Corona second wave might bring some good news !
This article never intends to undermine the importance of preventive measures and vaccine for this worst pandemic in recent human history
(Source: Dr.S.Venkatesan MD)
Source: Dr.S.Venkatesan MD - November 17, 2020 Category: Cardiology Authors: dr s venkatesan Tags: Uncategorized corona second third wave corona second wave corona vaccine what is the case fatality rate in corona Source Type: blogs
Acute Aortic syndrome : Please mind the Length of “ Ascending Aorta ” as well !
Aorta probably is the most critical structure in the entire circulatory system. (apart from the heart of course !) It is a 1.5 to 2.5 mm thick tube, with a diameter of 2.5 cm/length of 30 -35 cm from the aortic valve to the iliac bifurcation.(Eric Borsero 2011) It handles about 7500 liters of blood every day. Understanding the Aortic pathology has vastly improved at the molecular level with deep gene sequencing that defines fibrillin phenotypes. Meanwhile, CT , 4D MRI and 3D prototyping have landed us in a new era where we can feel the exact models of a patient’s virtual aAorta for monitoring and treatment purp...
Source: Dr.S.Venkatesan MD - November 1, 2020 Category: Cardiology Authors: dr s venkatesan Tags: Uncategorized marfan aortic dissection aorta size new coconcepts in aortic dimension normal aorta size normal aortic root size what is normal length of ascending aorta Source Type: blogs
Acute Aortic syndrome : Please mind the length of “ Ascending Aorta ” as well.
Aorta probably is the most critical structure in the entire circulatory system. (apart from the heart of course !) It is a 1.5 to 2.5 mm thick tube, with a diameter of 2.5 cm/length of 30 -35 cm from the aortic valve to the iliac bifurcation.(Eric Borsero 2011) It handles about 7500 liters of blood every day. Understanding the Aortic pathology has vastly improved at the molecular level with deep gene sequencing that defines fibrillin phenotypes. Meanwhile, CT , 4D MRI and 3D prototyping have landed us in a new era where we can feel the exact models of a patient’s virtual aAorta for monitoring and treatment purp...
Source: Dr.S.Venkatesan MD - November 1, 2020 Category: Cardiology Authors: dr s venkatesan Tags: aortic aneurysm marfan aortic dissection aorta size new coconcepts in aortic dimension normal aorta size normal aortic root size what is normal length of ascending aorta Source Type: blogs
Fight Aging! Newsletter, November 2nd 2020
In conclusion, the circulating antibody repertoire has increased binding to thousands of peptides in older donors, which can be represented as an immune age. Increased immune age is associated with autoimmune disease, acute inflammatory disease severity, and may be a broadly relevant biomarker of immune function in health, disease, and therapeutic intervention. The immune age has the potential for wide-spread use in clinical and consumer settings.
In Vivo Reprogramming Improves Cognitive Function in Old Mice
https://www.fightaging.org/archives/2020/10/in-vivo-reprogramming-improves-cognitive-function-in-old-mi...
Source: Fight Aging! - November 1, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Towards a More Sensitive Blood Test for the Earlier Stages of Alzheimer's Disease
The onset of Alzheimer's disease is preceded by years of slowly growing levels of amyloid-β aggregates in the brain. There is an equilibrium between amyloid-β in the brain and amyloid-β in the bloodstream, and so the research community has worked towards blood tests that can determine who is at risk of developing the condition. This goal is complicated by the sensitivity required, given the low levels of amyloid-β in blood samples, but the results here suggest that this problem may be sufficiently well solved to proceed towards an widely used assay. While the failure of clinical trials testing amyloid-clearing immunoth...
Source: Fight Aging! - October 28, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
FlowSense Monitors Hydrocephalus Shunts: Exlusive with Anna Lisa Somera, CEO of Rhaeos
Hydrocephalus patients have an excess of cerebrospinal fluid in the brain, which needs to be drained away through a ventricular shunt. However, these shunts regularly fail, with potentially life-threatening results. At present, there isn’t an easy way to check that a shunt is still working, and clinicians typically use brain MRI/CT scans to see if a shunt is still draining correctly.
Not only are these imaging procedures inconvenient and expensive, but in the case of CT they may expose a hydrocephalus patient to significant amounts of radiation if regular assessments are required. To address this, Rhaeos, a company ba...
Source: Medgadget - October 13, 2020 Category: Medical Devices Authors: Conn Hastings Tags: Exclusive Materials Medicine Neurology Neurosurgery Source Type: blogs
Fight Aging! Newsletter, September 28th 2020
In conclusion, it remains unclear if brain-specific regional and temporal changes occur in the expression of the different APP variants during AD progression. Since APP is also found in blood cells, assessing the changes in APP mRNA expression in peripheral blood cells from AD patients has been considering an alternative. However, again the quantification of APP mRNA in peripheral blood cells has generated controversial results.
Brain APP protein has been analyzed in only a few studies, probably as it is difficult to interpret the complex pattern of APP variants and fragments. We previously characterized the soluabl...
Source: Fight Aging! - September 27, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Philips Azurion Lung Edition for High Precision Bronchoscopy Procedures
Philips has just unveiled its Azurion Lung Edition system that combines a number of technologies that improve how minimally invasive procedures in the lungs are performed. The system relies on Cone Beam CT imaging, to provide a high resolution 3D view of the lungs, along with X-ray guidance for clear awareness of the anatomy being worked on and the tools within. A combination of additional hardware and software features work together to help with thoracoscopic surgeries, biopsies, and lesion ablations that are common when diagnosing and treating lung cancer. Using the Azurion Lung Edition it is possible to complete endobro...
Source: Medgadget - September 22, 2020 Category: Medical Devices Authors: Medgadget Editors Tags: Oncology Radiology Thoracic Surgery Source Type: blogs
Reducing Chronic Inflammation as Effective as Reducing Blood Cholesterol in Producing a Small Reversal of Atherosclerotic Lesions
This study provides characterization of a lipid-rich necrotic core, a dangerous type of coronary plaque made up of dead cells and cell debris that is prone to rupture. Ruptured plaque can lead to a heart attack or stroke.
The analysis involved 209 middle-aged patients (ages 37-62) with psoriasis who participated in the Psoriasis Atherosclerosis Cardiometabolic Initiative at the National Institutes of Health, an ongoing observational study. Of these participants, 124 received biologic therapy, and 85 were in the control group, treated only with topical creams and light therapy. To measure the effects of biologic ther...
Source: Fight Aging! - September 22, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
The Medical AI Floodgates Open, at a Cost of $1000 per Patient
By LUKE OAKDEN-RAYNER
In surprising news this week, CMS (the Centres for Medicare & Medicaid Services) in the USA approved the first reimbursement for AI augmented medical care. Viz.ai have a deep learning model which identifies signs of stroke on brain CT and automatically contacts the neurointerventionalist, bypassing the first read normally performed by a general radiologist.
From their press material:
Viz.ai demonstrated to CMS a significant reduction in time to treatment and improved clinical outcomes in patients suffering a stroke. Viz LVO has been granted a New Technology Add on Payment of up to&nb...
Source: The Health Care Blog - September 10, 2020 Category: Consumer Health News Authors: Christina Liu Tags: Artificial Intelligence Health Tech AI Luke Oakden-Rayner Reimbursement Source Type: blogs
Proposed guidelines likely to identify more early lung cancers
Lung cancer is the second most prevalent cancer in the US, and the deadliest cancer killer. In 2020, an estimated 135,720 people will die from the disease — more than breast, colon, and prostate cancers combined.
I’ll never forget meeting new, advanced-stage lung cancer patients who ask if their diagnosis could have somehow been made earlier, when treatment would have been more likely to succeed. In 2009, when I began practicing thoracic oncology, there were no approved screening tests for lung cancer.
A brief history of lung cancer screening
Hope for early detection and death prevention came in 2011 with the publicati...
Source: Harvard Health Blog - September 9, 2020 Category: Consumer Health News Authors: Inga Lennes, MD, MPH, MBA Tags: Cancer Lung disease Screening Source Type: blogs
Modified Simpson ’ s rule for LVEF
Modified Simpson’s rule for LVEF
Modified Simpson’s rule for LVEF
Modified Simpson’s rule for LVEF (left ventricular ejection fraction) is used not only in echocardiography, but also in cardiac magnetic resonance (CMR) imaging, left ventricular angiography and computed tomography (CT).
Basic assumption in Simpson’s rule is that the shape of the left ventricular cavity is a composite of a cylinder (from base to the level of the mitral valve), a truncated cone from mitral valve level to the level of the papillary muscles and a cone from there to the apex [1].
Volume of the cylinder: Am x L/3
Volume o...
Source: Cardiophile MD - September 6, 2020 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Angiography and Interventions Cardiac CT scan Cardiac Magnetic Resonance imaging Echocardiography Source Type: blogs
Exact Models of Aortic Heart Valves Help Prepare for Minimally Invasive Procedures
Complex transcatheter cardiac procedures, such as valve replacements, are often difficult to prepare for. Small anatomical differences can make big impacts on outcomes. Clinicians and researchers have been using models, both virtual and 3D printed, to improve procedural outcomes, design new devices, and to invent new therapeutic techniques. These models generally help professionals to understand nuances between patients, but they don’t reproduce the exact shapes and dynamics of moving tissues and structures.
Now researchers at the University of Minnesota, with help from Medtronic, have developed a way of 3D print...
Source: Medgadget - August 31, 2020 Category: Medical Devices Authors: Medgadget Editors Tags: Cardiac Surgery Cardiology Materials Radiology Source Type: blogs
Accordion sign – Cardiology MCQ – Answer
Accordion sign – Cardiology MCQ – Answer
Accordion sign on magnetic resonance imaging (MRI) is seen in – Correct answer: 3. Arrhythmogenic right ventricular cardiomyopathy
A focal crinkling of the right ventricular outflow tract and subtricuspid regions on MRI in arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVD/C) has been called “accordion sign” [1]. It was observed in 60% of the mutation carriers and none of those without the mutation (p < 0.001).
{Another accordion sign (also called concertina sign) has been described in computed tomography (CT) after administration of or...
Source: Cardiophile MD - August 24, 2020 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardiology MCQ DM / DNB Cardiology Entrance Source Type: blogs
I Cured My Patient, But What Was His Diagnosis?
By HANS DUVEFELT
He cancelled his followup appointment because he was feeling fine. He didn’t see the point in wasting a Saturday to come to my clinic when he had lawns to mow and chores to do.
Less than two weeks before that he was sitting on the exam table in my office, again and again nodding off, waking up surprised every time his wife prodded him. The stack of printouts from the emergency room illustrated all the normal testing they had done.
He had experienced a brief episode of numbness in the left side of his face and felt tired with just a slight headache. When I saw him the headache was a bit more ...
Source: The Health Care Blog - August 14, 2020 Category: Consumer Health News Authors: Christina Liu Tags: Medical Practice Physicians Primary Care Hans Duvefelt Source Type: blogs
