Fight Aging! Newsletter, September 19th 2022
Conclusion Use of the Khavinson peptides and melatonin in combination in this way, at this dose, negatively impacts the thymus, producing a reduction in active tissue and increase in atrophy to fatty tissue. The degree to which this atrophy occurred is greater than one would expect to take place over nine months of aging at this stage of life. Why did this outcome occur, given the animal studies showing thymic regrowth, and the studies showing reduced later life mortality following use of thymogen? We can only speculate. Firstly, the dose makes the poison, and the dosing here may have been too high, too frequ...
Source: Fight Aging! - September 18, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Evidence for Hypertension to Lead to Earlier Onset of Osteoporosis
Researchers here provide evidence for the raised blood pressure of hypertension to accelerate the progression of osteoporosis, the loss of bone density characteristic of old age, leading to an earlier onset of the condition. They speculate that inflammation is the mechanism of interest, based on the differences in outcome following induced hypertension in old mice, already suffering the inflammation of aging, versus induced hypertension in young mice. There are already many good reasons to work to minimize both chronic inflammation and any increase in blood pressure with age; more evidence for just how bad these aspects of...
Source: Fight Aging! - September 14, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Chest pain, peak troponin 100,000 ng/L and this ECG on discharge: what ’s the diagnosis?
Written by Jesse McLaren, with edits by Smith Usually cases are presented in chronological order the way they appear in real life. But this case will be represented in reverse chronological order. At each step we ’ll ask the question, “what’s the diagnosis?” using the STEMI paradigm (was this STEMI or NSTEMI?) and OMI paradigm (was this Occlusion MI or Non-Occlusion MI?).  Discharge A 60 year old without prior cardiac history was admitted with chest pain, had a peak troponin of 100,000 ng/L (normal<16 in female and<26 in males), and was discharged with the following ECG (#4). What ’s the...
Source: Dr. Smith's ECG Blog - September 13, 2022 Category: Cardiology Authors: Jesse McLaren Source Type: blogs

Reporting on a Study of One with Khavinson Peptides and Melatonin for Thymic Regrowth
Conclusion Use of the Khavinson peptides and melatonin in combination in this way, at this dose, negatively impacts the thymus, producing a reduction in active tissue and increase in atrophy to fatty tissue. The degree to which this atrophy occurred is greater than one would expect to take place over nine months of aging at this stage of life. Why did this outcome occur, given the animal studies showing thymic regrowth, and the studies showing reduced later life mortality following use of thymogen? We can only speculate. Firstly, the dose makes the poison, and the dosing here may have been too high, too frequ...
Source: Fight Aging! - September 12, 2022 Category: Research Authors: Reason Tags: Self-Experimentation Source Type: blogs

Gerbode ventricular septal defects type I, II and III
Though congenital left ventricle to right atrium connections have been described as early as 1838 at autopsy [1, cited in 2], the description by Frank Gerbode and colleagues was in 1958, in their surgical series [3]. They described three varieties of communications: Fusion of the septal leaflet of the tricuspid valve to the edges of the ventricular septal defect associated with a perforation of the leaflet. Shunt occurs from left ventricle directly into right atrium. A defect or cleft of tricuspid valve close to its point of attachment directly overlying the VSD. A combination of these two lesions. They also described t...
Source: Cardiophile MD - September 8, 2022 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

Cardiac tumours
Cardiac tumours are most often secondaries from malignancies of breast, lung or malignant melanoma. Primary tumours of the heart are most often benign, of which about half are myxomas. Malignant primary tumours of the heart contribute to about a quarter of the primary cardiac tumours. The commonest primary malignant tumour of the heart would be a sarcoma [1]. Cardiac tumours may present with cardiovascular or constitutional symptoms. Sometimes they are incidentally detected on echocardiography or other imaging modalities. Left atrial myxoma on echocardiogram Computed tomography and magnetic resonance imaging can give addi...
Source: Cardiophile MD - August 25, 2022 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

Heart Health Innovator Cleerly Closes Series C Funding Round with $223 Million
Cleerly, the company creating a new standard of care for heart disease, announced that it has closed a Series C financing round of $223 million. This new funding brings the total raised by the fast-growing health care company to $279 million, which includes its Series B round in 2021. “At Cleerly, we are passionate about our mission to create a new standard of care for heart disease,” said James Min, MD, FACC, FESC, MSCCT, CEO and founder of Cleerly. “We are grateful for this round of financing that will further enable our work and believe it provides a resounding vote of confidence in our vision for the future of ca...
Source: EMR and HIPAA - August 11, 2022 Category: Information Technology Authors: Healthcare IT News Tags: AI/Machine Learning Health IT Company Healthcare IT Cardiovascular Care Cardiovascular Disease Cleerly Computed Tomography CT Fidelity Health IT Funding Health IT Fundings Health IT Investment James Min T. Rowe Price Source Type: blogs

How to Mitigate Ethical Challenges of AI-Driven Healthcare
The following is a guest article by Natalie C. Oehlers, Associate Attorney and Carly C. Koza, Healthcare Associate Attorney at Buchanan Ingersoll & Rooney. While various legislation has been implemented or proposed at both the federal and state levels to standardize and accelerate the development of artificial intelligence (AI), most stop short of addressing the significant ethical challenges that may arise. Now, more than ever, it is important for developers, manufacturers, and healthcare providers to remain vigilant as it relates to ethics surrounding AI.   How AI Improves the Healthcare Industry  AI is a powerful...
Source: EMR and HIPAA - August 9, 2022 Category: Information Technology Authors: Guest Author Tags: AI/Machine Learning Analytics/Big Data Clinical Healthcare IT Hospital - Health System Artificial Intelligence Carly C. Koza ethics Healthcare AI Healthcare AI Ethics Informed Consent Natalie C. Oehlers Source Type: blogs

A man in his 40s with multitrauma from motor vehicle collision
DiscussionThis is a case where clinical context is of vital importance, because the EKG manifestations of cardiac contusion are fairly unpredictable. Intramyocardial hemorrhage, edema, and necrosis of myocardial muscle cells are characteristics of cardiac contusion. All of these cause troponin elevation, making troponin a very specific marker for cardiac injury. It is suggested that a troponin that is within normal reference range at about 4-6 hours from the inciting event suggests strongly the absence of cardiac injury in blunt chest trauma (Sybrandy).The EKG is not generally sensitive for cardiac contusion. The right ven...
Source: Dr. Smith's ECG Blog - August 6, 2022 Category: Cardiology Authors: Pendell Source Type: blogs

Where Will the Healthcare Facility of the Future Look Like?
As we look into the future, we’re seeing how what was needed in the past isn’t what the healthcare facility of the future is going to need.  This was the topic of discussion in our recent podcast and we asked the Healthcare IT Today community what they thought the healthcare facility of the future would look like.  Today we’ll share a number of responses about the facility itself and tomorrow we’ll share a look at the technology that will be needed in the healthcare facility of the future. Richard Watson, MD and Co-founder at Motient There will be greater delineation between general, specialty, an...
Source: EMR and HIPAA - July 28, 2022 Category: Information Technology Authors: John Lynn Tags: Healthcare IT AssureCare Christine DiNoia eVisit Healthcare at Home Healthcare Building Healthcare Facilities Healthcare Facility Healthcare Interoperability Healthcare VR Home Healthcare Lightbeam Health Solutions Marco Pinto Ma Source Type: blogs

L5 Compression Fracture
Starting some weeks back, I was experiencing lower back pain.   It wasn’t getting better. It was getting worse!  I report anything out of the ordinary to the research team (I’m in a phase I clinical trial), and had been doing so with regard to this ailment. Since the pain was only getting worse over time, … (Source: beth's myeloma blog)
Source: beth's myeloma blog - July 25, 2022 Category: Cancer & Oncology Authors: Beth Tags: Myeloma CT Scan fluoroscopy fracture PET Scan Spinal Compression Fracture Source Type: blogs

A woman in her 40s with intractable nausea and vomiting, dyspnea, and lightheadedness
 Submitted and written by Oriane Longerstaey MD, peer reviewed by Meyers, Smith, and McLarenA woman in her 40s with diabetes and HLD presented with nausea and vomiting x3 days. She was seen on day 1 of symptoms at an outside ED, no ECG performed, and sent home with return precautions and zofran, which she had been taking around the clock for persistent nausea and vomiting. She presented on day 3 of symptoms because of new onset dyspnea, tachycardia, lightheadedness, and heart palpitations. She had a " burning " sensation in her chest but no " pain " .A 12 lead EKG was obtained at triage: - Sinus rhythm at 96 bpm&...
Source: Dr. Smith's ECG Blog - July 21, 2022 Category: Cardiology Authors: Pendell Source Type: blogs

Bonus Features – July 3, 3022 – Judge says Apple infringed AliveCor ’ s patent, more than half of patients have trouble managing their records, and more
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job. News An International Trade Commission (ITC) judge has ruled that Apple infringed AliveCor’s patented personal electrocardiogram technology. The judge’s decision follows two complaints that AliveCor filed against App...
Source: EMR and HIPAA - July 3, 2022 Category: Information Technology Authors: Brian Eastwood Tags: C-Suite Leadership Health IT Company Healthcare IT Hospital - Health System AliveCor Andy Powell Apple Autonomous Revenue Cycle Management Cedar Gate Technologies DarioHealth DrFirst ECG Patents Harmony Health IT Healthcare IT To Source Type: blogs

The CT contrast shortage is a learning opportunity
There is currently a pandemic-related shortage of iodinated contrast used for CT scans, predicted to last for several months. While the industry is addressing its own lessons on the supply side of production and distribution, those of us in clinical medicine may use this shortage as an educational opportunity to address contrast demand. There areRead more …The CT contrast shortage is a learning opportunity originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - June 3, 2022 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/post-author/cullen-ruff" rel="tag" data-wpel-link="internal" > Cullen Ruff, MD < /a > < /span > Tags: Conditions Radiology Source Type: blogs

Looking Back At Today ’s Healthcare In 2060
I receive many questions after my talks and on my online channels about the not yet visible future. People want to know what healthcare will be like in the next decades. But throwing around predictions will not help us design a better healthcare. Although showing a utopian future of healthcare might do so. On a chilly October afternoon in 2060, after having watched the leaves falling off the trees in our garden for too long to get bored, my beautiful and overtly curious grandchild, Nina, came to me and started asking me questions. She pointed at one of the many CubeSensors in the living room – small,...
Source: The Medical Futurist - April 26, 2022 Category: Information Technology Authors: berci.mesko Tags: Healthcare Design Science Fiction future Medical education Medicine Personalized medicine technology gc4 Source Type: blogs