My patient and I were born on the same day. It took a tragedy to bring us back together.
It was a hot afternoon, but no dog day humidity yet. I was driving back from a satellite office when our nurse practitioner called. A patient with a condition we ’d seen many times before, a brain hemorrhage, her consciousness waning. The CT scan showed blood in the ventricles obstructing the flow of cerebrospinal fluid. TheRead more …My patient and I were born on the same day. It took a tragedy to bring us back together. originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - December 5, 2021 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/patrick-connolly" rel="tag" > Patrick Connolly, MD < /a > < /span > Tags: Physician Surgery Source Type: blogs

Fight Aging! Newsletter, November 8th 2021
In conclusion, in less common and visible cardiovascular diseases, it is crucial to recognize substantial progress and achievement, given that penetration of such information into clinical practice and the patient community can be inconsistent. Diseases such as hypertrophic cardiomyopathy, pulmonary arterial hypertension, and ATTR cardiac amyloidosis, once linked to a uniformly adverse prognosis, are now associated with the opportunity for patients to experience satisfactory quality of life and extended longevity. VitaDAO, a Novel Approach to Crowdfunding Life Science Research https://www.fightaging.org/archiv...
Source: Fight Aging! - November 7, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Agitation, Confusion, and Unusual Wide Complex Tachycardia. What is it, why did it occur, and how to treat?
A 50-something male ran a 10 mile race, after which he complained of a headache.  The next day, he collapsed and had a witnessed seizure.He arrived agitated and the monitor showed a wide complex tachycardia.  He was very hypertensive and tachycardic.A 12-lead ECG was obtained:What is it?  What therapy?There are wide complex QRS ' s with 2 different morphologies:1. RBBB configuration with an axis of about 135 degrees (lower right axis toward III)2. IVCD (neither RBBB nor LBBB) with a " Northwest " (upper right) axis toward aVRThere appear to be 3 possible P-waves, but they are not consistent and not definitel...
Source: Dr. Smith's ECG Blog - November 6, 2021 Category: Cardiology Authors: Steve Smith Source Type: blogs

How to Plan and Carry Out a Simple Self-Experiment, a Single Person Trial of Khavinson Peptides for Thymic Regrowth
The objective here is to produce doses of the peptides dissolved in 0.5 ml of phosphate buffered saline in sealed vials, ready to be used with the injection system, with as little contamination as possible from the environment, and stored a freezer until it is ready to use. Depending on the size of the vial, it might be able to contain doses for multiple injections, but it is better to stick to one dose per vial. Peptides are sensitive to free-thaw cycles, so you want as few of those as possible. When ordering epitalon, thymogen, and vilon, they will arrive as lyophilized (freeze-dried) crystals or powder. Thymogen ...
Source: Fight Aging! - November 1, 2021 Category: Research Authors: Reason Tags: Self-Experimentation Source Type: blogs

Doing Well
Still doing pretty well. I ' m currently taking Darzalex monthly, Pomalyst 2 mg daily (28 days of 28), and dexamethasone (Dex) 8 mg weekly. Monthly blood tests don ' t normally show any cause for concern, and I feel pretty good. Except lately calcium has been a bit high, and the doctors and I are paying some attention to that. Maybe a PET scan is due, or even a bone marrow biopsy, since my myeloma seems to have become "nonsecretory " (it may not secrete detectable immunoglobulin fragments). Ugh.I like a beer in the evening, but I skip that on Dex days and on the two days afterward. On infusion day I don ' t exercise a...
Source: Myeloma Hope - October 31, 2021 Category: Cancer & Oncology Tags: daratumumab Darzalex DEX dexamethasone pomalidomide Pomalyst Source Type: blogs

Wristband to Detect Strokes: Interview with Sandra Saldana, CEO of Alva Health
Alva Health, a medtech startup based in Connecticut, is developing a wristband that can detect the signs of stroke and promptly alert the wearer and/or healthcare staff. The technology is intended for those at high risk of stroke, such as stroke survivors and those diagnosed with transient ischemic attack. Strokes cause a huge level of patient morbidity every year, with many suffering debilitating symptoms that are life changing. Early diagnosis and prompt treatment are very important, but in many cases the early symptoms of a stroke are subtle and are easily missed. These issues have inspired this startup to develop a ...
Source: Medgadget - October 18, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Exclusive Neurology Neurosurgery alvahealth stroke Source Type: blogs

We Shouldn ’t Tolerate Sloppy Allergy Lists
By HANS DUVEFELT The medication and allergy lists seem like they would be the most important parts of a health record to keep current and accurate. But we all see errors too often. I think it shouldn’t be possible to enter an allergy without describing the reaction. Because without that information the list becomes completely useless. The other day I saw a patient who needed an urgent CT angiogram. The allergy list said “All Contrast Materials”, which isn’t even “structured data entry”, and thus not recognized by the computer if my EMR (Me again, Greenway!) would have been clever enough to check for al...
Source: The Health Care Blog - October 4, 2021 Category: Consumer Health News Authors: Christina Liu Tags: Medical Practice Primary Care Hans Duvefelt Source Type: blogs

Fight Aging! Newsletter, October 4th 2021
In conclusion, premature thymic involution and chronic inflammation greatly contribute to increased morbidity and mortality in CKD patients. Mechanisms are likely to be multiple and interlinked. Even when the quest to fountain of youth is a pipe dream, there are many scientific opportunities to prevent or to, at least in part, reverse CKD-related immune senescence. Further studies should precisely define most important pathways driving premature immune ageing in CKD patients and best therapeutic options to control them. Extending Life Without Extending Health: Vast Effort Directed to the Wrong Goals https://ww...
Source: Fight Aging! - October 3, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Swoop Portable MRI: Interview with David Scott, President and CEO of Hyperfine
Hyperfine, a company based in St Guilford, Connecticut, created Swoop, a portable MRI scanner. The device received FDA approval as the first bedside MRI scanner in 2020, and a recent study has shown that it can help to accurately spot hemorrhagic stroke, detecting 85 of 88 blood-negative cases (96.6% specificity). Rapid detection is important for successful treatment of strokes, and helps ensure the best outcomes for patients. The device can be wheeled up to a patient’s bed and powered through a standard wall outlet. This is beneficial for critically ill patients, who may be risky to move. Clinicians can acquire and v...
Source: Medgadget - October 1, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Emergency Medicine Neurology Orthopedic Surgery Pediatrics Radiology Source Type: blogs

Preclinical Atherosclerosis is Widespread in 50+ Year Old People
Atherosclerosis is the growth of fatty, inflamed deposits in blood vessel walls, narrowing and weakening them. It results from processes that are universal, present in every older individual. The oxidative stress and inflammation of aging lead to a raised amount of oxidized lipids and lipid carriers such as LDL particles, and these produce a growing dysfunction in the macrophage cells responsible for clearing unwanted lipids from blood vessel tissue. It is not surprising to see the data presented in today's research materials, showing that near half of older adults in their 50s and 60s age have measurable atheroscle...
Source: Fight Aging! - October 1, 2021 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Explainable A.I. Or Why You Need To Understand Machine Learning In Healthcare
A doctor in China uses a machine learning algorithm to detect signs of pneumonia associated with SARS-CoV-2 infections on images from lung CT scans. Epidemiologists in Canada are using the technology to monitor the spread of a disease and help prevent outbreaks. In the U.S., researchers are using artificial intelligence for more efficient drug discovery. Elsewhere around the world, patients are turning to their phones to access symptom checkers leveraging smart algorithms. These instances where medical professionals and patients alike employ artificial intelligence (A. I.) are already happening but in the coming years w...
Source: The Medical Futurist - September 28, 2021 Category: Information Technology Authors: Pranavsingh Dhunnoo Tags: Forecast Artificial Intelligence in Medicine Digital Health Research algorithm study deep learning machine learning A.I. npj Digital Medicine supervised learning reinforcement learning unsupervised learning Source Type: blogs

Policies, Techies, VCS: Musings From a Futurist
By IAN MORRISON I should’ve been in Paris last week on vacation with my wife, instead I listened in to the Policies Techies VCS:  What’s Next For Healthcare conference (I’ll explain why later).  Matthew Holt and Jessica DaMassa did a magnificent job of assembling the Who’s Who of digital health tech to wax lyrical about what the new kids on the block were up to, where it is all headed, and what it will mean for the system. (Full disclosure Matthew and Jess are friends of mine, I hired Matthew from Stanford almost 30 years ago to join the Institute For The Future (IFTF) and have watched proudly as he ha...
Source: The Health Care Blog - September 14, 2021 Category: Consumer Health News Authors: Christina Liu Tags: Health Policy Health Tech Futurists Ian Morrison Policies Techies VCs Source Type: blogs

How did all those calcium entered my father ’ s coronary artery doctor ?
“It was severe double vessel disease &  turned out to be a complex angioplasty in LAD ”  Why doctor? what happened? It was a hard lesion, there was plenty of calcium deposits. It was not clearly visible in the angiogram. I had to do IVUS. Curiously, the calcium was clustered in all the three planes of the vessel ( intima the media and adventitia) and they projected into the lumen blocking the path. Image collage representation purpose Thank you, doctor,  how did you manage to remove it,? It was a real struggle. I had to break the calcium shell before deploying the stent. (What we refer to as...
Source: Dr.S.Venkatesan MD - September 3, 2021 Category: Cardiology Authors: dr s venkatesan Tags: Cardiology -unresolved questions calcium supplementation coronary calcification intimal medial adventitial calcium ivl wolverine angiosculpt opn balloon orbitel atherectomy osteoporosis plaque calcium rotoablator serum calcium vs coron Source Type: blogs

3D-Printed Implant for Personalized Knee Realignments
Researchers at the University of Bath in the UK created a framework for 3D printing personalized high-tibial osteotomy (HTO) plates, using a titanium alloy, for knee realignments in osteoarthritis patients. The plates should fit nearly perfectly when implanted thanks to the new approach. The researchers have also developed an improved surgical technique, the TOKA (Tailored Osteotomy for Knee Alignment), which they claim should improve the fit of the HTO on the knee and significantly speed up HTO surgery from two hours to approximately 30 minutes. “Knee osteoarthritis is a major health, social and economic issue an...
Source: Medgadget - August 9, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Materials Orthopedic Surgery Source Type: blogs

Segmental approach to congenital heart disease
Segmental approach is used routinely in the echocardiographic evaluation of congenital heart disease. It is also useful in other cardiac imaging modalities used for evaluation of congenital heart disease like computed tomography and magnetic resonance imaging. Chest X-ray is useful in evaluating the cardiac position and visceral situs as it gives an overview of cardiac position in the thorax, position of left and right bronchi, aortic arch, liver and stomach air bubble [1]. Here is a chest X-ray in mesocardia with levo transposition of great arteries: X-ray chest PA showing mesocardia with L-TGA and L-posed aorta seen as ...
Source: Cardiophile MD - July 17, 2021 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Echocardiography Source Type: blogs