Monkeypox and the prolonged COVID pandemic could seal the fate of the health care system
I understand it’s been over two years since the World Health Organization announced the coronavirus pandemic, and we are tired. I speak for the thousands of health care workers and frontline workers: We are exhausted, we feel taken for granted, and for many of us, we are leaving the industry. In some cases, we went Read more… Monkeypox and the prolonged COVID pandemic could seal the fate of the health care system originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - August 8, 2022 Category: General Medicine Authors: Tags: Physician COVID Infectious Disease Source Type: blogs

Waiting for NHS hospital care: the role of the independent sector
The Health Foundation - Given the role anticipated for the independent sector in elective care recovery from the coronavirus pandemic, this long read explores the sector ’s role to date, looks at how this has changed since the pre-pandemic period, and considers what it might mean for patients waiting for different types of treatments, and living in different parts of England.Long read (Source: Health Management Specialist Library)
Source: Health Management Specialist Library - August 2, 2022 Category: UK Health Authors: The King ' s Fund Library Tags: Covid-19 NHS performance and productivity Source Type: blogs

Spray Coating Fights Viruses and Bacteria
Researchers at the University of Sydney in Australia engineered a new spray coating for surfaces that provides long-term protection against bacterial and viral contamination. The material is intended as a long-term alternative to disinfectant sprays and combines hydrophobic properties with antimicrobial nanoparticles to reduce microbial contamination. The hydrophobicity of the coating prevents liquid droplets from spreading over the surface, helping to prevent biofilm formation and microbial colonization. If the coating becomes damaged, reducing its hydrophobic properties, a second line of defense in the form of nanopa...
Source: Medgadget - August 1, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Materials Public Health Source Type: blogs

Fight Aging! Newsletter, August 1st 2022
In this study, we used the recently released Infinium Mouse Methylation BeadChip to compare such epigenetic modifications in C57BL/6 (B6) and DBA/2J (DBA) mice. We observed marked differences in age-associated DNA methylation in these commonly used inbred mouse strains, indicating that epigenetic clocks for one strain cannot be simply applied to other strains without further verification. Interestingly, the CpGs with highest age-correlation were still overlapping in B6 and DBA mice and included the genes Hsf4, Prima1, Aspa, and Wnt3a. Furthermore, Hsf4, Aspa, and Wnt3a revealed highly significant age-associated DNA methyla...
Source: Fight Aging! - July 31, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Autophagy as a Therapeutic Target
Plenty of evidence points to improvement in the cellular maintenance processes of autophagy (primarily macroautophagy and chaperone-mediated autophagy) as the primary mechanism by which the response to mild stress improves health and extends life. Autophagy recycles broken molecules and damaged structures in the cells. More recycling implies better function, a lesser burden of damage and dysfunction at any given time. This underlies the extension of life span resulting from calorie restriction, for example. Researchers are interested in the development of drugs that mimic these stress responses by artificially upregulating...
Source: Fight Aging! - July 29, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Face Mask Deactivates SARS-CoV-2 Spike Protein
Researchers at the University of Kentucky created a novel membrane that can enzymatically degrade the SARS-CoV-2 spike protein, rendering the virus inactive. The membrane is intended to act as an insert within face masks, providing extra protection for groups at high risk of SARS-CoV-2 exposure, such as health care staff. The researchers functionalized the membrane with subtilisin enzyme, which can degrade the spike protein in as little as 30 seconds. The masks could filter out as much as 95% of airborne particles, but the membranes may also be useful in air filtering technology that is designed to remove viral particles f...
Source: Medgadget - July 28, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Materials News Public Health SARS-CoV-2 universityofky Source Type: blogs

COVID: Higher Levels Of This Vitamin May Reduce Infection Risk
Having this vitamin above recommended levels may reduce the risk of coronavirus infection. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - July 27, 2022 Category: Psychiatry & Psychology Authors: Mina Dean Tags: COVID19 Source Type: blogs

The Macro View – Health, Economics, and Politics and the Big Picture. What I Am Watching Here And Abroad.
The objective most consistent with recent operations is to conquer Luhansk, Donetsk, and Kherson, with a view to their eventual annexation and Russification. But not only are they some way from achieving that (w ith much of Donetsk still in Ukrainian hands and the Russia position in Kherson highly contested) it would also require an explicit Ukrainian surrender for it to serve as the basis for a declaration of victory. That will not be forthcoming.-----https://www.afr.com/world/europe/how-britain-giggled-its-way-into-crisis-20220710-p5b0giHow Britain giggled its way into crisisBoris Johnson has exposed the costs of Britain...
Source: Australian Health Information Technology - July 21, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

Nanoparticle Vaccine for Many SARS-Like Coronaviruses
Researchers at the California Institute of Technology, better known as Caltech, have developed a nanoparticle vaccine that appears to confer broad protection against SARS-like betacoronaviruses. This includes SARS-CoV-2, responsible for the current pandemic, and SARS-CoV, which caused the original SARS pandemic in the early 2000s. The vaccine consists of protein nanoparticles that are studded with spike protein elements of eight different SARS-like betacoronaviruses, including SARS-CoV-2, but the researchers hope that it will confer broad immunity to new viral strains, including new and existing variants of SARS-Co...
Source: Medgadget - July 20, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Medicine Nanomedicine Public Health betacoronaviruses Caltech SARS-CoV Source Type: blogs

What's new in midwifery - 20th July 2022
Some things you may want to know about:First, consider submitting an abstract to theInternational Maternal Newborn Health Conference in Cape Town, May 2023. TheGuardian ' s report of plans to offer COVID boosters to the over 50s has a quote from the UKHSA that mentions pregnant women.  This made me look forGovernment information on the autumn booster programme, which does say that pregnant women are eligible.  The UKHSA quote encourages them to take up the offer.Then, athematic report from the National Child Mortality Database looking at the contribution of newborn health to child mortali...
Source: Browsing - July 20, 2022 Category: Databases & Libraries Tags: midwifery Source Type: blogs

TWiV 919: Motivated by volatiles
TWiV reviews the FDA decision to update COVID-19 vaccine boosters in the fall, the meaning of fatigue with respect to long COVID, and a skin volatile induced by flavivirus reproduction that attracts mosquitoes to the infected host. (Source: virology blog)
Source: virology blog - July 18, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology acetophenone antimicrobial peptide coronavirus COVID-19 FDA flavivirus Long Covid mosquito mosquito attractant Omicron booster pandemic SARS-CoV-2 skin microbiome vaccine viral viruses Source Type: blogs

TWiV 918: COVID-19 clinical update #123 with Dr. Daniel Griffin
In COVID-19 clinical update #123, Dr. Griffin discusses rapid diagnostic testing in response to the monkeypox outbreak, leading causes of death in the US during the COVID-19 pandemic, antibody evasion by subvariants, broadly-neutralizing antibodies against emerging variants, factors associated with severe outcomes among hospitalized immunocompromised adults, measurement of the burden of hospitalizations during the pandemic, parental vaccine hesitancy in diverse communities, evaluating saliva sampling to improve access to diagnosis in low-resource settings, oral sabizabulin for high-risk hospitalized adults, lower-risk of m...
Source: virology blog - July 16, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology antiviral coronavirus COVID-19 delta inflammation Long Covid monoclonal antibody Omicron pandemic SARS-CoV-2 vaccine vaccine booster variant of concern viruses Source Type: blogs

The #1 Risk Factor For COVID-19 Death
Researchers tracked nearly 17,000 patients admitted to UK hospitals for coronavirus treatment. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - July 9, 2022 Category: Psychiatry & Psychology Authors: Mina Dean Tags: COVID19 Source Type: blogs

Digital mental health intervention by the World Health Organization (WHO) found to lower anxiety and depression, with improvements maintained at 3 ‑month follow-up
Conclusions: In this study, we found that a guided, digital intervention was effective in reducing depression in displaced people in Lebanon. The guided WHO Step-by-Step intervention we examined should be made available to communities of displaced people that have digital access. The Study in Context: Headspace Health acquires AI-driven digital mental health start-up Sayana The landscape of digital mental health apps: huge unmet needs, quality concerns, app stores asked to ensure transparency The National Academy of Medicine (NAM) shares discussion paper to help empower 8 billion minds via the ethical adoption of digital...
Source: SharpBrains - July 5, 2022 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation anxiety depression digital mental health gratitude exercise mental-disorders positive self-talk post-traumatic stress stress-management well-being Source Type: blogs

TWiV 915: Mouse mouth to mouse mom
TWiV discusses the recent decision by an FDA advisory committee to update COVID vaccines for the fall, the monkeypox virus outbreak, and the finding that enteric viruses infect the salivary glands and are transmitted through saliva. (Source: virology blog)
Source: virology blog - July 3, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology coronavirus COVID-19 enteric virus norovirus pandemic rotavirus saliva saliva transmissions salivary gland SARS-CoV-2 vaccine variant of concern viral viruses Source Type: blogs