A look into the safety of children products following baby formula recalls
We previously reported about the national baby formula shortage that began in February 2022 and lasted for several months, affecting countless infants, parents, and caregivers and intensifying distress amid the ongoing COVID-19 pandemic. In fact, these supply chain disruptions were largely exacerbated by the novel coronavirus for numerous industries, including the food and infant care
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A look into the safety of children products following baby formula recalls originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - February 12, 2023 Category: General Medicine Authors: Divya Srinivasan and Tejas Sekhar Tags: Conditions Pediatrics Source Type: blogs
Fight Aging! Newsletter, January 30th 2023
In conclusion, deletion of p16Ink4a cells did not negatively impact beta-cell mass and blood glucose under basal and HFD conditions and proliferation was restored in a subset of HFD mice opening further therapeutic targets in the treatment of diabetes.
Communication Between Blood and Brain in Aging and Rejuvenation
https://www.fightaging.org/archives/2023/01/communication-between-blood-and-brain-in-aging-and-rejuvenation/
As noted here, joining the circulatory systems of an old and young mouse results in some degree of rejuvenation in the old mouse. Where brain function is improved, researchers are inte...
Source: Fight Aging! - January 29, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Towards Microneedle Delivery of LNP-mRNA Gene Therapies for Skin Aging
The skin is arguably one of the easiest of the large organs in the body to target for delivery of gene therapies, via established microneedle approaches. Nonetheless, much of the initial thrust of gene therapy clinical development focused instead on the liver, one of the other more tractable targets. Most material injected into the bloodstream ends up in the liver, and a single injection is logistically easier than coverage of large amounts of skin via microneedle patches, among other reasons.
Given the advent of messenger RNA (mRNA) encapsulated in lipid nanoparticles (either artificial or repurposed extracellular ...
Source: Fight Aging! - January 27, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
TWiV 975: Crossing the Ts with Daniela Weiskopf
Daniela joins TWiV to discuss her career and her research on T cells, their role in infection with SARS-CoV-2, T cell epitopes and why a variant that evades T cell immunity is not likely to emerge. Hosts: Vincent Racaniello, Alan Dove, and Brianne Barker Guest: Daniela Weiskopf Click arrow to playDownload TWiV 975 (58 MB .mp3, 98 […] (Source: virology blog)
Source: virology blog - January 15, 2023 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology coronavirus COVID-19 epitope Omicron pandemic SARS-CoV-2 T cell viral viruses Source Type: blogs
TWiV 975: Crossing the Ts with Daniela Weiskopf
Daniela joins TWiV to discuss her career and her research on T cells, their role in infection with SARS-CoV-2, T cell epitopes and why a variant that evades T cell immunity is not likely to emerge. Hosts: Vincent Racaniello, Alan Dove, and Brianne Barker Guest: Daniela Weiskopf Click arrow to playDownload TWiV 975 (58 MB .mp3, 98 … TWiV 975: Crossing the Ts with Daniela Weiskopf Read More » (Source: virology blog)
Source: virology blog - January 15, 2023 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology coronavirus COVID-19 epitope Omicron pandemic SARS-CoV-2 T cell viral viruses Source Type: blogs
Foobaw and more
Let me start with Damar Hamlin. His physicians haven ' t said anything publicly about what happened to him, but there are basically two possibilities. First, it is obviously uncommon but not unheard of for apparently healthy athletes to suffer cardiac arrest during exertion. This happened to Boston Celtics star Reggie Lewis. I happened to be in Boston Garden watching the first round playoff game against the Charlotte Hornets on April 29, 1993 when Lewis collapsed. All of the spectators were baffled about what had happened. Doctors at New England Baptist Hospital later diagnosed him with a heart abnormality...
Source: Stayin' Alive - January 6, 2023 Category: American Health Source Type: blogs
Going Viral
Helen Bramwell of StatNews is an excellent writer about public health. Here she interviews a bunch of scientists to ask what surprised them about Covid19. It ' s a long read, and I won ' t try to summarize it all, but a couple of points stand out.The first is that most experts originally thought, based on experience with other coronaviruses, that this one would be stable -- that it would not be able to mutate so as to avoid immunity from previous infections or vaccination. Therefore they believed that the pandemic would peak after a few months and we ' d enter an endemic phase. (You might remember those models from t...
Source: Stayin' Alive - December 30, 2022 Category: American Health Source Type: blogs
The Most Common Symptoms of Long COVID
Long COVID is when the symptoms from the novel coronavirus infection last longer than six weeks. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - December 28, 2022 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: COVID19 Source Type: blogs
COVID: Higher Levels Of This Vitamin May Reduce Infection Risk
Having this vitamin above recommended levels may reduce the risk of coronavirus infection. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - December 16, 2022 Category: Psychiatry & Psychology Authors: Mina Dean Tags: COVID19 Source Type: blogs
Fight Aging! Newsletter, December 12th 2022
In conclusion, selective removal of senescent dermal fibroblasts can improve the skin aging phenotype, indicating that BPTES may be an effective novel therapeutic agent for skin aging.
Non-Dividing Neurons Do In Fact Become Senescent, Impairing Brain Function
https://www.fightaging.org/archives/2022/12/non-dividing-neurons-do-in-fact-become-senescent-impairing-brain-function/
Cellular senescence is generally thought of as a characteristic of replicating cells; it is an end state reached when telomeres, reduced in length with each cell division, become too short. This is followed by programmed cell death...
Source: Fight Aging! - December 11, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
A Long Discussion of the Role of Senescent Cells in Idiopathic Pulmonary Fibrosis
Senescent cells are constantly created and destroyed throughout life, largely as a result of the replicative senescence that marks the end of life for a somatic cell, the Hayflick limit on cell division. With age, the pace of creation and destruction is disrupted, perhaps largely because the immune system ages to the point at which it falters in all of its tasks, clearance of senescent cells included. Senescent cells accumulate, and while never making up more than a small fraction of all somatic cells in any given tissue, the pro-growth, pro-inflammatory signaling generated by senescent cells is highly disruptive to organ ...
Source: Fight Aging! - December 9, 2022 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
The Top 20 Digital Health Trends For The Near Future: Here Is The 2022-23 Ebook
What is going to happen in the future of medicine? What will healthcare look like? And how will our roles change as healthcare goes increasingly digital? Which digital health trends are worthy of attention and which will prove to be just hype? These are some of the questions most often asked by healthcare professionals and industry experts.
In the 2022-23 update of The Top 20 Digital Health Trends For The Near Future we highlighted 20 developments likely to happen in the upcoming 2-5 years. They are based on our analyses of trends and relevant technologies that we have been constantly monitoring.
We would encourage ...
Source: The Medical Futurist - December 1, 2022 Category: Information Technology Authors: Pranavsingh Dhunnoo Tags: Forecast Digital Health Research alivecor ecg portable diagnostics telemedicine chatbots cdc around the pill Daichii-Sankyo coronavirus self checker Source Type: blogs
Fight Aging! Newsletter, November 28th 2022
This study explored whether determining the gain or loss of specific taxa represent a more precise metric of healthy/unhealthy aging than summary microbiome statistics, such as diversity and uniqueness. We analyzed microbiome diversity and four measures of microbiome uniqueness in 21,000 gut microbiomes for their relationship with aging and health. We show that diversity and uniqueness measures are not synonymous; uniqueness is not a uniformly desirable feature of the aging microbiome, nor is it an accurate biomarker of healthy aging. Different measures of uniqueness show different associations with diversity and with mark...
Source: Fight Aging! - November 27, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Targeting the Aging of the Immune System in the Context of Frailty
The immune system declines into a state of incapacity (immunosenescence) and chronic inflammation (inflammaging) with advancing age. Unresolved inflammatory signaling is disruptive of tissue function in many ways, from reduced stem cell activity to pathologically altered somatic cell behavior. It is thought to be important in the declining muscle mass and strength that contributes to age-related frailty. Thus addressing immune aging is a significant and important target in the treatment of aging as a whole.
Frailty is a highly prevalent geriatric syndrome that has attracted significant attention from physicians an...
Source: Fight Aging! - November 25, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Reducing Loneliness: How to Help Seniors During the Holidays
There is a lot of pressure on people to enjoy themselves during the holidays. The season is supposed to be merry and bright, but many elders feel increasingly isolated and unhappy this time of year—even before the coronavirus pandemic complicated everyday life and special occasions. Understandably, families are still concerned about how minimizing COVID-19 risk will affect their holiday plans with aging loved ones this year.
Why Seniors Experience Holiday Loneliness: While aging can bring wisdom and experience, there are inevitable losses that even the healthiest seniors face. Loved ones and friends fall il...
Source: Minding Our Elders - November 15, 2022 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs
