteri...
Source: Fight Aging! - May 6, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Fight Aging! Newsletter, May 4th 2020
The objective is to start treating chronic diseases from the root and not the symptoms of the disease. As we are starting to enroll patients in "senolytics-clinical trials," it will be imperative to assess if senolysis efficiently targets the primary cause of disease or if it works best in combination with other drugs. Additional basic science research is required to address the fundamental role of senescent cells, especially in the established contexts of disease. Notes on Self-Experimentation with Sex Steroid Ablation for Regrowth of the Thymus https://www.fightaging.org/archives/2020/04/notes-on-self-experi...
Source: Fight Aging! - May 3, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Pain from an Unknown Cause
​"My left hip has been hurting for a couple years, but it just got really bad in the past few weeks."My patient, who was in her 70s, didn't add much more to the history. No trauma. No fevers. No bowel or bladder problems. No significant past medical history. Her hip just hurt. She thought she needed an x-ray, and one was obtained.The left femoral head didn't look terrible. There was some irregularity, but there were no fractures or significant joint narrowing. This wasn't a case of neglected severe degenerative joint disease or avascular necrosis that needed a hip replacement.Some red flags started to show up t...
Source: Lions and Tigers and Bears - May 1, 2020 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs

Notes on Self-Experimentation with Sex Steroid Ablation for Regrowth of the Thymus
I periodically publish thoughts on self-experiments that seem interesting and relevant to aging. Despite the influence of the quantified self movement, the broader self-experimentation community is largely terrible on matters of research, rigor, reporting, and safety. My motivation is to something to raise the bar on all of these items. For every discussion I've published on a particular self-experiment, there are half a dozen others sitting at some stage of research and interest. Over the past year or so, I've been on and off looking into sex steroid ablation as a mechanism for thymus regrowth. Since my company, Re...
Source: Fight Aging! - April 30, 2020 Category: Research Authors: Reason Tags: Self-Experimentation Source Type: blogs

New radiation therapies keep advanced prostate cancer in check
Treatments for prostate cancer are always evolving, and now research is pointing to new ways of treating a cancer that has just begun to spread, or metastasize, after initial surgery or radiation. Doctors usually give hormonal therapies in these cases to block testosterone, which is a hormone that makes the cancer grow faster. But newer evidence shows that treating the metastatic tumors directly with radiation can produce better results. In March, researchers published the latest study that supports this approach. Based at Johns Hopkins University School of Medicine in Baltimore, the team used a method for delivering power...
Source: Harvard Health Blog - April 28, 2020 Category: Consumer Health News Authors: Charlie Schmidt Tags: Living With Prostate Cancer Prostate Knowledge Treatments HPK Source Type: blogs

Can Artificial Intelligence effectively and ethically detect COVID-19?
Is Artificial Intelligence (AI) a viable solution to the COVID-19 testing crisis? This has been a major question buzzing in the minds of healthcare leaders as they scramble to come up with solutions to the short-supply of the conventional tests. Some researchers believe that it ’s possible to develop a specialized method to detect specific markers of the virus via AI. However, COVID-19-detecting algorithms are based on data from only dozens or hundreds of patients, whereas a fully effective and functional algorithm requires thousands of patient scans. Recently written algorithms were developed using scans of infected C...
Source: radRounds - April 19, 2020 Category: Radiology Authors: Julie Morse Source Type: blogs

Fight Aging! Newsletter, April 20th 2020
In conclusion, elevated brain amyloid was associated with family history and APOE ε4 allele but not with multiple other previously reported risk factors for AD. Elevated amyloid was associated with lower test performance results and increased reports of subtle recent declines in daily cognitive function. These results support the hypothesis that elevated amyloid represents an early stage in the Alzheimer's continuum. Blood Metabolites as a Marker of Frailty https://www.fightaging.org/archives/2020/04/blood-metabolites-as-a-marker-of-frailty/ Frailty in older people is usually diagnosed in a symptomatic...
Source: Fight Aging! - April 19, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

The (Sober) State of Artificial Intelligence in the Fight Against COVID-19
If you ask us at The Medical Futurist about the importance of artificial intelligence in healthcare, we will have a lot to talk about. We’ve seen how it could solve alarm fatigue in hospitals. We’ve analyzed the unusual associations the technology discovered in medicine. We believe it will usher the real era of the Art of Medicine. Dr. Meskó even embarked on a journey to better understand the language of A.I. So of course, with the COVID-19 pandemic, we had to explore the contribution of A.I. in this public health crisis. We came across promising endeavours involving such algorithms from mining for insights through...
Source: The Medical Futurist - April 14, 2020 Category: Information Technology Authors: Prans Tags: Artificial Intelligence Future of Medicine digital health coronavirus covid covid19 Source Type: blogs

Many People Aged 40 to 50 Exhibit Rapid Progression of Preclinical Atherosclerosis
This study is the first to analyze the progression of atherosclerosis at frequent intervals. The previous view was that the disease progressed very slowly throughout life. However, the new results show that the disease progressed very rapidly in 40% of the individuals analyzed. Future data from the PESA study will show whether this progression is associated with subsequent cardiovascular events. Until now, the speed of atherosclerosis progression has not been a factor in assessing individual risk." "The key finding of the study is that over a short follow-up of just 3 years, 40% of individuals aged between 40 and 5...
Source: Fight Aging! - April 13, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Investigation to assess myocardial metabolism – MCQ
Investigation to assess myocardial metabolism – MCQ Investigation used to assess myocardial metabolism: a) Computed tomography (CT) b) Magnetic resonance imaging (MRI) c) Positron emission tomography (PET) d) Single photon emission tomography (SPECT) Post your answer as a comment below (Source: Cardiophile MD)
Source: Cardiophile MD - April 1, 2020 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Medicine MCQ - CVS Source Type: blogs

Calcium scoring – MCQ – Answer
Calcium scoring – MCQ – Answer Calcium scoring is used as a screening test for – Correct answer: a) Coronary artery disease Though pericardial calcification can be made out by computed tomography (CT), CT is not used for screening pericardial disease as it is rare. Pericardial calcification is seen constrictive pericarditis. Similarly, calcification of aortic valve is associated with cardiac conduction system disease. Still CT is not used as a screening test as ECG is a much cheaper and easily available test for assessment of cardiac conduction system disease. Back to question (Source: Cardiophile MD)
Source: Cardiophile MD - April 1, 2020 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Medicine MCQ - CVS Source Type: blogs

False Negative: Testing ’s Catch-22
By SAURABH JHA, MD In a physician WhatsApp group, a doctor posted he had fever of 101° F and muscle ache, gently confessing that it felt like his typical “man flu” which heals with rest and scotch. Nevertheless, he worried that he had coronavirus. When the reverse transcription polymerase chain reaction (RT-PCR) for the virus on his nasal swab came back negative, he jubilantly announced his relief.  Like Twitter, in WhatsApp emotions quickly outstrip facts. After he received a flurry of cheerful emojis, I ruined the party, advising that despite the negative test he assume he’s infected and quarantine for ...
Source: The Health Care Blog - March 29, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Health Policy RogueRad @roguerad coronavirus coronavirus testing COVID-19 testing false negatives novel coronavirus Pandemic RT-PCR Saurabh Jha Source Type: blogs

Infection Control for COVID-19 Imaging
Discussion: A fear in pandemics is the overwhelming of hospital system capacity by the infected.  As a single confirmed COVID patient can take down a CT or MR suite for anywhere between 1 and 3 hours, depending on whether they are ventilated, this is a reasonable concern. The rate-limiting step in minimizing downtime and enhancing throughput will be air exchange. The following common-sense suggestions may be helpful: First and foremost, PCR is the test of choice for COVID diagnosis. ‘R/O COVID’ using CT is not encouraged. Second, a lot of information can be obtained by a portable chest x-ray. Portable che...
Source: The Health Care Blog - March 26, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Hospitals Medical Practice Physicians coronavirus CT scans Imaging infecton control Pandemic Radiology Stephen Borstelmann Source Type: blogs